Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair

Journal of Biological Chemistry

Volumn 280, Issue 19, 2005, Pages 18771-18781

  Alt, Jodi R ^a,b   Bouska, Alyssa ^b   Fernandez, Mario R ^a   Cerny, Ronald L ^c   Xiao, Hua ^a,b   Eischen, Christine M ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CELLS; ENZYMES; GENETIC ENGINEERING; NEUTRON IRRADIATION; TUMORS;

BINDING DOMAIN; DNA DOUBLE STRANDS; TUMOR SUPPRESSOR;

DNA;

AMINO ACID; BETA ACTIN; COMPLEMENTARY DNA; DOUBLE STRANDED DNA; GLUTATHIONE TRANSFERASE; MRE11 PROTEIN; NIBRIN; PROTEIN; PROTEIN MDM2; PROTEIN P53; RAD50 PROTEIN; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; MDM2 PROTEIN, HUMAN; MDM2 PROTEIN, MOUSE; MRE11A PROTEIN, HUMAN; MRE11A PROTEIN, MOUSE; NBS1 PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; RAD50 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL STRAIN 3T3; CELL STRAIN K 562; CELL STRAIN MCF 7; DNA DAMAGE; DNA PROTEIN COMPLEX; DNA REPAIR; DNA STRAND BREAKAGE; GAMMA IRRADIATION; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MASS SPECTROMETRY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; FLUORESCENCE MICROSCOPY; GAMMA RADIATION; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; SILVER STAINING; TIME; TRANSGENIC MOUSE; TUMOR CELL LINE; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL LINE; CELL LINE, TUMOR; DNA DAMAGE; DNA REPAIR; DNA REPAIR ENZYMES; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; GAMMA RAYS; GLUTATHIONE TRANSFERASE; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; K562 CELLS; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTATION; NIH 3T3 CELLS; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; SEQUENCE HOMOLOGY, AMINO ACID; SILVER STAINING; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 21444444598     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413387200     Document Type: Article

References (59)

