Nucleophosmin/B23, a nuclear PI(3,4,5)P3 receptor, mediates the antiapoptotic actions of NGF by inhibiting CAD

Molecular Cell

Volumn 18, Issue 4, 2005, Pages 435-445

  Ahn, Jee Yin ^a,c   Liu, Xia ^a   Cheng, Dongmei ^a   Peng, Junmin ^a   Chan, Pui Kwang ^b   Wade, Paul A ^a   Ye, Keqiang ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c Sungkyunkwan University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CASPASE ACTIVATED DEOXYRIBONUCLEASE; DNA FRAGMENT; ENZYME; MUTANT PROTEIN; NERVE GROWTH FACTOR; NUCLEOPHOSMIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN; CONTROLLED STUDY; ENZYME INHIBITION; NONHUMAN; NUCLEUS ACCUMBENS; PROTEIN DEPLETION; PROTEIN EXPRESSION; RAT;

ANIMALS; APOPTOSIS; CELL NUCLEUS; DEOXYRIBONUCLEASES; DNA FRAGMENTATION; NERVE GROWTH FACTOR; NUCLEAR PROTEINS; PC12 CELLS; PHOSPHATIDYLINOSITOL PHOSPHATES; RATS;

EID: 18944395803     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2005.04.010     Document Type: Article

References (43)

