-
1
-
-
77953941543
-
Role of mitochondria in beta-cell function and dysfunction
-
Maechler P, Li N, Casimir M, Vetterli L, Frigerio F, et al. (2010) Role of mitochondria in beta-cell function and dysfunction. Adv Exp Med Biol 654: 193-216.
-
(2010)
Adv Exp Med Biol
, vol.654
, pp. 193-216
-
-
Maechler, P.1
Li, N.2
Casimir, M.3
Vetterli, L.4
Frigerio, F.5
-
2
-
-
7244248787
-
13C NMR isotopomer analysis of anaplerotic pathways in INS-1 cells
-
Cline GW, Lepine RL, Papas KK, Kibbey RG, Shulman GI (2004) 13C NMR isotopomer analysis of anaplerotic pathways in INS-1 cells. J Biol Chem 279: 44370-44375.
-
(2004)
J Biol Chem
, vol.279
, pp. 44370-44375
-
-
Cline, G.W.1
Lepine, R.L.2
Papas, K.K.3
Kibbey, R.G.4
Shulman, G.I.5
-
4
-
-
84867507940
-
The molecular mechanisms of pancreatic beta-cell glucotoxicity: Recent findings and future research directions
-
Bensellam M, Laybutt DR, Jonas JC (2012) The molecular mechanisms of pancreatic beta-cell glucotoxicity: recent findings and future research directions. Mol Cell Endocrinol 364: 1-27.
-
(2012)
Mol Cell Endocrinol
, vol.364
, pp. 1-27
-
-
Bensellam, M.1
Laybutt, D.R.2
Jonas, J.C.3
-
5
-
-
0031054064
-
Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1
-
Brun T, Assimacopoulos-Jeannet F, Corkey BE, Prentki M (1997) Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1. Diabetes 46: 393-400.
-
(1997)
Diabetes
, vol.46
, pp. 393-400
-
-
Brun, T.1
Assimacopoulos-Jeannet, F.2
Corkey, B.E.3
Prentki, M.4
-
6
-
-
33748521964
-
The antiepileptic drug topiramate preserves metabolism-secretion coupling in insulin secreting cells chronically exposed to the fatty acid oleate
-
Frigerio F, Chaffard G, Berwaer M, Maechler P (2006) The antiepileptic drug topiramate preserves metabolism-secretion coupling in insulin secreting cells chronically exposed to the fatty acid oleate. Biochem Pharmacol 72: 965-973.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 965-973
-
-
Frigerio, F.1
Chaffard, G.2
Berwaer, M.3
Maechler, P.4
-
7
-
-
0042922453
-
Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death
-
El-Assaad W, Buteau J, Peyot ML, Nolan C, Roduit R, et al. (2003) Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death. Endocrinology 144: 4154-4163.
-
(2003)
Endocrinology
, vol.144
, pp. 4154-4163
-
-
El-Assaad, W.1
Buteau, J.2
Peyot, M.L.3
Nolan, C.4
Roduit, R.5
-
8
-
-
0035156817
-
Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function
-
Maedler K, Spinas GA, Dyntar D, Moritz W, Kaiser N, et al. (2001) Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function. Diabetes 50: 69-76.
-
(2001)
Diabetes
, vol.50
, pp. 69-76
-
-
Maedler, K.1
Spinas, G.A.2
Dyntar, D.3
Moritz, W.4
Kaiser, N.5
-
9
-
-
9244231766
-
Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: Role of nuclear factor-kappaB and endoplasmic reticulum stress
-
Kharroubi I, Ladriere L, Cardozo AK, Dogusan Z, Cnop M, et al. (2004) Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress. Endocrinology 145: 5087-5096.
-
(2004)
Endocrinology
, vol.145
, pp. 5087-5096
-
-
Kharroubi, I.1
Ladriere, L.2
Cardozo, A.K.3
Dogusan, Z.4
Cnop, M.5
-
10
-
-
84874047426
-
Role of the saturated nonesterified fatty acid palmitate in beta cell dysfunction
-
Maris M, Robert S, Waelkens E, Derua R, Hernangomez MH, et al. (2013) Role of the saturated nonesterified fatty acid palmitate in beta cell dysfunction. J Proteome Res 12: 347-362.
