-
1
-
-
57649167477
-
Necroptosis: A specialized pathway of programmed necrosis
-
1:CAS:528:DC%2BD1MXisFOqtQ%3D%3D 19109884
-
Galluzzi L, Kroemer G (2008) Necroptosis: a specialized pathway of programmed necrosis. Cell 135:1161-1163
-
(2008)
Cell
, vol.135
, pp. 1161-1163
-
-
Galluzzi, L.1
Kroemer, G.2
-
2
-
-
84939986310
-
Essential versus accessory aspects of cell death: Recommendations of the NCCD 2015
-
Galluzzi L, Bravo-San Pedro JM, Vitale I et al (2014) Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death Differ. doi: 10.1038/cdd.2014.137
-
(2014)
Cell Death Differ
-
-
Galluzzi, L.1
Bravo-San Pedro, J.M.2
Vitale, I.3
-
3
-
-
81055144784
-
Autophagy: Renovation of cells and tissues
-
1:CAS:528:DC%2BC3MXhsVKgsLnN 22078875
-
Mizushima N, Komatsu M (2011) Autophagy: renovation of cells and tissues. Cell 147:728-741
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
4
-
-
84887497763
-
2+ in quality control: An unresolved riddle critical to autophagy and mitophagy
-
1:CAS:528:DC%2BC2cXhtVyiurzK 24121708
-
2+ in quality control: an unresolved riddle critical to autophagy and mitophagy. Autophagy 9:1710-1719
-
(2013)
Autophagy
, vol.9
, pp. 1710-1719
-
-
East, D.A.1
Campanella, M.2
-
5
-
-
84879381221
-
Role of the crosstalk between autophagy and apoptosis in cancer
-
3687500 23840208
-
Su M, Mei Y, Sinha S (2013) Role of the crosstalk between autophagy and apoptosis in cancer. J Oncol 2013:102735
-
(2013)
J Oncol
, vol.2013
, pp. 102735
-
-
Su, M.1
Mei, Y.2
Sinha, S.3
-
6
-
-
84892569830
-
An overview of autophagy: Morphology, mechanism, and regulation
-
3894687 1:CAS:528:DC%2BC2cXnt1emsw%3D%3D 23725295
-
Parzych KR, Klionsky DJ (2014) An overview of autophagy: morphology, mechanism, and regulation. Antioxid Redox Signal 20:460-473
-
(2014)
Antioxid Redox Signal
, vol.20
, pp. 460-473
-
-
Parzych, K.R.1
Klionsky, D.J.2
-
7
-
-
77956404377
-
Eaten alive: A history of macroautophagy
-
3616322 1:CAS:528:DC%2BC3cXhtFSju7zE 20811353
-
Yang Z, Klionsky DJ (2010) Eaten alive: a history of macroautophagy. Nat Cell Biol 12:814-822
-
(2010)
Nat Cell Biol
, vol.12
, pp. 814-822
-
-
Yang, Z.1
Klionsky, D.J.2
-
8
-
-
77949328788
-
Chaperone-mediated autophagy: Selectivity pays off
-
2831144 1:CAS:528:DC%2BC3cXis1ShtbY%3D 19857975
-
Cuervo AM (2010) Chaperone-mediated autophagy: selectivity pays off. Trends Endocrinol Metab 21:142-150
-
(2010)
Trends Endocrinol Metab
, vol.21
, pp. 142-150
-
-
Cuervo, A.M.1
-
9
-
-
77950462712
-
Where do they come from? Insights into autophagosome formation
-
1:CAS:528:DC%2BC3cXjs12nu78%3D 20188731
-
Hamasaki M, Yoshimori T (2010) Where do they come from? Insights into autophagosome formation. FEBS Lett 584:1296-1301
-
(2010)
FEBS Lett
, vol.584
, pp. 1296-1301
-
-
Hamasaki, M.1
Yoshimori, T.2
-
10
-
-
84890803688
-
Autophagy and apoptosis dysfunction in neurodegenerative disorders
-
1:CAS:528:DC%2BC3sXhvFyqsbbF 24211851
-
Ghavami S, Shojaei S, Yeganeh B et al (2014) Autophagy and apoptosis dysfunction in neurodegenerative disorders. Prog Neurobiol 112:24-49
-
(2014)
Prog Neurobiol
, vol.112
, pp. 24-49
-
-
Ghavami, S.1
Shojaei, S.2
Yeganeh, B.3
-
11
-
-
50249084987
-
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
-
2518708 1:CAS:528:DC%2BD1cXhtV2rurzK 18725538
-
Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, Griffiths G, Ktistakis NT (2008) Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 182:685-701
-
(2008)
J Cell Biol
, vol.182
, pp. 685-701
-
-
Axe, E.L.1
Walker, S.A.2
Manifava, M.3
Chandra, P.4
Roderick, H.L.5
Habermann, A.6
Griffiths, G.7
Ktistakis, N.T.8
-
12
-
-
71649087199
-
A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation
-
1:CAS:528:DC%2BD1MXhsV2gsLnE 19898463
-
Hayashi-Nishino M, Fujita N, Noda T, Yamaguchi A, Yoshimori T, Yamamoto A (2009) A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation. Nat Cell Biol 11:1433-1437
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1433-1437
-
-
Hayashi-Nishino, M.1
Fujita, N.2
Noda, T.3
Yamaguchi, A.4
Yoshimori, T.5
Yamamoto, A.6
-
13
-
-
77952495224
-
Mitochondria supply membranes for autophagosome biogenesis during starvation
-
3059894 1:CAS:528:DC%2BC3cXms1egsr8%3D 20478256
-
Hailey DW, Rambold AS, Satpute-Krishnan P, Mitra K, Sougrat R, Kim PK, Lippincott-Schwartz J (2010) Mitochondria supply membranes for autophagosome biogenesis during starvation. Cell 141:656-667
-
(2010)
Cell
, vol.141
, pp. 656-667
-
-
Hailey, D.W.1
Rambold, A.S.2
Satpute-Krishnan, P.3
Mitra, K.4
Sougrat, R.5
Kim, P.K.6
Lippincott-Schwartz, J.7
-
14
-
-
84875365804
-
Autophagosomes form at ER-mitochondria contact sites
-
1:CAS:528:DC%2BC3sXktlGhtr4%3D 23455425
-
Hamasaki M, Furuta N, Matsuda A et al (2013) Autophagosomes form at ER-mitochondria contact sites. Nature 495:389-393
-
(2013)
Nature
, vol.495
, pp. 389-393
-
-
Hamasaki, M.1
Furuta, N.2
Matsuda, A.3
-
15
-
-
78649281871
-
Plasma membrane helps autophagosomes grow
-
3039720 1:CAS:528:DC%2BC3cXhs1WltrnP 20861674
-
Ravikumar B, Moreau K, Rubinsztein DC (2010) Plasma membrane helps autophagosomes grow. Autophagy 6:1184-1186
-
(2010)
Autophagy
, vol.6
, pp. 1184-1186
-
-
Ravikumar, B.1
Moreau, K.2
Rubinsztein, D.C.3
-
16
-
-
84864991509
-
Atg9 vesicles are an important membrane source during early steps of autophagosome formation
