-
1
-
-
77950627242
-
IL-1 pathways in inflammation and human diseases
-
Gabay, C., Lamacchia, C., and Palmer, G. (2010) IL-1 pathways in inflammation and human diseases. Nat. Rev. Rheumatol. 6, 232-241
-
(2010)
Nat. Rev. Rheumatol.
, vol.6
, pp. 232-241
-
-
Gabay, C.1
Lamacchia, C.2
Palmer, G.3
-
2
-
-
79953813107
-
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
-
Dinarello, C. A. (2011) Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood 117, 3720-3732
-
(2011)
Blood
, vol.117
, pp. 3720-3732
-
-
Dinarello, C.A.1
-
3
-
-
84878237993
-
Activation and regulation of the inflammasomes
-
Latz, E., Xiao, T. S., and Stutz, A. (2013) Activation and regulation of the inflammasomes. Nat. Rev. Immunol. 13, 397-411
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 397-411
-
-
Latz, E.1
Xiao, T.S.2
Stutz, A.3
-
4
-
-
84858688293
-
Regulation of inflammasome signaling
-
Rathinam, V. A., Vanaja, S. K., and Fitzgerald, K. A. (2012) Regulation of inflammasome signaling. Nat. Immunol. 13, 333-342
-
(2012)
Nat. Immunol.
, vol.13
, pp. 333-342
-
-
Rathinam, V.A.1
Vanaja, S.K.2
Fitzgerald, K.A.3
-
5
-
-
58449083290
-
Pyroptosis: Host cell death and inflammation
-
Bergsbaken, T., Fink, S. L., and Cookson, B. T. (2009) Pyroptosis: host cell death and inflammation. Nat. Rev. Microbiol. 7, 99-109
-
(2009)
Nat. Rev. Microbiol.
, vol.7
, pp. 99-109
-
-
Bergsbaken, T.1
Fink, S.L.2
Cookson, B.T.3
-
6
-
-
84856231635
-
Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways
-
Mocarski, E. S., Upton, J. W., and Kaiser, W. J. (2012) Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways. Nat. Rev. Immunol. 12, 79-88
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 79-88
-
-
Mocarski, E.S.1
Upton, J.W.2
Kaiser, W.J.3
-
7
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser, W. J., Upton, J. W., Long, A. B., Livingston-Rosanoff, D., Daley- Bauer, L. P., Hakem, R., Caspary, T., and Mocarski, E. S. (2011) RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471, 368-372
-
(2011)
Nature
, vol.471
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley- Bauer, L.P.5
Hakem, R.6
Caspary, T.7
Mocarski, E.S.8
-
8
-
-
51049100571
-
Stimulation of Toll-like receptor 3 and 4 induces interleukin-1β maturation by caspase-8
-
Maelfait, J., Vercammen, E., Janssens, S., Schotte, P., Haegman, M., Magez, S., and Beyaert, R. (2008) Stimulation of Toll-like receptor 3 and 4 induces interleukin-1β maturation by caspase-8. J. Exp. Med. 205, 1967-1973
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1967-1973
-
-
Maelfait, J.1
Vercammen, E.2
Janssens, S.3
Schotte, P.4
Haegman, M.5
Magez, S.6
Beyaert, R.7
-
9
-
-
84857404572
-
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation
-
Vince, J. E., Wong, W. W., Gentle, I., Lawlor, K. E., Allam, R., O'Reilly, L., Mason, K., Gross, O., Ma, S., Guarda, G., Anderton, H., Castillo, R., Häcker, G., Silke, J., and Tschopp, J. (2012) Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation. Immunity 36, 215-227
-
(2012)
Immunity
, vol.36
, pp. 215-227
-
-
Vince, J.E.1
Wong, W.W.2
Gentle, I.3
Lawlor, K.E.4
Allam, R.5
O'Reilly, L.6
Mason, K.7
Gross, O.8
Ma, S.9
Guarda, G.10
Anderton, H.11
Castillo, R.12
Häcker, G.13
Silke, J.14
Tschopp, J.15
-
10
-
-
84871125002
-
Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner
-
Bossaller, L., Chiang, P. I., Schmidt-Lauber, C., Ganesan, S., Kaiser, W. J., Rathinam, V. A., Mocarski, E. S., Subramanian, D., Green, D. R., Silverman, N., Fitzgerald, K. A., Marshak-Rothstein, A., and Latz, E. (2012) Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner. J. Immunol. 189, 5508-5512
-
(2012)
J. Immunol.
, vol.189
, pp. 5508-5512
-
-
Bossaller, L.1
Chiang, P.I.2
Schmidt-Lauber, C.3
Ganesan, S.4
Kaiser, W.J.5
Rathinam, V.A.6
Mocarski, E.S.7
Subramanian, D.8
Green, D.R.9
Silverman, N.10
Fitzgerald, K.A.11
Marshak-Rothstein, A.12
Latz, E.13
-
11
-
-
84875970670
-
Fas-mediated inflammatory response in Listeria monocytogenes infection
-
Uchiyama, R., Yonehara, S., and Tsutsui, H. (2013) Fas-mediated inflammatory response in Listeria monocytogenes infection. J. Immunol. 190, 4245-4254
-
(2013)
J. Immunol.
, vol.190
, pp. 4245-4254
-
-
Uchiyama, R.1
Yonehara, S.2
Tsutsui, H.3
-
12
-
-
84896500701
-
Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1 β in response to TLR4 stimulation through a caspase-8-and TRIF-dependent pathway
-
Shenderov, K., Riteau, N., Yip, R., Mayer-Barber, K. D., Oland, S., Hieny, S., Fitzgerald, P., Oberst, A., Dillon, C. P., Green, D. R., Cerundolo, V., and Sher, A. (2014) Cutting edge: endoplasmic reticulum stress licenses macrophages to produce mature IL-1 β in response to TLR4 stimulation through a caspase-8-and TRIF-dependent pathway. J. Immunol. 192, 2029-2033
-
(2014)
J. Immunol.
, vol.192
, pp. 2029-2033
-
-
Shenderov, K.1
Riteau, N.2
Yip, R.3
Mayer-Barber, K.D.4
Oland, S.5
Hieny, S.6
Fitzgerald, P.7
Oberst, A.8
Dillon, C.P.9
Green, D.R.10
Cerundolo, V.11
Sher, A.12
-
13
-
-
84918802996
-
Novel roles for caspase-8 in IL-1β and inflammasome regulation
-
Gurung, P., and Kanneganti, T. D. (2015) Novel roles for caspase-8 in IL-1β and inflammasome regulation. Am. J. Pathol. 185, 17-25
-
(2015)
Am. J. Pathol.
