-
1
-
-
0033791307
-
Apoptosis signaling
-
Strasser, A., O'Connor, L. & Dixit, V. M. Apoptosis signaling. Annu. Rev. Biochem. 69 , 217-245 (2000).
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 217-245
-
-
Strasser, A.1
O'Connor, L.2
Dixit, V.M.3
-
2
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner, M. O. The biochemistry of apoptosis. Nature 407 , 770-776 (2000).
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
3
-
-
78649901091
-
Alternative cell death mechanisms in development and beyond
-
Yuan, J. & Kroemer, G. Alternative cell death mechanisms in development and beyond. Genes Dev. 24, 2592-2602 (2010).
-
(2010)
Genes Dev.
, vol.24
, pp. 2592-2602
-
-
Yuan, J.1
Kroemer, G.2
-
4
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
Holler, N. et al. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nature Immunol. 1 , 489-495 (2000).
-
(2000)
Nature Immunol.
, vol.1
, pp. 489-495
-
-
Holler, N.1
-
5
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho, Y. S. et al. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137 , 1112-1123 (2009).
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
-
6
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-α
-
He, S. et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-α. Cell 137 , 1100-1111 (2009).
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
-
7
-
-
67650812332
-
RIP3, an energy metabolism reg ulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang, D. W. et al. RIP3, an energy metabolism reg ulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325, 332-336 (2009).
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
-
8
-
-
0037088632
-
Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3
-
DOI 10.1074/jbc.M109488200
-
Sun, X., Yin, J., Starovasnik, M. A., Fairbrother, W. J. & Dixit, V. M. Ident ification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3. J. Biol. Chem. 277 , 9505-9511 (2002). (Pubitemid 34953039)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.11
, pp. 9505-9511
-
-
Sun, X.1
Yin, J.2
Starovasnik, M.A.3
Fairbrother, W.J.4
Dixit, V.M.5
-
9
-
-
75949105922
-
The BCL-2 family reunion
-
Chipuk, J. E., Moldoveanu, T., Llambi, F., Parsons, M. J. & Green, D. R. The BCL-2 family reunion. Mol. Cell 37, 299-310 (2010).
-
(2010)
Mol. Cell
, vol.37
, pp. 299-310
-
-
Chipuk, J.E.1
Moldoveanu, T.2
Llambi, F.3
Parsons, M.J.4
Green, D.R.5
-
10
-
-
0842281645
-
Cell Death: Critical Control Points
-
DOI 10.1016/S0092-8674(04)00046-7
-
Danial, N. N. & Korsmeyer, S. J. Cell death: critical control points. Cell 116, 205-219 (2004). (Pubitemid 38167313)
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
11
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry, N. A. & Lazebnik, Y. Caspases: enemies within. Science 281 , 1312-1316 (1998). (Pubitemid 28406817)
-
(1998)
Science
, vol.281
, Issue.5381
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
12
-
-
69249100500
-
Human caspases: Activation, specificity, and regulation
-
Pop, C. & Salvesen, G. S. Human caspases: activation, specificity, and regulation. J. Biol. Chem. 284, 21777-21781 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 21777-21781
-
-
Pop, C.1
Salvesen, G.S.2
-
13
-
-
79952708318
-
Caspase-8 and Bid: Caught in the act between death receptors and mitochondria
-
Kantari, C. & Walczak, H. Caspase-8 and Bid: caught in the act between death receptors and mitochondria. Biochim. Biophys. Acta 1813, 558-563 (2011).
-
(1813)
Biochim. Biophys. Acta
, pp. 558-563
-
-
Kantari, C.1
Walczak, H.2
-
14
-
-
77957105977
-
Molecular mechanisms of necroptosis: An ordered cellular explosion
-
Vandenabeele, P., Galluzzi, L., Vanden Berghe, T. & Kroemer, G. Molecular mechanisms of necroptosis: an ordered cellular explosion. Nature Rev. Mol. Cell Biol. 11, 700-714 (2010).
-
(2010)
Nature Rev. Mol. Cell Biol.
, vol.11
, pp. 700-714
-
-
Vandenabeele, P.1
Galluzzi, L.2
Vanden Berghe, T.3
Kroemer, G.4
-
15
-
-
4344560197
-
Caspase-8 serves both apoptotic and nonapoptotic roles
-
Kang, T. B. et al. Caspase-8 serves both apoptotic and nonapoptotic roles. J. Immunol. 173, 2976-2984 (2004).
-
(2004)
J. Immunol.
, vol.173
, pp. 2976-2984
-
-
Kang, T.B.1
-
16
-
-
52149095957
-
Mutation of a self-processing site in cas pase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice
-
Kang, T. B. et al. Mutation of a self-processing site in cas pase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice. J. Immunol. 181 , 2522-2532 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 2522-2532
-
-
Kang, T.B.1
-
17
-
-
0036848180
-
Ex vivo whole-embryo culture of caspase-8-dificient embryos normalize their aberrant phenotypes in the developing neural tube and heart
-
DOI 10.1038/sj.cdd.4401090
-
Sakamaki, K. et al. Ex vivo whole-embryo cul ture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart. Cell Death Differ. 9 , 1196-1206 (2002). (Pubitemid 35331766)
-
(2002)
Cell Death and Differentiation
, vol.9
, Issue.11
, pp. 1196-1206
-
-
Sakamaki, K.1
Inoue, T.2
Asano, M.3
Sudo, K.4
Kazama, H.5
Sakagami, J.6
Sakata, S.7
Ozaki, M.8
Nakamura, S.9
Toyokuni, S.10
Osumi, N.11
Iwakura, Y.12
Yonehara, S.13
-
18
-
-
0032143986
-
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
-
Varfolomeev, E. E. et al. Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity 9 , 267-276 (1998). (Pubitemid 28400040)
-
(1998)
Immunity
, vol.9
, Issue.2
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
Chiannilkulchai, N.4
Beckmann, J.S.5
Mett, I.L.6
Rebrikov, D.7
Brodianski, V.M.8
Kemper, O.C.9
Kollet, O.10
Lapidot, T.11
Soffer, D.12
Sobe, T.13
Avraham, K.B.14
Goncharov, T.15
Holtmann, H.16
Lonai, P.17
Wallach, D.18
-
19
-
-
7144263731
-
FADD: Essential for embryo dev elopment and signaling from some, but not all, inducers of apoptosis
-
Yeh, W. C. et al. FADD: essential for embryo dev elopment and signaling from some, but not all, inducers of apoptosis. Science 279, 1954-1958 (1998).
