Nuclear speckles and nucleoli targeting by PIP2-PDZ domain interactions

EMBO Journal

Volumn 24, Issue 14, 2005, Pages 2556-2565

  Mortier, Eva ^a   Wuytens, Gunther ^a   Leenaerts, Iris ^a   Hannes, Femke ^a   Heung, Man Y ^b   Degeest, Gisèle ^a   David, Guido ^a   Zimmermann, Pascale ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Nuclear speckles; Nucleoli; PDZ domain; Phosphoinositides; Syntenin

Indexed keywords

PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POSTSYNAPTIC DENSITY PROTEIN 95; SYNTENIN 1; SYNTENIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL DIVISION; CELL MEMBRANE; CELL SURVIVAL; NONHUMAN; NUCLEOLUS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING;

CARRIER PROTEINS; CELL DIVISION; CELL LINE, TUMOR; CELL MEMBRANE; CELL NUCLEOLUS; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPID BILAYERS; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; SYNTENINS; TIME FACTORS;

EID: 23044468282     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600722     Document Type: Article

References (40)

1. Bae YS, Lee TG, Park JC, Hur JH, Kim Y, Heo K, Kwak JY, Suh PG, Ryu SH (2003) Identification of a compound that directly stimulates phospholipase C activity. Mol Pharmacol 63: 1043-1050
2. Bilder D, Schober M, Perrimon N (2003) Integrated activity of PDZ protein complexes regulates epithelial polarity. Nat Cell Biol 5: 53-58
3. Boronenkov IV, Loijens JC, Umeda M, Anderson RA (1998) Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors. Mol Biol Cell 9: 3547-3560
4. Borrell-Pages M, Fernandez-Larrea J, Borroto A, Rojo F, Baselga J, Arribas J (2000) The carboxy-terminal cysteine of the tetraspanin L6 antigen is required for its interaction with SITAC, a novel PDZ protein. Mol Biol Cell 11: 4217-4225
5. Cocco L, Martelli AM, Gilmour RS, Ognibene A, Manzoli FA, Irvine RF (1988) Rapid changes in phospholipid metabolism in the nuclei of Swiss 3T3 cells induced by treatment of the cells with insulin-like growth factor I. Biochem Biophys Res Commun 154: 1266-1272
6. Czech MP (2003) Dynamics of phosphoinositides in membrane retrieval and insertion. Annu Rev Physiol 65: 791-815
7. De Matteis MA, Godi A (2004) PI-loting membrane traffic. Nat Cell Biol 6: 487-492
8. Divecha N, Banfic H, Irvine RF (1991) The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus. EMBO J 10: 3207-3214
9. Divecha N, Banfic H, Irvine RF (1993) Inositides and the nucleus and inositides in the nucleus. Cell 74: 405-407
10. Gozani O, Karuman P, Jones DR, Ivanov D, Cha J, Lugovskoy AA, Baird CL, Zhu H, Field SJ, Lessnick SL, Villasenor J, Mehrotra B, Chen J, Rao VR, Brugge JS, Ferguson CG, Payrastre B, Myszka DG, Cantley LC, Wagner G, Divecha N, Prestwich GD, Yuan J (2003) The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell 114: 99-111
11. Grootjans JJ, Reekmans G, Ceulemans H, David G (2000) Syntenin-syndecan binding requires syndecan-synteny and the cooperation of both PDZ domains of syntenin. J Biol Chem 275: 19933-19941
12. Grootjans JJ, Zimmermann P, Reekmans G, Smets A, Degeest G, Durr J, David G (1997) Syntenin, a PDZ protein that binds syndecan cytoplasmic domains. Proc Natl Acad Sci USA 94: 13683-13688
13. Haaf T, Ward DC (1996) Inhibition of RNA polymerase II transcription causes chromatin decondensation, loss of nucleolar structure, and dispersion of chromosomal domains. Exp Cell Res 224: 163-173
14. Haas M, Jost E (1993) Functional analysis of phosphorylation sites in human lamin A controlling lamin disassembly, nuclear transport and assembly. Eur J Cell Biol 62: 237-247
15. Honda A, Nogami M, Yokozeki T, Yamazaki M, Nakamura H, Watanabe H, Kawamoto K, Nakayama K, Morris AJ, Frohman MA, Kanaho Y (1999) Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation. Cell 99: 521-532
