Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease

Journal of Experimental Medicine

Volumn 211, Issue 8, 2014, Pages 1551-1570

  Lee, Jong Kil ^a,b   Jin, Hee Kyung ^a   Park, Min Hee ^a,b   Kim, Bo Ra ^a,b   Lee, Phil Hyu ^c   Nakauchi, Hiromitsu ^d   Carter, Janet E ^e   He, Xingxuan ^f   Schuchman, Edward H ^f   Bae, Jae Sung ^a,b  

^a Kyungpook National University   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

^d UNIVERSITY OF TOKYO   (Japan)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; SPHINGOLIPID; SPHINGOMYELIN PHOSPHODIESTERASE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BIOGENESIS; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; LIPID METABOLISM; LYSOSOME; MALE; MEMORY DISORDER; MOUSE; NEUROPATHOLOGY; NONHUMAN; PATHOGENESIS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL;

ALKALINE PHOSPHATASE; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; AUTOPHAGY; BRAIN; CELL LINE; HUMANS; INFLAMMATION; LYSOSOMES; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; PRESENILIN-1; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 84905111905     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20132451     Document Type: Article

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