-
(1998)
Science
, vol.279
, pp. 1954-1958
-
-
Yeh, W.C.1
-
20
-
-
0032546387
-
Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1
-
Zhang, J., Cado, D., Chen, A., Kabra, N. H. & Winoto, A. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 392, 296-300 (1998).
-
(1998)
Nature
, vol.392
, pp. 296-300
-
-
Zhang, J.1
Cado, D.2
Chen, A.3
Kabra, N.H.4
Winoto, A.5
-
21
-
-
0033662341
-
Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
-
Yeh, W. C. et al. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity 12 , 633-642 (2000).
-
(2000)
Immunity
, vol.12
, pp. 633-642
-
-
Yeh, W.C.1
-
22
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser, W. J. et al. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471, 368- 372 (2011).
-
(2011)
Nature
, vol.471
, pp. 368-372
-
-
Kaiser, W.J.1
-
23
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIPL complex inhibits RI PK3-dependent necrosis
-
Oberst, A. et al. Catalytic activity of the caspase-8-FLIPL complex inhibits RI PK3-dependent necrosis. Nature 471, 363- 367 (2011).
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
-
24
-
-
79952780505
-
Functional complementation between FADD and RIP1 in embryos and lymphocytes
-
Zhang, H. et al. Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 471, 373-376 (2011).
-
(2011)
Nature
, vol.471
, pp. 373-376
-
-
Zhang, H.1
-
25
-
-
42449123761
-
Expansion and evolution of cell death programmes
-
DOI 10.1038/nrm2393, PII NRM2393
-
Degterev, A. & Yuan, J. Expansion and evolution of cell death programmes. Nature Rev. Mol. Cell Biol. 9, 378-390 (2008). (Pubitemid 351574200)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.5
, pp. 378-390
-
-
Degterev, A.1
Yuan, J.2
-
26
-
-
77955271788
-
The molecular regulation of programmed necrotic cell injury
-
Moquin, D. & Chan, F. K. The molecular regulation of programmed necrotic cell injury. Trends Biochem. Sci. 35, 434-441 (2010).
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 434-441
-
-
Moquin, D.1
Chan, F.K.2
-
27
-
-
77954593965
-
Virus inhibition of RIP3-dependent necrosis
-
Upton, J. W., Kaiser, W. J. & Mocarski, E. S. Virus inhibition of RIP3-dependent necrosis. Cell Host Microbe 7, 302-313 (2010).
-
(2010)
Cell Host Microbe
, vol.7
, pp. 302-313
-
-
Upton, J.W.1
Kaiser, W.J.2
Mocarski, E.S.3
-
28
-
-
0036715377
-
Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA
-
DOI 10.1038/sj.cdd.4401051
-
Kalai, M. et al. Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA. Cell Death Differ. 9 , 981-994 (2002). (Pubitemid 35023613)
-
(2002)
Cell Death and Differentiation
, vol.9
, Issue.9
, pp. 981-994
-
-
Kalai, M.1
Van Loo, G.2
Vanden Berghe, T.3
Meeus, A.4
Burm, W.5
Saelens, X.6
Vandenabeele, P.7
-
29
-
-
79960922705
-
CIAPs block ripoptoso me formation, a RIP1/Caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
-
Feoktistova, M. et al. cIAPs block ripoptoso me formation, a RIP1/Caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol. Cell 43 , 449-463 (2011).
-
(2011)
Mol. Cell
, vol.43
, pp. 449-463
-
-
Feoktistova, M.1
-
30
-
-
79960921946
-
The ripoptosome, a signali ng platform that assembles in response to genotoxic stress and loss of IAPs
-
Tenev, T. et al. The ripoptosome, a signali ng platform that assembles in response to genotoxic stress and loss of IAPs. Mol. Cell 43, 432- 448 (2011).
-
(2011)
Mol. Cell
, vol.43
, pp. 432-448
-
-
Tenev, T.1
-
31
-
-
82455212812
-
'Necrosome'-induced inflammation: Mu st cells die for it?
-
Wallach, D., Kovalenko, A. & Kang, T. B. 'Necrosome'-induced inflammation: mu st cells die for it? Trends Immunol. 32, 505- 509 (2011).
-
(2011)
Trends Immunol.
, vol.32
, pp. 505-509
-
-
Wallach, D.1
Kovalenko, A.2
Kang, T.B.3
-
32
-
-
80755132824
-
The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation
-
Bonnet, M. C. et al. The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation. Immunity 35, 572-582 (2011).
-
(2011)
Immunity
, vol.35
, pp. 572-582
-
-
Bonnet, M.C.1
-
33
-
-
80052850704
-
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
-
Welz, P. S. et al. FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature 477, 330- 334 (2011).
-
(2011)
Nature
, vol.477
, pp. 330-334
-
-
Welz, P.S.1
-
34
-
-
80052845560
-
Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis
-
Gunther, C. et al. Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis. Nature 477, 335-339 (2011).
-
(2011)
Nature
, vol.477
, pp. 335-339
-
-
Gunther, C.1
-
35
-
-
79953240109
-
Linear ubiquitination prevents inflammation and regulates immune signalling
-
Gerlach, B. et al. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature 471, 591- 596 (2011).
-
(2011)
Nature
, vol.471
, pp. 591-596
-
-
Gerlach, B.1
-
36
-
-
62849093368
-
Death receptor signal transducers: Nodes of coordination in immune signaling networks
-
Wilson, N. S., Dixit, V. & Ashkenazi, A. Death receptor signal transducers: nodes of coordination in immune signaling networks. Nature Immunol. 10, 348-355 (2009).
-
(2009)
Nature Immunol.
, vol.10
, pp. 348-355
-
-
Wilson, N.S.1
Dixit, V.2
Ashkenazi, A.3
-
37
-
-
80054852212
-
TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer
-
Walczak, H. TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer. Immunol. Rev. 244, 9-28 (2011).
-
(2011)
Immunol. Rev.
, vol.244
, pp. 9-28
-
-
Walczak, H.1
-
38
-
-
80053602333
-
The regulation of TNF signalling: What a tangled web we weave
-
Silke, J. The regulation of TNF signalling: what a tangled web we weave. Curr. Opin. Immunol. 23 , 620-626 (2011).
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 620-626
-
-
Silke, J.1
-
39
-
-
79952498248
-
TNFR1-induced activation of the classical NF-? B pathway
-
Wajant, H. & Scheurich, P. TNFR1-induced activation of the classical NF-e B pathway. FEBS J. 278, 862- 876 (2011).
