-
1
-
-
0028559399
-
Enzymic studies on the animal and intestinal bacterial metabolism of geniposide
-
Akao, T., Kobashi, K., and Aburasa, M. (1994). Enzymic studies on the animal and intestinal bacterial metabolism of geniposide. Biol. Pharm. Bull. 17, 1573-1576.
-
(1994)
Biol. Pharm. Bull.
, vol.17
, pp. 1573-1576
-
-
Akao, T.1
Kobashi, K.2
Aburasa, M.3
-
2
-
-
79251623365
-
Diabetes and Alzheimers disease: Shared pathology and treatment?
-
Akter, K., Lanza, E.A., Martin, S.A., Myronyuk, N., Rua, M., and Raffa, R.B. (2011). Diabetes and Alzheimers disease: shared pathology and treatment? Br. J. Clin. Pharmacol. 71, 365-376.
-
(2011)
Br. J. Clin. Pharmacol.
, vol.71
, pp. 365-376
-
-
Akter, K.1
Lanza, E.A.2
Martin, S.A.3
Myronyuk, N.4
Rua, M.5
Raffa, R.B.6
-
3
-
-
84870056899
-
Nerve growth factor: From the early discoveries to the potential clinical use
-
Aloe, L., Rocco, M.L., Branching, P., and Mani, L. (2012). Nerve growth factor: from the early discoveries to the potential clinical use. J. Transl. Med. 10, 239.
-
(2012)
J. Transl. Med.
, vol.10
, pp. 239
-
-
Aloe, L.1
Rocco, M.L.2
Branching, P.3
Mani, L.4
-
4
-
-
74549169836
-
ER stress in Alzheimers disease: A novel neuronal trigger for inflammation and Alzheimers pathology
-
Antero, S., Anu, K., Tiina, S., Kai, K., and Johanna, O. (2009). ER stress in Alzheimers disease: a novel neuronal trigger for inflammation and Alzheimers pathology. J. Neuroinflamm. 6, 41.
-
(2009)
J. Neuroinflamm.
, vol.6
, pp. 41
-
-
Antero, S.1
Anu, K.2
Tiina, S.3
Kai, K.4
Johanna, O.5
-
5
-
-
1642289188
-
Role of τ protein in both physiological and pathological conditions
-
Avila, J., Lucas, J.J., Perez, M., and Hernandez, F. (2004). Role of τ protein in both physiological and pathological conditions. Physiol. Rev. 84, 361-384.
-
(2004)
Physiol. Rev.
, vol.84
, pp. 361-384
-
-
Avila, J.1
Lucas, J.J.2
Perez, M.3
Hernandez, F.4
-
6
-
-
51849162371
-
Redox-based endoplasmic reticulum dysfunction in neurological diseases
-
Banhegyi, G., Mandl, J., and Csala, M. (2008). Redox-based endoplasmic reticulum dysfunction in neurological diseases. J. Neurochem. 107, 20-34.
-
(2008)
J. Neurochem.
, vol.107
, pp. 20-34
-
-
Banhegyi, G.1
Mandl, J.2
Csala, M.3
-
7
-
-
33644553117
-
Increased cortical atrophy in patients with Alzheimers disease and type 2 diabetes mellitus
-
Biessels, G.J., De Leeuw, F.E., Lindeboom, J., Barkhof, F., and Scheltens, P. (2006). Increased cortical atrophy in patients with Alzheimers disease and type 2 diabetes mellitus. J. Neurol. Neurosurg. Psychiatr. 77, 304-307.
-
(2006)