-
3410421 1:CAS:528:DC%2BC38XhtFaisLbO 22826123
-
Yamamoto H, Kakuta S, Watanabe TM, Kitamura A, Sekito T, Kondo-Kakuta C, Ichikawa R, Kinjo M, Ohsumi Y (2012) Atg9 vesicles are an important membrane source during early steps of autophagosome formation. J Cell Biol 198:219-233
-
(2012)
J Cell Biol
, vol.198
, pp. 219-233
-
-
Yamamoto, H.1
Kakuta, S.2
Watanabe, T.M.3
Kitamura, A.4
Sekito, T.5
Kondo-Kakuta, C.6
Ichikawa, R.7
Kinjo, M.8
Ohsumi, Y.9
-
17
-
-
78649338141
-
Autophagy and the integrated stress response
-
3127250 1:CAS:528:DC%2BC3cXhtlCjtr%2FM 20965422
-
Kroemer G, Mariño G, Levine B (2010) Autophagy and the integrated stress response. Mol Cell 40:280-293
-
(2010)
Mol Cell
, vol.40
, pp. 280-293
-
-
Kroemer, G.1
Mariño, G.2
Levine, B.3
-
18
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
3404883 1:CAS:528:DC%2BC38Xht1art7zK 22966490
-
Klionsky DJ, Abdalla FC, Abeliovich H et al (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8:445-544
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
Abdalla, F.C.2
Abeliovich, H.3
-
19
-
-
77950994646
-
Autophagy: Cellular and molecular mechanisms
-
2990190 1:CAS:528:DC%2BC3cXntFyjs7g%3D 20225336
-
Glick D, Barth S, Macleod KF (2010) Autophagy: cellular and molecular mechanisms. J Pathol 221:3-12
-
(2010)
J Pathol
, vol.221
, pp. 3-12
-
-
Glick, D.1
Barth, S.2
MacLeod, K.F.3
-
20
-
-
84921798595
-
Caloric restriction mimetics: Towards a molecular definition
-
1:CAS:528:DC%2BC2cXhsFOlt7zI 25212602
-
Madeo F, Pietrocola F, Eisenberg T, Kroemer G (2014) Caloric restriction mimetics: towards a molecular definition. Nat Rev Drug Discov 13:727-740
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 727-740
-
-
Madeo, F.1
Pietrocola, F.2
Eisenberg, T.3
Kroemer, G.4
-
21
-
-
84862908818
-
AMPK and mTOR in cellular energy homeostasis and drug targets
-
1:CAS:528:DC%2BC38XjsV2nt7c%3D 22017684
-
Inoki K, Kim J, Guan KL (2012) AMPK and mTOR in cellular energy homeostasis and drug targets. Annu Rev Pharmacol Toxicol 52:381-400
-
(2012)
Annu Rev Pharmacol Toxicol
, vol.52
, pp. 381-400
-
-
Inoki, K.1
Kim, J.2
Guan, K.L.3
-
22
-
-
84898605672
-
Can trehalose prevent neurodegeneration? Insights from experimental studies
-
1:CAS:528:DC%2BC2cXmt1Ggtbo%3D 24568549
-
Emanuele E (2014) Can trehalose prevent neurodegeneration? Insights from experimental studies. Curr Drug Targets 15:551-557
-
(2014)
Curr Drug Targets
, vol.15
, pp. 551-557
-
-
Emanuele, E.1
-
23
-
-
84884634690
-
Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: Autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers
-
1:CAS:528:DC%2BC3sXhsV2gtb7L 24059496
-
Sarkar S (2013) Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers. Biochem Soc Trans 41:1103-1130
-
(2013)
Biochem Soc Trans
, vol.41
, pp. 1103-1130
-
-
Sarkar, S.1
-
24
-
-
33745751085
-
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
-
1:CAS:528:DC%2BD28XmsVentb8%3D 16799551
-
Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH, Jung JU (2006) Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol 8:688-699
-
(2006)
Nat Cell Biol
, vol.8
, pp. 688-699
-
-
Liang, C.1
Feng, P.2
Ku, B.3
Dotan, I.4
Canaani, D.5
Oh, B.H.6
Jung, J.U.7
-
25
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
2654259 1:CAS:528:DC%2BD1cXksFGrtLg%3D 18188003
-
Klionsky DJ, Abeliovich H, Agostinis P et al (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4:151-175
-
(2008)
Autophagy
, vol.4
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
-
26
-
-
75749122303
-
Methods in mammalian autophagy research
-
2852113 1:CAS:528:DC%2BC3cXlt1KlsLc%3D 20144757
-
Mizushima N, Yoshimori T, Levine B (2010) Methods in mammalian autophagy research. Cell 140:313-326
-
(2010)
Cell
, vol.140
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
-
27
-
-
84887623828
-
Crosstalk between apoptosis, necrosis and autophagy
-
1:CAS:528:DC%2BC3sXhtVCgsLfK 23770045
-
Nikoletopoulou V, Markaki M, Palikaras K, Tavernarakis N (2013) Crosstalk between apoptosis, necrosis and autophagy. Biochim Biophys Acta 1833:3448-3459
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 3448-3459
-
-
Nikoletopoulou, V.1
Markaki, M.2
Palikaras, K.3
Tavernarakis, N.4
-
28
-
-
84882630172
-
Crosstalk between apoptosis and autophagy: Molecular mechanisms and therapeutic strategies in cancer
-
4147769 25278778
-
El-Khattouti A, Selimovic D, Haikel Y, Hassan M (2013) Crosstalk between apoptosis and autophagy: molecular mechanisms and therapeutic strategies in cancer. J Cell Death 6:37-55
-
(2013)
J Cell Death
, vol.6
, pp. 37-55
-
-
El-Khattouti, A.1
Selimovic, D.2
Haikel, Y.3
Hassan, M.4
-
29
-
-
34250308322
-
Apoptosis: A review of programmed cell death
-
2117903 1:CAS:528:DC%2BD2sXmtlWmtb4%3D 17562483
-
Elmore S (2007) Apoptosis: a review of programmed cell death. Toxicol Pathol 35:495-516
-
(2007)
Toxicol Pathol
, vol.35
, pp. 495-516
-
-
Elmore, S.1
-
30
-
-
84906901988
-
Modulation of apoptosis sensitivity through the interplay with autophagic and proteasomal degradation pathways
-
4040655 1:CAS:528:DC%2BC2cXhsVCntLg%3D 24457955
-
Delgado ME, Dyck L, Laussmann MA, Rehm M (2014) Modulation of apoptosis sensitivity through the interplay with autophagic and proteasomal degradation pathways. Cell Death Dis 5:e1011