-
(2011)
FEBS J.
, vol.278
, pp. 862-876
-
-
Wajant, H.1
Scheurich, P.2
-
40
-
-
0036852215
-
To kill or be killed: Viral evasion of apoptosis
-
DOI 10.1038/ni1102-1013
-
Benedict, C. A., Norris, P. S. & Ware, C. F. To kill or be killed: viral evasion of apoptosis. Nature Immunol. 3, 1013-1018 (2002). (Pubitemid 35363651)
-
(2002)
Nature Immunology
, vol.3
, Issue.11
, pp. 1013-1018
-
-
Benedict, C.A.1
Norris, P.S.2
Ware, C.F.3
-
41
-
-
0028883850
-
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
-
Kischkel, F. C. et al. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 14 , 5579-5588 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 5579-5588
-
-
Kischkel, F.C.1
-
42
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
DOI 10.1016/S0092-8674(00)81266-0
-
Muzio, M. et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85 , 817-827 (1996). (Pubitemid 26193033)
-
(1996)
Cell
, vol.85
, Issue.6
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
Mann, M.11
Krammer, P.H.12
Peter, M.E.13
Dixit, V.M.14
-
43
-
-
0033667778
-
FADD/MORT1 and caspas e-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
-
Sprick, M. R. et al. FADD/MORT1 and caspas e-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 12 , 599-609 (2000).
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
-
44
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi, A. & Dixit, V. M. Death receptors: signaling and modulation. Science 281 , 1305-1308 (1998). (Pubitemid 28406815)
-
(1998)
Science
, vol.281
, Issue.5381
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
45
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
DOI 10.1038/40657
-
Irmler, M. et al. Inhibition of death receptor signals by cellular FLIP. Nature 388, 190-195 (1997). (Pubitemid 27297457)
-
(1997)
Nature
, vol.388
, Issue.6638
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
Bodmer, J.-L.7
Schroter, M.8
Burns, K.9
Mattmann, C.10
Rimoldi, D.11
French, L.E.12
Tschopp, J.13
-
46
-
-
0029858348
-
RIP mediates tumor necrosis factor receptor 1 activation of NF-κB but not Fas/APO-1-initiated apoptosis
-
Ting, A. T., Pimentel-Muinos, F. X. & Seed, B. RIP mediates tumor necrosis factor receptor 1 activation of NF-κB but not Fas/APO-1-initiated apoptosis. EMBO J. 15, 6189-6196 (1996). (Pubitemid 26397891)
-
(1996)
EMBO Journal
, vol.15
, Issue.22
, pp. 6189-6196
-
-
Ting, A.T.1
Pimentel-Muinos, F.X.2
Seed, B.3
-
47
-
-
0029949257
-
TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
-
DOI 10.1016/S1074-7613(00)80252-6
-
Hsu, H., Huang, J., Shu, H. B., Baichwal, V. & Goeddel, D. V. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 4, 387-396 (1996). (Pubitemid 26174054)
-
(1996)
Immunity
, vol.4
, Issue.4
, pp. 387-396
-
-
Hsu, H.1
Huang, J.2
Shu, H.-B.3
Baichwal, V.4
Goeddel, D.V.5
-
48
-
-
0029007855
-
The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
-
Hsu, H., Xiong, J. & Goeddel, D. V. The TNF receptor 1-associated protein TRADD signals cell death and NF-eB activation. Cell 81, 495-504 (1995).
-
(1995)
Cell
, vol.81
, pp. 495-504
-
-
Hsu, H.1
Xiong, J.2
Goeddel, D.V.3
-
49
-
-
0029992609
-
Suppression of TNF-α-induced apoptosis by NF-κB
-
Van Antwerp, D. J., M artin, S. J., Kafri, T., Green, D. R. & Verma, I. M. Suppression of TNF-α-induced apoptosis by NF-κB. Science 274, 787-789 (1996).
-
(1996)
Science
, vol.274
, pp. 787-789
-
-
Van Antwerp, D.J.1
Artin, S.J.M.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
-
50
-
-
44949240664
-
CIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination
-
DOI 10.1016/j.molcel.2008.05.014, PII S1097276508003882
-
Bertrand, M. J. et al. cIAP1 and cIAP2 fa cilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol. Cell 30 , 689-700 (2008). (Pubitemid 351818251)
-
(2008)
Molecular Cell
, vol.30
, Issue.6
, pp. 689-700
-
-
Bertrand, M.J.M.1
Milutinovic, S.2
Dickson, K.M.3
Ho, W.C.4
Boudreault, A.5
Durkin, J.6
Gillard, J.W.7
Jaquith, J.B.8
Morris, S.J.9
Barker, P.A.10
-
51
-
-
72149117664
-
TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (TNF) to efficiently activate NF-κB and to prevent TNF-induced apoptosis
-
Vince, J. E. et al. TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (TNF) to efficiently activate NF-κB and to prevent TNF-induced apoptosis. J. Biol. Chem. 284, 35906-35915 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 35906-35915
-
-
Vince, J.E.1
-
52
-
-
54049155149
-
C-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor α (TNFα)-induced NF-κB activation
-
Varfolomeev, E. et al. c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor α (TNFα)-induced NF-κB activation. J. Biol. Chem. 283, 24295-24299 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 24295-24299
-
-
Varfolomeev, E.1
-
53
-
-
43049152912
-
TNF-α Induces Two Distinct Caspase-8 Activation Pathways
-
DOI 10.1016/j.cell.2008.03.036, PII S0092867408005011
-
Wang, L., Du, F. & Wang, X. TNF-α induces two distinct caspase-8 activation pathways. Cell 133, 693-703 (2008). (Pubitemid 351636305)
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
54
-
-
33646034316
-
Activation of IKK by TNFα requires site-specific ubiquitination of RIP1 and pol yubiquitin binding by NEMO
-
Ea, C. K., Deng, L., Xia, Z. P., Pineda, G. & Chen, Z. J. Activation of IKK by TNFα requires site-specific ubiquitination of RIP1 and pol yubiquitin binding by NEMO. Mol. Cell 22, 245-257 (2006).
-
(2006)
Mol. Cell
, vol.22
, pp. 245-257
-
-
Ea, C.K.1
Deng, L.2
Xia, Z.P.3
Pineda, G.4
Chen, Z.J.5
-
55
-
-
79952623655
-
CIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
-
Vanlangenakker, N. et al. cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production. Cell Death Differ. 18, 656-665 (2011).
