메뉴 건너뛰기




Volumn 40, Issue 6, 2009, Pages 595-601

Ensemble modeling and related mathematical modeling of metabolic networks

Author keywords

Ensemble modeling; Kinetic modeling; Metabolic engineering; Metabolic modeling; Strain design; Systems biology

Indexed keywords

ENSEMBLE MODELING; KINETIC MODELING; METABOLIC ENGINEERING; METABOLIC MODELING; SYSTEMS BIOLOGY;

EID: 70349779362     PISSN: 18761070     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtice.2009.05.003     Document Type: Article
Times cited : (17)

References (67)
  • 2
    • 22844452835 scopus 로고    scopus 로고
    • Construction of Lycopene-overproducing E. coli Strains by Combining Systematic and Combinatorial Gene Knockout Targets
    • Alper H., Miyaoku K., and Stephanopoulos G. Construction of Lycopene-overproducing E. coli Strains by Combining Systematic and Combinatorial Gene Knockout Targets. Nat. Biotechnol. 23 (2005) 5
    • (2005) Nat. Biotechnol. , vol.23 , pp. 5
    • Alper, H.1    Miyaoku, K.2    Stephanopoulos, G.3
  • 3
    • 33745075591 scopus 로고    scopus 로고
    • Tools for Kinetic Modeling of Biochemical Networks
    • Alves R., Antunes F., and Salvador A. Tools for Kinetic Modeling of Biochemical Networks. Nat. Biotechnol. 24 (2006) 6
    • (2006) Nat. Biotechnol. , vol.24 , pp. 6
    • Alves, R.1    Antunes, F.2    Salvador, A.3
  • 4
    • 33745155105 scopus 로고    scopus 로고
    • Determination of Confidence Intervals of Metabolic Fluxes Estimated from Stable Isotope Measurements
    • Antoniewicz M.R., Kelleher J.K., and Stephanopoulos G. Determination of Confidence Intervals of Metabolic Fluxes Estimated from Stable Isotope Measurements. Metab. Eng. 8 (2006) 4
    • (2006) Metab. Eng. , vol.8 , pp. 4
    • Antoniewicz, M.R.1    Kelleher, J.K.2    Stephanopoulos, G.3
  • 5
    • 0036286631 scopus 로고    scopus 로고
    • Energy Balance for Analysis of Complex Metabolic Networks
    • Beard D.A., Liang S.D., and Qian H. Energy Balance for Analysis of Complex Metabolic Networks. Biophys. J. 83 (2002) 1
    • (2002) Biophys. J. , vol.83 , pp. 1
    • Beard, D.A.1    Liang, S.D.2    Qian, H.3
  • 6
    • 58149185126 scopus 로고    scopus 로고
    • BRENDA, AMENDA and FRENDA the Enzyme Information System: New Content and Tools in 2009
    • (Database issue)
    • Chang A., Scheer M., Grote A., Schomburg I., and Schomburg D. BRENDA, AMENDA and FRENDA the Enzyme Information System: New Content and Tools in 2009. Nucleic Acids Res. 37 (2009) D558 (Database issue)
    • (2009) Nucleic Acids Res. , vol.37
    • Chang, A.1    Scheer, M.2    Grote, A.3    Schomburg, I.4    Schomburg, D.5
  • 7
    • 0027426767 scopus 로고
    • Control of Gluconeogenic Growth by pps and pck in Escherichia coli
    • Chao Y.P., Patnaik R., Roof W.D., Young R.F., and Liao J.C. Control of Gluconeogenic Growth by pps and pck in Escherichia coli. J. Bacteriol. 175 (1993) 21
    • (1993) J. Bacteriol. , vol.175 , pp. 21
    • Chao, Y.P.1    Patnaik, R.2    Roof, W.D.3    Young, R.F.4    Liao, J.C.5
  • 8
    • 20744452513 scopus 로고    scopus 로고
    • A New Measure of the Robustness of Biochemical Networks
