-
1
-
-
66649127821
-
Immunologic aspects of chronic obstructive pulmonary disease
-
Cosio MG, Saetta M, Agusti A: Immunologic aspects of chronic obstructive pulmonary disease. N Engl J Med 2009; 360: 2445-2454.
-
(2009)
N Engl J Med
, vol.360
, pp. 2445-2454
-
-
Cosio, M.G.1
Saetta, M.2
Agusti, A.3
-
2
-
-
18844434417
-
Ceramide upregulation causes pulmonary cell apoptosis and emphysema- like disease in mice
-
Petrache I, Natarajan V, Zhen L, Medler TR, Richter AT, Cho C, Hubbard WC, Berdyshev EV, Tuder RM: Ceramide upregulation causes pulmonary cell apoptosis and emphysema- like disease in mice. Nat Med 2005; 11: 491-498.
-
(2005)
Nat Med
, vol.11
, pp. 491-498
-
-
Petrache, I.1
Natarajan, V.2
Zhen, L.3
Medler, T.R.4
Richter, A.T.5
Cho, C.6
Hubbard, W.C.7
Berdyshev, E.V.8
Tuder, R.M.9
-
4
-
-
33846192839
-
Is autophagy the key mechanism by which the sphingolipid rheostat controls the cell fate decision?
-
Lavieu G, Scarlatti F, Sala G, Levade T, Ghidoni R, Botti J, Codogno P: Is autophagy the key mechanism by which the sphingolipid rheostat controls the cell fate decision? Autophagy 2007; 3: 45-47.
-
(2007)
Autophagy
, vol.3
, pp. 45-47
-
-
Lavieu, G.1
Scarlatti, F.2
Sala, G.3
Levade, T.4
Ghidoni, R.5
Botti, J.6
Codogno, P.7
-
5
-
-
56249108080
-
Ceramide starves cells to death by downregulating nutrient transporter proteins
-
Guenther GG, Peralta ER, Rosales KR, Wong SY, Siskind LJ, Edinger AL: Ceramide starves cells to death by downregulating nutrient transporter proteins. Proc Natl Acad Sci USA 2008; 105: 17402-17407.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 17402-17407
-
-
Guenther, G.G.1
Peralta, E.R.2
Rosales, K.R.3
Wong, S.Y.4
Siskind, L.J.5
Edinger, A.L.6
-
6
-
-
66349092892
-
Ceramide-induced autophagy: To junk or to protect cells?
-
Pattingre S, Bauvy C, Levade T, Levine B, Codogno P: Ceramide-induced autophagy: to junk or to protect cells? Autophagy 2009; 5: 558-560.
-
(2009)
Autophagy
, vol.5
, pp. 558-560
-
-
Pattingre, S.1
Bauvy, C.2
Levade, T.3
Levine, B.4
Codogno, P.5
-
7
-
-
60149098492
-
The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agentsinduced autophagy in cancer cells
-
Li DD, Wang LL, Deng R, Tang J, Shen Y, Guo JF, Wang Y, Xia LP, Feng GK, Liu QQ, Huang WL, Zeng YX, Zhu XF: The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agentsinduced autophagy in cancer cells. Oncogene 2009; 28: 886-898.
-
(2009)
Oncogene
, vol.28
, pp. 886-898
-
-
Li, D.D.1
Wang, L.L.2
Deng, R.3
Tang, J.4
Shen, Y.5
Guo, J.F.6
Wang, Y.7
Xia, L.P.8
Feng, G.K.9
Liu, Q.Q.10
Huang, W.L.11
Zeng, Y.X.12
Zhu, X.F.13
-
8
-
-
3042562282
-
Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells
-
Daido S, Kanzawa T, Yamamoto A, Takeuchi H, Kondo Y, Kondo S: Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells. Cancer Res 2004; 64: 4286-4293.
-
(2004)
Cancer Res
, vol.64
, pp. 4286-4293
-
-
Daido, S.1
Kanzawa, T.2
Yamamoto, A.3
Takeuchi, H.4
Kondo, Y.5
Kondo, S.6
-
9
-
-
61649103107
-
Autophagy in chronic obstructive pulmonary disease: Homeostatic or pathogenic mechanism?