-
(2013)
J Proteome Res
, vol.12
, pp. 347-362
-
-
Maris, M.1
Robert, S.2
Waelkens, E.3
Derua, R.4
Hernangomez, M.H.5
-
11
-
-
84876934840
-
Coordinate changes in histone modifications, mRNA levels, and metabolite profiles in clonal INS-1 832/13 beta-cells accompany functional adaptations to lipotoxicity
-
Malmgren S, Spegel P, Danielsson AP, Nagorny CL, Andersson LE, et al. (2013) Coordinate changes in histone modifications, mRNA levels, and metabolite profiles in clonal INS-1 832/13 beta-cells accompany functional adaptations to lipotoxicity. J Biol Chem 288: 11973-11987.
-
(2013)
J Biol Chem
, vol.288
, pp. 11973-11987
-
-
Malmgren, S.1
Spegel, P.2
Danielsson, A.P.3
Nagorny, C.L.4
Andersson, L.E.5
-
12
-
-
0037230114
-
Mitochondrial dysfunction is involved in apoptosis induced by serum withdrawal and fatty acids in the beta-cell line INS-1
-
Maestre I, Jordan J, Calvo S, Reig JA, Cena V, et al. (2003) Mitochondrial dysfunction is involved in apoptosis induced by serum withdrawal and fatty acids in the beta-cell line INS-1. Endocrinology 144: 335-345.
-
(2003)
Endocrinology
, vol.144
, pp. 335-345
-
-
Maestre, I.1
Jordan, J.2
Calvo, S.3
Reig, J.A.4
Cena, V.5
-
13
-
-
77954595108
-
Glucolipotoxicity alters lipid partitioning and causes mitochondrial dysfunction, cholesterol, and ceramide deposition and reactive oxygen species production in INS832/13 ss-cells
-
El-Assaad W, Joly E, Barbeau A, Sladek R, Buteau J, et al. (2010) Glucolipotoxicity alters lipid partitioning and causes mitochondrial dysfunction, cholesterol, and ceramide deposition and reactive oxygen species production in INS832/13 ss-cells. Endocrinology 151: 3061-3073.
-
(2010)
Endocrinology
, vol.151
, pp. 3061-3073
-
-
El-Assaad, W.1
Joly, E.2
Barbeau, A.3
Sladek, R.4
Buteau, J.5
-
14
-
-
53849129224
-
The sensitivity of pancreatic beta-cells to mitochondrial injuries triggered by lipotoxicity and oxidative stress
-
Li N, Frigerio F, Maechler P (2008) The sensitivity of pancreatic beta-cells to mitochondrial injuries triggered by lipotoxicity and oxidative stress. Biochem Soc Trans 36: 930-934.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 930-934
-
-
Li, N.1
Frigerio, F.2
Maechler, P.3
-
15
-
-
0033600762
-
Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells
-
Maechler P, Jornot L, Wollheim CB (1999) Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells. J Biol Chem 274: 27905-27913.
-
(1999)
J Biol Chem
, vol.274
, pp. 27905-27913
-
-
Maechler, P.1
Jornot, L.2
Wollheim, C.B.3
-
16
-
-
69949132408
-
Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction
-
Li N, Brun T, Cnop M, Cunha DA, Eizirik DL, et al. (2009) Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction. J Biol Chem 284: 23602-23612.
-
(2009)
J Biol Chem
, vol.284
, pp. 23602-23612
-
-
Li, N.1
Brun, T.2
Cnop, M.3
Cunha, D.A.4
Eizirik, D.L.5
-
17
-
-
77449154126
-
Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes
-
Lu H, Koshkin V, Allister EM, Gyulkhandanyan AV, Wheeler MB (2010) Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes. Diabetes 59: 448-459.
-
(2010)
Diabetes
, vol.59
, pp. 448-459
-
-
Lu, H.1
Koshkin, V.2
Allister, E.M.3
Gyulkhandanyan, A.V.4
Wheeler, M.B.5
-
18
-
-
79953249623
-
Evolution, structure and function of mitochondrial carriers: A review with new insights
-
Palmieri F, Pierri CL, De Grassi A, Nunes-Nesi A, Fernie AR (2011) Evolution, structure and function of mitochondrial carriers: a review with new insights. Plant J 66: 161-181.
-
(2011)
Plant J
, vol.66
, pp. 161-181
-
-
Palmieri, F.1
Pierri, C.L.2
De Grassi, A.3
Nunes-Nesi, A.4
Fernie, A.R.5
-
19
-
-
84875218644
-
The mitochondrial transporter family SLC25: Identification, properties and physiopathology
-
Palmieri F (2013) The mitochondrial transporter family SLC25: identification, properties and physiopathology. Mol Aspects Med 34: 465-484.