    • Chen B.S., Wang Y.C., Wu W.S., and Li W.H. A New Measure of the Robustness of Biochemical Networks. Bioinformatics 21 (2005) 11
    • (2005) Bioinformatics , vol.21 , pp. 11
    • Chen, B.S.1    Wang, Y.C.2    Wu, W.S.3    Li, W.H.4
  • 12
    • 2942579562 scopus 로고    scopus 로고
    • Metabolic Flux Balance Analysis and the in silico Analysis of Escherichia coli K-12 Gene Deletions
    • Edwards J.S., and Palsson B.O. Metabolic Flux Balance Analysis and the in silico Analysis of Escherichia coli K-12 Gene Deletions. BMC Bioinformatics 1 (2000) 1
    • (2000) BMC Bioinformatics , vol.1 , pp. 1
    • Edwards, J.S.1    Palsson, B.O.2
  • 13
    • 22144446710 scopus 로고    scopus 로고
    • Controllability of Non-linear Biochemical Systems
    • Ervadi-Radhakrishnan A., and Voit E.O. Controllability of Non-linear Biochemical Systems. Math. Biosci. 196 (2005) 1
    • (2005) Math. Biosci. , vol.196 , pp. 1
    • Ervadi-Radhakrishnan, A.1    Voit, E.O.2
  • 14
    • 0035128694 scopus 로고    scopus 로고
    • Precursor Balancing for Metabolic Engineering of Lycopene Production in Escherichia coli
    • Farmer W.R., and Liao J.C. Precursor Balancing for Metabolic Engineering of Lycopene Production in Escherichia coli. Biotechnol. Prog. 17 (2001) 1
    • (2001) Biotechnol. Prog. , vol.17 , pp. 1
    • Farmer, W.R.1    Liao, J.C.2
  • 15
    • 0026802334 scopus 로고
    • Metabolic Control Analysis: A Survey of Its Theoretical and Experimental Development
    • Fell D.A. Metabolic Control Analysis: A Survey of Its Theoretical and Experimental Development. Biochem. J. 286 (1992) 313
    • (1992) Biochem. J. , vol.286 , pp. 313
    • Fell, D.A.1
  • 18
    • 33646835242 scopus 로고    scopus 로고
    • An Effective Method to Increase Solvability in Biochemical Systems Using S-system
    • Hasegawa T., and Yoshimura J. An Effective Method to Increase Solvability in Biochemical Systems Using S-system. Math. Biosci. 201 (2006) 1
    • (2006) Math. Biosci. , vol.201 , pp. 1
    • Hasegawa, T.1    Yoshimura, J.2
  • 20
    • 0032600734 scopus 로고    scopus 로고
    • Nonlinear Metabolic Control Analysis
    • Hatzimanikatis V. Nonlinear Metabolic Control Analysis. Metab. Eng. 1 (1999) 1
    • (1999) Metab. Eng. , vol.1 , pp. 1
    • Hatzimanikatis, V.1
  • 21
    • 6044221509 scopus 로고    scopus 로고
    • Metabolic Flux Control Analysis of Branch Points: An Improved Approach to Obtain Flux Control Coefficients from Large Perturbation Data
    • Heijnen J.J., van Gulik W.M., Shimizu H., and Stephanopoulos G. Metabolic Flux Control Analysis of Branch Points: An Improved Approach to Obtain Flux Control Coefficients from Large Perturbation Data. Metab. Eng. 6 (2004) 4
    • (2004) Metab. Eng. , vol.6 , pp. 4
    • Heijnen, J.J.1    van Gulik, W.M.2    Shimizu, H.3    Stephanopoulos, G.4
  • 22
    • 25144492110 scopus 로고    scopus 로고
    • Approximative Kinetic Formats Used in Metabolic Network Modeling
    • Heijnen J.J. Approximative Kinetic Formats Used in Metabolic Network Modeling. Biotechnol. Bioeng. 91 (2005) 5
    • (2005) Biotechnol. Bioeng. , vol.91 , pp. 5