J. Neurol. Neurosurg. Psychiatr.
, vol.77
, pp. 304-307
-
-
Biessels, G.J.1
De Leeuw, F.E.2
Lindeboom, J.3
Barkhof, F.4
Scheltens, P.5
-
8
-
-
63249107784
-
β-Arrestin 1 is required for PAC1 receptor-mediated potentiation of long-lasting ERK1/2 activation by glucose in pancreatic β-cells
-
Broca, C., Quoyer, J., Costes, S., Linck, N., Varrault, A., Deffayet, P.M., Bockaert, J., Dalle, S., and Bertrand, G. (2009). β-Arrestin 1 is required for PAC1 receptor-mediated potentiation of long-lasting ERK1/2 activation by glucose in pancreatic β-cells. J. Biol. Chem. 284, 4332-4342.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 4332-4342
-
-
Broca, C.1
Quoyer, J.2
Costes, S.3
Linck, N.4
Varrault, A.5
Deffayet, P.M.6
Bockaert, J.7
Dalle, S.8
Bertrand, G.9
-
9
-
-
84856146491
-
Acute activation of central GLP-1 receptors enhances hepatic insulin action and insulin secretion in high-fat-fed, insulin resistant mice
-
Burmeister, M.A., Ferre, T., Ayala, J.E., King, E.M., Holt, R.M., and Ayala, J.E. (2012). Acute activation of central GLP-1 receptors enhances hepatic insulin action and insulin secretion in high-fat-fed, insulin resistant mice. Am. J. Physiol. Endocrinol. Metab. 302, E334-E343.
-
(2012)
Am. J. Physiol. Endocrinol. Metab.
, vol.302
, pp. E334-E343
-
-
Burmeister, M.A.1
Ferre, T.2
Ayala, J.E.3
King, E.M.4
Holt, R.M.5
Ayala, J.E.6
-
10
-
-
84878796119
-
Nerve growth factor and Alzheimers disease: New facts for an old hypothesis
-
Cattaneo, A. and Calissano, P. (2012). Nerve growth factor and Alzheimers disease: new facts for an old hypothesis. Mol. Neurobiol. 46, 588-604.
-
(2012)
Mol. Neurobiol.
, vol.46
, pp. 588-604
-
-
Cattaneo, A.1
Calissano, P.2
-
11
-
-
48349136398
-
Simultaneous determination of geniposide and its metabolites genipin and genipinine in culture of Aspergillus Niger by HPLC
-
Chen, C., Han, F., Zhang, Y., Lu, J., and Shi, Y. (2008). Simultaneous determination of geniposide and its metabolites genipin and genipinine in culture of Aspergillus Niger by HPLC. Biomed. Chromatogr. 22, 753-757.
-
(2008)
Biomed. Chromatogr.
, vol.22
, pp. 753-757
-
-
Chen, C.1
Han, F.2
Zhang, Y.3
Lu, J.4
Shi, Y.5
-
12
-
-
65849437126
-
Iridoid glycosides from Gardeniae fructus for treatment of ankle sprain
-
Chen, Q.C., Zhang, W.Y., Youn, U., Kim, H., Lee, I., Jung, H.J., Na, M., Min, B.S., and Bae, K. (2009). Iridoid glycosides from Gardeniae fructus for treatment of ankle sprain. Phytochemistry 70, 779-784.
-
(2009)
Phytochemistry
, vol.70
, pp. 779-784
-
-
Chen, Q.C.1
Zhang, W.Y.2
Youn, U.3
Kim, H.4
Lee, I.5
Jung, H.J.6
Na, M.7
Min, B.S.8
Bae, K.9
-
13
-
-
75749084759
-
Effects of Gardeniae fructus extract and geniposide on promoting ligament cell proliferation and collagen synthesis
-
Chen, Q.C., Zhang, W.Y., Kim, H., Lee, I.S., Ding, Y., Youn, U.J., Lee, S.M., Na, M., Min, B.S., and Bae, K. (2010). Effects of Gardeniae fructus extract and geniposide on promoting ligament cell proliferation and collagen synthesis. Phytother. Res. 24, S1-S5.
-
(2010)
Phytother. Res.
, vol.24
, pp. S1-S5
-
-
Chen, Q.C.1
Zhang, W.Y.2
Kim, H.3
Lee, I.S.4
Ding, Y.5
Youn, U.J.6
Lee, S.M.7
Na, M.8
Min, B.S.9
Bae, K.10
-
14
-
-
0041589549
-
Pharmacological evaluation of several major ingredients of Chinese herbal medicines in human hepatoma Hep3B cells
-
Chou, C.C., Pan, S.L., Teng, C.M., and Guh, J.H. (2003). Pharmacological evaluation of several major ingredients of Chinese herbal medicines in human hepatoma Hep3B cells. Eur. J. Pharm. Sci. 19, 403-412.
-
(2003)
Eur. J. Pharm. Sci.