, vol.185
, pp. 17-25
-
-
Gurung, P.1
Kanneganti, T.D.2
-
14
-
-
84927729737
-
Caspase-8 functions as a key mediator of inflammation and pro-IL-1β processing via both canonical and noncanonical pathways
-
Monie, T. P., and Bryant, C. E. (2015) Caspase-8 functions as a key mediator of inflammation and pro-IL-1β processing via both canonical and noncanonical pathways. Immunol. Rev. 265, 181-193
-
(2015)
Immunol. Rev.
, vol.265
, pp. 181-193
-
-
Monie, T.P.1
Bryant, C.E.2
-
15
-
-
84901045151
-
Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death
-
Weng, D., Marty-Roix, R., Ganesan, S., Proulx, M. K., Vladimer, G. I., Kaiser, W. J., Mocarski, E. S., Pouliot, K., Chan, F. K., Kelliher, M. A., Harris, P. A., Bertin, J., Gough, P. J., Shayakhmetov, D. M., Goguen, J. D., et al. (2014) Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death. Proc. Natl. Acad. Sci. U.S.A. 111, 7391-7396
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 7391-7396
-
-
Weng, D.1
Marty-Roix, R.2
Ganesan, S.3
Proulx, M.K.4
Vladimer, G.I.5
Kaiser, W.J.6
Mocarski, E.S.7
Pouliot, K.8
Chan, F.K.9
Kelliher, M.A.10
Harris, P.A.11
Bertin, J.12
Gough, P.J.13
Shayakhmetov, D.M.14
Goguen, J.D.15
-
16
-
-
84901020402
-
Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling
-
Philip, N. H., Dillon, C. P., Snyder, A. G., Fitzgerald, P., Wynosky-Dolfi, M. A., Zwack, E. E., Hu, B., Fitzgerald, L., Mauldin, E. A., Copenhaver, A. M., Shin, S., Wei, L., Parker, M., Zhang, J., Oberst, A., et al. (2014) Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling. Proc. Natl. Acad. Sci. U.S.A. 111, 7385-7390
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 7385-7390
-
-
Philip, N.H.1
Dillon, C.P.2
Snyder, A.G.3
Fitzgerald, P.4
Wynosky-Dolfi, M.A.5
Zwack, E.E.6
Hu, B.7
Fitzgerald, L.8
Mauldin, E.A.9
Copenhaver, A.M.10
Shin, S.11
Wei, L.12
Parker, M.13
Zhang, J.14
Oberst, A.15
-
17
-
-
84887439544
-
Salmonella infection induces recruitment of caspase-8 to the inflammasome to modulate IL-1β production
-
Man, S. M., Tourlomousis, P., Hopkins, L., Monie, T. P., Fitzgerald, K. A., and Bryant, C. E. (2013) Salmonella infection induces recruitment of caspase-8 to the inflammasome to modulate IL-1β production. J. Immunol. 191, 5239-5246
-
(2013)
J. Immunol.
, vol.191
, pp. 5239-5246
-
-
Man, S.M.1
Tourlomousis, P.2
Hopkins, L.3
Monie, T.P.4
Fitzgerald, K.A.5
Bryant, C.E.6
-
18
-
-
84901008921
-
Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex
-
Man, S. M., Hopkins, L. J., Nugent, E., Cox, S., Glück, I. M., Tourlomousis, P., Wright, J. A., Cicuta, P., Monie, T. P., and Bryant, C. E. (2014) Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex. Proc. Natl. Acad. Sci. U.S.A. 111, 7403-7408
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 7403-7408
-
-
Man, S.M.1
Hopkins, L.J.2
Nugent, E.3
Cox, S.4
Glück, I.M.5
Tourlomousis, P.6
Wright, J.A.7
Cicuta, P.8
Monie, T.P.9
Bryant, C.E.10
-
19
-
-
84857175933
-
Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1[β] via a noncanonical caspase-8 inflammasome
-
Gringhuis, S. I., Kaptein, T. M., Wevers, B. A., Theelen, B., van der Vlist, M., Boekhout, T., and Geijtenbeek, T. B. (2012) Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1[β] via a noncanonical caspase-8 inflammasome. Nat. Immunol. 13, 246-254
-
(2012)
Nat. Immunol.
, vol.13
, pp. 246-254
-
-
Gringhuis, S.I.1
Kaptein, T.M.2
Wevers, B.A.3
Theelen, B.4
Van Der Vlist, M.5
Boekhout, T.6
Geijtenbeek, T.B.7
-
20
-
-
84907033643
-
Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans
-
Ganesan, S., Rathinam, V. A., Bossaller, L., Army, K., Kaiser, W. J., Mocarski, E. S., Dillon, C. P., Green, D. R., Mayadas, T. N., Levitz, S. M., Hise, A. G., Silverman, N., and Fitzgerald, K. A. (2014) Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans. J. Immunol. 193, 2519-2530
-
(2014)
J. Immunol.
, vol.193
, pp. 2519-2530
-
-
Ganesan, S.1
Rathinam, V.A.2
Bossaller, L.3
Army, K.4
Kaiser, W.J.5
Mocarski, E.S.6
Dillon, C.P.7
Green, D.R.8
Mayadas, T.N.9
Levitz, S.M.10
Hise, A.G.11
Silverman, N.12
Fitzgerald, K.A.13
-
21
-
-
84885966098
-
Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells
-
Antonopoulos, C., El Sanadi, C., Kaiser, W. J., Mocarski, E. S., and Dubyak, G. R. (2013) Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells. J. Immunol. 191, 4789-4803
-
(2013)