    • Heijnen, J.J.1
  • 27
  • 28
    • 0021531929 scopus 로고
    • Cybernetic Modeling of Microbial Growth on Multiple Substrates
    • Kompala D.S., Ramkrishna D., and Tsao G.T. Cybernetic Modeling of Microbial Growth on Multiple Substrates. Biotechnol. Bioeng. 26 (1984) 11
    • (1984) Biotechnol. Bioeng. , vol.26 , pp. 11
    • Kompala, D.S.1    Ramkrishna, D.2    Tsao, G.T.3
  • 29
    • 33845238737 scopus 로고    scopus 로고
    • Systematic Assignment of Thermodynamic Constraints in Metabolic Network Models
    • Kummel A., Panke S., and Heinemann M. Systematic Assignment of Thermodynamic Constraints in Metabolic Network Models. BMC Bioinformatics 7 (2006) 512
    • (2006) BMC Bioinformatics , vol.7 , pp. 512
    • Kummel, A.1    Panke, S.2    Heinemann, M.3
  • 30
    • 85142187064 scopus 로고    scopus 로고
    • WebCell: A Web-based Environment for Kinetic Modeling and Dynamic Simulation of Cellular Networks
    • Lee D.Y., Yun C., Cho A., Hou B.K., Park S., and Lee S.Y. WebCell: A Web-based Environment for Kinetic Modeling and Dynamic Simulation of Cellular Networks. Bioinformatics 22 (2006) 9
    • (2006) Bioinformatics , vol.22 , pp. 9
    • Lee, D.Y.1    Yun, C.2    Cho, A.3    Hou, B.K.4    Park, S.5    Lee, S.Y.6
  • 31
    • 0027601708 scopus 로고
    • Advances in Metabolic Control Analysis
    • Liao J.C., and Delgado J. Advances in Metabolic Control Analysis. Biotechnol. Prog. 9 (1993) 3
    • (1993) Biotechnol. Prog. , vol.9 , pp. 3
    • Liao, J.C.1    Delgado, J.2
  • 32
    • 0030571222 scopus 로고    scopus 로고
    • Pathway Analysis, Engineering, and Physiological Considerations for Redirecting Central Metabolism
    • Liao J.C., Hou S.Y., and Chao Y.P. Pathway Analysis, Engineering, and Physiological Considerations for Redirecting Central Metabolism. Biotechnol. Bioeng. 52 (1996) 1
    • (1996) Biotechnol. Bioeng. , vol.52 , pp. 1
    • Liao, J.C.1    Hou, S.Y.2    Chao, Y.P.3
  • 33
    • 33846617808 scopus 로고    scopus 로고
    • Bringing Metabolic Networks to Life: Convenience Rate Law and Thermodynamic Constraints
    • Liebermeister W., and Klipp E. Bringing Metabolic Networks to Life: Convenience Rate Law and Thermodynamic Constraints. Theor. Biol. Med. Model. 3 (2006) 42
    • (2006) Theor. Biol. Med. Model. , vol.3 , pp. 42
    • Liebermeister, W.1    Klipp, E.2
  • 34
    • 0032406131 scopus 로고    scopus 로고
    • Non-linear Optimization of Biochemical Pathways: Applications to Metabolic Engineering and Parameter Estimation
    • Mendes P., and Kell D. Non-linear Optimization of Biochemical Pathways: Applications to Metabolic Engineering and Parameter Estimation. Bioinformatics 14 (1998) 10
    • (1998) Bioinformatics , vol.14 , pp. 10
    • Mendes, P.1    Kell, D.2
  • 35
    • 0347762731 scopus 로고    scopus 로고
    • Exploring the Overproduction of Amino Acids Using the Bilevel Optimization Framework OptKnock
    • Pharkya P., Burgard A.P., and Maranas C.D. Exploring the Overproduction of Amino Acids Using the Bilevel Optimization Framework OptKnock. Biotechnol. Bioeng. 84 (2003) 7
    • (2003) Biotechnol. Bioeng. , vol.84 , pp. 7
