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Volumn 192, Issue 12, 2014, Pages 5548-5560

Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN SERINE THREONINE KINASE; RECEPTOR INTERACTING SERINE THREONINE KINASE 1; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

EID: 84902127968     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400122     Document Type: Article
Times cited : (45)

References (52)
  • 1
    • 68149139457 scopus 로고    scopus 로고
    • BH3-only proteins in rheumatoid arthritis: Potential targets for therapeutic intervention
    • Hutcheson, J., and H. Perlman. 2008. BH3-only proteins in rheumatoid arthritis: potential targets for therapeutic intervention. Oncogene 27(Suppl. 1):S168-S175.
    • (2008) Oncogene , vol.27 , Issue.SUPPL. 1
    • Hutcheson, J.1    Perlman, H.2
  • 4
    • 17844361968 scopus 로고    scopus 로고
    • Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation
    • Dohrman, A., T. Kataoka, S. Cuenin, J. Q. Russell, J. Tschopp, and R. C. Budd. 2005. Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation. J. Immunol. 174:5270-5278.
    • (2005) J. Immunol. , vol.174 , pp. 5270-5278
    • Dohrman, A.1    Kataoka, T.2    Cuenin, S.3    Russell, J.Q.4    Tschopp, J.5    Budd, R.C.6
  • 5
    • 79952770123 scopus 로고    scopus 로고
    • RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein
    • Rajput, A., A. Kovalenko, K. Bogdanov, S. H. Yang, T. B. Kang, J. C. Kim, J. Du, and D. Wallach. 2011. RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein. Immunity 34:340-351.
    • (2011) Immunity , vol.34 , pp. 340-351
    • Rajput, A.1    Kovalenko, A.2    Bogdanov, K.3    Yang, S.H.4    Kang, T.B.5    Kim, J.C.6    Du, J.7    Wallach, D.8
  • 7
    • 0034646478 scopus 로고    scopus 로고
    • Activation of NF-kappaB by FADD, Casper, and caspase-8
    • Hu, W. H., H. Johnson, and H. B. Shu. 2000. Activation of NF-kappaB by FADD, Casper, and caspase-8. J. Biol. Chem. 275:10838-10844.
    • (2000) J. Biol. Chem. , vol.275 , pp. 10838-10844
    • Hu, W.H.1    Johnson, H.2    Shu, H.B.3
  • 8
    • 80054888589 scopus 로고    scopus 로고
    • It cuts both ways: Reconciling the dual roles of caspase 8 in cell death and survival
    • Oberst, A., and D. R. Green. 2011. It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival. Nat. Rev. Mol. Cell Biol. 12:757-763.
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 757-763
    • Oberst, A.1    Green, D.R.2
  • 9
    • 84856231635 scopus 로고    scopus 로고
    • Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways
    • Mocarski, E. S., J. W. Upton, and W. J. Kaiser. 2012. Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways. Nat. Rev. Immunol. 12:79-88.
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 79-88
    • Mocarski, E.S.1    Upton, J.W.2    Kaiser, W.J.3
  • 12
    • 44849085476 scopus 로고    scopus 로고
    • The innate immune system in SLE: Type I interferons and dendritic cells
    • Rönnblom, L., and V. Pascual. 2008. The innate immune system in SLE: type I interferons and dendritic cells. Lupus 17:394-399.
    • (2008) Lupus , vol.17 , pp. 394-399
    • Rönnblom, L.1    Pascual, V.2
  • 13
    • 80052989433 scopus 로고    scopus 로고
    • Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation
    • Sears, N., G. C. Sen, G. R. Stark, and S. Chattopadhyay. 2011. Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation. J. Biol. Chem. 286:33037-33044.
    • (2011) J. Biol. Chem. , vol.286 , pp. 33037-33044
    • Sears, N.1    Sen, G.C.2    Stark, G.R.3    Chattopadhyay, S.4
  • 16
    • 2542449195 scopus 로고    scopus 로고
    • T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis
    • Hao, Z., B. Hampel, H. Yagita, and K. Rajewsky. 2004. T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis. J. Exp. Med. 199:1355-1365.