J. Immunol.
, vol.191
, pp. 4789-4803
-
-
Antonopoulos, C.1
El Sanadi, C.2
Kaiser, W.J.3
Mocarski, E.S.4
Dubyak, G.R.5
-
22
-
-
84906852294
-
Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming
-
Allam, R., Lawlor, K. E., Yu, E. C., Mildenhall, A. L., Moujalled, D. M., Lewis, R. S., Ke, F., Mason, K. D., White, M. J., Stacey, K. J., Strasser, A., O'Reilly, L. A., Alexander, W., Kile, B. T., Vaux, D. L., and Vince, J. E. (2014) Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming. EMBO Rep. 15, 982-990
-
(2014)
EMBO Rep.
, vol.15
, pp. 982-990
-
-
Allam, R.1
Lawlor, K.E.2
Yu, E.C.3
Mildenhall, A.L.4
Moujalled, D.M.5
Lewis, R.S.6
Ke, F.7
Mason, K.D.8
White, M.J.9
Stacey, K.J.10
Strasser, A.11
O'Reilly, L.A.12
Alexander, W.13
Kile, B.T.14
Vaux, D.L.15
Vince, J.E.16
-
23
-
-
84894271641
-
FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes
-
Gurung, P., Anand, P. K., Malireddi, R. K., Vande Walle, L., Van Opdenbosch, N., Dillon, C. P., Weinlich, R., Green, D. R., Lamkanfi, M., and Kanneganti, T. D. (2014) FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes. J. Immunol. 192, 1835-1846
-
(2014)
J. Immunol.
, vol.192
, pp. 1835-1846
-
-
Gurung, P.1
Anand, P.K.2
Malireddi, R.K.3
Vande Walle, L.4
Van Opdenbosch, N.5
Dillon, C.P.6
Weinlich, R.7
Green, D.R.8
Lamkanfi, M.9
Kanneganti, T.D.10
-
24
-
-
84882280029
-
AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC
-
Sagulenko, V., Thygesen, S. J., Sester, D. P., Idris, A., Cridland, J. A., Vajjhala, P. R., Roberts, T. L., Schroder, K., Vince, J. E., Hill, J. M., Silke, J., and Stacey, K. J. (2013) AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC. Cell Death Differ. 20, 1149-1160
-
(2013)
Cell Death Differ.
, vol.20
, pp. 1149-1160
-
-
Sagulenko, V.1
Thygesen, S.J.2
Sester, D.P.3
Idris, A.4
Cridland, J.A.5
Vajjhala, P.R.6
Roberts, T.L.7
Schroder, K.8
Vince, J.E.9
Hill, J.M.10
Silke, J.11
Stacey, K.J.12
-
25
-
-
65249164404
-
P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1
-
Qu, Y., Ramachandra, L., Mohr, S., Franchi, L., Harding, C. V., Nunez, G., and Dubyak, G. R. (2009) P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC/NLRP3 inflammasome but is independent of caspase-1. J. Immunol. 182, 5052-5062
-
(2009)
J. Immunol.
, vol.182
, pp. 5052-5062
-
-
Qu, Y.1
Ramachandra, L.2
Mohr, S.3
Franchi, L.4
Harding, C.V.5
Nunez, G.6
Dubyak, G.R.7
-
26
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki, N., Warming, S., Lamkanfi, M., Vande Walle, L., Louie, S., Dong, J., Newton, K., Qu, Y., Liu, J., Heldens, S., Zhang, J., Lee, W. P., Roose- Girma, M., and Dixit, V. M. (2011) Non-canonical inflammasome activation targets caspase-11. Nature 479, 117-121
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
Newton, K.7
Qu, Y.8
Liu, J.9
Heldens, S.10
Zhang, J.11
Lee, W.P.12
Roose- Girma, M.13
Dixit, V.M.14
-
27
-
-
0028984948
-
Mice deficient in IL-1 β-converting enzyme are defective in production of mature IL-1 β and resistant to endotoxic shock
-
Li, P., Allen, H., Banerjee, S., Franklin, S., Herzog, L., Johnston, C., Mc- Dowell, J., Paskind, M., Rodman, L., and Salfeld, J. (1995) Mice deficient in IL-1 β-converting enzyme are defective in production of mature IL-1 β and resistant to endotoxic shock. Cell 80, 401-411
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Franklin, S.4
Herzog, L.5
Johnston, C.6
Mc- Dowell, J.7
Paskind, M.8
Rodman, L.9
Salfeld, J.10
-
28
-
-
0037036114
-
Dynamic imaging of T cell-dendritic cell interactions in lymph nodes
-
Stoll, S., Delon, J., Brotz, T. M., and Germain, R. N. (2002) Dynamic imaging of T cell-dendritic cell interactions in lymph nodes. Science 296, 1873-1876
-
(2002)
Science
, vol.296
, pp. 1873-1876
-
-
Stoll, S.1
Delon, J.2
Brotz, T.M.3
Germain, R.N.4
-
29
-
-
0026751492
-
IL-1 β maturation: Evidence that mature cytokine formation can be induced specifically by nigericin
-
Perregaux, D., Barberia, J., Lanzetti, A. J., Geoghegan, K. F., Carty, T. J., and Gabel, C. A. (1992) IL-1 β maturation: evidence that mature cytokine formation can be induced specifically by nigericin. J. Immunol. 149, 1294-1303
-
(1992)