    • Pharkya, P.1    Burgard, A.P.2    Maranas, C.D.3
  • 36
    • 8744224466 scopus 로고    scopus 로고
    • OptStrain: A Computational Framework for Redesign of Microbial Production Systems
    • Pharkya P., Burgard A.P., and Maranas C.D. OptStrain: A Computational Framework for Redesign of Microbial Production Systems. Genome Res. 14 (2004) 11
    • (2004) Genome Res. , vol.14 , pp. 11
    • Pharkya, P.1    Burgard, A.P.2    Maranas, C.D.3
  • 37
    • 29544436058 scopus 로고    scopus 로고
    • An Optimization Framework for Identifying Reaction Activation/Inhibition or Elimination Candidates for Overproduction in Microbial Systems
    • Pharkya P., and Maranas C.D. An Optimization Framework for Identifying Reaction Activation/Inhibition or Elimination Candidates for Overproduction in Microbial Systems. Metab. Eng. 8 (2006) 1
    • (2006) Metab. Eng. , vol.8 , pp. 1
    • Pharkya, P.1    Maranas, C.D.2
  • 38
    • 33646364037 scopus 로고    scopus 로고
    • Identification of Metabolic System Parameters Using Global Optimization Methods
    • Polisetty P.K., Voit E.O., and Gatzke E.P. Identification of Metabolic System Parameters Using Global Optimization Methods. Theor. Biol. Med. Model. 3 (2006)
    • (2006) Theor. Biol. Med. Model. , vol.3
    • Polisetty, P.K.1    Voit, E.O.2    Gatzke, E.P.3
  • 39
    • 0023709196 scopus 로고
    • Metabolic Control Theory: A Structural Approach
    • Reder C. Metabolic Control Theory: A Structural Approach. J. Theor. Biol. 135 (1988) 2
    • (1988) J. Theor. Biol. , vol.135 , pp. 2
    • Reder, C.1
  • 40
    • 34547683486 scopus 로고    scopus 로고
    • Experimental and Mathematical Approaches to Modeling Plant Metabolic Networks
    • Rios-Estepa R., and Lange B.M. Experimental and Mathematical Approaches to Modeling Plant Metabolic Networks. Phytochemistry 68 (2007) 16
    • (2007) Phytochemistry , vol.68 , pp. 16
    • Rios-Estepa, R.1    Lange, B.M.2
  • 41
    • 0027178664 scopus 로고
    • SCAMP: A General-Purpose Simulator and Metabolic Control Analysis Program
    • Sauro H.M. SCAMP: A General-Purpose Simulator and Metabolic Control Analysis Program. Comput. Appl. Biosci. 9 (1993) 4
    • (1993) Comput. Appl. Biosci. , vol.9 , pp. 4
    • Sauro, H.M.1
  • 42
    • 0014649230 scopus 로고
    • Biochemical Systems Analysis. I. Some Mathematical Properties of the Rate Law for the Component Enzyme Reactions
    • Savageau M.A. Biochemical Systems Analysis. I. Some Mathematical Properties of the Rate Law for the Component Enzyme Reactions. J. Theor. Biol. 25 (1969) 365
    • (1969) J. Theor. Biol. , vol.25 , pp. 365
    • Savageau, M.A.1
  • 43
    • 0025768289 scopus 로고
    • Biochemical Systems Theory: Operational Differences among Variant Representations and Their Significance
    • Savageau M.A. Biochemical Systems Theory: Operational Differences among Variant Representations and Their Significance. J. Theor. Biol. 151 (1991) 4
    • (1991) J. Theor. Biol. , vol.151 , pp. 4
    • Savageau, M.A.1
  • 44
    • 0034447725 scopus 로고    scopus 로고
