Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades

European Journal of Biochemistry

Volumn 267, Issue 6, 2000, Pages 1583-1588

  Kholodenko, Boris N ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Bistability; MAPK cascades; Protein phosphorylation; Signal transduction; Sustained oscillations

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN;

ARTICLE; CONTROLLED STUDY; ENZYME KINETICS; NEGATIVE FEEDBACK; OSCILLATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; STIMULUS;

ANIMALS; FEEDBACK; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; PERIODICITY; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 0034019315     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01197.x     Document Type: Article

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