NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion

Diabetes

Volumn 61, Issue 11, 2012, Pages 2842-2850

  Li, Ning ^a   Li, Bin ^a   Brun, Thierry ^a   Deffert Delbouille, Christine ^a   Mahiout, Zahia ^a   Daali, Youssef ^b   Ma, Xiao Juan ^a   Krause, Karl Heinz ^a   Maechler, Pierre ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; INSULIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATALYSIS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOSOME; GLUCOSE TOLERANCE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; LYSOSOME; MOUSE; NONHUMAN; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENE SILENCING; GLUCAGON-LIKE PEPTIDE 1; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; ISOENZYMES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NADPH OXIDASE; PROTEIN KINASE INHIBITORS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SECOND MESSENGER SYSTEMS; SECRETORY VESICLES; TISSUE CULTURE TECHNIQUES;

EID: 84865438872     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0009     Document Type: Article

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