    • Combining Pathway Analysis with Flux Balance Analysis for the Comprehensive Study of Metabolic Systems
    • Schilling C.H., Edwards J.S., Letscher D., and Palsson B.O. Combining Pathway Analysis with Flux Balance Analysis for the Comprehensive Study of Metabolic Systems. Biotechnol. Bioeng. 71 (2000) 4
    • (2000) Biotechnol. Bioeng. , vol.71 , pp. 4
    • Schilling, C.H.1    Edwards, J.S.2    Letscher, D.3    Palsson, B.O.4
  • 45
    • 0033156024 scopus 로고    scopus 로고
    • Use and Limitations of Modular Metabolic Control Analysis in Medicine and Biotechnology
    • Schuster S. Use and Limitations of Modular Metabolic Control Analysis in Medicine and Biotechnology. Metab. Eng. 1 (1999) 3
    • (1999) Metab. Eng. , vol.1 , pp. 3
    • Schuster, S.1
  • 46
    • 0033080396 scopus 로고    scopus 로고
    • Detection of Elementary Flux Modes in Biochemical Networks: A Promising Tool for Pathway Analysis and Metabolic Engineering
    • Schuster S., Dandekar T., and Fell D.A. Detection of Elementary Flux Modes in Biochemical Networks: A Promising Tool for Pathway Analysis and Metabolic Engineering. Trends Biotechnol. 17 (1999) 2
    • (1999) Trends Biotechnol. , vol.17 , pp. 2
    • Schuster, S.1    Dandekar, T.2    Fell, D.A.3
  • 47
    • 0037069467 scopus 로고    scopus 로고
    • Analysis of Optimality in Natural and Perturbed Metabolic Networks
    • Segre D., Vitkup D., and Church G.M. Analysis of Optimality in Natural and Perturbed Metabolic Networks. Proc. Natl. Acad. Sci. USA 99 (2002) 23
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 23
    • Segre, D.1    Vitkup, D.2    Church, G.M.3
  • 49
    • 0037461036 scopus 로고    scopus 로고
    • Cellerator: Extending a Computer Algebra System to Include Biochemical Arrows for Signal Transduction Simulations
    • Shapiro B.E., Levchenko A., Meyerowitz E.M., Wold B.J., and Mjolsness E.D. Cellerator: Extending a Computer Algebra System to Include Biochemical Arrows for Signal Transduction Simulations. Bioinformatics 19 (2003) 5
    • (2003) Bioinformatics , vol.19 , pp. 5
    • Shapiro, B.E.1    Levchenko, A.2    Meyerowitz, E.M.3    Wold, B.J.4    Mjolsness, E.D.5
  • 50
    • 19644386033 scopus 로고    scopus 로고
    • Regulatory On/Off Minimization of Metabolic Flux Changes after Genetic Perturbations
    • Shlomi T., Berkman O., and Ruppin E. Regulatory On/Off Minimization of Metabolic Flux Changes after Genetic Perturbations. Proc. Natl. Acad. Sci. USA 102 (2005) 21
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 21
    • Shlomi, T.1    Berkman, O.2    Ruppin, E.3
  • 51
    • 12244298643 scopus 로고    scopus 로고
    • Quantification of Compartmented Metabolic Fluxes in Developing Soybean Embryos by Employing Biosynthetically Directed Fractional (13)C Labeling, Two-dimensional [(13)C, (1)H] Nuclear Magnetic Resonance, and Comprehensive Isotopomer Balancing
    • Sriram G., Fulton D.B., Iyer V.V., Peterson J.M., Zhou R., Westgate M.E., Spalding M.H., and Shanks J.V. Quantification of Compartmented Metabolic Fluxes in Developing Soybean Embryos by Employing Biosynthetically Directed Fractional (13)C Labeling, Two-dimensional [(13)C, (1)H] Nuclear Magnetic Resonance, and Comprehensive Isotopomer Balancing. Plant Physiol. 136 (2004) 2