-
(2011)
Cell Death Differ.
, vol.18
, pp. 656-665
-
-
Vanlangenakker, N.1
-
56
-
-
79953282304
-
And RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling
-
Biton, S. & Ashkenazi, A. NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling. Cell 145, 92-103 (2011).
-
(2011)
Cell
, vol.145
, pp. 92-103
-
-
Biton, S.1
Nemo, A.A.2
-
57
-
-
79959539790
-
Ubiquitylation in apoptosis: A post-translational he edge of life and death
-
Vucic, D., Dixit, V. M. & Wertz, I. E. Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death. Nature Rev. Mol. Cell Biol. 12, 439-452 (2011).
-
(2011)
Nature Rev. Mol. Cell Biol.
, vol.12
, pp. 439-452
-
-
Vucic, D.1
Dixit, V.M.2
Wertz, I.E.3
-
58
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
DOI 10.1016/S0092-8674(03)00521-X
-
Micheau, O. & Tschopp, J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114, 181-190 (2003). (Pubitemid 36936912)
-
(2003)
Cell
, vol.114
, Issue.2
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
59
-
-
4544288868
-
Activation of caspases-8 and -10 by FLIPL
-
Boatright, K. M., Deis, C., Denault, J. B., Sutherlin, D. P. & Salvesen, G. S. Activation of caspases-8 and -10 by FLIPL. Biochem. J. 382, 651-657 (2004).
-
(2004)
Biochem. J.
, vol.382
, pp. 651-657
-
-
Boatright K, M.1
Deis, C.2
Denault, J.B.3
Sutherlin, D.P.4
Salvesen, G.S.5
-
60
-
-
0037160117
-
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex
-
DOI 10.1074/jbc.M206882200
-
Micheau, O. et al. The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J. Biol. Chem. 277 , 45162-45171 (2002). (Pubitemid 36159119)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.47
, pp. 45162-45171
-
-
Micheau, O.1
Thome, M.2
Schneider, P.3
Holler, N.4
Tschopp, J.5
Nicholson, D.W.6
Briand, C.7
Grutter, M.G.8
-
61
-
-
77952784381
-
Inducible dimerization and inducible cleav age reveal a requirement for both processes in caspase-8 activation
-
Oberst, A. et al. Inducible dimerization and inducible cleav age reveal a requirement for both processes in caspase-8 activation. J. Biol. Chem. 285, 16632- 16642 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 16632-16642
-
-
Oberst, A.1
-
62
-
-
78751487532
-
FLIPL induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity
-
Pop, C. et al. FLIPL induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity. Biochem. J. 433 , 447-457 (2011).
-
(2011)
Biochem. J.
, vol.433
, pp. 447-457
-
-
Pop, C.1
-
63
-
-
0347065342
-
A Role for Tumor Necrosis Factor Receptor-2 and Receptor-interacting Protein in Programmed Necrosis and Antiviral Responses
-
DOI 10.1074/jbc.M305633200
-
Chan, F. K. et al. A role for tumor ne crosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. J. Biol. Chem. 278 , 51613-51621 (2003). (Pubitemid 38020406)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.51
, pp. 51613-51621
-
-
Chan, F.K.-M.1
Shisler, J.2
Bixby, J.G.3
Felices, M.4
Zheng, L.5
Appel, M.6
Orenstein, J.7
Moss, B.8
Lenardo, M.J.9
-
64
-
-
0033214236
-
Cleavage of the death domain kinase RIP by Caspase-8 prompts TNF-induced apoptosis
-
DOI 10.1101/gad.13.19.2514
-
Lin, Y., Devin, A., Rodriguez, Y. & Liu, Z. G. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev. 13, 2514-2526 (1999). (Pubitemid 29489643)
-
(1999)
Genes and Development
, vol.13
, Issue.19
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.-G.4
-
65
-
-
80053087284
-
Complementary roles of FADD and RIPK3 in T cell homeostasis and antiviral immunity
-
Lu, J. V. et al. Complementary roles of FADD and RIPK3 in T cell homeostasis and antiviral immunity. Proc. Natl Acad. Sci. USA 108, 15312-15317 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 15312-15317
-
-
Lu, J.V.1
-
66
-
-
34548437549
-
Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain
-
DOI 10.1016/j.cellsig.2007.05.016, PII S089865680700157X
-
Feng, S. et al. Cleavage of RIP3 inactivates its cas pase-independent apoptosis pathway by removal of kinase domain. Cell. Signal. 19, 2056-2067 (2007). (Pubitemid 47353808)
-
(2007)
Cellular Signalling
, vol.19
, Issue.10
, pp. 2056-2067
-
-
Feng, S.1
Yang, Y.2
Mei, Y.3
Ma, L.4
Zhu, D.-e.5
Hoti, N.6
Castanares, M.7
Wu, M.8
-
67
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
O'Donnell, M. A. et al. Caspase 8 inhibits programmed necrosis by processing CYLD. Nature Cell Biol. 13 , 1437-1442 (2011).
-
(2011)
Nature Cell Biol.
, vol.13
, pp. 1437-1442
-
-
O'Donnell, M.A.1
-
68
-
-
79955484750
-
Mechanisms of necroptosis in T cells
-
Ch'en, I. L., Tsau, J. S., Molkentin, J. D., Komatsu, M. & Hedrick, S. M. Mechanisms of necroptosis in T cells. J. Exp. Med. 208, 633-641 (2011).
-
(2011)
J. Exp. Med.
, pp. 208633-641
-
-
Ch'En, I.L.1
Tsau, J.S.2
Molkentin, J.D.3
Komatsu, M.4
Hedrick, S.M.5
-
69
-
-
77953786510
-
Intertwined pathways of programmed cell death in immunity
-
Hedrick, S. M., Ch'en, I. L. & Alves, B. N. Intertwined pathways of programmed cell death in immunity. Immunol. Rev. 236, 41-53 (2010).
-
(2010)
Immunol. Rev.
, vol.236
, pp. 41-53
-
-
Hedrick, S.M.1
Ch'En, I.L.2
Alves, B.N.3
-
70
-
-
56249132503
-
Antigen-mediated T cell expansion regulated by parallel pathways of death
-
Ch'en, I. L. et al. Antigen-mediated T cell expansion regulated by parallel pathways of death. Proc. Natl Acad. Sci. USA 105 , 17463-17468 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 17463-17468
-
-
Ch'En, I.L.1
-
71
-
-
0036707522
-
CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-κB activation
-
Gaide, O. et al. CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-κB activation. Nature Immunol. 3, 836-843 (2002).
