A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes

Cell Metabolism

Volumn 13, Issue 1, 2011, Pages 80-91

  Koeck, Thomas ^a   Olsson, Anders H ^a   Nitert, Marloes Dekker ^a   Sharoyko, Vladimir V ^a   Ladenvall, Claes ^a   Kotova, Olga ^a   Reiling, Erwin ^b   Rönn, Tina ^a   Parikh, Hemang ^a   Taneera, Jalal ^a   Eriksson, Johan G ^c,d   Metodiev, Metodi D ^e   Larsson, Nils Göran ^e   Balhuizen, Alexander ^a   Luthman, Holger ^a   Stančáková, Alena ^f   Kuusisto, Johanna ^f   Laakso, Markku ^f   Poulsen, Pernille ^g,h   Vaag, Allan ^g   Groop, Leif ^a   Lyssenko, Valeriya ^a   Mulder, Hindrik ^a   Ling, Charlotte ^a   more..

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

^e MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

^f UNIVERSITY OF EASTERN FINLAND   (Finland)

^g STENO DIABETES CENTER   (Denmark)

^h NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; MESSENGER RNA; MITOCHONDRIAL TRANSCRIPTION FACTOR B; MITOCHONDRIAL TRANSCRIPTION FACTOR B1; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC RISK; GLUCOSE BLOOD LEVEL; HETEROZYGOTE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; MALE; MITOCHONDRION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RNA INTERFERENCE;

ANIMALS; BLOOD GLUCOSE; CELL LINE; DIABETES MELLITUS, TYPE 2; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION; GENE SILENCING; GENETIC LOCI; GENETIC VARIATION; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; MICE; MICE, TRANSGENIC; MIDDLE AGED; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; QUANTITATIVE TRAIT LOCI; RNA, MESSENGER; TRANSCRIPTION FACTORS;

MUS;

EID: 78650924382     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2010.12.007     Document Type: Article

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