-
1
-
-
0014325451
-
The origin and kinetics of mononuclear phagocytes
-
van Furth R, Cohn ZA. The origin and kinetics of mononuclear phagocytes. J Exp Med (1968) 128:415-35. doi:10.1084/jem.128.3.415
-
(1968)
J Exp Med
, vol.128
, pp. 415-435
-
-
van Furth, R.1
Cohn, Z.A.2
-
2
-
-
76249095169
-
Development of monocytes, macrophages, and dendritic cells
-
Geissmann F, Manz MG, Jung S, Sieweke MH, Merad M, Ley K. Development of monocytes, macrophages, and dendritic cells. Science (2010) 327:656-61. doi:10.1126/science.1178331
-
(2010)
Science
, vol.327
, pp. 656-661
-
-
Geissmann, F.1
Manz, M.G.2
Jung, S.3
Sieweke, M.H.4
Merad, M.5
Ley, K.6
-
3
-
-
28544446111
-
Monocyte and macrophage heterogeneity
-
Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol (2005) 5:953-64. doi:10.1038/nri1733
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 953-964
-
-
Gordon, S.1
Taylor, P.R.2
-
4
-
-
30044434256
-
The mononuclear phagocyte system
-
Hume DA. The mononuclear phagocyte system. Curr Opin Immunol (2006) 18:49-53. doi:10.1016/j.coi.2005.11.008
-
(2006)
Curr Opin Immunol
, vol.18
, pp. 49-53
-
-
Hume, D.A.1
-
5
-
-
54449093241
-
Differentiation and heterogeneity in the mononuclear phagocyte system
-
Hume DA. Differentiation and heterogeneity in the mononuclear phagocyte system. Mucosal Immunol (2008) 1:432-41. doi:10.1038/mi.2008.36
-
(2008)
Mucosal Immunol
, vol.1
, pp. 432-441
-
-
Hume, D.A.1
-
6
-
-
84857618521
-
Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling
-
Hume DA, MacDonald KP. Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling. Blood (2012) 119:1810-20. doi:10.1182/blood-2011-09-379214
-
(2012)
Blood
, vol.119
, pp. 1810-1820
-
-
Hume, D.A.1
MacDonald, K.P.2
-
7
-
-
84876800337
-
Macrophage biology in development, homeostasis and disease
-
Wynn TA, Chawla A, Pollard JW. Macrophage biology in development, homeostasis and disease. Nature (2013) 496:445-55. doi:10.1038/nature12034
-
(2013)
Nature
, vol.496
, pp. 445-455
-
-
Wynn, T.A.1
Chawla, A.2
Pollard, J.W.3
-
8
-
-
84905093326
-
Homeostasis in the mononuclear phagocyte system
-
Jenkins SJ, Hume DA. Homeostasis in the mononuclear phagocyte system. Trends Immunol (2014) 35(8):358-67. doi:10.1016/j.it.2014.06.006
-
(2014)
Trends Immunol
, vol.35
, Issue.8
, pp. 358-367
-
-
Jenkins, S.J.1
Hume, D.A.2
-
9
-
-
78149360132
-
Fate mapping analysis reveals that adult microglia derive from primitive macrophages
-
Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science (2010) 330:841-5. doi:10.1126/science.1194637
-
(2010)
Science
, vol.330
, pp. 841-845
-
-
Ginhoux, F.1
Greter, M.2
Leboeuf, M.3
Nandi, S.4
See, P.5
Gokhan, S.6
-
10
-
-
73949147392
-
Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network
-
Chorro L, Sarde A, Li M, Woollard KJ, Chambon P, Malissen B, et al. Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network. J Exp Med (2009) 206:3089-100. doi:10.1084/jem.20091586
-
(2009)
J Exp Med
, vol.206
, pp. 3089-3100
-
-
Chorro, L.1
Sarde, A.2
Li, M.3
Woollard, K.J.4
Chambon, P.5
Malissen, B.6
-
11
-
-
84864298329
-
Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages
-
Hoeffel G, Wang Y, Greter M, See P, Teo P, Malleret B, et al. Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J Exp Med (2012) 209:1167-81. doi:10.1084/jem.20120340
-
(2012)
J Exp Med
, vol.209
, pp. 1167-1181
-
-
Hoeffel, G.1
Wang, Y.2
Greter, M.3
See, P.4
Teo, P.5
Malleret, B.6
-
12
-
-
84859508307
-
A lineage of myeloid cells independent of Myb and hematopoietic stem cells
-
Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, et al. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science (2012) 336:86-90. doi:10.1126/science.1219179
-
(2012)
Science
, vol.336
, pp. 86-90
-
-
Schulz, C.1
Gomez Perdiguero, E.2
Chorro, L.3
Szabo-Rogers, H.4
Cagnard, N.5
Kierdorf, K.6
-
13
-
-
84876775203
-
Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes
-
Hashimoto D, Chow A, Noizat C, Teo P, Beasley MB, Leboeuf M, et al. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity (2013) 38:792-804. doi:10.1016/j.immuni.2013.04.004
-
(2013)
Immunity
, vol.38
, pp. 792-804
-
-
Hashimoto, D.1
Chow, A.2
Noizat, C.3
Teo, P.4
Beasley, M.B.5
Leboeuf, M.6
-
14
-
-
84872765982
-
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis
-
Yona S, Kim KW, Wolf Y, Mildner A, Varol D, Breker M, et al. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity (2013) 38:79-91. doi:10.1016/j.immuni.2012.12.001
-
(2013)
Immunity
, vol.38
, pp. 79-91
-
-
Yona, S.1
Kim, K.W.2
Wolf, Y.3
Mildner, A.4
Varol, D.5
Breker, M.6
-
16
-
-
84861639667
-
The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1
-
Liu H, Leo C, Chen X, Wong BR, Williams LT, Lin H, et al. The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1. Biochim Biophys Acta (2012) 1824(7):938-45. doi:10.1016/j.bbapap.2012.04.012
-
(2012)
Biochim Biophys Acta
, vol.1824
, Issue.7
, pp. 938-945
-
-
Liu, H.1
Leo, C.2
Chen, X.3
Wong, B.R.4
Williams, L.T.5
Lin, H.6
-
17
-
-
84859407607
-
Structural basis for the dual recognition of helical cytokines IL-34 and CSF-1 by CSF-1R
-
Ma X, Lin WY, Chen Y, Stawicki S, Mukhyala K, Wu Y, et al. Structural basis for the dual recognition of helical cytokines IL-34 and CSF-1 by CSF-1R. Structure (2012) 20:676-87. doi:10.1016/j.str.2012.02.010
-
(2012)
Structure
, vol.20
, pp. 676-687
-
-
Ma, X.1
Lin, W.Y.2
Chen, Y.3
Stawicki, S.4
Mukhyala, K.5
Wu, Y.6
-
18
-
-
77952524264
-
Pivotal advance: avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products
-
