Mitochondrial glutathione transport is a key determinant of neuronal susceptibility to oxidative and nitrosative stress

Journal of Biological Chemistry

Volumn 288, Issue 7, 2013, Pages 5091-5101

  Wilkins, Heather M ^a   Kirchhof, Danielle ^a   Manning, Evan ^a   Joseph, Jamie W ^b   Linseman, Daniel A ^a,c,d  

^a UNIVERSITY OF DENVER   (United States)

^b UNIVERSITY OF WATERLOO   (Canada)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEREBELLAR NEURONS; KEY DETERMINANTS; MITOCHONDRIAL GLUTATHIONE; NITROSATIVE STRESS;

PEPTIDES;

NEURONS;

2 OXOGLUTARIC ACID; DICARBOXYLIC ACID; GLUTATHIONE; MALONIC ACID DERIVATIVE; N BUTYLMALONIC ACID; PHENYLSUCCINATE; SUCCINIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL DIFFERENTIATION; CELL PROTECTION; CELL VIABILITY; CEREBELLAR GRANULE NEURON; CONTROLLED STUDY; GLUTATHIONE METABOLISM; GLUTATHIONE TRANSPORT; IMMUNOFLUORESCENCE; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE; NERVE CELL; NERVE DEGENERATION; NEUROPROTECTION; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; RAT;

ANIMALS; ASTROCYTES; BIOLOGICAL TRANSPORT; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CYTOSOL; FREE RADICALS; GLUTATHIONE; MALONATES; MITOCHONDRIA; MODELS, BIOLOGICAL; NEURONS; NITROGEN; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SUCCINATES;

EID: 84874045170     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.405738     Document Type: Article

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