J. Immunol.
, vol.149
, pp. 1294-1303
-
-
Perregaux, D.1
Barberia, J.2
Lanzetti, A.J.3
Geoghegan, K.F.4
Carty, T.J.5
Gabel, C.A.6
-
30
-
-
0028175838
-
Interleukin-1 β maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity
-
Perregaux, D., and Gabel, C. A. (1994) Interleukin-1 β maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J. Biol. Chem. 269, 15195-15203
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 15195-15203
-
-
Perregaux, D.1
Gabel, C.A.2
-
31
-
-
1942422683
-
Mechanisms of caspase-1 activation by P2X(7) receptor-mediated K+ release
-
Kahlenberg, J. M., and Dubyak, G. R. (2004) Mechanisms of caspase-1 activation by P2X(7) receptor-mediated K+ release. Am. J. Physiol. Cell Physiol. 286, C1100-C1108
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.286
, pp. C1100-C1108
-
-
Kahlenberg, J.M.1
Dubyak, G.R.2
-
32
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
Fernandes-Alnemri, T., Wu, J., Yu, J. W., Datta, P., Miller, B., Jankowski, W., Rosenberg, S., Zhang, J., and Alnemri, E. S. (2007) The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ. 14, 1590-1604
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.W.3
Datta, P.4
Miller, B.5
Jankowski, W.6
Rosenberg, S.7
Zhang, J.8
Alnemri, E.S.9
-
33
-
-
84919385996
-
Dendritic cell IL-1α and IL-1β are polyubiquitinated and degraded by the proteasome
-
Ainscough, J. S., Frank Gerberick, G., Zahedi-Nejad, M., Lopez-Castejon, G., Brough, D., Kimber, I., and Dearman, R. J. (2014) Dendritic cell IL-1α and IL-1β are polyubiquitinated and degraded by the proteasome. J. Biol. Chem. 289, 35582-35592
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 35582-35592
-
-
Ainscough, J.S.1
Frank Gerberick, G.2
Zahedi-Nejad, M.3
Lopez-Castejon, G.4
Brough, D.5
Kimber, I.6
Dearman, R.J.7
-
34
-
-
84927669849
-
K + efflux agonists induce NLRP3 inflammasome activation independently of Ca 2+ signaling
-
Katsnelson, M. A., Rucker, L. G., Russo, H. M., and Dubyak, G. R. (2015) K + efflux agonists induce NLRP3 inflammasome activation independently of Ca 2+ signaling. J. Immunol. 194, 3937-3952
-
(2015)
J. Immunol.
, vol.194
, pp. 3937-3952
-
-
Katsnelson, M.A.1
Rucker, L.G.2
Russo, H.M.3
Dubyak, G.R.4
-
35
-
-
84921305910
-
A20 restricts ubiquitination of prointerleukin-1β protein complexes and suppresses NLRP3 inflammasome activity
-
Duong, B. H., Onizawa, M., Oses-Prieto, J. A., Advincula, R., Burlingame, A., Malynn, B. A., and Ma, A. (2015) A20 restricts ubiquitination of prointerleukin-1β protein complexes and suppresses NLRP3 inflammasome activity. Immunity 42, 55-67
-
(2015)
Immunity
, vol.42
, pp. 55-67
-
-
Duong, B.H.1
Onizawa, M.2
Oses-Prieto, J.A.3
Advincula, R.4
Burlingame, A.5
Malynn, B.A.6
Ma, A.7
-
36
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst, A., Dillon, C. P., Weinlich, R., McCormick, L. L., Fitzgerald, P., Pop, C., Hakem, R., Salvesen, G. S., and Green, D. R. (2011) Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 471, 363-367
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
Hakem, R.7
Salvesen, G.S.8
Green, D.R.9
-
37
-
-
0037376231
-
Blockade of maitotoxin-induced endothelial cell lysis by glycine and L-alanine
-
Estacion, M., Weinberg, J. S., Sinkins, W. G., and Schilling, W. P. (2003) Blockade of maitotoxin-induced endothelial cell lysis by glycine and L-alanine. Am. J. Physiol. Cell Physiol. 284, C1006-C1020
-
(2003)
Am. J. Physiol. Cell Physiol.
, vol.284
, pp. C1006-C1020
-
-
Estacion, M.1
Weinberg, J.S.2
Sinkins, W.G.3
Schilling, W.P.4
-
38
-
-
20044368626
-
Requirement for caspase-8 in NF-κB activation by antigen receptor
-
Su, H., Bidère, N., Zheng, L., Cubre, A., Sakai, K., Dale, J., Salmena, L., Hakem, R., Straus, S., and Lenardo, M. (2005) Requirement for caspase-8 in NF-κB activation by antigen receptor. Science 307, 1465-1468
-
(2005)
Science
, vol.307
, pp. 1465-1468
-
-
Su, H.1
Bidère, N.2
Zheng, L.3
Cubre, A.4
Sakai, K.5
Dale, J.6
Salmena, L.7
Hakem, R.8
Straus, S.9
Lenardo, M.10
-
39
-
-
0034646478
-
Activation of NF-κB by FADD, Casper, and caspase-8
-
Hu, W. H., Johnson, H., and Shu, H. B. (2000) Activation of NF-κB by FADD, Casper, and caspase-8. J. Biol. Chem. 275, 10838-10844
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10838-10844
-
-
Hu, W.H.1
Johnson, H.2
Shu, H.B.3
-
40
-
-
84862909353
-
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
-
Wang, Z., Jiang, H., Chen, S., Du, F., and Wang, X. (2012) The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 148, 228-243
-
(2012)
Cell
, vol.148
, pp. 228-243
-
-
Wang, Z.1
Jiang, H.2
Chen, S.3
Du, F.4
Wang, X.5
-
41
-
-
84908072785
-
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
-
Hildebrand, J. M., Tanzer, M. C., Lucet, I. S., Young, S. N., Spall, S. K., Sharma, P., Pierotti, C., Garnier, J. M., Dobson, R. C., Webb, A. I., Tripaydonis, A., Babon, J. J., Mulcair, M. D., Scanlon, M. J., Alexander, W. S., et al. (2014) Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death. Proc. Natl. Acad. Sci. U.S.A. 111, 15072-15077
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 15072-15077
-
-
Hildebrand, J.M.1
Tanzer, M.C.2
Lucet, I.S.3
Young, S.N.4
Spall, S.K.5
Sharma, P.6
Pierotti, C.7
Garnier, J.M.8
Dobson, R.C.9
Webb, A.I.10
Tripaydonis, A.11
Babon, J.J.12
Mulcair, M.D.13
Scanlon, M.J.14
Alexander, W.S.15
-
42
-
-
84922570928
-
A RIPK3- caspase 8 complex mediates atypical pro-IL-1β processing
-
Moriwaki, K., Bertin, J., Gough, P. J., and Chan, F. K. (2015) A RIPK3- caspase 8 complex mediates atypical pro-IL-1β processing. J. Immunol. 194, 1938-1944
-
(2015)