Garceau V, Smith J, Paton IR, Davey M, Fares MA, Sester DP, et al. Pivotal advance: avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products. J Leukoc Biol (2010) 87:753-64. doi:10.1189/jlb.0909624
-
(2010)
J Leukoc Biol
, vol.87
, pp. 753-764
-
-
Garceau, V.1
Smith, J.2
Paton, I.R.3
Davey, M.4
Fares, M.A.5
Sester, D.P.6
-
19
-
-
84862122306
-
The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation
-
Nandi S, Gokhan S, Dai XM, Wei S, Enikolopov G, Lin H, et al. The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation. Dev Biol (2012) 367:100-13. doi:10.1016/j.ydbio.2012.03.026
-
(2012)
Dev Biol
, vol.367
, pp. 100-113
-
-
Nandi, S.1
Gokhan, S.2
Dai, X.M.3
Wei, S.4
Enikolopov, G.5
Lin, H.6
-
20
-
-
84885423625
-
IL-34 and CSF-1: similarities and differences
-
Nakamichi Y, Udagawa N, Takahashi N. IL-34 and CSF-1: similarities and differences. J Bone Miner Metab (2013) 31:486-95. doi:10.1007/s00774-013-0476-3
-
(2013)
J Bone Miner Metab
, vol.31
, pp. 486-495
-
-
Nakamichi, Y.1
Udagawa, N.2
Takahashi, N.3
-
21
-
-
78149462163
-
An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue-and tumor-associated macrophages but does not inhibit inflammation
-
MacDonald KP, Palmer JS, Cronau S, Seppanen E, Olver S, Raffelt NC, et al. An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue-and tumor-associated macrophages but does not inhibit inflammation. Blood (2010) 116:3955-63. doi:10.1182/blood-2010-02-266296
-
(2010)
Blood
, vol.116
, pp. 3955-3963
-
-
MacDonald, K.P.1
Palmer, J.S.2
Cronau, S.3
Seppanen, E.4
Olver, S.5
Raffelt, N.C.6
-
22
-
-
0037307026
-
A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse
-
Sasmono RT, Oceandy D, Pollard JW, Tong W, Pavli P, Wainwright BJ, et al. A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood (2003) 101:1155-63. doi:10.1182/blood-2002-02-0569
-
(2003)
Blood
, vol.101
, pp. 1155-1163
-
-
Sasmono, R.T.1
Oceandy, D.2
Pollard, J.W.3
Tong, W.4
Pavli, P.5
Wainwright, B.J.6
-
23
-
-
79953729333
-
Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunity
-
Hume DA. Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunity. J Leukoc Biol (2011) 89:525-38. doi:10.1189/jlb.0810472
-
(2011)
J Leukoc Biol
, vol.89
, pp. 525-538
-
-
Hume, D.A.1
-
24
-
-
35748937331
-
Construction, visualisation, and clustering of transcription networks from microarray expression data
-
Freeman TC, Goldovsky L, Brosch M, Van Dongen S, Maziere P, Grocock RJ, et al. Construction, visualisation, and clustering of transcription networks from microarray expression data. PLoS Comput Biol (2007) 3:2032-42. doi:10.1371/journal.pcbi.0030206
-
(2007)
PLoS Comput Biol
, vol.3
, pp. 2032-2042
-
-
Freeman, T.C.1
Goldovsky, L.2
Brosch, M.3
Van Dongen, S.4
Maziere, P.5
Grocock, R.J.6
-
25
-
-
73349116606
-
Network visualization and analysis of gene expression data using BioLayout express (3D)
-
Theocharidis A, Van Dongen S, Enright AJ, Freeman TC. Network visualization and analysis of gene expression data using BioLayout express (3D). Nat Protoc (2009) 4:1535-50. doi:10.1038/nprot.2009.177
-
(2009)
Nat Protoc
, vol.4
, pp. 1535-1550
-
-
Theocharidis, A.1
Van Dongen, S.2
Enright, A.J.3
Freeman, T.C.4
-
26
-
-
77952811111
-
Functional clustering and lineage markers: insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populations
-
Hume DA, Summers KM, Raza S, Baillie JK, Freeman TC. Functional clustering and lineage markers: insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populations. Genomics (2010) 95:328-38. doi:10.1016/j.ygeno.2010.03.002
-
(2010)
Genomics
, vol.95
, pp. 328-338
-
-
Hume, D.A.1
Summers, K.M.2
Raza, S.3
Baillie, J.K.4
Freeman, T.C.5
-
27
-
-
77955412944
-
Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations
-
Mabbott NA, Kenneth Baillie J, Hume DA, Freeman TC. Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations. Immunobiology (2010) 215:724-36. doi:10.1016/j.imbio.2010.05.012
-
(2010)
Immunobiology
, vol.215
, pp. 724-736
-
-
Mabbott, N.A.1
Kenneth Baillie, J.2
Hume, D.A.3
Freeman, T.C.4
-
28
-
-
84884297351
-
An expression atlas of human primary cells: inference of gene function from coexpression networks
-
Mabbott NA, Baillie JK, Brown H, Freeman TC, Hume DA. An expression atlas of human primary cells: inference of gene function from coexpression networks. BMC Genomics (2013) 14:632. doi:10.1186/1471-2164-14-632
-
(2013)
BMC Genomics
, vol.14
, pp. 632
-
-
Mabbott, N.A.1
Baillie, J.K.2
Brown, H.3
Freeman, T.C.4
Hume, D.A.5
-
29
-
-
84868693721
-
A gene expression atlas of the domestic pig
-
Freeman TC, Ivens A, Baillie JK, Beraldi D, Barnett MW, Dorward D, et al. A gene expression atlas of the domestic pig. BMC Biol (2012) 10:90. doi:10.1186/1741-7007-10-90
-
(2012)
BMC Biol
, vol.10
, pp. 90
-
-
Freeman, T.C.1
Ivens, A.2
Baillie, J.K.3
Beraldi, D.4
Barnett, M.W.5
Dorward, D.6
-
30
-
-
84941123546
-
GeneFriends: a human RNA-seq-based gene and transcript co-expression database
-
van Dam S, Craig T, De Magalhaes JP. GeneFriends: a human RNA-seq-based gene and transcript co-expression database. Nucleic Acids Res (2015) 43:D1124-32. doi:10.1093/nar/gku1042
-
(2015)
Nucleic Acids Res
, vol.43
, pp. D1124-D1132
-
-
van Dam, S.1
Craig, T.2
De Magalhaes, J.P.3
-
31
-
-
0033082496
-
TFEC is a macrophage-restricted member of the microphthalmia-TFE subfamily of basic helix-loop-helix leucine zipper transcription factors
-
Rehli M, Lichanska A, Cassady AI, Ostrowski MC, Hume DA. TFEC is a macrophage-restricted member of the microphthalmia-TFE subfamily of basic helix-loop-helix leucine zipper transcription factors. J Immunol (1999) 162:1559-65.
