Constitutive localization of DR4 in lipid rafts is mandatory for TRAIL-induced apoptosis in B-cell hematologic malignancies

Cell Death and Disease

Volumn 4, Issue 10, 2013, Pages

  Marconi, M ^a   Ascione, B ^a   Ciarlo, L ^a   Vona, R ^a   Garofalo, T ^b   Sorice, M ^b   Gianni, A M ^c   Locatelli, S L ^d,e   Carlo Stella, C ^d,e   Malorni, W ^a,f   Matarrese, P ^a,g  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

^d HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^e UNIVERSITY OF MILAN   (Italy)

^f San Raffaele Institute Sulmona   (Italy)

^g Center of Integrated Metabolomics   (Italy)

Author keywords

Apoptosis; Cancer; Death receptors; Hematology; Lipid rafts; TRAIL

Indexed keywords

CD34 ANTIGEN; DEATH RECEPTOR 4; DEATH RECEPTOR 5; GANGLIOSIDE GM3; METHYL BETA CYCLODEXTRIN; PERIFOSINE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL TRANSFORMATION; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; DRUG SENSITIVITY; ENDOTHELIUM CELL; EX VIVO STUDY; FIBROBLAST; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; LIPID RAFT; LYMPHOCYTE; LYMPHOID CELL; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANTIBODIES; ANTIGENS, CD34; APOPTOSIS; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELL SEPARATION; FLOW CYTOMETRY; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MEMBRANE MICRODOMAINS; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; SOLUBILITY; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84887467272     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.389     Document Type: Article

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