1. N.N. Ahmed, T.F. Franke, A. Bellacosa, K. Datta, M.E. Gonzalez-Portal, T. Taguchi, J.R. Testa, and P.N. Tsichlis The proteins encoded by c-akt and v-akt differ in post-translational modification, subcellular localization and oncogenic potential Oncogene 8 1993 1957 1963
2. J.Y. Ahn, R. Rong, X. Liu, and K. Ye PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus EMBO J. 23 2004 3995 4006
3. M. Andjelkovic, D.R. Alessi, R. Meier, A. Fernandez, N.J. Lamb, M. Frech, P. Cron, P. Cohen, J.M. Lucocq, and B.A. Hemmings Role of translocation in the activation and function of protein kinase B J. Biol. Chem. 272 1997 31515 31524
4. D. Bacqueville, P. Deleris, C. Mendre, M.T. Pieraggi, H. Chap, G. Guillon, B. Perret, and M. Breton-Douillon Characterization of a G protein-activated phosphoinositide 3-kinase in vascular smooth muscle cell nuclei J. Biol. Chem. 276 2001 22170 22176
5. A. Bavelloni, S. Santi, A. Sirri, M. Riccio, I. Faenza, N. Zini, S. Cecchi, A. Ferri, P. Auron, N.M. Maraldi, and S. Marmiroli Phosphatidylinositol 3-kinase translocation to the nucleus is induced by interleukin 1 and prevented by mutation of interleukin 1 receptor in human osteosarcoma Saos-2 cells J. Cell Sci. 112 1999 631 640
6. R. Beckmann, K. Buchner, P.R. Jungblut, C. Eckerskorn, C. Weise, R. Hilbert, and F. Hucho Nuclear substrates of protein kinase C Eur. J. Biochem. 210 1992 45 51
7. D. Bertwistle, M. Sugimoto, and C.J. Sherr Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23 Mol. Cell. Biol. 24 2004 985 996
8. I.V. Boronenkov, J.C. Loijens, M. Umeda, and R.A. Anderson Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors Mol. Biol. Cell 9 1998 3547 3560
9. A. Brunet, S.R. Datta, and M.E. Greenberg Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway Curr. Opin. Neurobiol. 11 2001 297 305
10. J.H. Chang, J.Y. Lin, M.H. Wu, and B.Y. Yung Evidence for the ability of nucleophosmin/B23 to bind ATP Biochem. J. 329 1998 539 544
11. C.C. Chou, and B.Y. Yung Increased stability of nucleophosmin/B23 in anti-apoptotic effect of ras during serum deprivation Mol. Pharmacol. 59 2001 38 45
12. L. Cocco, A.M. Martelli, R.S. Gilmour, S.G. Rhee, and F.A. Manzoli Nuclear phospholipase C and signaling Biochim. Biophys. Acta 1530 2001 1 14
13. C.S. D'Santos, J.H. Clarke, and N. Divecha Phospholipid signalling in the nucleus. Een DAG uit het leven van de inositide signalering in de nucleus Biochim. Biophys. Acta 1436 1998 201 232
14. P. Deleris, D. Bacqueville, S. Gayral, L. Carrez, J.P. Salles, B. Perret, and M. Breton-Douillon SHIP-2 and PTEN are expressed and active in vascular smooth muscle cell nuclei, but only SHIP-2 is associated with nuclear speckles J. Biol. Chem. 278 2003 38884 38891
15. C. Fankhauser, E. Izaurralde, Y. Adachi, P. Wingfield, and U.K. Laemmli Specific complex of human immunodeficiency virus type 1 rev and nucleolar B23 proteins: dissociation by the Rev response element Mol. Cell. Biol. 11 1991 2567 2575
16. O. Gozani, P. Karuman, D.R. Jones, D. Ivanov, J. Cha, A.A. Lugovskoy, C.L. Baird, H. Zhu, S.J. Field, and S.L. Lessnick The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor Cell 114 2003 99 111
17. J.E. Herrera, J.J. Correia, A.E. Jones, and M.O. Olson Sedimentation analyses of the salt- and divalent metal ion-induced oligomerization of nucleolar protein B23 Biochemistry 35 1996 2668 2673
18. K. Hingorani, A. Szebeni, and M.O. Olson Mapping the functional domains of nucleolar protein B23 J. Biol. Chem. 275 2000 24451 24457
19. C.Y. Hsu, and B.Y. Yung Over-expression of nucleophosmin/B23 decreases the susceptibility of human leukemia HL-60 cells to retinoic acid-induced differentiation and apoptosis Int. J. Cancer 88 2000 392 400
20. K. Itahana, K.P. Bhat, A. Jin, Y. Itahana, D. Hawke, R. Kobayashi, and Y. Zhang Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation Mol. Cell 12 2003 1151 1164
21. J.L. Kam, K. Miura, T.R. Jackson, J. Gruschus, P. Roller, S. Stauffer, J. Clark, R. Aneja, and P.A. Randazzo Phosphoinositide-dependent activation of the ADP-ribosylation factor GTPase-activating protein ASAP1. Evidence for the pleckstrin homology domain functioning as an allosteric site J. Biol. Chem. 275 2000 9653 9663