-
(1999)
J Immunol
, vol.162
, pp. 1559-1565
-
-
Rehli, M.1
Lichanska, A.2
Cassady, A.I.3
Ostrowski, M.C.4
Hume, D.A.5
-
32
-
-
0035965217
-
Genetic and physical interactions between microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiation
-
Luchin A, Suchting S, Merson T, Rosol TJ, Hume DA, Cassady AI, et al. Genetic and physical interactions between microphthalmia transcription factor and PU.1 are necessary for osteoclast gene expression and differentiation. J Biol Chem (2001) 276:36703-10. doi:10.1074/jbc.M106418200
-
(2001)
J Biol Chem
, vol.276
, pp. 36703-36710
-
-
Luchin, A.1
Suchting, S.2
Merson, T.3
Rosol, T.J.4
Hume, D.A.5
Cassady, A.I.6
-
33
-
-
58749083404
-
Macrophages as APC and the dendritic cell myth
-
Hume DA. Macrophages as APC and the dendritic cell myth. J Immunol (2008) 181:5829-35. doi:10.4049/jimmunol.181.9.5829
-
(2008)
J Immunol
, vol.181
, pp. 5829-5835
-
-
Hume, D.A.1
-
34
-
-
84874038349
-
Can DCs be distinguished from macrophages by molecular signatures?
-
Hume DA, Mabbott N, Raza S, Freeman TC. Can DCs be distinguished from macrophages by molecular signatures?. Nat Immunol (2013) 14:187-9. doi:10.1038/ni.2516
-
(2013)
Nat Immunol
, vol.14
, pp. 187-189
-
-
Hume, D.A.1
Mabbott, N.2
Raza, S.3
Freeman, T.C.4
-
35
-
-
84900461408
-
Development and function of dendritic cell subsets
-
Mildner A, Jung S. Development and function of dendritic cell subsets. Immunity (2014) 40:642-56. doi:10.1016/j.immuni.2014.04.016
-
(2014)
Immunity
, vol.40
, pp. 642-656
-
-
Mildner, A.1
Jung, S.2
-
36
-
-
77349124883
-
Origin and development of dendritic cells
-
Liu K, Nussenzweig MC. Origin and development of dendritic cells. Immunol Rev (2010) 234:45-54. doi:10.1111/j.0105-2896.2009.00879.x
-
(2010)
Immunol Rev
, vol.234
, pp. 45-54
-
-
Liu, K.1
Nussenzweig, M.C.2
-
37
-
-
84875528275
-
The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting
-
Merad M, Sathe P, Helft J, Miller J, Mortha A. The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. Annu Rev Immunol (2013) 31:563-604. doi:10.1146/annurev-immunol-020711-074950
-
(2013)
Annu Rev Immunol
, vol.31
, pp. 563-604
-
-
Merad, M.1
Sathe, P.2
Helft, J.3
Miller, J.4
Mortha, A.5
-
38
-
-
84865418665
-
Deciphering the transcriptional network of the dendritic cell lineage
-
Miller JC, Brown BD, Shay T, Gautier EL, Jojic V, Cohain A, et al. Deciphering the transcriptional network of the dendritic cell lineage. Nat Immunol (2012) 13:888-99. doi:10.1038/ni.2370
-
(2012)
Nat Immunol
, vol.13
, pp. 888-899
-
-
Miller, J.C.1
Brown, B.D.2
Shay, T.3
Gautier, E.L.4
Jojic, V.5
Cohain, A.6
-
39
-
-
84867740805
-
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
-
Gautier EL, Shay T, Miller J, Greter M, Jakubzick C, Ivanov S, et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat Immunol (2012) 13:1118-28. doi:10.1038/ni.2419
-
(2012)
Nat Immunol
, vol.13
, pp. 1118-1128
-
-
Gautier, E.L.1
Shay, T.2
Miller, J.3
Greter, M.4
Jakubzick, C.5
Ivanov, S.6
-
40
-
-
84897406127
-
A promoter-level mammalian expression atlas
-
Consortium (The FANTOM Consortium), Forrest AR, Kawaji H, Rehli M, Baillie JK, De Hoon MJ, et al. A promoter-level mammalian expression atlas. Nature (2014) 507:462-70. doi:10.1038/nature13182
-
(2014)
Nature
, vol.507
, pp. 462-470
-
-
Forrest, A.R.1
Kawaji, H.2
Rehli, M.3
Baillie, J.K.4
De Hoon, M.J.5
-
41
-
-
84929208111
-
Technical advance: transcription factor, promoter, and enhancer utilization in human myeloid cells
-
Joshi A, Pooley C, Freeman TC, Lennartsson A, Babina M, Schmidl C, et al. Technical advance: transcription factor, promoter, and enhancer utilization in human myeloid cells. J Leukoc Biol (2015) 97:985-95. doi:10.1189/jlb.6TA1014-477RR
-
(2015)
J Leukoc Biol
, vol.97
, pp. 985-995
-
-
Joshi, A.1
Pooley, C.2
Freeman, T.C.3
Lennartsson, A.4
Babina, M.5
Schmidl, C.6
-
42
-
-
0015619335
-
Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution
-
Steinman RM, Cohn ZA. Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J Exp Med (1973) 137:1142-62. doi:10.1084/jem.137.5.1142
-
(1973)
J Exp Med
, vol.137
, pp. 1142-1162
-
-
Steinman, R.M.1
Cohn, Z.A.2
-
43
-
-
84893745524
-
Identification of a unique TGF-beta-dependent molecular and functional signature in microglia
-
Butovsky O, Jedrychowski MP, Moore CS, Cialic R, Lanser AJ, Gabriely G, et al. Identification of a unique TGF-beta-dependent molecular and functional signature in microglia. Nat Neurosci (2014) 17:131-43. doi:10.1038/nn.3599
-
(2014)
Nat Neurosci
, vol.17
, pp. 131-143
-
-
Butovsky, O.1
Jedrychowski, M.P.2
Moore, C.S.3
Cialic, R.4
Lanser, A.J.5
Gabriely, G.6
-
44
-
-
0021564388
-
The cell biology of macrophage activation
-
Adams DO, Hamilton TA. The cell biology of macrophage activation. Annu Rev Immunol (1984) 2:283-318. doi:10.1146/annurev.iy.02.040184.001435
-
(1984)
Annu Rev Immunol
, vol.2
, pp. 283-318
-
-
Adams, D.O.1
Hamilton, T.A.2
-
45
-
-
0842266786
-
Interferon-gamma: an overview of signals, mechanisms and functions
-