-
(2014)
Cell Death Dis
, vol.5
, pp. e1011
-
-
Delgado, M.E.1
Dyck, L.2
Laussmann, M.A.3
Rehm, M.4
-
31
-
-
84891102849
-
The role of cell signalling in the crosstalk between autophagy and apoptosis
-
4054685 1:CAS:528:DC%2BC2cXhtFOksbg%3D 24308968
-
Booth LA, Tavallai S, Hamed HA, Cruickshanks N, Dent P (2014) The role of cell signalling in the crosstalk between autophagy and apoptosis. Cell Signal 26:549-555
-
(2014)
Cell Signal
, vol.26
, pp. 549-555
-
-
Booth, L.A.1
Tavallai, S.2
Hamed, H.A.3
Cruickshanks, N.4
Dent, P.5
-
32
-
-
84871250128
-
Sphingolipids: Regulators of crosstalk between apoptosis and autophagy
-
3520539 1:CAS:528:DC%2BC3sXhtF2htbw%3D 23152582
-
Young MM, Kester M, Wang HG (2013) Sphingolipids: regulators of crosstalk between apoptosis and autophagy. J Lipid Res 54:5-19
-
(2013)
J Lipid Res
, vol.54
, pp. 5-19
-
-
Young, M.M.1
Kester, M.2
Wang, H.G.3
-
33
-
-
84907960228
-
The pleiotropic roles of sphingolipid signaling in autophagy
-
4047895 1:CAS:528:DC%2BC2cXos1alsrc%3D 24853423
-
Li Y, Li S, Qin X, Hou W, Dong H, Yao L, Xiong L (2014) The pleiotropic roles of sphingolipid signaling in autophagy. Cell Death Dis 5:e1245
-
(2014)
Cell Death Dis
, vol.5
, pp. e1245
-
-
Li, Y.1
Li, S.2
Qin, X.3
Hou, W.4
Dong, H.5
Yao, L.6
Xiong, L.7
-
34
-
-
84901936622
-
Sphingolipid metabolites in inflammatory disease
-
4320971 1:CAS:528:DC%2BC2cXhtFygs77L 24899305
-
Maceyka M, Spiegel S (2014) Sphingolipid metabolites in inflammatory disease. Nature 510:58-67
-
(2014)
Nature
, vol.510
, pp. 58-67
-
-
MacEyka, M.1
Spiegel, S.2
-
35
-
-
84897954261
-
The role of sphingomyelin and sphingomyelin synthases in cell death, proliferation and migration-from cell and animal models to human disorders
-
1:CAS:528:DC%2BC2cXksFeksQ%3D%3D 24355909
-
Taniguchi M, Okazaki T (2014) The role of sphingomyelin and sphingomyelin synthases in cell death, proliferation and migration-from cell and animal models to human disorders. Biochim Biophys Acta 1841:692-703
-
(2014)
Biochim Biophys Acta
, vol.1841
, pp. 692-703
-
-
Taniguchi, M.1
Okazaki, T.2
-
36
-
-
85027956768
-
Impact of sphingomyelin synthase 1 deficiency on sphingolipid metabolism and atherosclerosis in mice
-
3444302 1:CAS:528:DC%2BC38XpvV2msbc%3D 22580896
-
Li Z, Fan Y, Liu J et al (2012) Impact of sphingomyelin synthase 1 deficiency on sphingolipid metabolism and atherosclerosis in mice. Arterioscler Thromb Vasc Biol 32:1577-1584
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 1577-1584
-
-
Li, Z.1
Fan, Y.2
Liu, J.3
-
37
-
-
52449124284
-
Sphingomyelin synthase 2 deficiency attenuates NFkappaB activation
-
1:CAS:528:DC%2BD1cXosVeru7c%3D 18566297
-
Hailemariam TK, Huan C, Liu J et al (2008) Sphingomyelin synthase 2 deficiency attenuates NFkappaB activation. Arterioscler Thromb Vasc Biol 28:1519-1526
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1519-1526
-
-
Hailemariam, T.K.1
Huan, C.2
Liu, J.3
-
38
-
-
79952791299
-
Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null mice
-
3030399 1:CAS:528:DC%2BC3MXhtFKku74%3D 21115496
-
Yano M, Watanabe K, Yamamoto T et al (2011) Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null mice. J Biol Chem 286:3992-4002
-
(2011)
J Biol Chem
, vol.286
, pp. 3992-4002
-
-
Yano, M.1
Watanabe, K.2
Yamamoto, T.3
-
39
-
-
70450240715
-
Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas
-
2785198 1:CAS:528:DC%2BD1MXhsVCjtbzF 19801672
-
Imgrund S, Hartmann D, Farwanah H et al (2009) Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas. J Biol Chem 284:33549-33560
-
(2009)
J Biol Chem
, vol.284
, pp. 33549-33560
-
-
Imgrund, S.1
Hartmann, D.2
Farwanah, H.3
-
40
-
-
84880518566
-
Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities
-
3774410 1:CAS:528:DC%2BC3sXhtFeksbzL 23760501
-
Ebel P, Vom Dorp K, Petrasch-Parwez E et al (2013) Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities. J Biol Chem 288:21433-21447
-
(2013)
J Biol Chem
, vol.288
, pp. 21433-21447
-
-
Ebel, P.1
Vom Dorp, K.2
Petrasch-Parwez, E.3
-
41
-
-
33845596453
-
Gangliosides as components of lipid membrane domains
-
1:CAS:528:DC%2BD28XhtlChtbrP 16982663
-
Sonnino S, Mauri L, Chigorno V, Prinetti A (2007) Gangliosides as components of lipid membrane domains. Glycobiology 17:1R-13R
-
(2007)
Glycobiology
, vol.17
, pp. 1R-13R
-
-
Sonnino, S.1
Mauri, L.2
Chigorno, V.3
Prinetti, A.4
-
43
-
-
84887467272
-
Constitutive localization of DR4 in lipid rafts is mandatory for TRAIL-induced apoptosis in B-cell hematologic malignancies
-
3920963 1:CAS:528:DC%2BC3sXhs1OltbbE 24136227
-
Marconi M, Ascione B, Ciarlo L et al (2013) Constitutive localization of DR4 in lipid rafts is mandatory for TRAIL-induced apoptosis in B-cell hematologic malignancies. Cell Death Dis 4:e863
-
(2013)
Cell Death Dis
, vol.4
, pp. e863
-
-
Marconi, M.1
Ascione, B.2
Ciarlo, L.3
-
44
-
-
74849118341
-
Lipid rafts as a membrane-organizing principle
-
1:CAS:528:DC%2BD1MXhs1WksrfJ 20044567
-
Lingwood D, Simons K (2010) Lipid rafts as a membrane-organizing principle. Science 327:46-50
-
(2010)
Science
, vol.327
, pp. 46-50
-
-
Lingwood, D.1
Simons, K.2
-
45
-
-
84885871697
-
Dynamics of mitochondrial raft-like microdomains in cell life and death
-