-
(2013)
Mol Aspects Med
, vol.34
, pp. 465-484
-
-
Palmieri, F.1
-
20
-
-
46349088952
-
Diseases caused by defects of mitochondrial carriers: A review
-
Palmieri F (2008) Diseases caused by defects of mitochondrial carriers: a review. Biochim Biophys Acta 1777: 564-578.
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 564-578
-
-
Palmieri, F.1
-
21
-
-
69949115837
-
Mitochondrial glutamate carrier GC1 as a newly identified player in the control of glucose-stimulated insulin secretion
-
Casimir M, Lasorsa FM, Rubi B, Caille D, Palmieri F, et al. (2009) Mitochondrial glutamate carrier GC1 as a newly identified player in the control of glucose-stimulated insulin secretion. J Biol Chem 284: 25004-25014.
-
(2009)
J Biol Chem
, vol.284
, pp. 25004-25014
-
-
Casimir, M.1
Lasorsa, F.M.2
Rubi, B.3
Caille, D.4
Palmieri, F.5
-
22
-
-
73149118482
-
Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets
-
Casimir M, Rubi B, Frigerio F, Chaffard G, Maechler P (2009) Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets. Biochem J 424: 459-466.
-
(2009)
Biochem J
, vol.424
, pp. 459-466
-
-
Casimir, M.1
Rubi, B.2
Frigerio, F.3
Chaffard, G.4
Maechler, P.5
-
23
-
-
33845971563
-
The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion
-
Joseph JW, Jensen MV, Ilkayeva O, Palmieri F, Alarcon C, et al. (2006) The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion. J Biol Chem 281: 35624-35632.
-
(2006)
J Biol Chem
, vol.281
, pp. 35624-35632
-
-
Joseph, J.W.1
Jensen, M.V.2
Ilkayeva, O.3
Palmieri, F.4
Alarcon, C.5
-
24
-
-
77952779747
-
The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion
-
Odegaard ML, Joseph JW, Jensen MV, Lu D, Ilkayeva O, et al. (2010) The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion. J Biol Chem 285: 16530-16537.
-
(2010)
J Biol Chem
, vol.285
, pp. 16530-16537
-
-
Odegaard, M.L.1
Joseph, J.W.2
Jensen, M.V.3
Lu, D.4
Ilkayeva, O.5
-
25
-
-
79953775104
-
The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin secretion from rat pancreatic beta cells
-
Huypens P, Pillai R, Sheinin T, Schaefer S, Huang M, et al. (2011) The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin secretion from rat pancreatic beta cells. Diabetologia 54: 135-145.
-
(2011)
Diabetologia
, vol.54
, pp. 135-145
-
-
Huypens, P.1
Pillai, R.2
Sheinin, T.3
Schaefer, S.4
Huang, M.5
-
26
-
-
79953203177
-
Role of mitochondrial phosphate carrier in metabolism-secretion coupling in rat insulinoma cell line INS-1
-
Nishi Y, Fujimoto S, Sasaki M, Mukai E, Sato H, et al. (2011) Role of mitochondrial phosphate carrier in metabolism-secretion coupling in rat insulinoma cell line INS-1. Biochem J 435: 421-430.
-
(2011)
Biochem J
, vol.435
, pp. 421-430
-
-
Nishi, Y.1
Fujimoto, S.2
Sasaki, M.3
Mukai, E.4
Sato, H.5
-
27
-
-
0033560073
-
Free radical modulation of insulin release in INS-1 cells exposed to alloxan
-
Janjic D, Maechler P, Sekine N, Bartley C, Annen AS, et al. (1999) Free radical modulation of insulin release in INS-1 cells exposed to alloxan. Biochem Pharmacol 57: 639-648.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 639-648
-
-
Janjic, D.1
Maechler, P.2
Sekine, N.3
Bartley, C.4
Annen, A.S.5
-
28
-
-
0842291578
-
Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells
-
Merglen A, Theander S, Rubi B, Chaffard G, Wollheim CB, et al. (2004) Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells. Endocrinology 145: 667-678.