Schroder K, Hertzog PJ, Ravasi T, Hume DA. Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol (2004) 75:163-89. doi:10.1189/jlb.0603252
-
(2004)
J Leukoc Biol
, vol.75
, pp. 163-189
-
-
Schroder, K.1
Hertzog, P.J.2
Ravasi, T.3
Hume, D.A.4
-
46
-
-
0037769059
-
Monocyte heterogeneity and innate immunity
-
Taylor PR, Gordon S. Monocyte heterogeneity and innate immunity. Immunity (2003) 19:2-4. doi:10.1016/S1074-7613(03)00178-X
-
(2003)
Immunity
, vol.19
, pp. 2-4
-
-
Taylor, P.R.1
Gordon, S.2
-
47
-
-
48349102876
-
Macrophage polarization in tumour progression
-
Sica A, Larghi P, Mancino A, Rubino L, Porta C, Totaro MG, et al. Macrophage polarization in tumour progression. Semin Cancer Biol (2008) 18:349-55. doi:10.1016/j.semcancer.2008.03.004
-
(2008)
Semin Cancer Biol
, vol.18
, pp. 349-355
-
-
Sica, A.1
Larghi, P.2
Mancino, A.3
Rubino, L.4
Porta, C.5
Totaro, M.G.6
-
48
-
-
77953268611
-
Alternative activation of macrophages: mechanism and functions
-
Gordon S, Martinez FO. Alternative activation of macrophages: mechanism and functions. Immunity (2010) 32:593-604. doi:10.1016/j.immuni.2010.05.007
-
(2010)
Immunity
, vol.32
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
49
-
-
84857883847
-
Macrophage plasticity and polarization: in vivo veritas
-
Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest (2012) 122:787-95. doi:10.1172/JCI59643
-
(2012)
J Clin Invest
, vol.122
, pp. 787-795
-
-
Sica, A.1
Mantovani, A.2
-
50
-
-
80355146399
-
Transcriptional regulation of macrophage polarization: enabling diversity with identity
-
Lawrence T, Natoli G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat Rev Immunol (2011) 11:750-61. doi:10.1038/nri3088
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 750-761
-
-
Lawrence, T.1
Natoli, G.2
-
52
-
-
84875658660
-
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences
-
Martinez FO, Helming L, Milde R, Varin A, Melgert BN, Draijer C, et al. Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences. Blood (2013) 121:e57-69. doi:10.1182/blood-2012-06-436212
-
(2013)
Blood
, vol.121
, pp. e57-e69
-
-
Martinez, F.O.1
Helming, L.2
Milde, R.3
Varin, A.4
Melgert, B.N.5
Draijer, C.6
-
53
-
-
84904394690
-
Macrophage activation and polarization: nomenclature and experimental guidelines
-
Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity (2014) 41:14-20. doi:10.1016/j.immuni.2014.06.008
-
(2014)
Immunity
, vol.41
, pp. 14-20
-
-
Murray, P.J.1
Allen, J.E.2
Biswas, S.K.3
Fisher, E.A.4
Gilroy, D.W.5
Goerdt, S.6
-
54
-
-
33646547951
-
Systems biology approaches identify ATF3 as a negative regulator of toll-like receptor 4
-
Gilchrist M, Thorsson V, Li B, Rust AG, Korb M, Roach JC, et al. Systems biology approaches identify ATF3 as a negative regulator of toll-like receptor 4. Nature (2006) 441:173-8. doi:10.1038/nature04768
-
(2006)
Nature
, vol.441
, pp. 173-178
-
-
Gilchrist, M.1
Thorsson, V.2
Li, B.3
Rust, A.G.4
Korb, M.5
Roach, J.C.6
-
55
-
-
33646484899
-
Transcriptional network dynamics in macrophage activation
-
Nilsson R, Bajic VB, Suzuki H, Di Bernardo D, Bjorkegren J, Katayama S, et al. Transcriptional network dynamics in macrophage activation. Genomics (2006) 88:133-42. doi:10.1016/j.ygeno.2006.03.022
-
(2006)
Genomics
, vol.88
, pp. 133-142
-
-
Nilsson, R.1
Bajic, V.B.2
Suzuki, H.3
Di Bernardo, D.4
Bjorkegren, J.5
Katayama, S.6
-
56
-
-
77949977555
-
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
-
Ghisletti S, Barozzi I, Mietton F, Polletti S, De Santa F, Venturini E, et al. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity (2010) 32:317-28. doi:10.1016/j.immuni.2010.02.008
-
(2010)
Immunity
, vol.32
, pp. 317-328
-
-
Ghisletti, S.1
Barozzi, I.2
Mietton, F.3
Polletti, S.4
De Santa, F.5
Venturini, E.6
-
57
-
-
84864251757
-
Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions
-
Bhatt DM, Pandya-Jones A, Tong AJ, Barozzi I, Lissner MM, Natoli G, et al. Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions. Cell (2012) 150:279-90. doi:10.1016/j.cell.2012.05.043
-
(2012)
Cell
, vol.150
, pp. 279-290
-
-
Bhatt, D.M.1
Pandya-Jones, A.2
Tong, A.J.3
Barozzi, I.4
Lissner, M.M.5
Natoli, G.6
-
58
-
-
84888641656
-
Effect of natural genetic variation on enhancer selection and function
-
Heinz S, Romanoski CE, Benner C, Allison KA, Kaikkonen MU, Orozco LD, et al. Effect of natural genetic variation on enhancer selection and function. Nature (2013) 503:487-92. doi:10.1038/nature12615
-
(2013)
Nature
, vol.503
, pp. 487-492
-
-
Heinz, S.1
Romanoski, C.E.2
Benner, C.3
Allison, K.A.4
Kaikkonen, M.U.5
Orozco, L.D.6
-
59
-
-
84872522528
-
Latent enhancers activated by stimulation in differentiated cells
-
Ostuni R, Piccolo V, Barozzi I, Polletti S, Termanini A, Bonifacio S, et al. Latent enhancers activated by stimulation in differentiated cells. Cell (2013) 152:157-71. doi:10.1016/j.cell.2012.12.018
-
(2013)
Cell
, vol.152
, pp. 157-171
-
-
Ostuni, R.1
Piccolo, V.2
Barozzi, I.3
Polletti, S.4
Termanini, A.5
Bonifacio, S.6
-
60
-
-
22144464423
-
Inflammation suppressor genes: please switch out all the lights
-
