Reducing the allowable kinetic space by constructing ensemble of dynamic models with the same steady-state flux

Metabolic Engineering

Volumn 13, Issue 1, 2011, Pages 60-75

  Tan, Yikun ^a   Lafontaine Rivera, Jimmy G ^a   Contador, Carolina A ^b   Asenjo, Juan A ^b   Liao, James C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

Dynamic model; Ensemble modeling; Steady state flux

Indexed keywords

CARBON METABOLISM; ENSEMBLE MODELING; GAINING INSIGHTS; HIGH-DIMENSIONAL; KINETIC RATES; METABOLITE PROFILES; MULTIPLE STEADY STATE; PARAMETER SPACES; PARAMETRIC SPACES; SOLUTION METHODS; STEADY STATE; STEADY-STATE FLUX;

ENZYME KINETICS; ENZYMES; ESCHERICHIA COLI; KINETIC PARAMETERS; METABOLISM;

DYNAMIC MODELS;

ACETIC ACID; CARBON; GLUCOSE; PYRUVIC ACID; SUCCINIC ACID;

ARTICLE; CARBON METABOLISM; ENSEMBLE MODELING; ENZYME KINETICS; ENZYME MECHANISM; ESCHERICHIA COLI; GLUCOSE TRANSPORT; MATHEMATICAL MODEL; METABOLITE; METHODOLOGY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; SCREENING; STEADY STATE; THERMODYNAMICS;

ALGORITHMS; CARBON; COMPUTER SIMULATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; KINETICS; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; SUCCINIC ACID;

ESCHERICHIA COLI;

EID: 78650571311     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2010.11.001     Document Type: Article

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