-
Ryter SW, Chen ZH, Kim HP, Choi AM: Autophagy in chronic obstructive pulmonary disease: homeostatic or pathogenic mechanism? Autophagy 2009; 5: 235-237.
-
(2009)
Autophagy
, vol.5
, pp. 235-237
-
-
Ryter, S.W.1
Chen, Z.H.2
Kim, H.P.3
Choi, A.M.4
-
10
-
-
43449112985
-
Pathogenesis of emphysema: From the bench to the bedside
-
Sharafkhaneh A, Hanania NA, Kim V: Pathogenesis of emphysema: from the bench to the bedside. Proc Am Thorac Soc 2008; 5: 475-477.
-
(2008)
Proc Am Thorac Soc
, vol.5
, pp. 475-477
-
-
Sharafkhaneh, A.1
Hanania, N.A.2
Kim, V.3
-
11
-
-
24344450848
-
Marked alveolar apoptosis/ proliferation imbalance in end-stage emphysema
-
Calabrese F, Giacometti C, Beghe B, Rea F, Loy M, Zuin R, Marulli G, Baraldo S, Saetta M, Valente M: Marked alveolar apoptosis/ proliferation imbalance in end-stage emphysema. Respir Res 2005; 6: 14.
-
(2005)
Respir Res
, vol.6
, pp. 14
-
-
Calabrese, F.1
Giacometti, C.2
Beghe, B.3
Rea, F.4
Loy, M.5
Zuin, R.6
Marulli, G.7
Baraldo, S.8
Saetta, M.9
Valente, M.10
-
12
-
-
0034101866
-
Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD
-
Segura-Valdez L, Pardo A, Gaxiola M, Uhal BD, Becerril C, Selman M: Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD. Chest 2000; 117: 684-694.
-
(2000)
Chest
, vol.117
, pp. 684-694
-
-
Segura-Valdez, L.1
Pardo, A.2
Gaxiola, M.3
Uhal, B.D.4
Becerril, C.5
Selman, M.6
-
13
-
-
13844266182
-
Correlation of lung surface area to apoptosis and proliferation in human emphysema
-
Imai K, Mercer BA, Schulman LL, Sonett JR, D'Armiento JM: Correlation of lung surface area to apoptosis and proliferation in human emphysema. Eur Respir J 2005; 25: 250-258.
-
(2005)
Eur Respir J
, vol.25
, pp. 250-258
-
-
Imai, K.1
Mercer, B.A.2
Schulman, L.L.3
Sonett, J.R.4
D'Armiento, J.M.5
-
14
-
-
1242306658
-
Increased levels of cell death and proliferation in alveolar wall cells in patients with pulmonary emphysema
-
Yokohori N, Aoshiba K, Nagai A: Increased levels of cell death and proliferation in alveolar wall cells in patients with pulmonary emphysema. Chest 2004; 125: 626-632.
-
(2004)
Chest
, vol.125
, pp. 626-632
-
-
Yokohori, N.1
Aoshiba, K.2
Nagai, A.3
-
15
-
-
0035077330
-
Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema
-
Kasahara Y, Tuder RM, Cool CD, Lynch DA, Flores SC, Voelkel NF: Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am J Respir Crit Care Med 2001; 163: 737-744.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 737-744
-
-
Kasahara, Y.1
Tuder, R.M.2
Cool, C.D.3
Lynch, D.A.4
Flores, S.C.5
Voelkel, N.F.6
-
17
-
-
0032798485
-
CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease
-
Saetta M, Baraldo S, Corbino L, Turato G, Braccioni F, Rea F, Cavallesco G, Tropeano G, Mapp CE, Maestrelli P, Ciaccia A, Fabbri LM: CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999; 160: 711-717.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 711-717
-
-
Saetta, M.1
Baraldo, S.2
Corbino, L.3
Turato, G.4
Braccioni, F.5
Rea, F.6
Cavallesco, G.7
Tropeano, G.8
Mapp, C.E.9
Maestrelli, P.10
Ciaccia, A.11
Fabbri, L.M.12
-
18
-
-
77956641729
-
Ceramide is increased in the lower airway epithelium of people with advanced cystic fibrosis
-
Brodlie M, McKean MC, Johnson GE, Gray J, Fisher AJ, Corris PA, Lordan JL, Ward C: Ceramide is increased in the lower airway epithelium of people with advanced cystic fibrosis. Am J Respir Crit Care Med 2010; 182: 369-375.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 369-375
-
-
Brodlie, M.1
McKean, M.C.2
Johnson, G.E.3
Gray, J.4
Fisher, A.J.5
Corris, P.A.6
Lordan, J.L.7
Ward, C.8
-
19
-
-
0142095498
-
Host defense against Pseudomonas aeruginosa requires ceramiderich membrane rafts
-
Grassmé H, Jendrossek V, Riehle A, von Kürthy G, Berger J, Schwarz H, Weller M, Kolesnick R, Gulbins E: Host defense against Pseudomonas aeruginosa requires ceramiderich membrane rafts. Nat Med 2003; 9: 322-330.