J. Immunol.
, vol.194
, pp. 1938-1944
-
-
Moriwaki, K.1
Bertin, J.2
Gough, P.J.3
Chan, F.K.4
-
43
-
-
84923674191
-
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
-
Lawlor, K. E., Khan, N., Mildenhall, A., Gerlic, M., Croker, B. A., D'Cruz, A. A., Hall, C., Kaur Spall, S., Anderton, H., Masters, S. L., Rashidi, M., Wicks, I. P., Alexander, W. S., Mitsuuchi, Y., Benetatos, C. A., et al. (2015) RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. Nat. Commun. 6, 6282
-
(2015)
Nat. Commun.
, vol.6
, pp. 6282
-
-
Lawlor, K.E.1
Khan, N.2
Mildenhall, A.3
Gerlic, M.4
Croker, B.A.5
D'Cruz, A.A.6
Hall, C.7
Kaur Spall, S.8
Anderton, H.9
Masters, S.L.10
Rashidi, M.11
Wicks, I.P.12
Alexander, W.S.13
Mitsuuchi, Y.14
Benetatos, C.A.15
-
44
-
-
84896332642
-
Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes
-
Lu, A., Magupalli, V. G., Ruan, J., Yin, Q., Atianand, M. K., Vos, M. R., Schröder, G. F., Fitzgerald, K. A., Wu, H., and Egelman, E. H. (2014) Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes. Cell 156, 1193-1206
-
(2014)
Cell
, vol.156
, pp. 1193-1206
-
-
Lu, A.1
Magupalli, V.G.2
Ruan, J.3
Yin, Q.4
Atianand, M.K.5
Vos, M.R.6
Schröder, G.F.7
Fitzgerald, K.A.8
Wu, H.9
Egelman, E.H.10
-
45
-
-
84896381627
-
Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation
-
Cai, X., Chen, J., Xu, H., Liu, S., Jiang, Q. X., Halfmann, R., and Chen, Z. J. (2014) Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation. Cell 156, 1207-1222
-
(2014)
Cell
, vol.156
, pp. 1207-1222
-
-
Cai, X.1
Chen, J.2
Xu, H.3
Liu, S.4
Jiang, Q.X.5
Halfmann, R.6
Chen, Z.J.7
-
46
-
-
84893850623
-
Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation
-
Wu, Y. H., Kuo, W. C., Wu, Y. J., Yang, K. T., Chen, S. T., Jiang, S. T., Gordy, C., He, Y. W., and Lai, M. Z. (2014) Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation. Cell Death Differ. 21, 451-461
-
(2014)
Cell Death Differ.
, vol.21
, pp. 451-461
-
-
Wu, Y.H.1
Kuo, W.C.2
Wu, Y.J.3
Yang, K.T.4
Chen, S.T.5
Jiang, S.T.6
Gordy, C.7
He, Y.W.8
Lai, M.Z.9
-
47
-
-
84902127968
-
Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation
-
Cuda, C. M., Misharin, A. V., Gierut, A. K., Saber, R., Haines, G. K., 3rd, Hutcheson, J., Hedrick, S. M., Mohan, C., Budinger, G. S., Stehlik, C., and Perlman, H. (2014) Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation. J. Immunol. 192, 5548-5560
-
(2014)
J. Immunol.
, vol.192
, pp. 5548-5560
-
-
Cuda, C.M.1
Misharin, A.V.2
Gierut, A.K.3
Saber, R.4
Haines, G.K.5
Hutcheson, J.6
Hedrick, S.M.7
Mohan, C.8
Budinger, G.S.9
Stehlik, C.10
Perlman, H.11
-
48
-
-
84903480849
-
XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation
-
Yabal, M., Müller, N., Adler, H., Knies, N., Gross, C. J., Damgaard, R. B., Kanegane, H., Ringelhan, M., Kaufmann, T., Heikenwälder, M., Strasser, A., Gross, O., Ruland, J., Peschel, C., Gyrd-Hansen, M., and Jost, P. J. (2014) XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation. Cell Rep. 7, 1796-1808
-
(2014)
Cell Rep.
, vol.7
, pp. 1796-1808
-
-
Yabal, M.1
Müller, N.2
Adler, H.3
Knies, N.4
Gross, C.J.5
Damgaard, R.B.6
Kanegane, H.7
Ringelhan, M.8
Kaufmann, T.9
Heikenwälder, M.10
Strasser, A.11
Gross, O.12
Ruland, J.13
Peschel, C.14
Gyrd-Hansen, M.15
Jost, P.J.16
-
49
-
-
84926164932
-
Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection
-
Karki, R., Man, S. M., Malireddi, R. K., Gurung, P., Vogel, P., Lamkanfi, M., and Kanneganti, T. D. (2015) Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection. Cell Host Microbe 17, 357-368
-
(2015)
Cell Host Microbe
, vol.17
, pp. 357-368
-
-
Karki, R.1
Man, S.M.2
Malireddi, R.K.3
Gurung, P.4
Vogel, P.5
Lamkanfi, M.6
Kanneganti, T.D.7
-
50
-
-
73349114937
-
Multiple interleukin-1β-converting enzymes contribute to inflammatory arthritis
-
Stehlik, C. (2009) Multiple interleukin-1β-converting enzymes contribute to inflammatory arthritis. Arthritis Rheum. 60, 3524-3530
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 3524-3530
-
-
Stehlik, C.1
-
51
-
-
84867903731
-
Cutting edge: IL-1β processing during Pseudomonas aeruginosa infection is mediated by neutrophil serine proteases and is independent of NLRC4 and caspase-1
-
Karmakar, M., Sun, Y., Hise, A. G., Rietsch, A., and Pearlman, E. (2012) Cutting edge: IL-1β processing during Pseudomonas aeruginosa infection is mediated by neutrophil serine proteases and is independent of NLRC4 and caspase-1. J. Immunol. 189, 4231-4235
-
(2012)