3376069 1:CAS:528:DC%2BC38XnslOrs7s%3D 22808338
-
Sorice M, Mattei V, Matarrese P et al (2012) Dynamics of mitochondrial raft-like microdomains in cell life and death. Commun Integr Biol 5:217-219
-
(2012)
Commun Integr Biol
, vol.5
, pp. 217-219
-
-
Sorice, M.1
Mattei, V.2
Matarrese, P.3
-
46
-
-
84905647126
-
Molecular recognition of gangliosides and their potential for cancer immunotherapies
-
4104838 25101077
-
Krengel U, Bousquet PA (2014) Molecular recognition of gangliosides and their potential for cancer immunotherapies. Front Immunol 5:325
-
(2014)
Front Immunol
, vol.5
, pp. 325
-
-
Krengel, U.1
Bousquet, P.A.2
-
47
-
-
0029996139
-
Signal transduction through lipid second messengers
-
1:CAS:528:DyaK28XitVWktb8%3D 8791422
-
Spiegel S, Foster D, Kolesnick R (1996) Signal transduction through lipid second messengers. Curr Opin Cell Biol 8:159-167
-
(1996)
Curr Opin Cell Biol
, vol.8
, pp. 159-167
-
-
Spiegel, S.1
Foster, D.2
Kolesnick, R.3
-
48
-
-
0034623715
-
The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis
-
2094390 1:CAS:528:DC%2BD3cXoslymtLk%3D 11027675
-
Siskind LJ, Colombini M (2000) The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis. J Biol Chem 275:38640-38644
-
(2000)
J Biol Chem
, vol.275
, pp. 38640-38644
-
-
Siskind, L.J.1
Colombini, M.2
-
49
-
-
0033529712
-
Commitment to apoptosis by GD3 ganglioside depends on opening of the mitochondrial permeability transition pore
-
1:CAS:528:DyaK1MXlt1Cnsbw%3D 10428836
-
Scorrano L, Petronilli V, Di Lisa F, Bernardi P (1999) Commitment to apoptosis by GD3 ganglioside depends on opening of the mitochondrial permeability transition pore. J Biol Chem 274:22581-22585
-
(1999)
J Biol Chem
, vol.274
, pp. 22581-22585
-
-
Scorrano, L.1
Petronilli, V.2
Di Lisa, F.3
Bernardi, P.4
-
50
-
-
84055176124
-
Recruitment of cellular prion protein to mitochondrial raft-like microdomains contributes to apoptosis execution
-
3237627 1:CAS:528:DC%2BC3MXhs12nsL3M 22031292
-
Mattei V, Matarrese P, Garofalo T et al (2011) Recruitment of cellular prion protein to mitochondrial raft-like microdomains contributes to apoptosis execution. Mol Biol Cell 22:4842-4853
-
(2011)
Mol Biol Cell
, vol.22
, pp. 4842-4853
-
-
Mattei, V.1
Matarrese, P.2
Garofalo, T.3
-
51
-
-
0033214095
-
Cathepsin D targeted by acid sphingomyelinase-derived ceramide
-
1171596 1:CAS:528:DyaK1MXntFKqs7o%3D 10508159
-
Heinrich M, Wickel M, Schneider-Brachert W et al (1999) Cathepsin D targeted by acid sphingomyelinase-derived ceramide. EMBO J 18:5252-5263
-
(1999)
EMBO J
, vol.18
, pp. 5252-5263
-
-
Heinrich, M.1
Wickel, M.2
Schneider-Brachert, W.3
-
52
-
-
0034634596
-
Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex
-
1:CAS:528:DC%2BD3cXotFehsrY%3D 10962008
-
Bourbon NA, Yun J, Kester M (2000) Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex. J Biol Chem 275:35617-35623
-
(2000)
J Biol Chem
, vol.275
, pp. 35617-35623
-
-
Bourbon, N.A.1
Yun, J.2
Kester, M.3
-
53
-
-
34247518635
-
Dynamics of lipid raft components during lymphocyte apoptosis: The paradigmatic role of GD3
-
1:CAS:528:DC%2BD2sXksFamsb4%3D 17453161
-
Malorni W, Giammarioli AM, Garofalo T, Sorice M (2007) Dynamics of lipid raft components during lymphocyte apoptosis: the paradigmatic role of GD3. Apoptosis 12:941-949
-
(2007)
Apoptosis
, vol.12
, pp. 941-949
-
-
Malorni, W.1
Giammarioli, A.M.2
Garofalo, T.3
Sorice, M.4
-
54
-
-
67649920937
-
Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells
-
1:CAS:528:DC%2BD1MXosVaisrc%3D 19394759
-
Signorelli P, Munoz-Olaya JM, Gagliostro V, Casas J, Ghidoni R, Fabriàs G (2009) Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells. Cancer Lett 282:238-243
-
(2009)
Cancer Lett
, vol.282
, pp. 238-243
-
-
Signorelli, P.1
Munoz-Olaya, J.M.2
Gagliostro, V.3
Casas, J.4
Ghidoni, R.5
Fabriàs, G.6
-
55
-
-
82255191935
-
Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide
-
3381336 1:CAS:528:DC%2BC3MXhsFaru73J 21400505
-
Jiang Q, Rao X, Kim CY, Freiser H, Zhang Q, Jiang Z, Li G (2012) Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide. Int J Cancer 130:685-693
-
(2012)
Int J Cancer
, vol.130
, pp. 685-693
-
-
Jiang, Q.1
Rao, X.2
Kim, C.Y.3
Freiser, H.4
Zhang, Q.5
Jiang, Z.6
Li, G.7
-
56
-
-
80055079168
-
Dihydroceramide-based response to hypoxia
-
3207482 1:CAS:528:DC%2BC3MXhtlyktb7N 21914808
-
Devlin CM, Lahm T, Hubbard WC et al (2011) Dihydroceramide-based response to hypoxia. J Biol Chem 286:38069-38078
-
(2011)
J Biol Chem
, vol.286
, pp. 38069-38078
-
-
Devlin, C.M.1
Lahm, T.2
Hubbard, W.C.3
-
57
-
-
84897954412
-
Autophagy paradox and ceramide
-
1:CAS:528:DC%2BC3sXhsFGqs7fN 24055889
-
Jiang W, Ogretmen B (2014) Autophagy paradox and ceramide. Biochim Biophys Acta 1841:783-792
-
(2014)
Biochim Biophys Acta
, vol.1841
, pp. 783-792
-
-
Jiang, W.1
Ogretmen, B.2
-
58
-
-
0032569026
-
Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis
-
1:CAS:528:DyaK1cXkt1GgsbY%3D 9632728
-
Zhou H, Summers SA, Birnbaum MJ, Pittman RN (1998) Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis. J Biol Chem 273:16568-16575
-
(1998)
J Biol Chem
, vol.273
, pp. 16568-16575
-
-
Zhou, H.1
Summers, S.A.2
Birnbaum, M.J.3
Pittman, R.N.4
-
59
-
-
2442485884
-
Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1
-
1:CAS:528:DC%2BD2cXjsVKnur4%3D 14970205