-
(2002)
Nature Immunol.
, vol.3
, pp. 836-843
-
-
Gaide, O.1
-
72
-
-
0345374583
-
Regulation of NF-κB-Dependent Lymphocyte Activation and Development by Paracaspase
-
DOI 10.1126/science.1090769
-
Ruefli-Brasse, A. A., French, D. M. & Dixit, V. M. Regulation of NF-? B-dependent lymphocyte activation and development by paracaspase. Science 302, 1581-1584 (2003). (Pubitemid 37475705)
-
(2003)
Science
, vol.302
, Issue.5650
, pp. 1581-1584
-
-
Ruefli-Brasse, A.A.1
French, D.M.2
Dixit, V.M.3
-
73
-
-
17744386318
-
Bcl10 is a positive regulator of antigen receptor-induced activation of NF-κB and neural tube closure
-
DOI 10.1016/S0092-8674(01)00189-1
-
Ruland, J. et al. Bcl10 is a positive regulator of antigen receptor-induced activation of NF-κB and neural tube closure. Cell 104, 33-42 (2001). (Pubitemid 32144970)
-
(2001)
Cell
, vol.104
, Issue.1
, pp. 33-42
-
-
Ruland, J.1
Duncan, G.S.2
Elia, A.3
Del Barco Barrantes, I.4
Nguyen, L.5
Plyte, S.6
Millar, D.G.7
Bouchard, D.8
Wakeham, A.9
Ohashi, P.S.10
Mak, T.W.11
-
74
-
-
48349125069
-
The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation
-
Kawadler, H., Gantz, M. A., Riley, J. L. & Yang, X. The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation. Mol. Cell 31, 415-421 (2008).
-
(2008)
Mol. Cell
, vol.31
, pp. 415-421
-
-
Kawadler, H.1
Gantz, M.A.2
Riley, J.L.3
Yang, X.4
-
75
-
-
34547111577
-
L associate in lipid rafts with NF-κB adaptors during T cell activation
-
DOI 10.1074/jbc.M610610200
-
Misra, R. S. et al. Caspase-8 and c-FLIPL associate in lipid rafts with NF-κB adaptors during T cell activation. J. Biol. Chem. 282, 19365-19374 (2007). (Pubitemid 47100110)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.27
, pp. 19365-19374
-
-
Misra, R.S.1
Russell, J.Q.2
Koenig, A.3
Hinshaw-Makepeace, J.A.4
Wen, R.5
Wang, D.6
Huo, H.7
Littman, D.R.8
Ferch, U.9
Ruland, J.10
Thome, M.11
Budd, R.C.12
-
76
-
-
33747611467
-
Delineation of the cell-extrinsic apoptosis pathway in the zebrafish
-
DOI 10.1038/sj.cdd.4402015, PII 4402015
-
Eimon P.M., et al. Delineation of the cell-extrinsic apoptosis pathway in the zebrafish Cell Death Differ. 2006 13 1619-1630 (Pubitemid 44390850)
-
(2006)
Cell Death and Differentiation
, vol.13
, Issue.10
, pp. 1619-1630
-
-
Eimon, P.M.1
Kratz, E.2
Varfolomeev, E.3
Hymowitz, S.G.4
Stern, H.5
Zha, J.6
Ashkenazi, A.7
-
77
-
-
0036850985
-
The Drosophila immune defense against Gram-negative infection requires the death protein dFADD
-
DOI 10.1016/S1074-7613(02)00454-5
-
Naitza, S. et al. The Drosophila immune defense against Gram-negative infection requires the death protein dFADD. Immunity 17, 575-581 (2002). (Pubitemid 35351503)
-
(2002)
Immunity
, vol.17
, Issue.5
, pp. 575-581
-
-
Naitza, S.1
Rosse, C.2
Kappler, C.3
Georgel, P.4
Belvin, M.5
Gubb, D.6
Camonis, J.7
Hoffmann, J.A.8
Reichhart, J.-M.9
-
78
-
-
0034305744
-
The Drosophila caspase Dredd is required to resist Gram-negative bacterial infection
-
Leulier, F., Rodriguez, A., Khush, R. S., Abrams, J. M. & Lemaitre, B. The Drosophila caspase Dredd is required to resist Gram-negative bacterial infection. EMBO Rep. 1 , 353-358 (2000).
-
(2000)
EMBO Rep.
, vol.1
, pp. 353-358
-
-
Leulier, F.1
Rodriguez, A.2
Khush, R.S.3
Abrams, J.M.4
Lemaitre, B.5
-
79
-
-
0842304221
-
Kinase RIP3 Is Dispensable for Normal NF-κBs, Signaling by the B-Cell and T-Cell Receptors, Tumor Necrosis Factor Receptor 1, and Toll-Like Receptors 2 and 4
-
DOI 10.1128/MCB.24.4.1464-1469.2004
-
Newton, K., Sun, X. & Dixit, V. M. Kinase RIP3 is dispensable for normal NF-κB signa ling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4. Mol. Cell. Biol. 24 , 1464-1469 (2004). (Pubitemid 38167070)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.4
, pp. 1464-1469
-
-
Newton, K.1
Sun, X.2
Dixit, V.M.3
-
80
-
-
77956715781
-
Going up in flames: Necrotic cell injury and inflammatory diseases
-
Challa, S. & Chan, F. K. Going up in flames: necrotic cell injury and inflammatory diseases. Cell. Mol. Life Sci. 67, 3241-3253 (2010).
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 3241-3253
-
-
Challa, S.1
Chan, F.K.2
-
81
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
DOI 10.1038/nature06013, PII NATURE06013
-
Takaoka, A. et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 448 , 501-505 (2007). (Pubitemid 47123520)
-
(2007)
Nature
, vol.448
, Issue.7152
, pp. 501-505
-
-
Takaoka, A.1
Wang, Z.2
Choi, M.K.3
Yanai, H.4
Negishi, H.5
Ban, T.6
Lu, Y.7
Miyagishi, M.8
Kodama, T.9
Honda, K.10
Ohba, Y.11
Taniguchi, T.12
-
82
-
-
58749100879
-
Receptor-interacting prot ein homotypic interaction motif-dependent control of NF-κB activation via the DNA-dependent activator of IFN regulatory factors
-
Kaiser, W. J., Upton, J. W. & Mocarski, E. S. Receptor-interacting prot ein homotypic interaction motif-dependent control of NF-κB activation via the DNA-dependent activator of IFN regulatory factors. J. Immunol. 181, 6427-6434 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 6427-6434
-
-
Kaiser, W.J.1
Upton, J.W.2
Mocarski, E.S.3
-
83
-
-
68249113997
-
DAI/ZBP1 recrui ts RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-κB
-
Rebsamen, M. et al. DAI/ZBP1 recrui ts RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-κB. EMBO Rep. 10, 916-922 (2009).