Wells CA, Ravasi T, Hume DA. Inflammation suppressor genes: please switch out all the lights. J Leukoc Biol (2005) 78:9-13. doi:10.1189/jlb.1204710
-
(2005)
J Leukoc Biol
, vol.78
, pp. 9-13
-
-
Wells, C.A.1
Ravasi, T.2
Hume, D.A.3
-
61
-
-
84904993091
-
Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators
-
Raza S, Barnett MW, Barnett-Itzhaki Z, Amit I, Hume DA, Freeman TC. Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators. J Leukoc Biol (2014) 96(2):167-83. doi:10.1189/jlb.6HI0313-169R
-
(2014)
J Leukoc Biol
, vol.96
, Issue.2
, pp. 167-183
-
-
Raza, S.1
Barnett, M.W.2
Barnett-Itzhaki, Z.3
Amit, I.4
Hume, D.A.5
Freeman, T.C.6
-
62
-
-
0642367583
-
Genetic control of the innate immune response
-
Wells CA, Ravasi T, Faulkner GJ, Carninci P, Okazaki Y, Hayashizaki Y, et al. Genetic control of the innate immune response. BMC Immunol (2003) 4:5. doi:10.1186/1471-2172-4-5
-
(2003)
BMC Immunol
, vol.4
, pp. 5
-
-
Wells, C.A.1
Ravasi, T.2
Faulkner, G.J.3
Carninci, P.4
Okazaki, Y.5
Hayashizaki, Y.6
-
63
-
-
70350716441
-
Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences
-
Schilling E, El Chartouni C, Rehli M. Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences. Genome Res (2009) 19:2028-35. doi:10.1101/gr.095562.109
-
(2009)
Genome Res
, vol.19
, pp. 2028-2035
-
-
Schilling, E.1
El Chartouni, C.2
Rehli, M.3
-
64
-
-
36849064857
-
Natural cathepsin E deficiency in the immune system of C57BL/6J mice
-
Tulone C, Tsang J, Prokopowicz Z, Grosvenor N, Chain B. Natural cathepsin E deficiency in the immune system of C57BL/6J mice. Immunogenetics (2007) 59:927-35. doi:10.1007/s00251-007-0256-0
-
(2007)
Immunogenetics
, vol.59
, pp. 927-935
-
-
Tulone, C.1
Tsang, J.2
Prokopowicz, Z.3
Grosvenor, N.4
Chain, B.5
-
65
-
-
82555186955
-
Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
-
Nguyen KD, Qiu Y, Cui X, Goh YP, Mwangi J, David T, et al. Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis. Nature (2011) 480:104-8. doi:10.1038/nature10653
-
(2011)
Nature
, vol.480
, pp. 104-108
-
-
Nguyen, K.D.1
Qiu, Y.2
Cui, X.3
Goh, Y.P.4
Mwangi, J.5
David, T.6
-
66
-
-
21044457085
-
Transcription factor Tfec contributes to the IL-4-inducible expression of a small group of genes in mouse macrophages including the granulocyte colony-stimulating factor receptor
-
Rehli M, Sulzbacher S, Pape S, Ravasi T, Wells CA, Heinz S, et al. Transcription factor Tfec contributes to the IL-4-inducible expression of a small group of genes in mouse macrophages including the granulocyte colony-stimulating factor receptor. J Immunol (2005) 174:7111-22. doi:10.4049/jimmunol.174.11.7111
-
(2005)
J Immunol
, vol.174
, pp. 7111-7122
-
-
Rehli, M.1
Sulzbacher, S.2
Pape, S.3
Ravasi, T.4
Wells, C.A.5
Heinz, S.6
-
67
-
-
84859993180
-
Conservation and divergence in toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages
-
Schroder K, Irvine KM, Taylor MS, Bokil NJ, Le Cao KA, Masterman KA, et al. Conservation and divergence in toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages. Proc Natl Acad Sci U S A (2012) 109:E944-53. doi:10.1073/pnas.1110156109
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. E944-E953
-
-
Schroder, K.1
Irvine, K.M.2
Taylor, M.S.3
Bokil, N.J.4
Le Cao, K.A.5
Masterman, K.A.6
-
68
-
-
79957869585
-
The mononuclear phagocyte system of the pig as a model for understanding human innate immunity and disease
-
Fairbairn L, Kapetanovic R, Sester DP, Hume DA. The mononuclear phagocyte system of the pig as a model for understanding human innate immunity and disease. J Leukoc Biol (2011) 89:855-71. doi:10.1189/jlb.1110607
-
(2011)
J Leukoc Biol
, vol.89
, pp. 855-871
-
-
Fairbairn, L.1
Kapetanovic, R.2
Sester, D.P.3
Hume, D.A.4
-
69
-
-
84859404700
-
Pig bone marrow-derived macrophages resemble human macrophages in their response to bacterial lipopolysaccharide
-
Kapetanovic R, Fairbairn L, Beraldi D, Sester DP, Archibald AL, Tuggle CK, et al. Pig bone marrow-derived macrophages resemble human macrophages in their response to bacterial lipopolysaccharide. J Immunol (2012) 188:3382-94. doi:10.4049/jimmunol.1102649
-
(2012)
J Immunol
, vol.188
, pp. 3382-3394
-
-
Kapetanovic, R.1
Fairbairn, L.2
Beraldi, D.3
Sester, D.P.4
Archibald, A.L.5
Tuggle, C.K.6
-
70
-
-
84928705290
-
A transcriptional perspective on human macrophage biology
-
Schultze JL, Freeman T, Hume DA, Latz E. A transcriptional perspective on human macrophage biology. Semin Immunol (2015) 27:44-50. doi:10.1016/j.smim.2015.02.001
-
(2015)
Semin Immunol
, vol.27
, pp. 44-50
-
-
Schultze, J.L.1
Freeman, T.2
Hume, D.A.3
Latz, E.4
-
71
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol (2008) 8:958-69. doi:10.1038/nri2448
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
72
-
-
84894102230
-
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
-
Xue J, Schmidt SV, Sander J, Draffehn A, Krebs W, Quester I, et al. Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity (2014) 40:274-88. doi:10.1016/j.immuni.2014.01.006
-
(2014)
Immunity
, vol.40
, pp. 274-288
-
-
Xue, J.1
Schmidt, S.V.2