J. Immunol.
, vol.189
, pp. 4231-4235
-
-
Karmakar, M.1
Sun, Y.2
Hise, A.G.3
Rietsch, A.4
Pearlman, E.5
-
52
-
-
84911192502
-
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway
-
Wang, X., Jiang, W., Yan, Y., Gong, T., Han, J., Tian, Z., and Zhou, R. (2014) RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway. Nat. Immunol. 15, 1126-1133
-
(2014)
Nat. Immunol.
, vol.15
, pp. 1126-1133
-
-
Wang, X.1
Jiang, W.2
Yan, Y.3
Gong, T.4
Han, J.5
Tian, Z.6
Zhou, R.7
-
53
-
-
84904646033
-
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
-
Baroja-Mazo, A., Martín-Sánchez, F., Gomez, A. I., Martínez, C. M., Amores-Iniesta, J., Compan, V., Barberà-Cremades, M., Yagüe, J., Ruiz- Ortiz, E., Antón, J., Buján, S., Couillin, I., Brough, D., Arostegui, J. I., and Pelegrín, P. (2014) The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response. Nat. Immunol. 15, 738-748
-
(2014)
Nat. Immunol.
, vol.15
, pp. 738-748
-
-
Baroja-Mazo, A.1
Martín-Sánchez, F.2
Gomez, A.I.3
Martínez, C.M.4
Amores-Iniesta, J.5
Compan, V.6
Barberà-Cremades, M.7
Yagüe, J.8
Ruiz- Ortiz, E.9
Antón, J.10
Buján, S.11
Couillin, I.12
Brough, D.13
Arostegui, J.I.14
Pelegrín, P.15
-
54
-
-
84904692363
-
The adaptor ASC has extracellular and "prionoid" activities that propagate inflammation
-
Franklin, B. S., Bossaller, L., De Nardo, D., Ratter, J. M., Stutz, A., Engels, G., Brenker, C., Nordhoff, M., Mirandola, S. R., Al-Amoudi, A., Mangan, M. S., Zimmer, S., Monks, B. G., Fricke, M., Schmidt, R. E., et al. (2014) The adaptor ASC has extracellular and "prionoid" activities that propagate inflammation. Nat. Immunol. 15, 727-737
-
(2014)
Nat. Immunol.
, vol.15
, pp. 727-737
-
-
Franklin, B.S.1
Bossaller, L.2
De Nardo, D.3
Ratter, J.M.4
Stutz, A.5
Engels, G.6
Brenker, C.7
Nordhoff, M.8
Mirandola, S.R.9
Al-Amoudi, A.10
Mangan, M.S.11
Zimmer, S.12
Monks, B.G.13
Fricke, M.14
Schmidt, R.E.15
-
55
-
-
0026485611
-
Molecular cloning of the murine IL-1β converting enzyme cDNA
-
Nett, M. A., Cerretti, D. P., Berson, D. R., Seavitt, J., Gilbert, D. J., Jenkins, N. A., Copeland, N. G., Black, R. A., and Chaplin, D. D. (1992) Molecular cloning of the murine IL-1β converting enzyme cDNA. J. Immunol. 149, 3254-3259
-
(1992)
J. Immunol.
, vol.149
, pp. 3254-3259
-
-
Nett, M.A.1
Cerretti, D.P.2
Berson, D.R.3
Seavitt, J.4
Gilbert, D.J.5
Jenkins, N.A.6
Copeland, N.G.7
Black, R.A.8
Chaplin, D.D.9
-
56
-
-
0026517239
-
Molecular cloning of the interleukin-1β converting enzyme
-
Cerretti, D. P., Kozlosky, C. J., Mosley, B., Nelson, N., Van Ness, K., Greenstreet, T. A., March, C. J., Kronheim, S. R., Druck, T., and Cannizzaro, L. A. (1992) Molecular cloning of the interleukin-1β converting enzyme. Science 256, 97-100
-
(1992)
Science
, vol.256
, pp. 97-100
-
-
Cerretti, D.P.1
Kozlosky, C.J.2
Mosley, B.3
Nelson, N.4
Van Ness, K.5
Greenstreet, T.A.6
March, C.J.7
Kronheim, S.R.8
Druck, T.9
Cannizzaro, L.A.10
-
57
-
-
0034704161
-
Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-γ
-
Lin, X. Y., Choi, M. S., and Porter, A. G. (2000) Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-γ. J. Biol. Chem. 275, 39920-39926
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39920-39926
-
-
Lin, X.Y.1
Choi, M.S.2
Porter, A.G.3
-
58
-
-
79951818190
-
Differential expression of NLRP3 among hematopoietic cells
-
Guarda, G., Zenger, M., Yazdi, A. S., Schroder, K., Ferrero, I., Menu, P., Tardivel, A., Mattmann, C., and Tschopp, J. (2011) Differential expression of NLRP3 among hematopoietic cells. J. Immunol. 186, 2529-2534
-
(2011)