    • (2004) Plant Physiol. , vol.136 , pp. 2
    • Sriram, G.1    Fulton, D.B.2    Iyer, V.V.3    Peterson, J.M.4    Zhou, R.5    Westgate, M.E.6    Spalding, M.H.7    Shanks, J.V.8
  • 52
    • 2442498572 scopus 로고    scopus 로고
    • Improvements in Metabolic Flux Analysis Using Carbon Bond Labeling Experiments: Bondomer Balancing and Boolean Function Mapping
    • Sriram G., and Shanks J.V. Improvements in Metabolic Flux Analysis Using Carbon Bond Labeling Experiments: Bondomer Balancing and Boolean Function Mapping. Metab. Eng. 6 (2004) 2
    • (2004) Metab. Eng. , vol.6 , pp. 2
    • Sriram, G.1    Shanks, J.V.2
  • 53
    • 0345863934 scopus 로고    scopus 로고
    • The CyberCell Database (CCDB): A Comprehensive, Self-Updating, Relational Database to Coordinate and Facilitate in silico Modeling of Escherichia coli
    • (Database issue)
    • Sundararaj S., Guo A., Habibi-Nazhad B., Rouani M., Stothard P., Ellison M., and Wishart D.S. The CyberCell Database (CCDB): A Comprehensive, Self-Updating, Relational Database to Coordinate and Facilitate in silico Modeling of Escherichia coli. Nucleic Acids Res. 32 (2004) D293 (Database issue)
    • (2004) Nucleic Acids Res. , vol.32
    • Sundararaj, S.1    Guo, A.2    Habibi-Nazhad, B.3    Rouani, M.4    Stothard, P.5    Ellison, M.6    Wishart, D.S.7
  • 54
    • 58749106454 scopus 로고    scopus 로고
    • Ensemble Modeling of Metabolic Networks
    • Tran L.M., Rizk M.L., and Liao J.C. Ensemble Modeling of Metabolic Networks. Biophys. J. 95 (2008) 12
    • (2008) Biophys. J. , vol.95 , pp. 12
    • Tran, L.M.1    Rizk, M.L.2    Liao, J.C.3
  • 56
    • 0033005128 scopus 로고    scopus 로고
    • Metabolic Engineering from a Cybernetic Perspective. 1. Theoretical Preliminaries
    • Varner J., and Ramkrishna D. Metabolic Engineering from a Cybernetic Perspective. 1. Theoretical Preliminaries. Biotechnol. Prog. 15 (1999) 3
    • (1999) Biotechnol. Prog. , vol.15 , pp. 3
    • Varner, J.1    Ramkrishna, D.2
  • 57
    • 0036526636 scopus 로고    scopus 로고
    • The Mathematics of Metabolic Control Analysis Revisited
    • Visser D., and Heijnen J.J. The Mathematics of Metabolic Control Analysis Revisited. Metab. Eng. 4 (2002) 2
    • (2002) Metab. Eng. , vol.4 , pp. 2
    • Visser, D.1    Heijnen, J.J.2
  • 58
    • 0141684666 scopus 로고    scopus 로고
    • Dynamic Simulation and Metabolic Re-Design of a Branched Pathway Using Linlog Kinetics
    • Visser D., and Heijnen J.J. Dynamic Simulation and Metabolic Re-Design of a Branched Pathway Using Linlog Kinetics. Metab. Eng. 5 (2003) 3
    • (2003) Metab. Eng. , vol.5 , pp. 3
    • Visser, D.1    Heijnen, J.J.2
  • 59
    • 6044260198 scopus 로고    scopus 로고
    • Optimal Re-Design of Primary Metabolism in Escherichia coli Using Linlog Kinetics
    • Visser D., Schmid J.W., Mauch K., Reuss M., and Heijnen J.J. Optimal Re-Design of Primary Metabolism in Escherichia coli Using Linlog Kinetics. Metab. Eng. 6 (2004) 4
    • (2004) Metab. Eng. , vol.6 , pp. 4