-
(2009)
EMBO Rep.
, vol.10
, pp. 916-922
-
-
Rebsamen, M.1
-
84
-
-
72849146138
-
Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1
-
DeFilippis, V. R., Alvarado, D., Sali, T., Rothenburg, S. & Fruh, K. Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1. J. Virol. 84 , 585-598 (2010).
-
(2010)
J. Virol.
, vol.84
, pp. 585-598
-
-
Defilippis, V.R.1
Alvarado, D.2
Sali, T.3
Rothenburg, S.4
Fruh, K.5
-
85
-
-
38949093002
-
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
-
DOI 10.1038/nature06537, PII NATURE06537
-
Ishii, K. J. et al. TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature 451, 725-729 (2008). (Pubitemid 351220566)
-
(2008)
Nature
, vol.451
, Issue.7179
, pp. 725-729
-
-
Ishii, K.J.1
Kawagoe, T.2
Koyama, S.3
Matsui, K.4
Kumar, H.5
Kawai, T.6
Uematsu, S.7
Takeuchi, O.8
Takeshita, F.9
Coban, C.10
Akira, S.11
-
86
-
-
77950499409
-
Viral strategies for the evasion of immunogenic cell death
-
Galluzzi, L. et al. Viral strategies for the evasion of immunogenic cell death. J. Intern. Med. 267, 526- 542 (2010).
-
(2010)
J. Intern. Med.
, vol.267
, pp. 526-542
-
-
Galluzzi, L.1
-
87
-
-
77958184901
-
Manipulation of host cell death pathways during microbial infections
-
Lamkanfi, M. & Dixit, V. M. Manipulation of host cell death pathways during microbial infections. Cell Host Microbe 8 , 44-54 (2010).
-
(2010)
Cell Host Microbe
, vol.8
, pp. 44-54
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
88
-
-
35648987280
-
Pathogen subversion of cell-intrinsic innate immunity
-
DOI 10.1038/ni1528, PII NI1528
-
Roy, C. R. & Mocarski, E. S. Pathogen subversion of cell-intrinsic innate immunity. Nature Immunol. 8, 1179-1187 (2007). (Pubitemid 350019233)
-
(2007)
Nature Immunology
, vol.8
, Issue.11
, pp. 1179-1187
-
-
Roy, C.R.1
Mocarski, E.S.2
-
89
-
-
0032482169
-
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
-
DOI 10.1084/jem.187.9.1477
-
Vercammen, D. et al. Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J. Exp. Med. 187, 1477-1485 (1998). (Pubitemid 28215406)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.9
, pp. 1477-1485
-
-
Vercammen, D.1
Beyaert, R.2
Denecker, G.3
Goossens, V.4
Van Loo, G.5
Declercq, W.6
Grooten, J.7
Fiers, W.8
Vandenabeele, P.9
-
90
-
-
0026344133
-
Prevention of apoptosis by a baculovirus gene during infection of insect cells
-
Clem, R. J., Fechheimer, M. & Miller, L. K. Prevention of apoptosis by a baculovirus gene during infection of insect cells. Science 254, 1388-1390 (1991). (Pubitemid 21917477)
-
(1991)
Science
, vol.254
, Issue.5036
, pp. 1388-1390
-
-
Clem, R.J.1
Fechheimer, M.2
Miller, L.K.3
-
91
-
-
0032489389
-
Interaction of the adenovirus 14.7-kDa protein with FLICE inhibits Fas ligand-induced apoptosis
-
DOI 10.1074/jbc.273.10.5815
-
Chen, P., Tian, J., Kovesdi, I. & Bruder, J. T. Interaction of the adenovirus 14.7-kDa protein with FLICE inhibits Fas ligand-induced apoptosis. J. Biol. Chem. 273, 5815-5820 (1998). (Pubitemid 28124058)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.10
, pp. 5815-5820
-
-
Chen, P.1
Tian, J.2
Kovesdi, I.3
Bruder, J.T.4
-
92
-
-
29144495592
-
Near death experiences: Poxvirus regulation of apoptotic death
-
DOI 10.1016/j.virol.2005.09.032, PII S004268220500591X
-
Taylor J.M., Barry M. Near death experiences: Poxvirus regulation of apoptotic death Virology 2006). (Pubitemid 41814458)
-
(2006)
Virology
, vol.344
, Issue.1
, pp. 139-150
-
-
Taylor, J.M.1
Barry, M.2
-
93
-
-
0141893999
-
Inhibition of ap optosis by the ?-herpesviruses
-
Lagunoff, M. & Carroll, P. A. Inhibition of ap optosis by the ?-herpesviruses. Int. Rev. Immunol. 22 , 373-399 (2003).
-
(2003)
Int. Rev. Immunol.
, vol.22
, pp. 373-399
-
-
Lagunoff, M.1
Carroll, P.A.2
-
94
-
-
48849084220
-
Control of apoptosis by human cytomegalovirus
-
McCormick, A. L. Control of apoptosis by human cytomegalovirus. Curr. Top. Microbiol. Immunol. 325 , 281-295 (2008).
-
(2008)
Curr. Top. Microbiol. Immunol.
, vol.325
, pp. 281-295
-
-
McCormick, A.L.1
-
95
-
-
0033861807
-
Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: Novel mechanism for killing virus-infected cells
-
DOI 10.1128/JVI.74.16.7470-7477.2000
-
Li, M. & Beg, A. A. Induction of necrotic-like cell death by tumor necrosis factor α and caspase inhibitors: novel mechanism for killing virus-infected cells. J. Virol. 74, 7470-7477 (2000). (Pubitemid 30613092)
-
(2000)
Journal of Virology
, vol.74
, Issue.16
, pp. 7470-7477
-
-
Li, M.1
Beg, A.A.2
-
96
-
-
84989895651
-
-
(eds Arvin, A. et al. (Cambridge Univ. Press, Cambridge, UK
-
Mocarski, E. S. in Human Herpesviruses: Biology, Therapy and Immunoprophylaxis (eds Arvin, A. et al.) 204-230 (Cambridge Univ. Press, Cambridge, UK, 2007).