1. D'Amours, D., and Jackson, S. P. (2002) Nat. Rev. Mol. Cell. Biol. 3, 317-327
2. Paull, T. T., and Gellert, M. (1999) Genes Dev. 13, 1276-1288
3. Dolganov, G. M., Maser, R. S., Novikov, A., Tosto, L., Chong, S., Bressan, D. A., and Petrini, J. H. (1996) Mol. Cell. Biol. 16, 4832-4841
4. Carney, J. P., Maser, R. S., Olivares, H., Davis, E. M., Le Beau, M., Yates, J. R., III, Hays, L., Morgan, W. F., and Petrini, J. H. (1998) Cell 93, 477-486
5. Alani, E., Subbiah, S., and Kleckner, N. (1989) Genetics 122, 47-57
6. Desai-Mehta, A., Cerosaletti, K. M., and Concannon, P. (2001) Mol. Cell. Biol. 21, 2184-2191
7. Zhong, Q., Chen, C. F., Li, S., Chen, Y., Wang, C. C., Xiao, J., Chen, P. L., Sharp, Z. D., and Lee, W. H. (1999) Science 285, 747-750
8. Paull, T. T., Cortez, D., Bowers, B., Elledge, S. J., and Gellert, M. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 6086-6091
9. Stewart, G. S., Maser, R. S., Stankovic, T., Bressan, D. A., Kaplan, M. I., Jaspers, N. G., Raams, A., Byrd, P. J., Petrini, J. H., and Taylor, A. M. (1999) Cell 99, 577-587
10. Varon, R., Vissinga, C., Platzer, M., Cerosaletti, K. M., Chrzanowska, K. H., Saar, K., Beckmann, G., Seemanova, E., Cooper, P. R., Nowak, N. J., Stumm, M., Weemaes, C. M., Gatti, R. A., Wilson, R. K., Digweed, M., Rosenthal, A., Sperling, K., Concannon, P., and Reis, A. (1998) Cell 93, 467-476
11. Hiel, J. A., Weemaes, C. M., van den Heuvel, L. P., van Engelen, B. G., Gabreels, F. J., Smeets, D. F., van der Burgt, I., Chrzanovska, K. H., Bernatowska, E., Krajewska-Walasek, M., Bialecka, M., Abramczuk, D., Gregorek, H., Michalowski, J., Perek, D., Midro, A. T., Seemanova, E., Belohradsky, B. H., Solder, B., Barbi, G., Wegner, R. D., Sperling, K., Dixon, J., Maraschio, P., Marseglia, G. L., Green, A., Taylor, A. M., Der Kaloustian, V. M., Komatsu, K., Matsuura, S., Conley, M. E., Concannon, P., and Gatti, R. A. (2000) Arch. Dis. Child. 82, 400-406
12. Savitsky, K., Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y., Vanagaite, L., Tagle, D. A., Smith, S., Uziel, T., Sfez, S., Ashkenazi, M., Pecker, I., Frydman, M., Harnik, R., Patanjali, S. R., Simmons, A., Clines, G. A., Sartiel, A., Gatti, R. A., Chessa, L., Sanal, O., Lavin, M. F., Jaspers, N. G. J., Taylor, A. M. R., Arlett, C. F., Miki, T., Weissman, S. M., Lovett, M., Collins, F. S., and Shiloh, Y. (1995) Science 268, 1749-1753
13. Khosravi, R., Maya, R., Gottlieb, T., Oren, M., Shiloh, Y., and Shkedy, D. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 14973-14977
14. Lim, D. S., Kim, S. T., Xu, B., Maser, R. S., Lin, J., Petrini, J. H., and Kastan, M. B. (2000) Nature 404, 613-617
15. Costanzo, V., Robertson, K., Bibikova, M., Kim, E., Grieco, D., Gottesman, M., Carroll, D., and Gautier, J. (2001) Mol. Cell 8, 137-147
16. Gatei, M., Young, D., Cerosaletti, K. M., Desai-Mehta, A., Spring, K., Kozlov, S., Lavin, M. F., Gatti, R. A., Concannon, P., and Khanna, K. (2000) Nat. Genet. 25, 115-119
17. Canman, C. E., Lim, D.S., Cimprich, K. A., Taya, Y., Tamai, K., Sakaguchi, K., Appella, E., Kastan, M. B., and Siliciano, J. D. (1998) Science 281, 1677-1679
18. Zhao, S., Weng, Y. C., Yuan, S. S., Lin, Y. T., Hsu, H. C., Lin, S. C., Gerbino, E., Song, M. H., Zdzienicka, M. Z., Gatti, R. A., Shay, J. W., Ziv, Y., Shiloh, Y., and Lee, E. Y. (2000) Nature 405, 473-477
19. Fridman, J. S., and Lowe, S. W. (2003) Oncogene 22, 9030-9040
20. Momand, J., Zambetti, G. P., Olson, D. C., George, D., and Levine, A. J. (1992) Cell 69, 1237-1245
21. Honda, R., Tanaka, H., and Yasuda, H. (1997) FEBS Lett. 420, 25-27
22. Haupt, Y., Maya, R., Kazaz, A., and Oren, M. (1997) Nature 387, 296-299
23. Kubbutat, M. H., Jones, S. N., and Vousden, K. H. (1997) Nature 387, 299-303
24. Roth, J., Dobbelstein, M., Freedman, D. A., Shenk, T., and Levine, A. J. (1998) EMBO J. 17, 554-564
25. Jones, S. N., Roe, A. E., Donehower, L. A., and Bradley, A. (1995) Nature 378, 206-208
