Nuclear Akt interacts with B23/NPM and protects it from proteolytic cleavage, enhancing cell survival

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 43, 2008, Pages 16584-16589

  Sang, Bae Lee ^a   Xuan Nguyen, Truong L ^a   Choi, Joung Woo ^a   Lee, Kyung Hoon ^a   Cho, Sung Woo ^b   Liu, Zhixue ^c   Ye, Keqiang ^c   Bae, Sun Sik ^d   Ahn, Jee Yin ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Pusan National University School of Medicine   (South Korea)

Author keywords

Akt PKB; Caspase 3; Stability; Sumoylation

Indexed keywords

AMINO ACID; CASPASE 3; GROWTH FACTOR; NUCLEAR PROTEIN; NUCLEOPHOSMIN; PLECKSTRIN; PROTEIN KINASE B; PROTEIN KINASE B BETA;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL NUCLEUS; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RAT; SEQUENCE HOMOLOGY; SUMOYLATION; UPREGULATION;

ANIMALS; BINDING SITES; CASPASE 3; CELL CYCLE; CELL NUCLEUS; CELL SURVIVAL; CYTOPLASM; HIPPOCAMPUS; NUCLEAR PROTEINS; PC12 CELLS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; UBIQUITINATION;

EID: 55949109177     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0807668105     Document Type: Article

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