A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes

Diabetes

Volumn 52, Issue 10, 2003, Pages 2461-2474

  Kashyap, Sangeeta ^a   Belfort, Renata ^a   Gastaldelli, Amalia ^a   Pratipanawatr, Thongchai ^d   Berria, Rachele ^a   Pratipanawatr, Wilailak ^a   Bajaj, Mandeep ^a   Mandarino, Lawrence ^a   DeFronzo, Ralph ^a,b   Cusi, Kenneth ^a,b,c  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; FATTY ACID; GLUCOSE; INSULIN; LIPID;

ADULT; ARTICLE; CELL FUNCTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FAMILY HISTORY; FATTY ACID BLOOD LEVEL; FEMALE; GLUCONEOGENESIS; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HORMONE ACTION; HORMONE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; HYPERGLYCEMIA; INFUSION; INSULIN RELEASE; INSULIN RESISTANCE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NORMAL HUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; DRUG ADMINISTRATION SCHEDULE; FAT EMULSIONS, INTRAVENOUS; FATTY ACIDS, NONESTERIFIED; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; HORMONES; HUMANS; HYPERGLYCEMIA; INFUSIONS, INTRAVENOUS; INSULIN; MALE; OSMOLAR CONCENTRATION; REFERENCE VALUES; TIME FACTORS;

EID: 0141755328     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.10.2461     Document Type: Article

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