Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel

Journal of Cell Science

Volumn 128, Issue 2, 2015, Pages 225-231

  Karttunen, Sarah ^a   Duffield, Michael ^a   Scrimgeour, Nathan R ^a   Squires, Lauren ^a   Lim, Wai Li ^a   Dallas, Mark L ^b,e   Scragg, Jason L ^b   Chicher, Johana ^c   Dave, Keyur A ^c   Whitelaw, Murray L ^a   Peers, Chris ^b   Gorman, Jeffrey J ^c   Gleadle, Jonathan M ^d   Rychkov, Grigori Y ^a   Peet, Daniel J ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^d FLINDERS UNIVERSITY   (Australia)

^e UNIVERSITY OF READING   (United Kingdom)

Author keywords

FIH; Hydroxylation; Hypoxia; TRPV3

Indexed keywords

ASPARAGINE; HIF1AN PROTEIN; OXYGEN; OXYGENASE; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 3; ANKYRIN; HIF1AN PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MIXED FUNCTION OXIDASE; PROTEIN BINDING; REPRESSOR PROTEIN; TRPV3 PROTEIN, HUMAN; VANILLOID RECEPTOR;

ARTICLE; CONTROLLED STUDY; CYTOPLASM; EMBRYO; HUMAN; HUMAN CELL; HYDROXYLATION; HYPOXIA; IN VITRO STUDY; MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; REGULATORY MECHANISM; AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; CELL HYPOXIA; GENETICS; HEK293 CELL LINE; METABOLISM;

AMINO ACID SEQUENCE; ANKYRIN REPEAT; CELL HYPOXIA; HEK293 CELLS; HUMANS; HYDROXYLATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MIXED FUNCTION OXYGENASES; MUTATION; OXYGEN; PROTEIN BINDING; REPRESSOR PROTEINS; TRPV CATION CHANNELS;

EID: 84921328285     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.158451     Document Type: Article

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