Factor inhibiting HIF (FIH) recognizes distinct molecular features within hypoxia-inducible factor-α (HIF-α) versus ankyrin repeat substrates

Journal of Biological Chemistry

Volumn 287, Issue 12, 2012, Pages 8769-8781

  Wilkins, Sarah E ^a   Karttunen, Sarah ^a   Hampton Smith, Rachel J ^a   Murchland, Iain ^a   Chapman Smith, Anne ^a   Peet, Daniel J ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; ANKYRIN-REPEAT DOMAIN; ASPARAGINE RESIDUE; CELL LYSATES; CHIMERIC SUBSTRATES; HIGH AFFINITY; HYPOXIA-INDUCIBLE FACTORS; IN-VIVO; MACROMOLECULAR CROWDING; MOLECULAR DETERMINANTS; MOLECULAR FEATURE; SUBSTRATE PROPERTIES; SUBSTRATE RECOGNITION;

AMINO ACIDS; HYDROXYLATION; TRANSCRIPTION FACTORS;

SUBSTRATES;

2 OXOGLUTARIC ACID; ANKYRIN; ASPARAGINE; FACTOR INHIBITING HIF; HYPOXIA INDUCIBLE FACTOR ALPHA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CELL LYSATE; CONTROLLED STUDY; HYDROXYLATION; IN VIVO STUDY; KINETICS; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; ANKYRIN REPEAT; HUMANS; HYDROXYLATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, KNOCKOUT; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTO-ONCOGENE PROTEINS; RECEPTOR, NOTCH1; RECEPTORS, NOTCH; REPRESSOR PROTEINS; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS;

EID: 84858605888     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.294678     Document Type: Article

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