-
(2004)
Endocrinology
, vol.145
, pp. 667-678
-
-
Merglen, A.1
Theander, S.2
Rubi, B.3
Chaffard, G.4
Wollheim, C.B.5
-
29
-
-
0026550830
-
Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines
-
Asfari M, Janjic D, Meda P, Li G, Halban PA, et al. (1992) Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 130: 167-178.
-
(1992)
Endocrinology
, vol.130
, pp. 167-178
-
-
Asfari, M.1
Janjic, D.2
Meda, P.3
Li, G.4
Halban, P.A.5
-
30
-
-
77949302911
-
Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism
-
Frigerio F, Brun T, Bartley C, Usardi A, Bosco D, et al. (2010) Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism. Diabetologia 53: 331-340.
-
(2010)
Diabetologia
, vol.53
, pp. 331-340
-
-
Frigerio, F.1
Brun, T.2
Bartley, C.3
Usardi, A.4
Bosco, D.5
-
31
-
-
1842844280
-
Identification of the human mitochondrial S-adenosylmethionine transporter: Bacterial expression, reconstitution, functional characterization and tissue distribution
-
Agrimi G, Di Noia MA, Marobbio CM, Fiermonte G, Lasorsa FM, et al. (2004) Identification of the human mitochondrial S-adenosylmethionine transporter: bacterial expression, reconstitution, functional characterization and tissue distribution. Biochem J 379: 183-190.
-
(2004)
Biochem J
, vol.379
, pp. 183-190
-
-
Agrimi, G.1
Di Noia, M.A.2
Marobbio, C.M.3
Fiermonte, G.4
Lasorsa, F.M.5
-
32
-
-
11244318158
-
The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells
-
Rubi B, del Arco A, Bartley C, Satrustegui J, Maechler P (2004) The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells. J Biol Chem 279: 55659-55666.
-
(2004)
J Biol Chem
, vol.279
, pp. 55659-55666
-
-
Rubi, B.1
Del Arco, A.2
Bartley, C.3
Satrustegui, J.4
Maechler, P.5
-
33
-
-
84874083265
-
neXtProt: Organizing Protein Knowledge in the Context of Human Proteome Projects
-
Gaudet P, Argoud-Puy G, Cusin I, Duek P, Evalet O, et al. (2013) neXtProt: Organizing Protein Knowledge in the Context of Human Proteome Projects. J Proteome Res 12: 293-298.
-
(2013)
J Proteome Res
, vol.12
, pp. 293-298
-
-
Gaudet, P.1
Argoud-Puy, G.2
Cusin, I.3
Duek, P.4
Evalet, O.5
-
34
-
-
38449101120
-
Integration of biological networks and gene expression data using Cytoscape
-
Cline MS, Smoot M, Cerami E, Kuchinsky A, Landys N, et al. (2007) Integration of biological networks and gene expression data using Cytoscape. Nat Protoc 2: 2366-2382.
-
(2007)
Nat Protoc
, vol.2
, pp. 2366-2382
-
-
Cline, M.S.1
Smoot, M.2
Cerami, E.3
Kuchinsky, A.4
Landys, N.5
-
35
-
-
33745116619
-
Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis
-
Karaskov E, Scott C, Zhang L, Teodoro T, Ravazzola M, et al. (2006) Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis. Endocrinology 147: 3398-3407.
-
(2006)
Endocrinology
, vol.147
, pp. 3398-3407
-
-
Karaskov, E.1
Scott, C.2
Zhang, L.3
Teodoro, T.4
Ravazzola, M.5
-
36
-
-
84855605795
-
Endoplasmic reticulum stress, obesity and diabetes
-
Cnop M, Foufelle F, Velloso LA (2012) Endoplasmic reticulum stress, obesity and diabetes. Trends Mol Med 18: 59-68.
-
(2012)
Trends Mol Med
, vol.18
, pp. 59-68
-
-
Cnop, M.1
Foufelle, F.2
Velloso, L.A.3
-
37
-
-
0036230225
-
Expression profiling of palmitate- and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic beta-cell function
-
Busch AK, Cordery D, Denyer GS, Biden TJ (2002) Expression profiling of palmitate- and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic beta-cell function. Diabetes 51: 977-987.