16. Hung AY, Sheng M (2002) PDZ domains: structural modules for protein complex assembly. J Biol Chem 277: 5699-5702
17. Irvine RF (2003) Nuclear lipid signalling. Nat Rev Mol Cell Biol 4: 349-360
18. Jones DR, Divecha N (2004) Linking lipids to chromatin. Curr Opin Genet Dev 14: 196-202
19. Kachel N, Erdmann KS, Kremer W, Wolff P, Gronwald W, Heumann R, Kalbitzer HR (2003) Structure determination and ligand interactions of the PDZ2b domain of PTP-Bas (hPTP1E): splicing-induced modulation of ligand specificity. J Mol Biol 334: 143-155
20. Koroll M, Rathjen FG, Volkmer H (2001) The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity. J Biol Chem 276: 10646-10654
21. Lamond AI, Spector DL (2003) Nuclear speckles: a model for nuclear organelles. Nat Rev Mol Cell Biol 4: 605-612
22. Lemmon MA (2003) Phosphoinositide recognition domains. Traffic 4: 201-213
23. Maraldi NM, Zini N, Santi S, Manzoli FA (1999) Topology of inositol lipid signal transduction in the nucleus. J Cell Physiol 181: 203-217
24. Martelli AM, Manzoli L, Cocco L (2004) Nuclear inositides: facts and perspectives. Pharmacol Ther 101: 47-64
25. Nourry C, Grant SG, Borg JP (2003) PDZ domain proteins: plug and play!. Sci STKE 2003: RE7
26. Okada M, Fujii M, Yamaga M, Sugimoto H, Sadano H, Osumi T, Kamata H, Hirata H, Yagisawa H (2002) Carboxyl-terminal basic amino acids in the X domain are essential for the nuclear import of phospholipase C delta1. Genes Cells 7: 985-996
27. Osborne SL, Thomas CL, Gschmeissner S, Schiavo G (2001) Nuclear PtdIns(4,5)P2 assembles in a mitotically regulated particle involved in pre-mRNA splicing. J Cell Sci 114: 2501-2511
28. Roh MH, Margolis B (2003) Composition and function of PDZ protein complexes during cell polarization. Am J Physiol Renal Physiol 285: F377-F387
29. Sheng M, Sala C (2001) PDZ domains and the organization of supramolecular complexes. Annu Rev Neurosci 24: 1-29
30. Skare P, Kreivi JP, Bergstrom A, Karlsson R (2003) Profilin I colocalizes with speckles and Cajal bodies: a possible role in pre-mRNA splicing. Exp Cell Res 286: 12-21
31. Tang Y, Tang J, Chen Z, Trost C, Flockerzi V, Li M, Ramesh V, Zhu MX (2000) Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF. J Biol Chem 275: 37559-37564
32. Toker A (2002) Phosphoinositides and signal transduction. Cell Mol Life Sci 59: 761-779
33. 3H]inositol-labeled phosphoinositide pools. J Cell Biol 143: 501-510
34. Varnai P, Lin X, Lee SB, Tuymetova G, Bondeva T, Spat A, Rhee SG, Hajnoczky G, Balla T (2002) Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C delta 1 and p130. J Biol Chem 277: 27412-27422
35. York JD, Odom AR, Murphy R, Ives EB, Wente SR (1999) A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. Science 285: 96-100
36. Yu H, Fukami K, Watanabe Y, Ozaki C, Takenawa T (1998) Phosphatidylinositol 4,5-bisphosphate reverses the inhibition of RNA transcription caused by histone H1. Eur J Biochem 251: 281-287
37. Yu JW, Mendrola JM, Audhya A, Singh S, Keleti D, DeWald DB, Murray D, Emr SD, Lemmon MA (2004) Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains. Mol Cell 13: 677-688
38. Zhao K, Wang W, Rando OJ, Xue Y, Swiderek K, Kuo A, Crabtree GR (1998) Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell 95: 625-636
39. Zimmermann P, Meerschaert K, Reekmans G, Leenaerts I, Small JV, Vandekerckhove J, David G, Gettemans J (2002) PIP(2)-PDZ domain binding controls the association of syntenin with the plasma membrane. Mol Cell 9: 1215-1225
40. Zimmermann P, Tomatis D, Rosas M, Grootjans J, Leenaerts I, Degeest G, Reekmans G, Coomans C, David G (2001) Characterization of syntenin, a syndecan-binding PDZ protein, as a component of cell adhesion sites and microfilaments. Mol Biol Cell 12: 339-350