    • (2004) J. Exp. Med. , vol.199 , pp. 1355-1365
    • Hao, Z.1    Hampel, B.2    Yagita, H.3    Rajewsky, K.4
  • 17
    • 60149085396 scopus 로고    scopus 로고
    • The many roles of FAS receptor signaling in the immune system
    • Strasser, A., P. J. Jost, and S. Nagata. 2009. The many roles of FAS receptor signaling in the immune system. Immunity 30:180-192.
    • (2009) Immunity , vol.30 , pp. 180-192
    • Strasser, A.1    Jost, P.J.2    Nagata, S.3
  • 20
    • 33644502594 scopus 로고    scopus 로고
    • Dendritic cell apoptosis in the maintenance of immune tolerance
    • Chen, M., Y. H. Wang, Y. Wang, L. Huang, H. Sandoval, Y. J. Liu, and J. Wang. 2006. Dendritic cell apoptosis in the maintenance of immune tolerance. Science 311:1160-1164.
    • (2006) Science , vol.311 , pp. 1160-1164
    • Chen, M.1    Wang, Y.H.2    Wang, Y.3    Huang, L.4    Sandoval, H.5    Liu, Y.J.6    Wang, J.7
  • 21
    • 24744459035 scopus 로고    scopus 로고
    • Cutting edge: Innate immunity conferred by B cells is regulated by caspase-8
    • Beisner, D. R., I. L. Ch'en, R. V. Kolla, A. Hoffmann, and S. M. Hedrick. 2005. Cutting edge: innate immunity conferred by B cells is regulated by caspase-8. J. Immunol. 175:3469-3473.
    • (2005) J. Immunol. , vol.175 , pp. 3469-3473
    • Beisner, D.R.1    Ch'en, I.L.2    Kolla, R.V.3    Hoffmann, A.4    Hedrick, S.M.5
  • 24
    • 84858794257 scopus 로고    scopus 로고
    • A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment
    • Rose, S., A. Misharin, and H. Perlman. 2012. A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment. Cytometry A 81:343-350.
    • (2012) Cytometry A , vol.81 , pp. 343-350
    • Rose, S.1    Misharin, A.2    Perlman, H.3
  • 25
    • 0032960197 scopus 로고    scopus 로고
    • Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage
    • Labeur, M. S., B. Roters, B. Pers, A. Mehling, T. A. Luger, T. Schwarz, and S. Grabbe. 1999. Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage. J. Immunol. 162:168-175.
    • (1999) J. Immunol. , vol.162 , pp. 168-175
    • Labeur, M.S.1    Roters, B.2    Pers, B.3    Mehling, A.4    Luger, T.A.5    Schwarz, T.6    Grabbe, S.7
  • 27
    • 0033571320 scopus 로고    scopus 로고
    • Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway
    • Ashany, D., A. Savir, N. Bhardwaj, and K. B. Elkon. 1999. Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway. J. Immunol. 163:5303-5311.
    • (1999) J. Immunol. , vol.163 , pp. 5303-5311
    • Ashany, D.1    Savir, A.2    Bhardwaj, N.3    Elkon, K.B.4
  • 28
    • 0344737674 scopus 로고    scopus 로고
    • Fas ligation induces IL-1beta-dependent maturation and IL-1beta-independent survival of dendritic cells: Different roles of ERK and NF-kappaB signaling pathways
    • Guo, Z., M. Zhang, H. An, W. Chen, S. Liu, J. Guo, Y. Yu, and X. Cao. 2003. Fas ligation induces IL-1beta-dependent maturation and IL-1beta-independent survival of dendritic cells: different roles of ERK and NF-kappaB signaling pathways. Blood 102:4441-4447.
    • (2003) Blood , vol.102 , pp. 4441-4447
    • Guo, Z.1    Zhang, M.2    An, H.3    Chen, W.4    Liu, S.5    Guo, J.6    Yu, Y.7    Cao, X.8
  • 29
    • 84872764927 scopus 로고    scopus 로고
    • Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome
    • Kang, T. B., S. H. Yang, B. Toth, A. Kovalenko, and D. Wallach. 2013. Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity 38:27-40.