-
Scarlatti F, Bauvy C, Ventruti A, Sala G, Cluzeaud F, Vandewalle A, Ghidoni R, Codogno P (2004) Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1. J Biol Chem 279:18384-18391
-
(2004)
J Biol Chem
, vol.279
, pp. 18384-18391
-
-
Scarlatti, F.1
Bauvy, C.2
Ventruti, A.3
Sala, G.4
Cluzeaud, F.5
Vandewalle, A.6
Ghidoni, R.7
Codogno, P.8
-
60
-
-
66349100518
-
P65/RelA modulates BECN1 transcription and autophagy
-
2682036 1:CAS:528:DC%2BD1MXlvFSqu7s%3D 19289499
-
Copetti T, Bertoli C, Dalla E, Demarchi F, Schneider C (2009) p65/RelA modulates BECN1 transcription and autophagy. Mol Cell Biol 29:2594-2608
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2594-2608
-
-
Copetti, T.1
Bertoli, C.2
Dalla, E.3
Demarchi, F.4
Schneider, C.5
-
61
-
-
59149090850
-
Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy
-
2631952 1:CAS:528:DC%2BD1MXpsV2isg%3D%3D 19029119
-
Pattingre S, Bauvy C, Carpentier S, Levade T, Levine B, Codogno P (2009) Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy. J Biol Chem 284:2719-2728
-
(2009)
J Biol Chem
, vol.284
, pp. 2719-2728
-
-
Pattingre, S.1
Bauvy, C.2
Carpentier, S.3
Levade, T.4
Levine, B.5
Codogno, P.6
-
62
-
-
66449115318
-
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
-
2673842 1:CAS:528:DC%2BD1MXlsFyrtrc%3D 19425170
-
Salazar M, Carracedo A, Salanueva IJ et al (2009) Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest 119:1359-1372
-
(2009)
J Clin Invest
, vol.119
, pp. 1359-1372
-
-
Salazar, M.1
Carracedo, A.2
Salanueva, I.J.3
-
63
-
-
78649650469
-
Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy
-
2992289 1:CAS:528:DC%2BC3cXhsVOku7jM 20876532
-
Sims K, Haynes CA, Kelly S et al (2010) Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy. J Biol Chem 285:38568-38579
-
(2010)
J Biol Chem
, vol.285
, pp. 38568-38579
-
-
Sims, K.1
Haynes, C.A.2
Kelly, S.3
-
64
-
-
79960294696
-
Sphingolipid synthesis is involved in autophagy in Saccharomyces cerevisiae
-
1:CAS:528:DC%2BC3MXptVyqt7s%3D 21703229
-
Yamagata M, Obara K, Kihara A (2011) Sphingolipid synthesis is involved in autophagy in Saccharomyces cerevisiae. Biochem Biophys Res Commun 410:786-791
-
(2011)
Biochem Biophys Res Commun
, vol.410
, pp. 786-791
-
-
Yamagata, M.1
Obara, K.2
Kihara, A.3
-
65
-
-
65249142829
-
Ceramide-induced starvation triggers homeostatic autophagy
-
1:CAS:528:DC%2BD1MXnvVyrs7w%3D 19202357
-
Peralta ER, Edinger AL (2009) Ceramide-induced starvation triggers homeostatic autophagy. Autophagy 5:407-409
-
(2009)
Autophagy
, vol.5
, pp. 407-409
-
-
Peralta, E.R.1
Edinger, A.L.2
-
66
-
-
56249108080
-
Ceramide starves cells to death by downregulating nutrient transporter proteins
-
2582319 1:CAS:528:DC%2BD1cXhsVWns7rP 18981422
-
Guenther GG, Peralta ER, Rosales KR, Wong SY, Siskind LJ, Edinger AL (2008) Ceramide starves cells to death by downregulating nutrient transporter proteins. Proc Natl Acad Sci USA 105:17402-17407
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 17402-17407
-
-
Guenther, G.G.1
Peralta, E.R.2
Rosales, K.R.3
Wong, S.Y.4
Siskind, L.J.5
Edinger, A.L.6
-
67
-
-
60149098492
-
The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells
-
1:CAS:528:DC%2BD1cXhsVKlt73K 19060920
-
Li DD, Wang LL, Deng R et al (2009) The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells. Oncogene 28:886-898
-
(2009)
Oncogene
, vol.28
, pp. 886-898
-
-
Li, D.D.1
Wang, L.L.2
Deng, R.3
-
68
-
-
80053372589
-
C-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells
-
3189397 1:CAS:528:DC%2BC3MXhtlGmt7bM 21943220
-
Sun T, Li D, Wang L, Xia L, Ma J, Guan Z, Feng G, Zhu X (2011) c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells. J Transl Med 9:161
-
(2011)
J Transl Med
, vol.9
, pp. 161
-
-
Sun, T.1
Li, D.2
Wang, L.3
Xia, L.4
Ma, J.5
Guan, Z.6
Feng, G.7
Zhu, X.8
-
69
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
2447655 1:CAS:528:DC%2BD1cXksFagtbk%3D 18281291
-
Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB, Gonzalez FJ, Semenza GL (2008) Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem 283:10892-10903
-
(2008)
J Biol Chem
, vol.283
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
Wesley, J.B.6
Gonzalez, F.J.7
Semenza, G.L.8
-
70
-
-
3042562282
-
Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells
-
1:CAS:528:DC%2BD2cXkvFWlsb0%3D 15205343
-
Daido S, Kanzawa T, Yamamoto A, Takeuchi H, Kondo Y, Kondo S (2004) Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells. Cancer Res 64:4286-4293
-
(2004)
Cancer Res
, vol.64
, pp. 4286-4293
-
-
Daido, S.1
Kanzawa, T.2
Yamamoto, A.3
Takeuchi, H.4
Kondo, Y.5
Kondo, S.6
-
71
-
-
84870302121
-
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
-
3689583 1:CAS:528:DC%2BC38Xht1GhtrzM 22922758
-
Sentelle RD, Senkal CE, Jiang W et al (2012) Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy. Nat Chem Biol 8:831-838
-
(2012)
Nat Chem Biol
, vol.8
, pp. 831-838
-
-
Sentelle, R.D.1
Senkal, C.E.2
Jiang, W.3
-
72
-
-
0032103445
-
Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants
-
1219509 1:CAS:528:DyaK1cXkt1Sqtr4%3D 9601083
-
Lanterman MM, Saba JD (1998) Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants. Biochem J 332:525-531
-
(1998)
Biochem J
, vol.332
, pp. 525-531
-
-
Lanterman, M.M.1
Saba, J.D.2