Sander, J.3
Draffehn, A.4
Krebs, W.5
Quester, I.6
-
73
-
-
63149088164
-
Trophic macrophages in development and disease
-
Pollard JW. Trophic macrophages in development and disease. Nat Rev Immunol (2009) 9:259-70. doi:10.1038/nri2528
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 259-270
-
-
Pollard, J.W.1
-
74
-
-
84880014085
-
Coexpression analysis of large cancer datasets provides insight into the cellular phenotypes of the tumour microenvironment
-
Doig TN, Hume DA, Theocharidis T, Goodlad JR, Gregory CD, Freeman TC. Coexpression analysis of large cancer datasets provides insight into the cellular phenotypes of the tumour microenvironment. BMC Genomics (2013) 14:469. doi:10.1186/1471-2164-14-469
-
(2013)
BMC Genomics
, vol.14
, pp. 469
-
-
Doig, T.N.1
Hume, D.A.2
Theocharidis, T.3
Goodlad, J.R.4
Gregory, C.D.5
Freeman, T.C.6
-
75
-
-
84883087751
-
The impact of breed and tissue compartment on the response of pig macrophages to lipopolysaccharide
-
Kapetanovic R, Fairbairn L, Downing A, Beraldi D, Sester DP, Freeman TC, et al. The impact of breed and tissue compartment on the response of pig macrophages to lipopolysaccharide. BMC Genomics (2013) 14:581. doi:10.1186/1471-2164-14-581
-
(2013)
BMC Genomics
, vol.14
, pp. 581
-
-
Kapetanovic, R.1
Fairbairn, L.2
Downing, A.3
Beraldi, D.4
Sester, D.P.5
Freeman, T.C.6
-
76
-
-
84896742056
-
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression
-
Fairfax BP, Humburg P, Makino S, Naranbhai V, Wong D, Lau E, et al. Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression. Science (2014) 343:1246949. doi:10.1126/science.1246949
-
(2014)
Science
, vol.343
-
-
Fairfax, B.P.1
Humburg, P.2
Makino, S.3
Naranbhai, V.4
Wong, D.5
Lau, E.6
-
77
-
-
84911126794
-
Transcriptomic analysis of mononuclear phagocyte differentiation and activation
-
Hume DA, Freeman TC. Transcriptomic analysis of mononuclear phagocyte differentiation and activation. Immunol Rev (2014) 262:74-84. doi:10.1111/imr.12211
-
(2014)
Immunol Rev
, vol.262
, pp. 74-84
-
-
Hume, D.A.1
Freeman, T.C.2
-
78
-
-
84862777209
-
IFITM3 restricts the morbidity and mortality associated with influenza
-
Everitt AR, Clare S, Pertel T, John SP, Wash RS, Smith SE, et al. IFITM3 restricts the morbidity and mortality associated with influenza. Nature (2012) 484:519-23. doi:10.1038/nature10921
-
(2012)
Nature
, vol.484
, pp. 519-523
-
-
Everitt, A.R.1
Clare, S.2
Pertel, T.3
John, S.P.4
Wash, R.S.5
Smith, S.E.6
-
79
-
-
33847408050
-
Gene expression patterns in blood leukocytes discriminate patients with acute infections
-
Ramilo O, Allman W, Chung W, Mejias A, Ardura M, Glaser C, et al. Gene expression patterns in blood leukocytes discriminate patients with acute infections. Blood (2007) 109:2066-77. doi:10.1182/blood-2006-02-002477
-
(2007)
Blood
, vol.109
, pp. 2066-2077
-
-
Ramilo, O.1
Allman, W.2
Chung, W.3
Mejias, A.4
Ardura, M.5
Glaser, C.6
-
80
-
-
84886057701
-
Interferons in Sjogren's syndrome: genes, mechanisms, and effects
-
Li H, Ice JA, Lessard CJ, Sivils KL. Interferons in Sjogren's syndrome: genes, mechanisms, and effects. Front Immunol (2013) 4:290. doi:10.3389/fimmu.2013.00290
-
(2013)
Front Immunol
, vol.4
, pp. 290
-
-
Li, H.1
Ice, J.A.2
Lessard, C.J.3
Sivils, K.L.4
-
81
-
-
84873404949
-
The interferon signature in autoimmune diseases
-
Ronnblom L, Eloranta ML. The interferon signature in autoimmune diseases. Curr Opin Rheumatol (2013) 25:248-53. doi:10.1097/BOR.0b013e32835c7e32
-
(2013)
Curr Opin Rheumatol
, vol.25
, pp. 248-253
-
-
Ronnblom, L.1
Eloranta, M.L.2
-
82
-
-
84901641596
-
Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures
-
Chiche L, Jourde-Chiche N, Whalen E, Presnell S, Gersuk V, Dang K, et al. Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures. Arthritis Rheumatol (2014) 66(6):1583-95. doi:10.1002/art.38628
-
(2014)
Arthritis Rheumatol
, vol.66
, Issue.6
, pp. 1583-1595
-
-
Chiche, L.1
Jourde-Chiche, N.2
Whalen, E.3
Presnell, S.4
Gersuk, V.5
Dang, K.6
-
83
-
-
67649648237
-
Control of inducible gene expression by signal-dependent transcriptional elongation
-
Hargreaves DC, Horng T, Medzhitov R. Control of inducible gene expression by signal-dependent transcriptional elongation. Cell (2009) 138:129-45. doi:10.1016/j.cell.2009.05.047
-
(2009)
Cell
, vol.138
, pp. 129-145
-
-
Hargreaves, D.C.1
Horng, T.2
Medzhitov, R.3
-
84
-
-
70349443224
-
Transcriptional control of the inflammatory response
-
Medzhitov R, Horng T. Transcriptional control of the inflammatory response. Nat Rev Immunol (2009) 9:692-703. doi:10.1038/nri2634
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 692-703
-
-
Medzhitov, R.1
Horng, T.2
-
85
-
-
0027972426
-
Comparison of the expression and function of the transcription factor PU.1 (Spi-1 proto-oncogene) between murine macrophages and B lymphocytes
-
Ross IL, Dunn TL, Yue X, Roy S, Barnett CJ, Hume DA. Comparison of the expression and function of the transcription factor PU.1 (Spi-1 proto-oncogene) between murine macrophages and B lymphocytes. Oncogene (1994) 9:121-32.