-
(2007)
Human Herpesviruses: Biology, Therapy and Immunoprophylaxis
, pp. 204-230
-
-
Mocarski, E.S.1
-
97
-
-
39749174410
-
Dominant-negative FADD rescues the in vivo fitness of a cytomegalovirus lacking an antiapoptotic viral gene
-
DOI 10.1128/JVI.01803-07
-
Cicin-Sain, L. et al. Dominant-negative FADD rescues the in vivo fitness of a cytomegalovirus lacking an antiapoptotic viral gene. J. Virol. 82 , 2056-2064 (2008). (Pubitemid 351293508)
-
(2008)
Journal of Virology
, vol.82
, Issue.5
, pp. 2056-2064
-
-
Cicin-Sain, L.1
Ruzsics, Z.2
Podlech, J.3
Bubic, I.4
Menard, C.5
Jonjic, S.6
Reddehase, M.J.7
Koszinowski, U.H.8
-
98
-
-
0034933686
-
A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activation
-
DOI 10.1073/pnas.141108798
-
Skaletskaya, A. et al. A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activation. Proc. Natl Acad. Sci. USA 98 , 7829-7834 (2001). (Pubitemid 32642646)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.14
, pp. 7829-7834
-
-
Skaletskaya, A.1
Bartle, L.M.2
Chittenden, T.3
McCormick, A.L.4
Mocarski, E.S.5
Goldmacher, V.S.6
-
99
-
-
79955043158
-
Inhibition of programmed cell death by cytomegaloviruses
-
Brune, W. Inhibition of programmed cell death by cytomegaloviruses. Virus Res. 157, 144-150 (2011).
-
(2011)
Virus Res.
, vol.157
, pp. 144-150
-
-
Brune, W.1
-
100
-
-
58249115007
-
Virally mediated inhibition of Bax in leukocytes promotes dissemination of murine cytomegalovirus
-
Manzur, M., Fleming, P., Huang, D. C., Degli-Esposti, M. A. & Andoniou, C. E. Virally mediated inhibition of Bax in leukocytes promotes dissemination of murine cytomegalovirus. Cell Death Differ. 16, 312-320 (2009).
-
(2009)
Cell Death Differ.
, vol.16
, pp. 312-320
-
-
Manzur, M.1
Fleming, P.2
Huang, D.C.3
Degli-Esposti, M.A.4
Andoniou, C.E.5
-
101
-
-
47749133767
-
Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent intera ction with RIP1
-
Upton, J. W., Kaiser, W. J. & Mocarski, E. S. Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent intera ction with RIP1. J. Biol. Chem. 283, 16966-16970 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 16966-16970
-
-
Upton, J.W.1
Kaiser, W.J.2
Mocarski, E.S.3
-
102
-
-
42949111649
-
Inhibition of proinflammatory and innate immune signaling pathways by a cytomegalovirus RIP1-interacting protein
-
DOI 10.1073/pnas.0800168105
-
Mack, C., Sickmann, A., Lembo, D. & Brune, W. Inhibition of proinflammatory and innate immune signaling pathways by a cytomegalov irus RIP1-interacting protein. Proc. Natl Acad. Sci. USA 105, 3094-3099 (2008). (Pubitemid 351723673)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.8
, pp. 3094-3099
-
-
Mack, C.1
Sickmann, A.2
Lembo, D.3
Brune, W.4
-
103
-
-
58149279459
-
Tinkering with a viral ribonucleotide reductase
-
Lembo, D. & Brune, W. Tinkering with a viral ribonucleotide reductase. Trends Biochem. Sci. 34 , 25-32 (2009).
-
(2009)
Trends Biochem. Sci.
, vol.34
, pp. 25-32
-
-
Lembo, D.1
Brune, W.2
-
104
-
-
0344982847
-
Differential function and expression of the viral inhibitor of caspase 8-induced apoptosis (vICA) and the viral mitochondria-localized inhibitor of apoptosis (vMIA) cell death suppressors conserved in primate and rodent cytomegaloviruses
-
DOI 10.1016/j.virol.2003.07.003
-
McCormick, A. L., Skaletskaya, A., Barry, P. A., Mocarski, E. S. & Goldmacher, V. S. Differential function and expression of the viral inhibitor of caspase 8-induced apoptosis (vICA) and the viral mitochondria-localized inhibitor of apoptosis (vMIA) cell death suppressors conserved in primate and rodent cytomegaloviruses. Virology 316, 221-233 (2003). (Pubitemid 37468526)
-
(2003)
Virology
, vol.316
, Issue.2
, pp. 221-233
-
-
McCormick, A.L.1
Skaletskaya, A.2
Barry, P.A.3
Mocarski, E.S.4
Goldmacher, V.S.5
-
105
-
-
77949423965
-
Antagonist ic coevolution accelerates molecular evolution
-
Paterson, S. et al. Antagonist ic coevolution accelerates molecular evolution. Nature 464, 275- 278 (2010).
-
(2010)
Nature
, vol.464
, pp. 275-278
-
-
Paterson, S.1
-
106
-
-
79954520197
-
Armed response: How dying cells influence T-cell functions
-
Ferguson, T. A., Choi, J. & Green, D. R. Armed response: how dying cells influence T-cell functions. I mmunol. Rev. 241, 77-88 (2011).
-
(2011)
I Mmunol. Rev.
, vol.241
, pp. 77-88
-
-
Ferguson, T.A.1
Choi, J.2
Green, D.R.3
-
107
-
-
0037066427
-
The danger model: A renewed sense of self
-
DOI 10.1126/science.1071059
-
Matzinger, P. The danger model: a renewed sense of self. Science 296 , 301-305 (2002). (Pubitemid 34303674)
-
(2002)
Science
, vol.296
, Issue.5566
, pp. 301-305
-
-
Matzinger, P.1
-
108
-
-
33748522053
-
Clearance of apoptotic and necrotic cells and its immunological consequences
-
DOI 10.1007/s10495-006-9527-8
-
Krysko, D. V., D'Herde, K. & Vandenabeele, P. Clearance of apoptotic and necrotic cells and its immunological consequences. Apoptosis 11 , 1709-1726 (2006). (Pubitemid 44371047)
-
(2006)
Apoptosis
, vol.11
, Issue.10
, pp. 1709-1726
-
-
Krysko, D.V.1
D'Herde, K.2
Vandenabeele, P.3
-
109
-
-
60149085396
-
The many roles of FAS receptor signaling in the immune system
-
Strasser, A., Jost, P. J. & Nagata, S. The many roles of FAS receptor signaling in the immune system. Immunity 30, 180-192 (2009).
