Association of fission proteins with mitochondrial raft-like domains

Cell Death and Differentiation

Volumn 17, Issue 6, 2010, Pages 1047-1058

  Ciarlo, L ^a   Manganelli, V ^b   Garofalo, T ^b   Matarrese, P ^a   Tinari, A ^a   Misasi, R ^b   Malorni, W ^a   Sorice, M ^b  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Apoptosis; Fission; Lipid rafts; Mitochondria

Indexed keywords

DEATH RECEPTOR; DYNAMIN; DYNAMIN LIKE PROTEIN 1; FAS ANTIGEN; GLYCOSPHINGOLIPID; GUANOSINE TRIPHOSPHATASE; HYBRID PROTEIN; MITOCHONDRIAL PROTEIN; PROTEIN DLP1; PROTEIN HFIS1; SPHINGOSINE ACYLTRANSFERASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL DISRUPTION; CELL ORGANELLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIPID RAFT; MEMBRANE FUSION; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS;

ANTIGENS, CD95; APOPTOSIS; CELLS, CULTURED; CENTRIFUGATION, DENSITY GRADIENT; ENZYME INHIBITORS; FUMONISINS; GANGLIOSIDES; GTP PHOSPHOHYDROLASES; HUMANS; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL PROTEINS; OCTOXYNOL; OXIDOREDUCTASES; RNA INTERFERENCE;

EID: 77952240607     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2009.208     Document Type: Article

References (44)