-
73
-
-
33646831810
-
Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation
-
1:CAS:528:DC%2BD28XivVCgurc%3D 16415355
-
Lavieu G, Scarlatti F, Sala G, Carpentier S, Levade T, Ghidoni R, Botti J, Codogno P (2006) Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation. J Biol Chem 281:8518-8527
-
(2006)
J Biol Chem
, vol.281
, pp. 8518-8527
-
-
Lavieu, G.1
Scarlatti, F.2
Sala, G.3
Carpentier, S.4
Levade, T.5
Ghidoni, R.6
Botti, J.7
Codogno, P.8
-
74
-
-
33644974376
-
Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1
-
1:CAS:528:DC%2BD28XjvFChs7g%3D 16281067
-
Bonhoure E, Pchejetski D, Aouali N, Morjani H, Levade T, Kohama T, Cuvillier O (2006) Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1. Leukemia 20:95-102
-
(2006)
Leukemia
, vol.20
, pp. 95-102
-
-
Bonhoure, E.1
Pchejetski, D.2
Aouali, N.3
Morjani, H.4
Levade, T.5
Kohama, T.6
Cuvillier, O.7
-
75
-
-
84891464403
-
Extrinsic sphingosine 1-phosphate activates S1P5 and induces autophagy through generating endoplasmic reticulum stress in human prostate cancer PC-3 cells
-
1:CAS:528:DC%2BC2cXhtFOgtLs%3D 24333325
-
Huang YL, Chang CL, Tang CH, Lin YC, Ju TK, Huang WP, Lee H (2014) Extrinsic sphingosine 1-phosphate activates S1P5 and induces autophagy through generating endoplasmic reticulum stress in human prostate cancer PC-3 cells. Cell Signal 26:611-618
-
(2014)
Cell Signal
, vol.26
, pp. 611-618
-
-
Huang, Y.L.1
Chang, C.L.2
Tang, C.H.3
Lin, Y.C.4
Ju, T.K.5
Huang, W.P.6
Lee, H.7
-
76
-
-
68849112045
-
S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells
-
1:CAS:528:DC%2BD1MXhtVahsbjE 19474291
-
Chang CL, Ho MC, Lee PH, Hsu CY, Huang WP, Lee H (2009) S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells. Am J Physiol Cell Physiol 297:C451-C458
-
(2009)
Am J Physiol Cell Physiol
, vol.297
, pp. C451-C458
-
-
Chang, C.L.1
Ho, M.C.2
Lee, P.H.3
Hsu, C.Y.4
Huang, W.P.5
Lee, H.6
-
77
-
-
77956392170
-
NF-κB as a common signaling pathway in ganglioside-induced autophagic cell death and activation of astrocytes
-
1:CAS:528:DC%2BC3cXhtFGjtrnJ 20554329
-
Hwang J, Lee HJ, Lee WH, Suk K (2010) NF-κB as a common signaling pathway in ganglioside-induced autophagic cell death and activation of astrocytes. J Neuroimmunol 226:66-72
-
(2010)
J Neuroimmunol
, vol.226
, pp. 66-72
-
-
Hwang, J.1
Lee, H.J.2
Lee, W.H.3
Suk, K.4
-
78
-
-
84899768745
-
Evidence for the involvement of GD3 ganglioside in autophagosome formation and maturation
-
1:CAS:528:DC%2BC2cXitFSgtbfE 24589479
-
Matarrese P, Garofalo T, Manganelli V et al (2014) Evidence for the involvement of GD3 ganglioside in autophagosome formation and maturation. Autophagy 10:750-765
-
(2014)
Autophagy
, vol.10
, pp. 750-765
-
-
Matarrese, P.1
Garofalo, T.2
Manganelli, V.3
-
79
-
-
77952240607
-
Association of fission proteins with mitochondrial raft-like domains
-
1:CAS:528:DC%2BC3cXlslyhurw%3D 20075943
-
Ciarlo L, Manganelli V, Garofalo T, Matarrese P, Tinari A, Misasi R, Malorni W, Sorice M (2010) Association of fission proteins with mitochondrial raft-like domains. Cell Death Differ 17:1047-1058
-
(2010)
Cell Death Differ
, vol.17
, pp. 1047-1058
-
-
Ciarlo, L.1
Manganelli, V.2
Garofalo, T.3
Matarrese, P.4
Tinari, A.5
Misasi, R.6
Malorni, W.7
Sorice, M.8
-
80
-
-
84866173763
-
Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease
-
3435539 1:CAS:528:DC%2BC38XhtlOmtLnN 22773688
-
Ciarlo L, Manganelli V, Matarrese P et al (2012) Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease. J Lipid Res 53:2057-2068
-
(2012)
J Lipid Res
, vol.53
, pp. 2057-2068
-
-
Ciarlo, L.1
Manganelli, V.2
Matarrese, P.3
-
81
-
-
84922182997
-
Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion
-
25551774
-
Brandstaetter H, Kishi-Itakura C, Tumbarello DA, Manstein DJ, Buss F (2014) Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion. Autophagy 10(12):2310-2323
-
(2014)
Autophagy
, vol.10
, Issue.12
, pp. 2310-2323
-
-
Brandstaetter, H.1
Kishi-Itakura, C.2
Tumbarello, D.A.3
Manstein, D.J.4
Buss, F.5
-
82
-
-
36249025723
-
Autophagy: Process and function
-
1:CAS:528:DC%2BD2sXhtlGmsrjP 18006683
-
Mizushima N (2007) Autophagy: process and function. Genes Dev 21:2861-2873
-
(2007)
Genes Dev
, vol.21
, pp. 2861-2873
-
-
Mizushima, N.1
-
83
-
-
84920808580
-
Sphingolipids in pulmonary fibrosis
-
1:CAS:528:DC%2BC2cXhslGrs7%2FJ 25446881
-
Huang LS, Natarajan V (2015) Sphingolipids in pulmonary fibrosis. Adv Biol Regul 57:55-63
-
(2015)
Adv Biol Regul
, vol.57
, pp. 55-63
-
-
Huang, L.S.1
Natarajan, V.2
-
84
-
-
84876152661
-
Ceramide expression and cell homeostasis in chronic obstructive pulmonary disease
-
1:CAS:528:DC%2BC3sXlsV2ksL8%3D 23018286
-
Scarpa MC, Baraldo S, Marian E, Turato G, Calabrese F, Saetta M, Maestrelli P (2013) Ceramide expression and cell homeostasis in chronic obstructive pulmonary disease. Respiration 85:342-349
-
(2013)
Respiration
, vol.85
, pp. 342-349
-
-
Scarpa, M.C.1
Baraldo, S.2
Marian, E.3
Turato, G.4
Calabrese, F.5
Saetta, M.6
Maestrelli, P.7
-
85
-
-
84922368172
-
Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: Prevention by correcting lysosomal proteolytic deficits
-
25270989
-
Yang DS, Stavrides P, Saito M et al (2014) Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits. Brain 137:3300-3318
