Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets

Human Molecular Genetics

Volumn 24, Issue 18, 2015, Pages 5270-5284

  Brun, Thierry ^a   Li, Ning ^a   Jourdain, Alexis A ^a   Gaudet, Pascale ^a,b   Duhamel, Dominique ^a   Meyer, Jérémy ^c   Bosco, Domenico ^c   Maechler, Pierre ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; GLUCOSE; GLUTAMIC ACID; MALIC ACID; MITOCHONDRIAL DNA; OLEIC ACID; PALMITIC ACID; SIRTUIN 1; TRANSCRIPTOME; UNCOUPLING PROTEIN 2; INSULIN; PROTON PUMP; SUPEROXIDE;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DIABETOGENESIS; DOWN REGULATION; ENERGY; FEMALE; GLUCOTOXICITY; HUMAN; HUMAN CELL; INNER MEMBRANE; INSULIN RELEASE; LONG TERM EXPOSURE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; OXIDATIVE STRESS; PANCREAS ISLET; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY CHAIN; APOPTOSIS; CELL LINE; CELL SURVIVAL; CYTOLOGY; DIABETES MELLITUS; ELECTRON TRANSPORT; GENE EXPRESSION; GENETICS; METABOLISM;

APOPTOSIS; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; DIABETES MELLITUS; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT; GENE EXPRESSION; GLUCOSE; HUMANS; INSULIN; ISLETS OF LANGERHANS; MITOCHONDRIA; PROTON PUMPS; SUPEROXIDES; TRANSCRIPTOME;

EID: 84940663541     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv247     Document Type: Article

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