-
(2002)
Diabetes
, vol.51
, pp. 977-987
-
-
Busch, A.K.1
Cordery, D.2
Denyer, G.S.3
Biden, T.J.4
-
38
-
-
70350164165
-
Overexpression of the malate-aspartate NADH shuttle member Aralar1 in the clonal beta-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism
-
Lond
-
Bender K, Maechler P, McClenaghan NH, Flatt PR, Newsholme P (2009) Overexpression of the malate-aspartate NADH shuttle member Aralar1 in the clonal beta-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism. Clin Sci (Lond) 117: 321-330.
-
(2009)
Clin Sci
, vol.117
, pp. 321-330
-
-
Bender, K.1
Maechler, P.2
McClenaghan, N.H.3
Flatt, P.R.4
Newsholme, P.5
-
39
-
-
0027199057
-
Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1)
-
Brun T, Roche E, Kim KH, Prentki M (1993) Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1). J Biol Chem 268: 18905-18911.
-
(1993)
J Biol Chem
, vol.268
, pp. 18905-18911
-
-
Brun, T.1
Roche, E.2
Kim, K.H.3
Prentki, M.4
-
40
-
-
84858196776
-
Overcoming the spatial barriers of the stimulus secretion cascade in pancreatic beta-cells
-
Huypens PR, Huang M, Joseph JW (2012) Overcoming the spatial barriers of the stimulus secretion cascade in pancreatic beta-cells. Islets 4.
-
(2012)
Islets
, vol.4
-
-
Huypens, P.R.1
Huang, M.2
Joseph, J.W.3
-
41
-
-
59449084679
-
Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations
-
Bensellam M, Van Lommel L, Overbergh L, Schuit FC, Jonas JC (2009) Cluster analysis of rat pancreatic islet gene mRNA levels after culture in low-, intermediate- and high-glucose concentrations. Diabetologia 52: 463-476.
-
(2009)
Diabetologia
, vol.52
, pp. 463-476
-
-
Bensellam, M.1
Van Lommel, L.2
Overbergh, L.3
Schuit, F.C.4
Jonas, J.C.5
-
42
-
-
34447124165
-
MAFA controls genes implicated in insulin biosynthesis and secretion
-
Wang H, Brun T, Kataoka K, Sharma AJ, Wollheim CB (2007) MAFA controls genes implicated in insulin biosynthesis and secretion. Diabetologia 50: 348-358.
-
(2007)
Diabetologia
, vol.50
, pp. 348-358
-
-
Wang, H.1
Brun, T.2
Kataoka, K.3
Sharma, A.J.4
Wollheim, C.B.5
-
43
-
-
0035816695
-
Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation
-
Wang H, Maechler P, Ritz-Laser B, Hagenfeldt KA, Ishihara H, et al. (2001) Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation. J Biol Chem 276: 25279-25286.
-
(2001)
J Biol Chem
, vol.276
, pp. 25279-25286
-
-
Wang, H.1
Maechler, P.2
Ritz-Laser, B.3
Hagenfeldt, K.A.4
Ishihara, H.5
-
44
-
-
79953206276
-
Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism
-
Vetterli L, Brun T, Giovannoni L, Bosco D, Maechler P (2011) Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism. J Biol Chem 286: 6049-6060.
-
(2011)
J Biol Chem
, vol.286
, pp. 6049-6060
-
-
Vetterli, L.1
Brun, T.2
Giovannoni, L.3
Bosco, D.4
Maechler, P.5
-
45
-
-
80052083866
-
Resveratrol-activated SIRT1 in liver and pancreatic beta-cells: A Janus head looking to the same direction of metabolic homeostasis
-
Albany NY
-
Vetterli L, Maechler P (2011) Resveratrol-activated SIRT1 in liver and pancreatic beta-cells: a Janus head looking to the same direction of metabolic homeostasis. Aging (Albany NY) 3: 444-449.
-
(2011)
Aging
, vol.3
, pp. 444-449
-
-
Vetterli, L.1
Maechler, P.2
-
46
-
-
36349030394
-
Regulation of Insulin Secretion by SIRT4, a Mitochondrial ADP-ribosyltransferase
-
Ahuja N, Schwer B, Carobbio S, Waltregny D, North BJ, et al. (2007) Regulation of Insulin Secretion by SIRT4, a Mitochondrial ADP- ribosyltransferase. J Biol Chem 282: 33583-33592.