-
(1994)
Oncogene
, vol.9
, pp. 121-132
-
-
Ross, I.L.1
Dunn, T.L.2
Yue, X.3
Roy, S.4
Barnett, C.J.5
Hume, D.A.6
-
86
-
-
84881236410
-
Positive feedback between PU.1 and the cell cycle controls myeloid differentiation
-
Kueh HY, Champhekar A, Nutt SL, Elowitz MB, Rothenberg EV. Positive feedback between PU.1 and the cell cycle controls myeloid differentiation. Science (2013) 341:670-3. doi:10.1126/science.1240831
-
(2013)
Science
, vol.341
, pp. 670-673
-
-
Kueh, H.Y.1
Champhekar, A.2
Nutt, S.L.3
Elowitz, M.B.4
Rothenberg, E.V.5
-
87
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell (2010) 38:576-89. doi:10.1016/j.molcel.2010.05.004
-
(2010)
Mol Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
Benner, C.2
Spann, N.3
Bertolino, E.4
Lin, Y.C.5
Laslo, P.6
-
88
-
-
84857710083
-
Roles of lineage-determining transcription factors in establishing open chromatin: lessons from high-throughput studies
-
Heinz S, Glass CK. Roles of lineage-determining transcription factors in establishing open chromatin: lessons from high-throughput studies. Curr Top Microbiol Immunol (2012) 356:1-15. doi:10.1007/82_2011_142
-
(2012)
Curr Top Microbiol Immunol
, vol.356
, pp. 1-15
-
-
Heinz, S.1
Glass, C.K.2
-
89
-
-
84901921616
-
Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers
-
Barozzi I, Simonatto M, Bonifacio S, Yang L, Rohs R, Ghisletti S, et al. Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers. Mol Cell (2014) 54:844-57. doi:10.1016/j.molcel.2014.04.006
-
(2014)
Mol Cell
, vol.54
, pp. 844-857
-
-
Barozzi, I.1
Simonatto, M.2
Bonifacio, S.3
Yang, L.4
Rohs, R.5
Ghisletti, S.6
-
90
-
-
84911101566
-
Epigenomics of macrophages
-
Gosselin D, Glass CK. Epigenomics of macrophages. Immunol Rev (2014) 262:96-112. doi:10.1111/imr.12213
-
(2014)
Immunol Rev
, vol.262
, pp. 96-112
-
-
Gosselin, D.1
Glass, C.K.2
-
91
-
-
84922998982
-
A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages
-
Mancino A, Termanini A, Barozzi I, Ghisletti S, Ostuni R, Prosperini E, et al. A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages. Genes Dev (2015) 29:394-408. doi:10.1101/gad.257592.114
-
(2015)
Genes Dev
, vol.29
, pp. 394-408
-
-
Mancino, A.1
Termanini, A.2
Barozzi, I.3
Ghisletti, S.4
Ostuni, R.5
Prosperini, E.6
-
92
-
-
24644519490
-
The transcriptional landscape of the mammalian genome
-
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, et al. The transcriptional landscape of the mammalian genome. Science (2005) 309:1559-63. doi:10.1126/science.1112014
-
(2005)
Science
, vol.309
, pp. 1559-1563
-
-
Carninci, P.1
Kasukawa, T.2
Katayama, S.3
Gough, J.4
Frith, M.C.5
Maeda, N.6
-
93
-
-
33744805985
-
Genome-wide analysis of mammalian promoter architecture and evolution
-
Carninci P, Sandelin A, Lenhard B, Katayama S, Shimokawa K, Ponjavic J, et al. Genome-wide analysis of mammalian promoter architecture and evolution. Nat Genet (2006) 38:626-35. doi:10.1038/ng1789
-
(2006)
Nat Genet
, vol.38
, pp. 626-635
-
-
Carninci, P.1
Sandelin, A.2
Lenhard, B.3
Katayama, S.4
Shimokawa, K.5
Ponjavic, J.6
-
94
-
-
68849123047
-
Methods for analyzing deep sequencing expression data: constructing the human and mouse promoterome with deepCAGE data
-
Balwierz PJ, Carninci P, Daub CO, Kawai J, Hayashizaki Y, Van Belle W, et al. Methods for analyzing deep sequencing expression data: constructing the human and mouse promoterome with deepCAGE data. Genome Biol (2009) 10:R79. doi:10.1186/gb-2009-10-7-r79
-
(2009)
Genome Biol
, vol.10
, pp. R79
-
-
Balwierz, P.J.1
Carninci, P.2
Daub, C.O.3
Kawai, J.4
Hayashizaki, Y.5
Van Belle, W.6
-
95
-
-
20644450804
-
Negative regulation of toll-like receptor-mediated immune responses
-
Liew FY, Xu D, Brint EK, O'Neill LA. Negative regulation of toll-like receptor-mediated immune responses. Nat Rev Immunol (2005) 5:446-58. doi:10.1038/nri1630
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 446-458
-
-
Liew, F.Y.1
Xu, D.2
Brint, E.K.3
O'Neill, L.A.4
-
96
-
-
33745023799
-
Alternate transcription of the toll-like receptor signaling cascade
-
Wells CA, Chalk AM, Forrest A, Taylor D, Waddell N, Schroder K, et al. Alternate transcription of the toll-like receptor signaling cascade. Genome Biol (2006) 7:R10. doi:10.1186/gb-2006-7-2-r10
-
(2006)
Genome Biol
, vol.7
, pp. R10
-
-
Wells, C.A.1
Chalk, A.M.2
Forrest, A.3
Taylor, D.4
Waddell, N.5
Schroder, K.6
-
97
-
-
84881526410
-
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription
-
Kaikkonen MU, Spann NJ, Heinz S, Romanoski CE, Allison KA, Stender JD, et al. Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription. Mol Cell (2013) 51:310-25. doi:10.1016/j.molcel.2013.07.010
-
(2013)
Mol Cell
, vol.51
, pp. 310-325
-
-
Kaikkonen, M.U.1
Spann, N.J.2
Heinz, S.3
Romanoski, C.E.4
Allison, K.A.5
Stender, J.D.6
-
98
-
-
84897446230
-
Enhancer RNAs and regulated transcriptional programs
-
Lam MT, Li W, Rosenfeld MG, Glass CK. Enhancer RNAs and regulated transcriptional programs. Trends Biochem Sci (2014) 39:170-82. doi:10.1016/j.tibs.2014.02.007
-
(2014)
Trends Biochem Sci
, vol.39
, pp. 170-182
-
-
Lam, M.T.1
Li, W.2
Rosenfeld, M.G.3
Glass, C.K.4
-
99
-
-
84897459814
-
An atlas of active enhancers across human cell types and tissues
-
Andersson R, Gebhard C, Miguel-Escalada I, Hoof I, Bornholdt J, Boyd M, et al. An atlas of active enhancers across human cell types and tissues. Nature (2014) 507:455-61. doi:10.1038/nature12787
-
(2014)
Nature
, vol.507
, pp. 455-461
-
-
Andersson, R.1
Gebhard, C.2
Miguel-Escalada, I.3
Hoof, I.4
Bornholdt, J.5
Boyd, M.6
-
100
-
-
84923796255
-
Gene regulation. Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
-
Arner E, Daub CO, Vitting-Seerup K, Andersson R, Lilje B, Drablos F, et al. Gene regulation. Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science (2015) 347:1010-4. doi:10.1126/science.1259418
-
(2015)
Science
, vol.347
, pp. 1010-1014
-
-
Arner, E.1
Daub, C.O.2
Vitting-Seerup, K.3
Andersson, R.4
Lilje, B.5
Drablos, F.6
-
101
-
-
0023407453
-
The human alpha 1-antitrypsin gene is transcribed from two different promoters in macrophages and hepatocytes
-
Perlino E, Cortese R, Ciliberto G. The human alpha 1-antitrypsin gene is transcribed from two different promoters in macrophages and hepatocytes. EMBO J (1987) 6:2767-71.