-
(2014)
Brain
, vol.137
, pp. 3300-3318
-
-
Yang, D.S.1
Stavrides, P.2
Saito, M.3
-
86
-
-
84905111905
-
Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease
-
4113944 1:CAS:528:DC%2BC2cXht1KrtrnE 25049335
-
Lee JK, Jin HK, Park MH et al (2014) Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease. J Exp Med 211:1551-1570
-
(2014)
J Exp Med
, vol.211
, pp. 1551-1570
-
-
Lee, J.K.1
Jin, H.K.2
Park, M.H.3
-
87
-
-
84886788013
-
Nitric oxide and sphingolipids control apoptosis and autophagy with a significant impact on Alzheimer's disease
-
1:STN:280:DC%2BC2cjhslamug%3D%3D 24813312
-
Cervia D, Perrotta C, Moscheni C, De Palma C, Clementi E (2013) Nitric oxide and sphingolipids control apoptosis and autophagy with a significant impact on Alzheimer's disease. J Biol Regul Homeost Agents 27:11-22
-
(2013)
J Biol Regul Homeost Agents
, vol.27
, pp. 11-22
-
-
Cervia, D.1
Perrotta, C.2
Moscheni, C.3
De Palma, C.4
Clementi, E.5
-
88
-
-
84896738808
-
Altered levels of α-synuclein and sphingolipids in Batten disease lymphoblast cells
-
1:CAS:528:DC%2BC2cXivFygurY%3D 24534465
-
Kang S, Heo TH, Kim SJ (2014) Altered levels of α-synuclein and sphingolipids in Batten disease lymphoblast cells. Gene 539:181-185
-
(2014)
Gene
, vol.539
, pp. 181-185
-
-
Kang, S.1
Heo, T.H.2
Kim, S.J.3
-
89
-
-
84899957348
-
High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A
-
24488099
-
Gabandé-Rodríguez E, Boya P, Labrador V, Dotti CG, Ledesma MD (2014) High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A. Cell Death Differ 21:864-875
-
(2014)
Cell Death Differ
, vol.21
, pp. 864-875
-
-
Gabandé-Rodríguez, E.1
Boya, P.2
Labrador, V.3
Dotti, C.G.4
Ledesma, M.D.5
-
90
-
-
79851476846
-
Regulation of the NPC2 protein-mediated cholesterol trafficking by membrane lipids
-
1:CAS:528:DC%2BC3MXjt1amtrg%3D 21214551
-
Gallala HD, Breiden B, Sandhoff K (2011) Regulation of the NPC2 protein-mediated cholesterol trafficking by membrane lipids. J Neurochem 116:702-707
-
(2011)
J Neurochem
, vol.116
, pp. 702-707
-
-
Gallala, H.D.1
Breiden, B.2
Sandhoff, K.3
-
91
-
-
77958185918
-
Saposin C mutations in Gaucher disease patients resulting in lysosomal lipid accumulation, saposin C deficiency, but normal prosaposin processing and sorting
-
1:CAS:528:DC%2BC3cXhtVahsLnE 20484222
-
Vaccaro AM, Motta M, Tatti M et al (2010) Saposin C mutations in Gaucher disease patients resulting in lysosomal lipid accumulation, saposin C deficiency, but normal prosaposin processing and sorting. Hum Mol Genet 19:2987-2997
-
(2010)
Hum Mol Genet
, vol.19
, pp. 2987-2997
-
-
Vaccaro, A.M.1
Motta, M.2
Tatti, M.3
-
92
-
-
77955373796
-
Autophagosome maturation is impaired in Fabry disease
-
20431343
-
Chévrier M, Brakch N, Céline L et al (2010) Autophagosome maturation is impaired in Fabry disease. Autophagy 6:589-599
-
(2010)
Autophagy
, vol.6
, pp. 589-599
-
-
Chévrier, M.1
Brakch, N.2
Céline, L.3
-
93
-
-
78149426794
-
Sphingolipids and cancer: Ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance
-
3071292 1:CAS:528:DC%2BC3cXhtl2rsbjJ 21062159
-
Ponnusamy S, Meyers-Needham M, Senkal CE, Saddoughi SA, Sentelle D, Selvam SP, Salas A, Ogretmen B (2010) Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance. Future Oncol 6:1603-1624
-
(2010)
Future Oncol
, vol.6
, pp. 1603-1624
-
-
Ponnusamy, S.1
Meyers-Needham, M.2
Senkal, C.E.3
Saddoughi, S.A.4
Sentelle, D.5
Selvam, S.P.6
Salas, A.7
Ogretmen, B.8
-
94
-
-
84920916855
-
Lipid rafts as major platforms for signaling regulation in cancer
-
1:CAS:528:DC%2BC2cXhvVGksr3O 25465296
-
Mollinedo F, Gajate C (2015) Lipid rafts as major platforms for signaling regulation in cancer. Adv Biol Regul 57:130-146
-
(2015)
Adv Biol Regul
, vol.57
, pp. 130-146
-
-
Mollinedo, F.1
Gajate, C.2
-
95
-
-
84916203333
-
Re-configuration of sphingolipid metabolism by oncogenic transformation
-
4030989 24970218
-
Don AS, Lim XY, Couttas TA (2014) Re-configuration of sphingolipid metabolism by oncogenic transformation. Biomolecules 4:315-353
-
(2014)
Biomolecules
, vol.4
, pp. 315-353
-
-
Don, A.S.1
Lim, X.Y.2
Couttas, T.A.3
-
96
-
-
84896708406
-
Membrane rafts as a novel target in cancer therapy
-
1:CAS:528:DC%2BC2cXmt1Wrsrw%3D 24480320
-
Hryniewicz-Jankowska A, Augoff K, Biernatowska A, Podkalicka J, Sikorski AF (2014) Membrane rafts as a novel target in cancer therapy. Biochim Biophys Acta 1845:155-165
-
(2014)
Biochim Biophys Acta
, vol.1845
, pp. 155-165
-
-
Hryniewicz-Jankowska, A.1
Augoff, K.2
Biernatowska, A.3
Podkalicka, J.4
Sikorski, A.F.5
-
97
-
-
84897954133
-
Sphingolipids and lifespan regulation
-
1:CAS:528:DC%2BC3sXhtlGqs7vN 23954556
-
Huang X, Withers BR, Dickson RC (2014) Sphingolipids and lifespan regulation. Biochim Biophys Acta 1841:657-664
-
(2014)
Biochim Biophys Acta
, vol.1841
, pp. 657-664
-
-
Huang, X.1
Withers, B.R.2
Dickson, R.C.3
-
98
-
-
84868152429
-
Age-dependent changes in the sphingolipid composition of mouse CD4 + T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunction
-
3482221 1:CAS:528:DC%2BC38Xhs1yrt7jK 23110086
-
Molano A, Huang Z, Marko MG et al (2012) Age-dependent changes in the sphingolipid composition of mouse CD4 + T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunction. PLoS ONE 7:e47650
-
(2012)
PLoS ONE