-
(2007)
J Biol Chem
, vol.282
, pp. 33583-33592
-
-
Ahuja, N.1
Schwer, B.2
Carobbio, S.3
Waltregny, D.4
North, B.J.5
-
47
-
-
84867189044
-
Delineation of glutamate pathways and secretory responses in pancreatic islets with beta-cell-specific abrogation of the glutamate dehydrogenase
-
Vetterli L, Carobbio S, Pournourmohammadi S, Martin-Del-Rio R, Skytt DM, et al. (2012) Delineation of glutamate pathways and secretory responses in pancreatic islets with beta-cell-specific abrogation of the glutamate dehydrogenase. Mol Biol Cell 23: 3851-3862.
-
(2012)
Mol Biol Cell
, vol.23
, pp. 3851-3862
-
-
Vetterli, L.1
Carobbio, S.2
Pournourmohammadi, S.3
Martin-Del-Rio, R.4
Skytt, D.M.5
-
48
-
-
46349091157
-
Tissue specificity of mitochondrial glutamate pathways and the control of metabolic homeostasis
-
Frigerio F, Casimir M, Carobbio S, Maechler P (2008) Tissue specificity of mitochondrial glutamate pathways and the control of metabolic homeostasis. Biochim Biophys Acta 1777: 965-972.
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 965-972
-
-
Frigerio, F.1
Casimir, M.2
Carobbio, S.3
Maechler, P.4
-
49
-
-
26244456414
-
ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity
-
Wang H, Kouri G, Wollheim CB (2005) ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity. J Cell Sci 118: 3905-3915.
-
(2005)
J Cell Sci
, vol.118
, pp. 3905-3915
-
-
Wang, H.1
Kouri, G.2
Wollheim, C.B.3
-
50
-
-
78649826295
-
High glucose induces dysfunction in insulin secretory cells by different pathways: A proteomic approach
-
Maris M, Ferreira GB, D'Hertog W, Cnop M, Waelkens E, et al. (2010) High glucose induces dysfunction in insulin secretory cells by different pathways: a proteomic approach. J Proteome Res 9: 6274-6287.
-
(2010)
J Proteome Res
, vol.9
, pp. 6274-6287
-
-
Maris, M.1
Ferreira, G.B.2
D'Hertog, W.3
Cnop, M.4
Waelkens, E.5
-
51
-
-
0031750277
-
Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression
-
Roche E, Farfari S, Witters LA, Assimacopoulos-Jeannet F, Thumelin S, et al. (1998) Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression. Diabetes 47: 1086-1094.
-
(1998)
Diabetes
, vol.47
, pp. 1086-1094
-
-
Roche, E.1
Farfari, S.2
Witters, L.A.3
Assimacopoulos-Jeannet, F.4
Thumelin, S.5
-
52
-
-
33646142778
-
Glucose-induced repression of PPARalpha gene expression in pancreatic beta-cells involves PP2A activation and AMPK inactivation
-
Ravnskjaer K, Boergesen M, Dalgaard LT, Mandrup S (2006) Glucose-induced repression of PPARalpha gene expression in pancreatic beta-cells involves PP2A activation and AMPK inactivation. J Mol Endocrinol 36: 289-299.
-
(2006)
J Mol Endocrinol
, vol.36
, pp. 289-299
-
-
Ravnskjaer, K.1
Boergesen, M.2
Dalgaard, L.T.3
Mandrup, S.4
-
53
-
-
73549091684
-
Early activation of the fatty acid metabolism pathway by chronic high glucose exposure in rat insulin secretory beta-cells
-
Coute Y, Brunner Y, Schvartz D, Hernandez C, Masselot A, et al. (2010) Early activation of the fatty acid metabolism pathway by chronic high glucose exposure in rat insulin secretory beta-cells. Proteomics 10: 59-71.
-
(2010)
Proteomics
, vol.10
, pp. 59-71
-
-
Coute, Y.1
Brunner, Y.2
Schvartz, D.3
Hernandez, C.4
Masselot, A.5
-
54
-
-
11144262144
-
Perspective: Emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion
-
MacDonald MJ, Fahien LA, Brown LJ, Hasan NM, Buss JD, et al. (2005) Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion. Am J Physiol Endocrinol Metab 288: E1-15.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
MacDonald, M.J.1
Fahien, L.A.2
Brown, L.J.3
Hasan, N.M.4
Buss, J.D.5
-
55
-
-
33751281446
-
The importance of redox shuttles to pancreatic beta-cell energy metabolism and function
-
Bender K, Newsholme P, Brennan L, Maechler P (2006) The importance of redox shuttles to pancreatic beta-cell energy metabolism and function. Biochem Soc Trans 34: 811-814.