-
(1987)
EMBO J
, vol.6
, pp. 2767-2771
-
-
Perlino, E.1
Cortese, R.2
Ciliberto, G.3
-
102
-
-
84878997106
-
Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells
-
Shalek AK, Satija R, Adiconis X, Gertner RS, Gaublomme JT, Raychowdhury R, et al. Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells. Nature (2013) 498:236-40. doi:10.1038/nature12172
-
(2013)
Nature
, vol.498
, pp. 236-240
-
-
Shalek, A.K.1
Satija, R.2
Adiconis, X.3
Gertner, R.S.4
Gaublomme, J.T.5
Raychowdhury, R.6
-
103
-
-
0036134881
-
Generation of diversity in the innate immune system: macrophage heterogeneity arises from gene-autonomous transcriptional probability of individual inducible genes
-
Ravasi T, Wells C, Forest A, Underhill DM, Wainwright BJ, Aderem A, et al. Generation of diversity in the innate immune system: macrophage heterogeneity arises from gene-autonomous transcriptional probability of individual inducible genes. J Immunol (2002) 168:44-50. doi:10.4049/jimmunol.168.1.44
-
(2002)
J Immunol
, vol.168
, pp. 44-50
-
-
Ravasi, T.1
Wells, C.2
Forest, A.3
Underhill, D.M.4
Wainwright, B.J.5
Aderem, A.6
-
104
-
-
0038731119
-
Monoallelic expression of the murine gene encoding toll-like receptor 4
-
Pereira JP, Girard R, Chaby R, Cumano A, Vieira P. Monoallelic expression of the murine gene encoding toll-like receptor 4. Nat Immunol (2003) 4:464-70. doi:10.1038/ni917
-
(2003)
Nat Immunol
, vol.4
, pp. 464-470
-
-
Pereira, J.P.1
Girard, R.2
Chaby, R.3
Cumano, A.4
Vieira, P.5
-
105
-
-
78349305550
-
High-throughput, single-cell NF-kappaB dynamics
-
Lee TK, Covert MW. High-throughput, single-cell NF-kappaB dynamics. Curr Opin Genet Dev (2010) 20:677-83. doi:10.1016/j.gde.2010.08.005
-
(2010)
Curr Opin Genet Dev
, vol.20
, pp. 677-683
-
-
Lee, T.K.1
Covert, M.W.2
-
106
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: update on toll-like receptors
-
Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on toll-like receptors. Nat Immunol (2010) 11:373-84. doi:10.1038/ni.1863
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
107
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi O, Akira S. Pattern recognition receptors and inflammation. Cell (2010) 140:805-20. doi:10.1016/j.cell.2010.01.022
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
108
-
-
0034307684
-
Probability in transcriptional regulation and its implications for leukocyte differentiation and inducible gene expression
-
Hume DA. Probability in transcriptional regulation and its implications for leukocyte differentiation and inducible gene expression. Blood (2000) 96:2323-8.
-
(2000)
Blood
, vol.96
, pp. 2323-2328
-
-
Hume, D.A.1
-
109
-
-
70349882120
-
Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses
-
Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, et al. Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. Science (2009) 326:257-63. doi:10.1126/science.1179050
-
(2009)
Science
, vol.326
, pp. 257-263
-
-
Amit, I.1
Garber, M.2
Chevrier, N.3
Leite, A.P.4
Donner, Y.5
Eisenhaure, T.6
-
110
-
-
65149083962
-
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line
-
Suzuki H, Forrest AR, Van Nimwegen E, Daub CO, Balwierz PJ, Irvine KM, et al. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet (2009) 41:553-62. doi:10.1038/ng.375
-
(2009)
Nat Genet
, vol.41
, pp. 553-562
-
-
Suzuki, H.1
Forrest, A.R.2
Van Nimwegen, E.3
Daub, C.O.4
Balwierz, P.J.5
Irvine, K.M.6
-
111
-
-
0028114205
-
Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes
-
Reddy MA, Yang BS, Yue X, Barnett CJ, Ross IL, Sweet MJ, et al. Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes. J Exp Med (1994) 180:2309-19. doi:10.1084/jem.180.6.2309
-
(1994)
J Exp Med
, vol.180
, pp. 2309-2319
-
-
Reddy, M.A.1
Yang, B.S.2
Yue, X.3
Barnett, C.J.4
Ross, I.L.5
Sweet, M.J.6
-
112
-
-
80053239657
-
Macrophages.com: an on-line community resource for innate immunity research
-
Robert C, Lu X, Law A, Freeman TC, Hume DA. Macrophages.com: an on-line community resource for innate immunity research. Immunobiology (2011) 216:1203-11. doi:10.1016/j.imbio.2011.07.025
-
(2011)
Immunobiology
, vol.216
, pp. 1203-1211
-
-
Robert, C.1
Lu, X.2
Law, A.3
Freeman, T.C.4
Hume, D.A.5
|