Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion

Autophagy

Volumn 10, Issue 12, 2014, Pages 2310-2323

  Brandstaetter, Hemma ^a   Kishi Itakura, Chieko ^a   Tumbarello, David A ^a,c   Manstein, Dietmar J ^b   Buss, Folma ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Autophagy; Cholesterol; Electron microscopy; Lipid raft; Lysosome; MYO1C

Indexed keywords

CHOLESTEROL; EPIDERMAL GROWTH FACTOR RECEPTOR; HYDROLASE; MOLECULAR MOTOR; MYOSIN 1C; UNCLASSIFIED DRUG; MYO1C PROTEIN, HUMAN; MYOSIN; MYOSIN I;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL COMPARTMENTALIZATION; CELL FUSION; CELL MEMBRANE; CELL ORGANELLE; CELL SIZE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LIPID COMPOSITION; LIPID RAFT; LYSOSOME; PH; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; CELL LINE; CELL MOTION; ENDOCYTOSIS; ENDOSOME; MEMBRANE FUSION; METABOLISM; PHAGOSOME; PHYSIOLOGY; PROTEIN TRANSPORT;

AUTOPHAGY; CELL LINE; CELL MOVEMENT; ENDOCYTOSIS; ENDOSOMES; HUMANS; LYSOSOMES; MEMBRANE FUSION; MEMBRANE MICRODOMAINS; MYOSIN TYPE I; MYOSINS; PHAGOSOMES; PROTEIN TRANSPORT;

EID: 84922182997     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/15548627.2014.984272     Document Type: Article

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