, vol.7
, pp. e47650
-
-
Molano, A.1
Huang, Z.2
Marko, M.G.3
-
99
-
-
84870464044
-
Increased ceramide content and NFκB signaling may contribute to the attenuation of anabolic signaling after resistance exercise in aged males
-
3774074 1:CAS:528:DC%2BC3sXhsFChsLY%3D 23042913
-
Rivas DA, Morris EP, Haran PH et al (2012) Increased ceramide content and NFκB signaling may contribute to the attenuation of anabolic signaling after resistance exercise in aged males. J Appl Physiol 113:1727-1736
-
(2012)
J Appl Physiol
, vol.113
, pp. 1727-1736
-
-
Rivas, D.A.1
Morris, E.P.2
Haran, P.H.3
-
100
-
-
0028874728
-
Gangliosides and Guillain-Barré syndrome
-
1:STN:280:DyaK28%2FpsFSrsA%3D%3D 7490603
-
Raschetti R, Maggini M, Popoli P et al (1995) Gangliosides and Guillain-Barré syndrome. J Clin Epidemiol 48:1399-1405
-
(1995)
J Clin Epidemiol
, vol.48
, pp. 1399-1405
-
-
Raschetti, R.1
Maggini, M.2
Popoli, P.3
-
101
-
-
70349659022
-
Raft component GD3 associates with tubulin following CD95/Fas ligation
-
1:CAS:528:DC%2BD1MXht1GjtLnJ 19509307
-
Sorice M, Matarrese P, Tinari A et al (2009) Raft component GD3 associates with tubulin following CD95/Fas ligation. FASEB J 23:3298-3308
-
(2009)
FASEB J
, vol.23
, pp. 3298-3308
-
-
Sorice, M.1
Matarrese, P.2
Tinari, A.3
-
102
-
-
78650682926
-
Sphingolipids and expression regulation of genes in cancer
-
3012148 1:CAS:528:DC%2BC3cXhs1Wkt7fF 20970453
-
Patwardhan GA, Liu YY (2011) Sphingolipids and expression regulation of genes in cancer. Prog Lipid Res 50:104-114
-
(2011)
Prog Lipid Res
, vol.50
, pp. 104-114
-
-
Patwardhan, G.A.1
Liu, Y.Y.2
-
103
-
-
41949099869
-
Dissecting lipid raft facilitated cell signaling pathways in cancer
-
1:CAS:528:DC%2BD1cXkvFWlur8%3D 18166162
-
Patra SK (2008) Dissecting lipid raft facilitated cell signaling pathways in cancer. Biochim Biophys Acta 1785:182-206
-
(2008)
Biochim Biophys Acta
, vol.1785
, pp. 182-206
-
-
Patra, S.K.1
-
104
-
-
33847706096
-
Lipid rafts in health and disease
-
1:CAS:528:DC%2BD2sXhslCksb0%3D 17064251
-
Michel V, Bakovic M (2007) Lipid rafts in health and disease. Biol Cell 99:129-140
-
(2007)
Biol Cell
, vol.99
, pp. 129-140
-
-
Michel, V.1
Bakovic, M.2
-
105
-
-
60549091933
-
Tau deletion exacerbates the phenotype of Niemann-Pick type C mice and implicates autophagy in pathogenesis
-
2646181 1:CAS:528:DC%2BD1MXhvV2jt7w%3D 19074461
-
Pacheco CD, Elrick MJ, Lieberman AP (2009) Tau deletion exacerbates the phenotype of Niemann-Pick type C mice and implicates autophagy in pathogenesis. Hum Mol Genet 18:956-965
-
(2009)
Hum Mol Genet
, vol.18
, pp. 956-965
-
-
Pacheco, C.D.1
Elrick, M.J.2
Lieberman, A.P.3
-
106
-
-
67649275699
-
Mechanisms and consequences of impaired lipid trafficking in Niemann-Pick type C1-deficient mammalian cells
-
1:CAS:528:DC%2BD1MXnt1Gnsbo%3D 19416638
-
Karten B, Peake KB, Vance JE (2009) Mechanisms and consequences of impaired lipid trafficking in Niemann-Pick type C1-deficient mammalian cells. Biochim Biophys Acta 1791:659-670
-
(2009)
Biochim Biophys Acta
, vol.1791
, pp. 659-670
-
-
Karten, B.1
Peake, K.B.2
Vance, J.E.3
-
107
-
-
34548860918
-
Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain
-
1959498 1:CAS:528:DC%2BD2sXhtV2murbE 17631520
-
Liao G, Yao Y, Liu J, Yu Z, Cheung S, Xie A, Liang X, Bi X (2007) Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain. Am J Pathol 171:962-975
-
(2007)
Am J Pathol
, vol.171
, pp. 962-975
-
-
Liao, G.1
Yao, Y.2
Liu, J.3
Yu, Z.4
Cheung, S.5
Xie, A.6
Liang, X.7
Bi, X.8
-
108
-
-
67349113991
-
Association of autophagy with cholesterol-accumulated compartments in Niemann-Pick disease type C cells
-
1:CAS:528:DC%2BD1MXmtVejur4%3D 19342246
-
Ishibashi S, Yamazaki T, Okamoto K (2009) Association of autophagy with cholesterol-accumulated compartments in Niemann-Pick disease type C cells. J Clin Neurosci 16:954-959
-
(2009)
J Clin Neurosci
, vol.16
, pp. 954-959
-
-
Ishibashi, S.1
Yamazaki, T.2
Okamoto, K.3
-
110
-
-
79960009804
-
Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies
-
3132082 1:CAS:528:DC%2BC3MXoslCksrk%3D 21700325
-
Mazzulli JR, Xu YH, Sun Y et al (2011) Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies. Cell 146:37-52
-
(2011)
Cell
, vol.146
, pp. 37-52
-
-
Mazzulli, J.R.1
Xu, Y.H.2
Sun, Y.3
-
111
-
-
84868628424
-
Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes
-
3484448 1:CAS:528:DC%2BC38Xhs1Cis7fE 23023704
-
Russo SB, Baicu CF, Van Laer A, Geng T, Kasiganesan H, Zile MR, Cowart LA (2012) Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes. J Clin Invest 122:3919-3930
-
(2012)
J Clin Invest
, vol.122
, pp. 3919-3930
-
-
Russo, S.B.1
Baicu, C.F.2
Van Laer, A.3
Geng, T.4
Kasiganesan, H.5
Zile, M.R.6
Cowart, L.A.7
-
112
-
-
84873305575
-
Palmitate and lipopolysaccharide trigger synergistic ceramide production in primary macrophages
-
3561515 1:CAS:528:DC%2BC3sXhvFeisr0%3D 23250746
-
Schilling JD, Machkovech HM, He L, Sidhu R, Fujiwara H, Weber K, Ory DS, Schaffer JE (2013) Palmitate and lipopolysaccharide trigger synergistic ceramide production in primary macrophages. J Biol Chem 288:2923-2932
-
(2013)
J Biol Chem
, vol.288
, pp. 2923-2932
-
-
Schilling, J.D.1
Machkovech, H.M.2
He, L.3
Sidhu, R.4
Fujiwara, H.5
Weber, K.6
Ory, D.S.7
Schaffer, J.E.8
|