J. Immunol.
, vol.186
, pp. 2529-2534
-
-
Guarda, G.1
Zenger, M.2
Yazdi, A.S.3
Schroder, K.4
Ferrero, I.5
Menu, P.6
Tardivel, A.7
Mattmann, C.8
Tschopp, J.9
-
59
-
-
84881131862
-
Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced atherosclerosis susceptibility
-
Xiao, H., Lu, M., Lin, T. Y., Chen, Z., Chen, G., Wang, W. C., Marin, T., Shentu, T. P., Wen, L., Gongol, B., Sun, W., Liang, X., Chen, J., Huang, H. D., Pedra, J. H., et al. (2013) Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced atherosclerosis susceptibility. Circulation 128, 632-642
-
(2013)
Circulation
, vol.128
, pp. 632-642
-
-
Xiao, H.1
Lu, M.2
Lin, T.Y.3
Chen, Z.4
Chen, G.5
Wang, W.C.6
Marin, T.7
Shentu, T.P.8
Wen, L.9
Gongol, B.10
Sun, W.11
Liang, X.12
Chen, J.13
Huang, H.D.14
Pedra, J.H.15
-
60
-
-
84901252533
-
Endothelial PINK1 mediates the protective effects of NLRP3 deficiency during lethal oxidant injury
-
Zhang, Y., Sauler, M., Shinn, A. S., Gong, H., Haslip, M., Shan, P., Mannam, P., and Lee, P. J. (2014) Endothelial PINK1 mediates the protective effects of NLRP3 deficiency during lethal oxidant injury. J. Immunol. 192, 5296-5304
-
(2014)
J. Immunol.
, vol.192
, pp. 5296-5304
-
-
Zhang, Y.1
Sauler, M.2
Shinn, A.S.3
Gong, H.4
Haslip, M.5
Shan, P.6
Mannam, P.7
Lee, P.J.8
-
61
-
-
84892739389
-
Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
-
Doitsh, G., Galloway, N. L., Geng, X., Yang, Z., Monroe, K. M., Zepeda, O., Hunt, P. W., Hatano, H., Sowinski, S., Muñoz-Arias, I., and Greene, W. C. (2014) Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Nature 505, 509-514
-
(2014)
Nature
, vol.505
, pp. 509-514
-
-
Doitsh, G.1
Galloway, N.L.2
Geng, X.3
Yang, Z.4
Monroe, K.M.5
Zepeda, O.6
Hunt, P.W.7
Hatano, H.8
Sowinski, S.9
Muñoz-Arias, I.10
Greene, W.C.11
-
62
-
-
84866087868
-
AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages
-
Pierini, R., Juruj, C., Perret, M., Jones, C. L., Mangeot, P., Weiss, D. S., and Henry, T. (2012) AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages. Cell Death Differ. 19, 1709-1721
-
(2012)
Cell Death Differ.
, vol.19
, pp. 1709-1721
-
-
Pierini, R.1
Juruj, C.2
Perret, M.3
Jones, C.L.4
Mangeot, P.5
Weiss, D.S.6
Henry, T.7
-
63
-
-
0037470744
-
ASC is an activating adaptor for NF-κB and caspase- 8-dependent apoptosis
-
Masumoto, J., Dowds, T. A., Schaner, P., Chen, F. F., Ogura, Y., Li, M., Zhu, L., Katsuyama, T., Sagara, J., Taniguchi, S., Gumucio, D. L., Núñez, G., and Inohara, N. (2003) ASC is an activating adaptor for NF-κB and caspase- 8-dependent apoptosis. Biochem. Biophys. Res. Commun. 303, 69-73
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.303
, pp. 69-73
-
-
Masumoto, J.1
Dowds, T.A.2
Schaner, P.3
Chen, F.F.4
Ogura, Y.5
Li, M.6
Zhu, L.7
Katsuyama, T.8
Sagara, J.9
Taniguchi, S.10
Gumucio, D.L.11
Núñez, G.12
Inohara, N.13
-
64
-
-
77954842857
-
Activation of ASC induces apoptosis or necrosis, depending on the cell type, and causes tumor eradication
-
Motani, K., Kawase, K., Imamura, R., Kinoshita, T., Kushiyama, H., and Suda, T. (2010) Activation of ASC induces apoptosis or necrosis, depending on the cell type, and causes tumor eradication. Cancer Sci. 101, 1822-1827
-
(2010)
Cancer Sci.
, vol.101
, pp. 1822-1827
-
-
Motani, K.1
Kawase, K.2
Imamura, R.3
Kinoshita, T.4
Kushiyama, H.5
Suda, T.6
-
65
-
-
33947240866
-
Mechanism of ASC-mediated apoptosis: Bid-dependent apoptosis in type II cells
-
Hasegawa, M., Kawase, K., Inohara, N., Imamura, R., Yeh, W. C., Kinoshita, T., and Suda, T. (2007) Mechanism of ASC-mediated apoptosis: bid-dependent apoptosis in type II cells. Oncogene 26, 1748-1756
-
(2007)
Oncogene
, vol.26
, pp. 1748-1756
-
-
Hasegawa, M.1
Kawase, K.2
Inohara, N.3
Imamura, R.4
Yeh, W.C.5
Kinoshita, T.6
Suda, T.7
-
66
-
-
0033607768
-
ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells
-
Masumoto, J., Taniguchi, S., Ayukawa, K., Sarvotham, H., Kishino, T., Niikawa, N., Hidaka, E., Katsuyama, T., Higuchi, T., and Sagara, J. (1999) ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. J. Biol. Chem. 274, 33835-33838
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33835-33838
-
-
Masumoto, J.1
Taniguchi, S.2
Ayukawa, K.3
Sarvotham, H.4
Kishino, T.5
Niikawa, N.6
Hidaka, E.7
Katsuyama, T.8
Higuchi, T.9
Sagara, J.10
-
67
-
-
84900792294
-
Die another way-non-apoptotic mechanisms of cell death
-
Tait, S. W., Ichim, G., and Green, D. R. (2014) Die another way-non-apoptotic mechanisms of cell death. J. Cell Sci. 127, 2135-2144
-
(2014)
J. Cell Sci.
, vol.127
, pp. 2135-2144
-
-
Tait, S.W.1
Ichim, G.2
Green, D.R.3
-
68
-
-
84896541259
-
True grit: Programmed necrosis in antiviral host defense, inflammation, and immunogenicity
-
Mocarski, E. S., Kaiser, W. J., Livingston-Rosanoff, D., Upton, J. W., and Daley-Bauer, L. P. (2014) True grit: programmed necrosis in antiviral host defense, inflammation, and immunogenicity. J. Immunol. 192, 2019-2026
-
(2014)
J. Immunol.
, vol.192
, pp. 2019-2026
-
-
Mocarski, E.S.1
Kaiser, W.J.2
Livingston-Rosanoff, D.3
Upton, J.W.4
Daley-Bauer, L.P.5
-
69
-
-
80052179138
-
Caspase-1-induced pyroptotic cell death
-
Miao, E. A., Rajan, J. V., and Aderem, A. (2011) Caspase-1-induced pyroptotic cell death. Immunol. Rev. 243, 206-214
-
(2011)
Immunol. Rev.
