Constructing kinetic models of metabolism at genome-scales: A review

Biotechnology Journal

Volumn 10, Issue 9, 2015, Pages 1345-1359

  Srinivasan, Shyam ^a   Cluett, William R ^a   Mahadevan, Radhakrishnan ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Approximate kinetic models; Constraint based models; Genome scale kinetic models; In silico modeling; Monte Carlo kinetic models

Indexed keywords

BIOLOGICAL SYSTEMS; GENES; KINETIC PARAMETERS; KINETIC THEORY; METABOLISM; METABOLITES; MONTE CARLO METHODS; PHYSIOLOGY; SIGNAL TRANSDUCTION; UNCERTAINTY ANALYSIS;

COMPUTATIONAL TRACTABILITY; CONSTRAINT-BASED MODELING; CONSTRAINT-BASED MODELS; IN-SILICO MODELS; KINETIC MODELS; METABOLITE CONCENTRATIONS; PARAMETER IDENTIFIABILITY; PARAMETER UNCERTAINTY;

PHYSIOLOGICAL MODELS;

COMPUTER MODEL; FEASIBILITY STUDY; GENOME; HUMAN; KINETIC PARAMETERS; KINETICS; METABOLIC FLUX ANALYSIS; METABOLIC REGULATION; METABOLISM; MONTE CARLO METHOD; NONHUMAN; PRIORITY JOURNAL; REVIEW; UNCERTAINTY; BIOLOGICAL MODEL; COMPUTER SIMULATION; ERYTHROCYTE;

COMPUTER SIMULATION; ERYTHROCYTES; GENOME; HUMANS; KINETICS; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL; MONTE CARLO METHOD;

EID: 84940557767     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201400522     Document Type: Review

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