    • Visser, D.1    Schmid, J.W.2    Mauch, K.3    Reuss, M.4    Heijnen, J.J.5
  • 60
    • 33845475855 scopus 로고    scopus 로고
    • A Computational Procedure for Optimal Engineering Interventions Using Kinetic Models of Metabolism
    • Vital-Lopez F.G., Armaou A., Nikolaev E.V., and Maranas C.D. A Computational Procedure for Optimal Engineering Interventions Using Kinetic Models of Metabolism. Biotechnol. Prog. 22 (2006) 6
    • (2006) Biotechnol. Prog. , vol.22 , pp. 6
    • Vital-Lopez, F.G.1    Armaou, A.2    Nikolaev, E.V.3    Maranas, C.D.4
  • 61
    • 0036591839 scopus 로고    scopus 로고
    • Metabolic Modeling: A Tool of Drug Discovery in the Post-genomic Era
    • Voit E.O. Metabolic Modeling: A Tool of Drug Discovery in the Post-genomic Era. Drug Discov. Today 7 (2002) 11
    • (2002) Drug Discov. Today , vol.7 , pp. 11
    • Voit, E.O.1
  • 62
    • 10044224601 scopus 로고    scopus 로고
    • Metabolic Control Analysis under Uncertainty: Framework Development and Case Studies
    • Wang L., Birol I., and Hatzimanikatis V. Metabolic Control Analysis under Uncertainty: Framework Development and Case Studies. Biophys. J. 87 (2004) 6
    • (2004) Biophys. J. , vol.87 , pp. 6
    • Wang, L.1    Birol, I.2    Hatzimanikatis, V.3
  • 63
    • 33644817094 scopus 로고    scopus 로고
    • Metabolic Engineering under Uncertainty. II. Analysis of Yeast Metabolism
    • Wang L., and Hatzimanikatis V. Metabolic Engineering under Uncertainty. II. Analysis of Yeast Metabolism. Metab. Eng. 8 (2006) 2
    • (2006) Metab. Eng. , vol.8 , pp. 2
    • Wang, L.1    Hatzimanikatis, V.2
  • 64
    • 36348980985 scopus 로고    scopus 로고
    • Current Progress in Computational Metabolomics
    • Wishart D.S. Current Progress in Computational Metabolomics. Brief Bioinform. 8 (2007) 5
    • (2007) Brief Bioinform. , vol.8 , pp. 5
    • Wishart, D.S.1
  • 65
    • 6044229632 scopus 로고    scopus 로고
    • Metabolic Network Simulation Using Logical Loop Algorithm and Jacobian Matrix
    • Yang T.H., Wittmann C., and Heinzle E.E. Metabolic Network Simulation Using Logical Loop Algorithm and Jacobian Matrix. Metab. Eng. 6 (2004) 4
    • (2004) Metab. Eng. , vol.6 , pp. 4
    • Yang, T.H.1    Wittmann, C.2    Heinzle, E.E.3
  • 66
    • 16344378267 scopus 로고    scopus 로고
    • Theoretical Aspects of 13C Metabolic Flux Analysis with Sole Quantification of Carbon Dioxide Labeling
    • Yang T.H., Heinzle E., and Wittmann C. Theoretical Aspects of 13C Metabolic Flux Analysis with Sole Quantification of Carbon Dioxide Labeling. Comput. Biol. Chem. 29 (2005) 2
    • (2005) Comput. Biol. Chem. , vol.29 , pp. 2
    • Yang, T.H.1    Heinzle, E.2    Wittmann, C.3
  • 67
    • 0642305408 scopus 로고    scopus 로고
    • Metabolic Engineering: Advances in Modeling and Intervention in Health and Disease
    • Yarmush M.L., and Banta S. Metabolic Engineering: Advances in Modeling and Intervention in Health and Disease. Annu. Rev. Biomed. Eng. 5 (2003) 349
    • (2003) Annu. Rev. Biomed. Eng. , vol.5 , pp. 349
    • Yarmush, M.L.1    Banta, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.