, vol.243
, pp. 206-214
-
-
Miao, E.A.1
Rajan, J.V.2
Aderem, A.3
-
70
-
-
41949127121
-
Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
-
Fink, S. L., Bergsbaken, T., and Cookson, B. T. (2008) Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms. Proc. Natl. Acad. Sci. U.S.A. 105, 4312-4317
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 4312-4317
-
-
Fink, S.L.1
Bergsbaken, T.2
Cookson, B.T.3
-
71
-
-
33749576792
-
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
-
Fink, S. L., and Cookson, B. T. (2006) Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages. Cell. Microbiol. 8, 1812-1825
-
(2006)
Cell. Microbiol.
, vol.8
, pp. 1812-1825
-
-
Fink, S.L.1
Cookson, B.T.2
-
72
-
-
84907916542
-
Chemotherapeutic drugs induce ATP release via caspase-gated pannexin-1 channels and a caspase/pannexin-1-independent mechanism
-
Boyd-Tressler, A., Penuela, S., Laird, D. W., and Dubyak, G. R. (2014) Chemotherapeutic drugs induce ATP release via caspase-gated pannexin-1 channels and a caspase/pannexin-1-independent mechanism. J. Biol. Chem. 289, 27246-27263
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 27246-27263
-
-
Boyd-Tressler, A.1
Penuela, S.2
Laird, D.W.3
Dubyak, G.R.4
-
73
-
-
84859514212
-
Pannexin 1, an ATP release channel, is activated by caspase cleavage of its pore-associated C-terminal autoinhibitory region
-
Sandilos, J. K., Chiu, Y. H., Chekeni, F. B., Armstrong, A. J., Walk, S. F., Ravichandran, K. S., and Bayliss, D. A. (2012) Pannexin 1, an ATP release channel, is activated by caspase cleavage of its pore-associated C-terminal autoinhibitory region. J. Biol. Chem. 287, 11303-11311
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 11303-11311
-
-
Sandilos, J.K.1
Chiu, Y.H.2
Chekeni, F.B.3
Armstrong, A.J.4
Walk, S.F.5
Ravichandran, K.S.6
Bayliss, D.A.7
-
74
-
-
79958034097
-
Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation
-
Qu, Y., Misaghi, S., Newton, K., Gilmour, L. L., Louie, S., Cupp, J. E., Dubyak, G. R., Hackos, D., and Dixit, V. M. (2011) Pannexin-1 is required for ATP release during apoptosis but not for inflammasome activation. J. Immunol. 186, 6553-6561
-
(2011)
J. Immunol.
, vol.186
, pp. 6553-6561
-
-
Qu, Y.1
Misaghi, S.2
Newton, K.3
Gilmour, L.L.4
Louie, S.5
Cupp, J.E.6
Dubyak, G.R.7
Hackos, D.8
Dixit, V.M.9
-
75
-
-
0037851027
-
P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1β release
-
Verhoef, P. A., Estacion, M., Schilling, W., and Dubyak, G. R. (2003) P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1β release. J. Immunol. 170, 5728-5738
-
(2003)
J. Immunol.
, vol.170
, pp. 5728-5738
-
-
Verhoef, P.A.1
Estacion, M.2
Schilling, W.3
Dubyak, G.R.4
-
76
-
-
28244480768
-
Inhibitory effects of chloride on the activation of caspase-1, IL-1β secretion, and cytolysis by the P2X7 receptor
-
Verhoef, P. A., Kertesy, S. B., Lundberg, K., Kahlenberg, J. M., and Dubyak, G. R. (2005) Inhibitory effects of chloride on the activation of caspase-1, IL-1β secretion, and cytolysis by the P2X7 receptor. J. Immunol. 175, 7623-7634
-
(2005)
J. Immunol.
, vol.175
, pp. 7623-7634
-
-
Verhoef, P.A.1
Kertesy, S.B.2
Lundberg, K.3
Kahlenberg, J.M.4
Dubyak, G.R.5
-
77
-
-
4844222940
-
Maitotoxin induces biphasic interleukin-1β secretion and membrane blebbing in murine macrophages
-
Verhoef, P. A., Kertesy, S. B., Estacion, M., Schilling, W. P., and Dubyak, G. R. (2004) Maitotoxin induces biphasic interleukin-1β secretion and membrane blebbing in murine macrophages. Mol. Pharmacol. 66, 909-920
-
(2004)
Mol. Pharmacol.
, vol.66
, pp. 909-920
-
-
Verhoef, P.A.1
Kertesy, S.B.2
Estacion, M.3
Schilling, W.P.4
Dubyak, G.R.5
-
78
-
-
33749337081
-
Palytoxin-induced cell death cascade in bovine aortic endothelial cells
-
Schilling, W. P., Snyder, D., Sinkins, W. G., and Estacion, M. (2006) Palytoxin-induced cell death cascade in bovine aortic endothelial cells. Am. J. Physiol. Cell Physiol. 291, C657-C667
-
(2006)
Am. J. Physiol. Cell Physiol.
, vol.291
, pp. C657-C667
-
-
Schilling, W.P.1
Snyder, D.2
Sinkins, W.G.3
Estacion, M.4
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