-
(2009)
Immunity
, vol.30
, pp. 180-192
-
-
Strasser, A.1
Jost, P.J.2
Nagata, S.3
-
110
-
-
0026568919
-
Lymphoproliferati on disorder in mice explained by defects in Fas antigen that mediates apoptosis
-
Watanabe-Fukunaga, R., Brannan, C. I., Copeland, N. G., Jenkins, N. A. & Nagata, S. Lymphoproliferati on disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356, 314-317 (1992).
-
(1992)
Nature
, vol.356
, pp. 314-317
-
-
Watanabe-Fukunaga, R.1
Brannan, C.I.2
Copeland, N.G.3
Jenkins, N.A.4
Nagata, S.5
-
111
-
-
0028980902
-
And Fas ligand: Lpr and gld mutations
-
Nagata, S. & Suda, T. Fas and Fas ligand: lpr and gld mutations. Immunol. Today 16, 39-43 (1995).
-
(1995)
Immunol. Today
, vol.16
, pp. 39-43
-
-
Nagata, S.1
Fas, S.T.2
-
112
-
-
25144480009
-
Caspase-8 deficiency in T cells leads to a lethal lymphoinfiltrative immune disorder
-
DOI 10.1084/jem.20050683
-
Salmena, L. & Hakem, R. Caspase-8 deficiency in T cells leads to a lethal lymphoinfiltrative immune disorder. J. Exp. Med. 202, 727-732 (2005). (Pubitemid 41345961)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.6
, pp. 727-732
-
-
Salmena, L.1
Hakem, R.2
-
113
-
-
18544383460
-
Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency
-
Chun, H. J. et al. Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency. Nature 419 , 395-399 (2002).
-
(2002)
Nature
, vol.419
, pp. 395-399
-
-
Chun, H.J.1
-
114
-
-
0033538475
-
Inherited human caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II
-
DOI 10.1016/S0092-8674(00)80605-4
-
Wang, J. et al. Inherited human caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II. Cell 98 , 47-58 (1999). (Pubitemid 29331195)
-
(1999)
Cell
, vol.98
, Issue.1
, pp. 47-58
-
-
Wang, J.1
Zheng, L.2
Lobito, A.3
Chan, F.K.-M.4
Dale, J.5
Sneller, M.6
Yao, X.7
Puck, J.M.8
Straus, S.E.9
Lenardo, M.J.10
-
115
-
-
79251534357
-
FADD deficiency impairs early hematopoiesis in the bone marrow
-
Rosenberg, S., Zhang, H. & Zhang, J. FADD deficiency impairs early hematopoiesis in the bone marrow. J. Immunol. 186, 203-213 (2011).
-
(2011)
J. Immunol.
, vol.186
, pp. 203-213
-
-
Rosenberg, S.1
Zhang, H.2
Zhang, J.3
-
116
-
-
24744459035
-
Cutting edge: Innate immunity conferred by B cells is regulated by caspase-8
-
Beisner, D. R., Ch'en, I. L., Kolla, R. V., Hoffmann, A. & Hedr ick, S. M. Cutting edge: innate immunity conferred by B cells is regulated by caspase-8. J. Immunol. 175 , 3469-3473 (2005). (Pubitemid 41292003)
-
(2005)
Journal of Immunology
, vol.175
, Issue.6
, pp. 3469-3473
-
-
Beisner, D.R.1
Ch'en, I.L.2
Kolla, R.V.3
Hoffmann, A.4
Hedrick, S.M.5
-
117
-
-
33646879040
-
The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells
-
Imtiyaz, H. Z. et al. The Fas-associated death domain protein is requ ired in apoptosis and TLR-induced proliferative responses in B cells. J. Immunol. 176, 6852-6861 (2006). (Pubitemid 43787866)
-
(2006)
Journal of Immunology
, vol.176
, Issue.11
, pp. 6852-6861
-
-
Imtiyaz, H.Z.1
Rosenberg, S.2
Zhang, Y.3
Rahman, Z.S.M.4
Hou, Y.-J.5
Manser, T.6
Zhang, J.7
-
118
-
-
34147165459
-
Essential role for caspase-8 in toll-like receptors and NFκB signaling
-
DOI 10.1074/jbc.M606721200
-
Lemmers, B. et al. Essential role for caspase-8 in Toll-like receptors and NF?B signaling. J. Biol. Chem. 282, 7416-7423 (2007). (Pubitemid 47093691)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.10
, pp. 7416-7423
-
-
Lemmers, B.1
Salmena, L.2
Bidere, N.3
Su, H.4
Matysiak-Zablocki, E.5
Murakami, K.6
Ohashi, P.S.7
Jurisicova, A.8
Lenardo, M.9
Hakem, R.10
Hakem, A.11
-
119
-
-
70350484946
-
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease
-
Kovalenko, A. et al. Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J. Exp. Med. 206 , 2161-2177 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2161-2177
-
-
Kovalenko, A.1
-
120
-
-
63649143438
-
Dynamic expression of epidermal caspase 8 simulates a wound healing response
-
Lee, P. et al. Dynamic expression of epidermal caspase 8 simulates a wound healing response. Nature 458, 519-523 (2009).
-
(2009)
Nature
, vol.458
, pp. 519-523
-
-
Lee, P.1
-
121
-
-
78650667554
-
Development of atopic d ermatitis-like skin disease from the chronic loss of epidermal caspase-8
-
Li, C. et al. Development of atopic d ermatitis-like skin disease from the chronic loss of epidermal caspase-8. Proc. Natl Acad. Sci. USA 107, 22249- 22254 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 22249-22254
-
-
Li, C.1
-
122
-
-
34247361535
-
Role of caspase-8 in hepatocyte response to infection and injury in mice
-
DOI 10.1002/hep.21495
-
Ben Moshe, T. et al. R ole of caspase-8 in hepatocyte response to infection and injury in mice. Hepatology 45, 1014-1024 (2007). (Pubitemid 46631570)
-
(2007)
Hepatology
, vol.45
, Issue.4
, pp. 1014-1024
-
-
Ben Moshe, T.1
Barash, H.2
Kang, T.-B.3
Kim, J.-C.4
Kovalenko, A.5
Gross, E.6
Schuchmann, M.7
Abramovitch, R.8
Galun, E.9
Wallach, D.10
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