A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages

Genes and Development

Volumn 29, Issue 4, 2015, Pages 394-408

  Mancino, Alessandra ^a,b   Termanini, Alberto ^a,b   Barozzi, Iros ^a   Ghisletti, Serena ^a   Ostuni, Renato ^a   Prosperini, Elena ^a   Ozato, Keiko ^b   Natoli, Gioacchino ^a  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Chromatin; Epigenome; Inflammation; Interferon; IRF8; Macrophages; Transcription

Indexed keywords

BETA INTERFERON; GAMMA INTERFERON; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 12; INTERLEUKIN 23; LIPOPOLYSACCHARIDE; PURINERGIC RECEPTOR; STAT1 PROTEIN; STAT2 PROTEIN; TRANSCRIPTION FACTOR AP 1; INTERFERON REGULATORY FACTOR; PROTEIN BINDING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BINDING SITE; CONSENSUS SEQUENCE; CONTROLLED STUDY; DNA BINDING; ESSENTIAL GENE; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; GENE MUTATION; GENOME ANALYSIS; HISTONE ACETYLATION; MACROPHAGE; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RNA SEQUENCE; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANIMALS; CELLS, CULTURED; GENE EXPRESSION REGULATION; INTERFERON REGULATORY FACTORS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; PROTEIN BINDING;

EID: 84922998982     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.257592.114     Document Type: Article

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