-
(2006)
Biochem Soc Trans
, vol.34
, pp. 811-814
-
-
Bender, K.1
Newsholme, P.2
Brennan, L.3
Maechler, P.4
-
56
-
-
57349097780
-
Metabolic cycling in control of glucose-stimulated insulin secretion
-
Jensen MV, Joseph JW, Ronnebaum SM, Burgess SC, Sherry AD, et al. (2008) Metabolic cycling in control of glucose-stimulated insulin secretion. Am J Physiol Endocrinol Metab 295: E1287-1297.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
-
-
Jensen, M.V.1
Joseph, J.W.2
Ronnebaum, S.M.3
Burgess, S.C.4
Sherry, A.D.5
-
57
-
-
0034751632
-
The effect of chronic exposure to fatty acids on gene expression in clonal insulin-producing cells: Studies using high density oligonucleotide microarray
-
Xiao J, Gregersen S, Kruhoffer M, Pedersen SB, Orntoft TF, et al. (2001) The effect of chronic exposure to fatty acids on gene expression in clonal insulin-producing cells: studies using high density oligonucleotide microarray. Endocrinology 142: 4777-4784.
-
(2001)
Endocrinology
, vol.142
, pp. 4777-4784
-
-
Xiao, J.1
Gregersen, S.2
Kruhoffer, M.3
Pedersen, S.B.4
Orntoft, T.F.5
-
58
-
-
0028268936
-
Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
-
Zhou YP, Grill VE (1994) Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J Clin Invest 93: 870-876.
-
(1994)
J Clin Invest
, vol.93
, pp. 870-876
-
-
Zhou, Y.P.1
Grill, V.E.2
-
59
-
-
0842327999
-
Chronic effects of fatty acids on pancreatic beta-cell function: New insights from functional genomics
-
Biden TJ, Robinson D, Cordery D, Hughes WE, Busch AK (2004) Chronic effects of fatty acids on pancreatic beta-cell function: new insights from functional genomics. Diabetes 53 Suppl 1: S159-165.
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 1
-
-
Biden, T.J.1
Robinson, D.2
Cordery, D.3
Hughes, W.E.4
Busch, A.K.5
-
60
-
-
0026110135
-
Banting lecture 1990. Beta-cells in type II diabetes mellitus
-
Porte D, Jr. (1991) Banting lecture 1990. Beta-cells in type II diabetes mellitus. Diabetes 40: 166-180.
-
(1991)
Diabetes
, vol.40
, pp. 166-180
-
-
Porte Jr., D.1
-
61
-
-
80051796665
-
SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells
-
Koyama T, Kume S, Koya D, Araki S, Isshiki K, et al. (2011) SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells. Free Radic Biol Med 51: 1258-1267.
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 1258-1267
-
-
Koyama, T.1
Kume, S.2
Koya, D.3
Araki, S.4
Isshiki, K.5
-
62
-
-
80052291180
-
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
-
Jing E, Emanuelli B, Hirschey MD, Boucher J, Lee KY, et al. (2011) Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. Proc Natl Acad Sci U S A 108: 14608-14613.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 14608-14613
-
-
Jing, E.1
Emanuelli, B.2
Hirschey, M.D.3
Boucher, J.4
Lee, K.Y.5
-
63
-
-
84876502959
-
Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients
-
Caton PW, Richardson SJ, Kieswich J, Bugliani M, Holland ML, et al. (2013) Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients. Diabetologia 56: 1068-1077.
-
(2013)
Diabetologia
, vol.56
, pp. 1068-1077
-
-
Caton, P.W.1
Richardson, S.J.2
Kieswich, J.3
Bugliani, M.4
Holland, M.L.5
-
64
-
-
69949154243
-
Statins, fibrates and retinoic acid upregulate mitochondrial acylcarnitine carrier gene expression
-
Iacobazzi V, Convertini P, Infantino V, Scarcia P, Todisco S, et al. (2009) Statins, fibrates and retinoic acid upregulate mitochondrial acylcarnitine carrier gene expression. Biochem Biophys Res Commun 388: 643-647.
-
(2009)
Biochem Biophys Res Commun
, vol.388
, pp. 643-647
-
-
Iacobazzi, V.1
Convertini, P.2
Infantino, V.3
Scarcia, P.4
Todisco, S.5
|