Palmitate and lipopolysaccharide trigger synergistic ceramide production in primary macrophages

Journal of Biological Chemistry

Volumn 288, Issue 5, 2013, Pages 2923-2932

  Schilling, Joel D ^a   Machkovech, Heather M ^a   He, Li ^a   Sidhu, Rohini ^a   Fujiwara, Hideji ^a   Weber, Kassandra ^a   Ory, Daniel S ^a   Schaffer, Jean E ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; CELLULAR RESPONSE; CERAMIDES; DYSLIPIDEMIAS; HOST DEFENSE; INFLAMMATORY RESPONSE; INFLAMMATORY SIGNALING; INSULIN RESISTANCE; INSULIN SIGNALING; LIPOPOLYSACCHARIDES; METABOLIC DISEASE; SPHINGOLIPIDS; TISSUE REPAIR;

CELL DEATH; ELECTRIC RESISTANCE; INSULIN; MACROPHAGES; SATURATED FATTY ACIDS; TISSUE;

AMIDES;

CERAMIDE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; PALMITIC ACID; SATURATED FATTY ACID; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOPLASMIC RETICULUM; INFLAMMATION; LIPOGENESIS; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; BIOSYNTHETIC PATHWAYS; CELL EXTRACTS; CELLS, CULTURED; CERAMIDES; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PALMITATES; SPHINGOLIPIDS; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84873305575     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.419978     Document Type: Article

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