Kinetic investigations of the role of factor inhibiting hypoxia-inducible factor (FIH) as an oxygen sensor

Journal of Biological Chemistry

Volumn 290, Issue 32, 2015, Pages 19726-19742

  Tarhonskaya, Hanna ^a   Hardy, Adam P ^a   Howe, Emily A ^a   Loik, Nikita D ^a,b   Kramer, Holger B ^a   McCullagh, James S O ^a   Schofield, Christopher J ^a   Flashman, Emily ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

KINETICS; SUBSTRATES;

ANKYRIN-REPEAT DOMAIN; BIOLOGICAL CAPACITY; HYPOXIA-INDUCIBLE FACTORS; HYPOXIC CONDITION; KINETIC INVESTIGATIONS; KINETIC PROPERTIES; MEDIATED TRANSCRIPTION; POST-TRANSLATIONAL MODIFICATIONS;

REACTION KINETICS;

ASPARAGINYL HYDROXYLASE; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR HYDROXYLASE; ISOENZYME; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; UNCLASSIFIED DRUG; ANKYRIN; EGLN1 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; HIF1AN PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE; MIXED FUNCTION OXIDASE; RECOMBINANT PROTEIN; REPRESSOR PROTEIN;

ARTICLE; CHEMICAL INTERACTION; CONTROLLED STUDY; ENZYME KINETICS; ENZYME SUBSTRATE; HYPOXIA; NONHUMAN; OXYGEN SENSING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; AMINO ACID SEQUENCE; ANIMAL; ANOXIA; BIOCATALYSIS; ESCHERICHIA COLI; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION;

ANIMALIA;

AMINO ACID SEQUENCE; ANIMALS; ANKYRINS; ANOXIA; BIOCATALYSIS; ESCHERICHIA COLI; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; KINETICS; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; OXYGEN; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 84939194122     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.653014     Document Type: Article

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