    • (2013) Immunity , vol.38 , pp. 27-40
    • Kang, T.B.1    Yang, S.H.2    Toth, B.3    Kovalenko, A.4    Wallach, D.5
  • 30
    • 0025875259 scopus 로고
    • Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease
    • Cohen, P. L., and R. A. Eisenberg. 1991. Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu. Rev. Immunol. 9:243-269.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 243-269
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 32
    • 80054927213 scopus 로고    scopus 로고
    • Microbiota and autoimmune disease: The hosted self
    • Mathis, D., and C. Benoist. 2011. Microbiota and autoimmune disease: the hosted self. Cell Host Microbe 10:297-301.
    • (2011) Cell Host Microbe , vol.10 , pp. 297-301
    • Mathis, D.1    Benoist, C.2
  • 34
    • 84896500701 scopus 로고    scopus 로고
    • Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1b in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway
    • Shenderov, K., N. Riteau, R. Yip, K. D. Mayer-Barber, S. Oland, S. Hieny, P. Fitzgerald, A. Oberst, C. P. Dillon, D. R. Green, et al. 2014. Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1b in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway. J. Immunol. 192:2029-2033.
    • (2014) J. Immunol. , vol.192 , pp. 2029-2033
    • Shenderov, K.1    Riteau, N.2    Yip, R.3    Mayer-Barber, K.D.4    Oland, S.5    Hieny, S.6    Fitzgerald, P.7    Oberst, A.8    Dillon, C.P.9    Green, D.R.10
  • 35
    • 84866735326 scopus 로고    scopus 로고
    • TLR7 and TLR9 in SLE: When sensing self goes wrong
    • Celhar, T., R. Magalhães, and A. M. Fairhurst. 2012. TLR7 and TLR9 in SLE: when sensing self goes wrong. Immunol. Res. 53:58-77.
    • (2012) Immunol. Res. , vol.53 , pp. 58-77
    • Celhar, T.1    Magalhães, R.2    Fairhurst, A.M.3
  • 36
    • 58049209834 scopus 로고    scopus 로고
    • Inflammatory signals in dendritic cell activation and the induction of adaptive immunity
    • Joffre, O., M. A. Nolte, R. Spörri, and C. Reis E Sousa. 2009. Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol. Rev. 227:234-247.
    • (2009) Immunol. Rev. , vol.227 , pp. 234-247
    • Joffre, O.1    Nolte, M.A.2    Spörri, R.3    Reis E Sousa, C.4
  • 37
    • 78650108453 scopus 로고    scopus 로고
    • Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage
    • Teichmann, L. L., M. L. Ols, M. Kashgarian, B. Reizis, D. H. Kaplan, and M. J. Shlomchik. 2010. Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage. Immunity 33:967-978.
    • (2010) Immunity , vol.33 , pp. 967-978
    • Teichmann, L.L.1    Ols, M.L.2    Kashgarian, M.3    Reizis, B.4    Kaplan, D.H.5    Shlomchik, M.J.6
  • 39
    • 84875547953 scopus 로고    scopus 로고
    • Signals via the adaptor MyD88 in B cells and DCs make distinct and synergistic contributions to immune activation and tissue damage in lupus
    • Teichmann, L. L., D. Schenten, R. Medzhitov, M. Kashgarian, and M. J. Shlomchik. 2013. Signals via the adaptor MyD88 in B cells and DCs make distinct and synergistic contributions to immune activation and tissue damage in lupus. Immunity 38:528-540.
    • (2013) Immunity , vol.38 , pp. 528-540
    • Teichmann, L.L.1    Schenten, D.2    Medzhitov, R.3    Kashgarian, M.4    Shlomchik, M.J.5
  • 40
    • 41949117115 scopus 로고    scopus 로고
    • Dynamic regulation of neutrophil survival through tyrosine phosphorylation or dephosphorylation of caspase-8
    • Jia, S. H., J. Parodo, A. Kapus, O. D. Rotstein, and J. C. Marshall. 2008. Dynamic regulation of neutrophil survival through tyrosine phosphorylation or dephosphorylation of caspase-8. J. Biol. Chem. 283:5402-5413.
    • (2008) J. Biol. Chem. , vol.283 , pp. 5402-5413
    • Jia, S.H.1    Parodo, J.2    Kapus, A.3    Rotstein, O.D.4    Marshall, J.C.5
  • 41
    • 84883338848 scopus 로고    scopus 로고
    • Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammation
    • Lamagna, C., P. Scapini, J. A. Van Ziffle, A. L. De Franco, and C. A. Lowell. 2013. Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammation. Proc. Natl. Acad. Sci. USA 110:E3311-E3320.