22. Y.P. Li, R.K. Busch, B.C. Valdez, and H. Busch C23 interacts with B23, a putative nucleolar-localization-signal-binding protein Eur. J. Biochem. 237 1996 153 158
23. X. Liu, H. Zou, C. Slaughter, and X. Wang DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis Cell 89 1997 175 184
24. M. Marchisio, V. Bertagnolo, M.L. Colamussi, S. Capitani, and L.M. Neri Phosphatidylinositol 3-kinase in HL-60 nuclei is bound to the nuclear matrix and increases during granulocytic differentiation Biochem. Biophys. Res. Commun. 253 1998 346 351
25. A.M. Martelli, G. Tabellini, P. Borgatti, R. Bortul, S. Capitani, and L.M. Neri Nuclear lipids: new functions for old molecules? J. Cell. Biochem. 88 2003 455 461
26. R. Meier, D.R. Alessi, P. Cron, M. Andjelkovic, and B.A. Hemmings Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta J. Biol. Chem. 272 1997 30491 30497
27. S. Nagata Apoptotic DNA fragmentation Exp. Cell Res. 256 2000 12 18
28. L.M. Neri, D. Milani, L. Bertolaso, M. Stroscio, V. Bertagnolo, and S. Capitani Nuclear translocation of phosphatidylinositol 3-kinase in rat pheochromocytoma PC 12 cells after treatment with nerve growth factor Cell Mol. Biol. (Noisy-le-grand) 40 1994 619 626
29. L.M. Neri, P. Borgatti, S. Capitani, and A.M. Martelli Nuclear diacylglycerol produced by phosphoinositide-specific phospholipase C is responsible for nuclear translocation of protein kinase C-alpha J. Biol. Chem. 273 1998 29738 29744
30. M. Peter, J. Nakagawa, M. Doree, J.C. Labbe, and E.A. Nigg Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase Cell 60 1990 791 801
31. M. Pfaff, and F.A. Anderer Casein kinase II accumulation in the nucleolus and its role in nucleolar phosphorylation Biochim. Biophys. Acta 969 1988 100 109
32. D.J. Shapiro, P.A. Sharp, W.W. Wahli, and M.J. Keller A high-efficiency HeLa cell nuclear transcription extract DNA 7 1988 47 55
33. L.M. Sly, M.J. Rauh, J. Kalesnikoff, T. Buchse, and G. Krystal SHIP, SHIP2, and PTEN activities are regulated in vivo by modulation of their protein levels: SHIP is up-regulated in macrophages and mast cells by lipopolysaccharide Exp. Hematol. 31 2003 1170 1181
34. B.C. Valdez, L. Perlaky, D. Henning, Y. Saijo, P.K. Chan, and H. Busch Identification of the nuclear and nucleolar localization signals of the protein p120. Interaction with translocation protein B23 J. Biol. Chem. 269 1994 23776 23783
35. P. Villa, M. Miehe, M. Sensenbrenner, and B. Pettmann Synthesis of specific proteins in trophic factor-deprived neurons undergoing apoptosis J. Neurochem. 62 1994 1468 1475
36. D. Wang, A. Baumann, A. Szebeni, and M.O. Olson The nucleic acid binding activity of nucleolar protein B23.1 resides in its carboxyl-terminal end J. Biol. Chem. 269 1994 30994 30998
37. H. Wu, V. Goel, and F.G. Haluska PTEN signaling pathways in melanoma Oncogene 22 2003 3113 3122
38. M.H. Wu, C.Y. Lam, and B.Y. Yung Translocation of nucleophosmin from nucleoli to nucleoplasm requires ATP Biochem. J. 305 1995 987 992
39. M.H. Wu, J.H. Chang, and B.Y. Yung Resistance to UV-induced cell-killing in nucleophosmin/B23 over-expressed NIH 3T3 fibroblasts: enhancement of DNA repair and up-regulation of PCNA in association with nucleophosmin/B23 over-expression Carcinogenesis 23 2002 93 100
40. K.M. Yamada, and M. Araki Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis J. Cell Sci. 114 2001 2375 2382
41. T. Yokogawa, S. Nagata, Y. Nishio, T. Tsutsumi, S. Ihara, R. Shirai, K. Morita, M. Umeda, Y. Shirai, N. Saitoh, and Y. Fukui Evidence that 3′-phosphorylated polyphosphoinositides are generated at the nuclear surface: use of immunostaining technique with monoclonal antibodies specific for PI 3,4-P(2) FEBS Lett. 473 2000 222 226
42. B.Y. Yung, A.M. Bor, and P.K. Chan Short exposure to actinomycin D induces "reversible" translocation of protein B23 as well as "reversible" inhibition of cell growth and RNA synthesis in HeLa cells Cancer Res. 50 1990 5987 5991
43. N. Zini, A. Ognibene, S. Marmiroli, A. Bavelloni, M.C. Maltarello, I. Faenza, A. Valmori, and N.M. Maraldi The intranuclear amount of phospholipase C beta 1 decreases following cell differentiation in Friend cells, whereas gamma 1 isoform is not affected Eur. J. Cell Biol. 68 1995 25 34