-
(2003)
Nat Med
, vol.9
, pp. 322-330
-
-
Grassmé, H.1
Jendrossek, V.2
Riehle, A.3
Von Kürthy, G.4
Berger, J.5
Schwarz, H.6
Weller, M.7
Kolesnick, R.8
Gulbins, E.9
-
20
-
-
0035175328
-
Mechanisms of Staphylococcus aureus induced apoptosis of human endothelial cells
-
Esen M, Schreiner B, Jendrossek V, Lang F, Fassbender K, Grassmé H, Gulbins E: Mechanisms of Staphylococcus aureus induced apoptosis of human endothelial cells. Apoptosis 2001; 6: 431-439.
-
(2001)
Apoptosis
, vol.6
, pp. 431-439
-
-
Esen, M.1
Schreiner, B.2
Jendrossek, V.3
Lang, F.4
Fassbender, K.5
Grassmé, H.6
Gulbins, E.7
-
21
-
-
34250772801
-
Infections with human rhinovirus induce the formation of distinct functional membrane domains
-
Dreschers S, Franz P, Dumitru C, Wilker B, Jahnke K, Gulbins E: Infections with human rhinovirus induce the formation of distinct functional membrane domains. Cell Physiol Biochem 2007; 20: 241-254.
-
(2007)
Cell Physiol Biochem
, vol.20
, pp. 241-254
-
-
Dreschers, S.1
Franz, P.2
Dumitru, C.3
Wilker, B.4
Jahnke, K.5
Gulbins, E.6
-
22
-
-
78650057959
-
Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages
-
Petrusca DN, Gu Y, Adamowicz JJ, Rush NI, Hubbard WC, Smith PA, Berdyshev EV, Birukov KG, Lee CH, Tuder RM, Twigg HL 3rd, Vandivier RW, Petrache I: Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages. J Biol Chem 2010; 285: 40322-40332.
-
(2010)
J Biol Chem
, vol.285
, pp. 40322-40332
-
-
Petrusca, D.N.1
Gu, Y.2
Adamowicz, J.J.3
Rush, N.I.4
Hubbard, W.C.5
Smith, P.A.6
Berdyshev, E.V.7
Birukov, K.G.8
Lee, C.H.9
Tuder, R.M.10
Twigg III, H.L.11
Vandivier, R.W.12
Petrache, I.13
-
23
-
-
33745905620
-
Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema
-
Demedts IK, Demoor T, Bracke KR, Joos GF, Brusselle GG: Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema. Respir Res 2006; 7: 53.
-
(2006)
Respir Res
, vol.7
, pp. 53
-
-
Demedts, I.K.1
Demoor, T.2
Bracke, K.R.3
Joos, G.F.4
Brusselle, G.G.5
-
25
-
-
0034949094
-
Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema
-
Majo J, Ghezzo H, Cosio MG: Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema. Eur Respir J 2001; 17: 946-953.
-
(2001)
Eur Respir J
, vol.17
, pp. 946-953
-
-
Majo, J.1
Ghezzo, H.2
Cosio, M.G.3
-
26
-
-
14744295733
-
Increased airway epithelial and T-cell apoptosis in COPD remains despite smoking cessation
-
Hodge S, Hodge G, Holmes M, Reynolds PN: Increased airway epithelial and T-cell apoptosis in COPD remains despite smoking cessation. Eur Respir J 2005; 25: 447-454.