26. Montes de Oca Luna, R., Wagner, D. S., and Lozano, G. (1995) Nature 378, 203-206
27. Weber, J. D., Taylor, L. J., Roussel, M. F., Sherr, C. J., and Bar-Sagi, D. (1999) Nat. Cell Biol. 1, 20-26
28. Alt, J. R., Greiner, T, C., Cleveland, J. L., and Eischen, C. M. (2003) EMBO J. 22, 1442-1450
29. O'Leary, K. A., Mendrysa, S. M., Vaccaro, A., and Perry, M. E. (2004) Mol. Cell. Biol. 24, 186-191
30. Eischen, C. M., Alt, J. R., and Wang, P. (2004) Oncogene 23, 8931-8940
31. Jones, S. N., Hancock, A. R., Vogel, H., Donehower, L. A., and Bradley, A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 15608-15612
32. Lundgren, K., Montes de Oca Luna, R., McNeill, Y. B., Emerick, E. P., Spencer, B., Barfield, C. R., Lozano, G., Rosenberg, M. P., and Finlay, C. A. (1997) Genes Dev. 11, 714-725
33. Steinman, H. A., Burstein, E., Lengner, C., Gosselin, J., Pihan, G., Duckett, C. S., and Jones, S. N. (2004) J. Biol. Chem. 279, 4877-4886
34. Eischen, C. M., Weber, J. D., Roussel, M. F., Sherr, C. J., and Cleveland, J. L. (1999) Genes Dev. 13, 2658-2669
35. Watanabe, T., Ichikawa, A., Saito, H., and Hotta, T. (1996) Leuk. Lymphoma 21, 391-397
36. Wang, H., Yu, D., Agrawal, S., and Zhang, R. (2003) Prostate 54, 194-205
37. Shevchenko, A., Wilm, M., Vorm, O., and Mann, M. (1996) Anal. Chem. 68, 850-858
38. Zindy, F., Eischen, C. M., Randle, D. H., Kamijo, T., Cleveland, J. L., Sherr, C. J., and Roussel, M. F. (1998) Genes Dev. 12, 2424-2433
39. Dang, J., Kuo, M. L., Eischen, C. M., Stepanova, L., Sherr, C. J., and Roussel, M. F. (2002) Cancer Res. 62, 1222-1230
40. Dignam, J. D., Lebovitz, R. M., and Roeder, R. G. (1983) Nucleic Acids Res. 11, 1475-1489
41. Kobayashi, H., Sugiyama, C., Morikawa, Y., Hayashi, M., and Sofuni, T. (1995) MMS Commun. 103-115
42. Collins, A. R. (2004) Mol. Biotechnol. 26, 249-261
43. Cortez, D., Wang, Y., Qin, J., and Elledge, S. J. (1999) Science 286, 1162-1166
44. Tomlinson, G. E., Chen, T. T., Stastny, V. A., Virmani, A. K., Spillman, M. A., Tonk, V., Blum, J. L., Schneider, N. R., Wistuba, II, Shay, J. W., Minna, J. D., and Gazdar, A. F. (1998) Cancer Res. 58, 3237-3242
45. Iwakuma, T., and Lozano, G. (2003) Mol. Cancer Res. 1, 993-1000
46. Stracker, T. H., Carson, C. T., and Weitzman, M. D. (2002) Nature 418, 348-352
47. Maser, R. S., Zinkel, R., and Petrini, J. H. (2001) Nat. Genet. 27, 417-421
48. Mirzoeva, O. K., and Petrini, J. H. (2001) Mol. Cell. Biol. 21, 281-288
49. Paull, T. T., Rogakou, E. P., Yamazaki, V., Kirchgessner, C. U., Gellert, M., and Bonner, W. M. (2000) Curr. Biol. 10, 886-895
50. Carroll, P. E., Okuda, M., Horn, H. F., Biddinger, P., Stambrook, P. J., Gleich, L. L., Li, Y. Q., Tarapore, P., and Fukasawa, K. (1999) Oncogene 18, 1935-1944
51. Asahara, H., Li, Y., Fuss, J., Haines, D. S., Vlatkovic, N., Boyd, M. T., and Linn, S. (2003) Nucleic Acids Res. 31, 2451-2459
52. Celeste, A., Petersen, S., Romanienko, P. J., Fernandez-Capetillo, O., Chen, H. T., Sedelnikova, O. A., Reina-San-Martin, B., Coppola, V., Meffre, E., Difilippantonio, M. J., Redon, C., Pilch, D., R., Olaru, A., Eckhaus, M., Camerini-Otero, R. D., Tessarollo, L., Livak, F., Manova, K., Bonner, W. M., Nussenzweig, M. C., and Nussenzweig, A. (2002) Science 296, 922-927
53. Kobayashi, J., Tauchi, H., Sakamoto, S., Nakamura, A., Morishima, K., Matsuura, S., Kobayashi, T., Tamai, K., Tanimoto, K., and Komatsu, K. (2002) Curr. Biol. 12, 1846-1851
54. Lisby, M., Barlow, J. H., Burgess, R. C., and Rothstein, R. (2004) Cell 118, 699-713
55. Petrini, J. H., and Stracker, T. H. (2003) Trends Cell Biol. 13, 458-462
56. Carson, C. T., Schwartz, R. A., Stracker, T. H., Lilley, C. E., Lee, D. V., and Weitzman, M. D. (2003) EMBO J. 22, 6610-6620
57. Lee, J. H., and Paull, T. T. (2004) Science 304, 93-96
58. Uziel, T., Lerenthal, Y., Moyal, L., Andegeko, Y., Mittelman, L., and Shiloh, Y. (2003) EMBO J. 22, 5612-5621
59. Stommel, J. M., and Wahl, G. M. (2004) EMBO J. 23, 1547-1556