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110
    • Lamagna, C.1    Scapini, P.2    Van Ziffle, J.A.3    De Franco, A.L.4    Lowell, C.A.5
  • 42
    • 84879799191 scopus 로고    scopus 로고
    • Commensal microbiota are required for systemic inflammation triggered by necrotic dendritic cells
    • Young, J. A., T. H. He, B. Reizis, and A. Winoto. 2013. Commensal microbiota are required for systemic inflammation triggered by necrotic dendritic cells. Cell. Rep. 3:1932-1944.
    • (2013) Cell. Rep. , vol.3 , pp. 1932-1944
    • Young, J.A.1    He, T.H.2    Reizis, B.3    Winoto, A.4
  • 44
    • 77955450861 scopus 로고    scopus 로고
    • IRF-3 and Bax: A deadly affair
    • Chattopadhyay, S., and G. C. Sen. 2010. IRF-3 and Bax: a deadly affair. Cell Cycle 9:2479-2480.
    • (2010) Cell Cycle , vol.9 , pp. 2479-2480
    • Chattopadhyay, S.1    Sen, G.C.2
  • 45
    • 34347244891 scopus 로고    scopus 로고
    • The IRF family, revisited
    • Paun, A., and P. M. Pitha. 2007. The IRF family, revisited. Biochimie 89:744-753.
    • (2007) Biochimie , vol.89 , pp. 744-753
    • Paun, A.1    Pitha, P.M.2
  • 47
    • 77649334441 scopus 로고    scopus 로고
    • Dendritic cell function in lupus: Independent contributors or victims of aberrant immune regulation
    • Kis-Toth, K., and G. C. Tsokos. 2010. Dendritic cell function in lupus: Independent contributors or victims of aberrant immune regulation. Autoimmunity 43:121-130.
    • (2010) Autoimmunity , vol.43 , pp. 121-130
    • Kis-Toth, K.1    Tsokos, G.C.2
  • 48
    • 34548335243 scopus 로고    scopus 로고
    • Dendritic cells and the immunopathogenesis of systemic lupus erythematosus
    • Monrad, S., and M. J. Kaplan. 2007. Dendritic cells and the immunopathogenesis of systemic lupus erythematosus. Immunol. Res. 37:135-145.
    • (2007) Immunol. Res. , vol.37 , pp. 135-145
    • Monrad, S.1    Kaplan, M.J.2
  • 49
    • 84866533031 scopus 로고    scopus 로고
    • Distinct roles of myeloid and plasmacytoid dendritic cells in systemic lupus erythematosus
    • Chan, V. S., Y. J. Nie, N. Shen, S. Yan, M. Y. Mok, and C. S. Lau. 2012. Distinct roles of myeloid and plasmacytoid dendritic cells in systemic lupus erythematosus. Autoimmun. Rev. 11:890-897.
    • (2012) Autoimmun. Rev. , vol.11 , pp. 890-897
    • Chan, V.S.1    Nie, Y.J.2    Shen, N.3    Yan, S.4    Mok, M.Y.5    Lau, C.S.6
  • 51
    • 33749622448 scopus 로고    scopus 로고
    • Monocyte-derived dendritic cells over-express CD86 in patients with systemic lupus erythematosus
    • Decker, P., I. Kötter, R. Klein, B. Berner, and H. G. Rammensee. 2006. Monocyte-derived dendritic cells over-express CD86 in patients with systemic lupus erythematosus. Rheumatology (Oxford) 45:1087-1095.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 1087-1095
    • Decker, P.1    Kötter, I.2    Klein, R.3    Berner, B.4    Rammensee, H.G.5
  • 52
    • 82655181636 scopus 로고    scopus 로고
    • Animal models of molecular pathology systemic lupus erythematosus
    • Sang, A., Y. Yin, Y. Y. Zheng, and L. Morel. 2012. Animal models of molecular pathology systemic lupus erythematosus. Prog. Mol. Biol. Transl. Sci. 105:321-370
    • (2012) Prog. Mol. Biol. Transl. Sci. , vol.105 , pp. 321-370
    • Sang, A.1    Yin, Y.2    Zheng, Y.Y.3    Morel, L.4


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