-
(2005)
Eur Respir J
, vol.25
, pp. 447-454
-
-
Hodge, S.1
Hodge, G.2
Holmes, M.3
Reynolds, P.N.4
-
28
-
-
53549090696
-
Autophagic proteins regulate cigarette smoke-induced apoptosis: Protective role of heme oxygenase- 1
-
Kim HP, Wang X, Chen ZH, Lee SJ, Huang MH, Wang Y, Ryter SW, Choi AM: Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase- 1. Autophagy 2008; 4: 887-895.
-
(2008)
Autophagy
, vol.4
, pp. 887-895
-
-
Kim, H.P.1
Wang, X.2
Chen, Z.H.3
Lee, S.J.4
Huang, M.H.5
Wang, Y.6
Ryter, S.W.7
Choi, A.M.8
-
29
-
-
53749087325
-
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
-
Chen ZH, Kim HP, Sciurba FC, Lee SJ, Feghali- Bostwick C, Stolz DB, Dhir R, Landreneau RJ, Schuchert MJ, Yousem SA, Nakahira K, Pilewski JM, Lee JS, Zhang Y, Ryter SW, Choi AM: Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One 2008; 3:e3316.
-
(2008)
PLoS One
, vol.3
-
-
Chen, Z.H.1
Kim, H.P.2
Sciurba, F.C.3
Lee, S.J.4
Feghali-Bostwick, C.5
Stolz, D.B.6
Dhir, R.7
Landreneau, R.J.8
Schuchert, M.J.9
Yousem, S.A.10
Nakahira, K.11
Pilewski, J.M.12
Lee, J.S.13
Zhang, Y.14
Ryter, S.W.15
Choi, A.M.16
-
30
-
-
0033607517
-
Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells
-
Xia P, Wang L, Gamble JR, Vadas MA: Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells. J Biol Chem 1999; 274: 34499-34505.
-
(1999)
J Biol Chem
, vol.274
, pp. 34499-34505
-
-
Xia, P.1
Wang, L.2
Gamble, J.R.3
Vadas, M.A.4
-
31
-
-
2942729796
-
Cooperative prosurvival activity by ERK and Akt in human alveolar macrophages is dependent on high levels of acid ceramidase activity
-
Monick MM, Mallampalli RK, Bradford M, McCoy D, Gross TJ, Flaherty DM, Powers LS, Cameron K, Kelly S, Merrill AH Jr, Hunninghake GW: Cooperative prosurvival activity by ERK and Akt in human alveolar macrophages is dependent on high levels of acid ceramidase activity. J Immunol 2004; 173: 123-135.
-
(2004)
J Immunol
, vol.173
, pp. 123-135
-
-
Monick, M.M.1
Mallampalli, R.K.2
Bradford, M.3
McCoy, D.4
Gross, T.J.5
Flaherty, D.M.6
Powers, L.S.7
Cameron, K.8
Kelly, S.9
Merrill Jr., A.H.10
Hunninghake, G.W.11
-
32
-
-
33846691177
-
Nitric oxide enhanced caspase-3 and acidic sphingomyelinase interaction: A novel mechanism by which airway epithelial cells escape ceramide-induced apoptosis
-
Castillo SS, Levy M, Wang C, Thaikoottathil JV, Khan E, Goldkorn T: Nitric oxide enhanced caspase-3 and acidic sphingomyelinase interaction: a novel mechanism by which airway epithelial cells escape ceramide-induced apoptosis. Exp Cell Res 2007; 313: 816-823.
-
(2007)
Exp Cell Res
, vol.313
, pp. 816-823
-
-
Castillo, S.S.1
Levy, M.2
Wang, C.3
Thaikoottathil, J.V.4
Khan, E.5
Goldkorn, T.6
-
33
-
-
33744914050
-
Evolving concepts of apoptosis in idiopathic pulmonary fibrosis
-
Thannickal VJ, Horowitz JC: Evolving concepts of apoptosis in idiopathic pulmonary fibrosis. Proc Am Thorac Soc 2006; 3: 350-356.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 350-356
-
-
Thannickal, V.J.1
Horowitz, J.C.2
|