1. Karbowski M, Youle RJ. Dynamics of mitochondrial morphology in healthy cells and during apoptosis. Cell Death Diff 2003; 10: 870-880.
2. Cerveny KL, Tamura Y, Zhang Z, Jensen RE, Sesaki H. Regulation of mitochondrial fusion and division. Trends Cell Biol 2007; 17: 563-569.
3. Nicholls DG. Mitochondrial function and dysfunction in the cell: its relevance to aging and aging-related disease. Int J Biochem Cell Biol 2002; 34: 1372-1381.
4. Green DR, Kroemer G. The pathophysiology of mitochondrial cell death. Science 2004; 305: 626-629.
5. Olichon A, Emorine LJ, Descoins E, Pelloquin L, Brichese L, Gas N et al. The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space. FEBS Lett 2002; 523: 171-176.
6. Chen H, Detmer SA, Ewald AJ, Grifn EE, Fraser SE, Chan DC. Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol 2003; 160: 189-200.
7. Cipolat S, Martins de Brito O, Dal Zilio B, Scorrano L. OPA1 requires mitofusin 1 to promote mitochondrial fusion. Proc Natl Acad Sci USA 2004; 101: 15927-15932.
8. Yoon Y, Pitts KR, Dahan S, McNiven MA. A novel dynamin-like protein associates with cytoplasmic vesicles and tubules of the endoplasmic reticulum in mammalian cells. J Cell Biol 1998; 140: 779-793.
9. Pitts KR, Yoon Y, Krueger EW, McNiven MA. The dynamin-like protein DLP1 is essential for normal distribution and morphology of the endoplasmic reticulum and mitochondria in mammalian cells. Mol Biol Cell 1999; 10: 4403-4417.
10. Yoon Y, Krueger EW, Oswald BJ, McNiven MA. The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1. Mol Cell Biol 2003; 23: 5409-5420.
11. Zamzami N, Marchetti P, Castedo M, Zanin C, Vayssiere JL, Petit PX et al. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J Exp Med 1995; 181: 1661-1672.
12. Parone PA, Da Cruz S, Tondera D, Mattenberger Y, James DI, Maechler P et al. Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA. PLoS ONE 2008; 3: e3257.
13. Frank S, Gaume B, Bergmann-Leitner ES, Leitner WW, Robert EG, Catez F et al. The role of dynamin-related protein-1, a mediator of mitochondrial fission, in apoptosis. Dev Cell 2001; 1: 515-525.
14. Bossy-Wetzel E, Barsoum MJ, Godzik A, Schwarzenbacher R, Lipton SA. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol 2003; 15: 706-716.
15. Ferri KF, Kroemer GK. Organelle-specific initiation of cell death pathways. Nat Cell Biol 2001; 3: 255-263.
16. Green DR, Evan GI. A matter of life and death. Cancer Cell 2002; 1: 19-30.
17. Scorrano L, Ashiya M, Buttle K, Weiler S, Oakes SA, Mannella CA et al. A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis. Dev Cell 2002; 2: 55-67.
18. Garofalo T, Misasi R, Mattei V, Giammarioli AM, Malorni W, Pontieri GM et al. Association of the death-inducing signaling complex with microdomains after triggering through CD95/Fas. Evidence for caspase-8-ganglioside interaction in T cells. J Biol Chem 2003; 278: 8309-8315.
19. Garcia-Ruiz C, Colell A, Morales A, Calva M, Enrich C, Fernandez-Checa JC. Trafcking of ganglioside GD3 to mitochondria by tumor necrosis factor-alpha. J Biol Chem 2002; 277: 36443-36448.
20. Garofalo T, Giammarioli AM, Misasi R, Tinari A, Manganelli V, Gambardella L et al. Lipid microdomains contribute to apoptosis-associated modifications of mitochondria in T cells. Cell Death Differ 2005; 12: 1378-1389.
21. De Maria R, Lenti L, Malisan F, d'Agostino F, Tomassini B, Zeuner A et al. Requirement for GD3 ganglioside in CD95-and ceramide-induced apoptosis. Science 1997; 277: 1652-1655.
22. Brooks C, Wei Q, Feng L, Dong G, Tao Y, Mei L et al. Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins. Proc Natl Acad Sci USA 2007; 104: 11649-11654.
23. Matarrese P, Tinari A, Mormone E, Bianco GA, Toscano MA, Ascione B et al. Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding, and fission. J Biol Chem 2005; 280: 6969-6985.
24. Cuzzocrea S, Di Paola R, Genovese T, Mazzon E, Esposito E, Crisafulli C et al. Anti-inflammatory and anti-apoptotic effects of fumonisin B1, an inhibitor of ceramide synthase, in a rodent model of splanchnic ischemia and reperfusion injury. J Pharmacol Exp Ther 2008; 327: 45-57.
25. Malorni W, Giammarioli AM, Garofalo T, Sorice M. Dynamics of lipid raft components during lymphocyte apoptosis: the paradigmatic role of GD3. Apoptosis 2007; 12: 941-949.
26. Garofalo T, Tinari A, Matarrese P, Giammarioli AM, Manganelli V, Ciarlo L et al. Do mitochondria act as 'cargo boats' in the journey of GD3 to the nucleus during apoptosis? FEBS Lett 2007; 581: 3899-3903.
27. Scorrano L. Caspase-8 goes cardiolipin: a new platform to provide mitochondria with microdomains of apoptotic signals? J Cell Biol 2008; 183: 579-581.
28. Sorice M, Matarrese P, Tinari A, Giammarioli AM, Garofalo T, Manganelli V et al. Raft component GD3 associates with tubulin following CD95/Fas ligation. FASEB J 2009; 23: 3298-3308.
29. Parone PA, Martinou JC. Mitochondrial fission and apoptosis: an ongoing trial. Biochim Biophys Acta 2006; 1763: 522-530.
30. Martinou JC, Youle RJ. Which came first, the cytochrome c release or the mitochondrial fission? Cell Death Differ 2006; 13: 1291-1295.
31. Suen DF, Norris KL, Youle RJ. Mitochondrial dynamics and apoptosis. Genes Dev 2009; 22: 1577-1590.
32. Cipolat S, Rudka T, Hartmann D, Costa V, Serneels L, Craessaerts K et al. Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling. Cell 2006; 126: 163-175.
33. Frezza C, Cipolat S, Martins de Brito O, Micaroni M, Beznoussenko GV, Rudka T et al. OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion. Cell 2006; 126: 177-189.
34. de Brito OM, Scorrano L. Mitofusin 2: a mitochondria-shaping protein with signaling roles beyond fusion. Antioxid Redox Signal 2008; 10: 621-633.
35. Cereghetti GM, Scorrano L. The many shapes of mitochondrial death. Oncogene 2006; 25: 4717-4724.
36. Satoh M, Hamamoto T, Seo N, Kagawa Y, Endo H. Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria. Biochem Biophys Res Commun 2003; 300: 482-493.
37. Marasas WF, Riley RT, Hendricks KA, Stevens VL, Sadler TW, Gelineau-van Waes J et al. Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize. J Nutr 2004; 134: 711-716.
38. Inokuchi J, Radin NS. Preparation of the active isomer of 1-phenyl-2-decanoylamino-3-morpholino-1-propanol, inhibitor of murine glucocerebroside synthetase. J Lipid Res 1987; 28: 565-571.
39. Malorni W, Garofalo T, Tinari A, Manganelli V, Misasi R, Sorice M. Analyzing lipid raft dynamics during cell apoptosis. Methods Enzymol 2008; 442: 125-140.
40. Rodgers W, Rose JK. Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains. J Cell Biol 1996; 135: 1515-1523.
41. Skibbens JE, Roth MG, Matlin KS. Differential extractability of inuenza virus hemagglutinin during intracellular transport in polarized epithelial cells and nonpolar broblasts. J Cell Biol 1989; 108: 821-832.
42. Svennerholm L, Fredman PA. A procedure for the quantitative isolation of brain gangliosides. Biochim Biophys Acta 1980; 617: 97-109.
43. Williams MA, McCluer RH. The use of Sep-Pak C18 cartridges during the isolation of gangliosides. J Neurochem 1980; 35: 266-269.
44. Zamzami N, Maisse C, Metivier D, Kroemer G. Measurement of membrane permeability and permeability transition of mitochondria. Methods Cell Biol 2001; 65: 147-158.