hRRN3 is essential in the SL1-mediated recruitment of RNA polymerase I to rRNA gene promoters

EMBO Journal

Volumn 20, Issue 6, 2001, Pages 1373-1382

  Miller, G ^a   Panov, K I ^a   Friedrich, J K ^a   Trinkle Mulcahy, L ^a   Lamond, A I ^a   Zomerdijk, J C B M ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Growth control; Holoenzyme; Nucleolus; rRNA; Transcription

Indexed keywords

DNA DIRECTED RNA POLYMERASE; HOLOENZYME; PROTEIN HRRN3; RIBOSOME RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SL1; UNCLASSIFIED DRUG;

ARTICLE; GENETIC TRANSCRIPTION; GROWTH REGULATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTERACTION; RNA GENE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

BINDING SITES; CELL NUCLEOLUS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HOLOENZYMES; HUMANS; MODELS, GENETIC; POL1 TRANSCRIPTION INITIATION COMPLEX PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RNA POLYMERASE I; RNA, RIBOSOMAL; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0035869039     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.6.1373     Document Type: Article

References (41)

1. Histone acetyltransferase and protein kinase activities copurify with a putative Xenopus RNA polymerase I holoenzyme self-sufficient for promoter-dependent transcription
2. Regulation of eukaryotic ribosomal RNA transcription by RNA polymerase modification
3. Coactivator and promoter-selective properties of RNA polymerase I TAFs
4. Transcription in Archaea
5. Functional cooperativity between transcription factors UBF1 and SL1 mediates human ribosomal RNA synthesis
6. TIF-IA, the factor mediating growth-dependent control of ribosomal RNA synthesis, is the mammalian homolog of yeast Rrn3p
7. Factor C*, the specific initiation component of the mouse RNA polymerase I holoenzyme, is inactivated early in the transcription process
8. Growth-dependent regulation of rRNA synthesis is mediated by a transcription initiation factor (TIF-IA)
9. The yeast RNA polymerase III transcription machinery: A paradigm for eukaryotic gene activation
10. The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SL1
11. Reconstitution of transcription factor SL1: Exclusive binding of TBP by SL1 or TFIID subunits
12. Animal DNA-dependent RNA polymerases. 10. General enzymatic properties of purified calf thymus RNA polymerases AI and B
13. Bacterial sigma factors
14. rRNA polymerase I associated factor 53 binds to the nucleolar transcription factor UBF and functions in specific rDNA transcription
15. Affinity purification of mammalian RNA polymerase I. Identification of an associated kinase
16. Identification of a mammalian RNA polymerase I holoenzyme containing components of the DNA repair/replication system
17. Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins
18. Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
19. Reconstitution of yeast RNA polymerase I transcription in vitro from purified components. TATA-binding protein is not required for basal transcription
20. Transcription factor IIIB: The architecture of its DNA complex and its roles in initiation of transcription by RNA polymerase III
21. Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations
22. In vitro transcription of human ribosomal RNA genes by RNA polymerase I
23. Purification and characterization of a transcription factor that confers promoter specificity to human RNA polymerase I
24. Human rRNA transcription is modulated by the coordinate binding of two factors to an upstream control element
25. Nucleolar DNA-dependent RNA polymerase from rat liver. 2. Two forms and their physiological significance
26. A specialized form of RNA polymerase I, essential for initiation and growth-dependent regulation of rRNA synthesis, is disrupted during transcription
27. RNA polymerase I transcription factor Rm3 is functionally conserved between yeast and human
28. The general transcription factors of RNA polymerase II
29. A step subsequent to pre-initiation complex assembly at the rDNA promoter is rate limiting for human RNA Polymerase I-dependent transcription
30. The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rm3
31. UBF, an architectural element for RNA polymerase I promoters
32. Extensive purification of a putative RNA polymerase I holoenzyme from plants that accurately initiates rRNA gene transcription in vitro
33. A growth-dependent transcription initiation factor (TIF-IA) interacting with RNA polymerase I regulates mouse ribosomal RNA synthesis
34. Function of the growth-regulated transcription initiation factor TIF-IA in initiation complex formation at the murine ribosomal gene promoter
35. The HMG box-containing nucleolar transcription factor UBF interacts with a specific subunit of RNA polymerase I
36. Purification and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase I from the mouse myeloma, MOPC 315
37. Mammalian RNA polymerase I exists as a holoenzyme with associated basal transcription factors
38. Transcription of mouse rDNA is regulated by an activated subform of RNA polymerase I
39. RRN3 gene of Saccharomyces cerevisiae encodes an essential RNA polymerase I transcription factor which interacts with the polymerase independently of DNA template
40. Structure and assembly of human selectivity factor SL1
41. Assembly of transcriptionally active RNA polymerase I initiation factor SL1 from recombinant subunits