, vol.19
, pp. 403-412
-
-
Chou, C.C.1
Pan, S.L.2
Teng, C.M.3
Guh, J.H.4
-
15
-
-
84859242538
-
Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function
-
Ciron, C., Lengacher, S., Dusonchet, J., Aebischer, P., and Schneider, B.L. (2012). Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function. Hum. Mol. Genet. 21, 1861-1876.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 1861-1876
-
-
Ciron, C.1
Lengacher, S.2
Dusonchet, J.3
Aebischer, P.4
Schneider, B.L.5
-
16
-
-
84868379118
-
Drug repositioning for Alzheimers disease
-
Corbett, A., Pickett, J., Burns, A., Corcoran, J., Dunnett, S.B., Edison, P., Hagan, J.J., Holmes, C., Jones, E., Katona, C., et al. (2012). Drug repositioning for Alzheimers disease. Nat. Rev. Drug Discov. 11, 833-846.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 833-846
-
-
Corbett, A.1
Pickett, J.2
Burns, A.3
Corcoran, J.4
Dunnett, S.B.5
Edison, P.6
Hagan, J.J.7
Holmes, C.8
Jones, E.9
Katona, C.10
-
17
-
-
50949100957
-
Release of acetylcholinesterase (AChE) from β-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice
-
Dinamarca, M.C., Arrazola, M., Toledo, E., Cerpa, W.F., Hancke, J., and Inestrosa, N.C. (2008). Release of acetylcholinesterase (AChE) from β-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice. Chem. Biol. Interact. 175, 142-149.
-
(2008)
Chem. Biol. Interact.
, vol.175
, pp. 142-149
-
-
Dinamarca, M.C.1
Arrazola, M.2
Toledo, E.3
Cerpa, W.F.4
Hancke, J.5
Inestrosa, N.C.6
-
18
-
-
0022896901
-
τ protein function in living cells
-
Drubin, D.G. and Kirschner, M.W. (1986). τ protein function in living cells. J. Cell Biol. 103, 2739-2746.
-
(1986)
J. Cell Biol.
, vol.103
, pp. 2739-2746
-
-
Drubin, D.G.1
Kirschner, M.W.2
-
19
-
-
0032802629
-
Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice
-
Eldar-Finkelman, H., Schreyer, S.A., Shinohara, M.M., LeBoeuf, R.C., and Krebs, E.G. (1999). Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice. Diabetes 48, 1662-1666.
-
(1999)
Diabetes
, vol.48
, pp. 1662-1666
-
-
Eldar-Finkelman, H.1
Schreyer, S.A.2
Shinohara, M.M.3
LeBoeuf, R.C.4
Krebs, E.G.5
-
20
-
-
84980053538
-
ER-stress in Alzheimers disease: Turning the scale?
-
Endres, K. and Reinhardt, S. (2013). ER-stress in Alzheimers disease: turning the scale? Am. J. Neurodegener. Dis. 2, 247-265.
-
(2013)
Am. J. Neurodegener. Dis.
, vol.2
, pp. 247-265
-
-
Endres, K.1
Reinhardt, S.2
-
21
-
-
66349117317
-
Membrane phospholipid synthesis and endoplasmic reticulum function
-
Fagone, P. and Jackowski, S. (2009). Membrane phospholipid synthesis and endoplasmic reticulum function. J. Lipid Res. 50, S311-S316.
-
(2009)
J. Lipid Res.
, vol.50
, pp. S311-S316
-
-
Fagone, P.1
Jackowski, S.2
-
22
-
-
84928938613
-
Role of immunity and inflammation in the pathophysiology of neurodegenerative diseases
-
Epub ahead of print
-
Fakhoury, M. (2015). Role of immunity and inflammation in the pathophysiology of neurodegenerative diseases. Neurodegener. Dis. Epub ahead of print.
-
(2015)
Neurodegener. Dis.
-
-
Fakhoury, M.1
-
23
-
-
77951647591
-
RAGEdependent signaling in microglia contributes to neuroinflammation, Aβ accumulation, and impaired learning/memory in a mouse model of Alzheimers disease
-
Fang, F., Lue, L.F., Yan, S., Xu, H., Luddy, J.S., Chen, D., Walker, D.G., Stern, D.M., Schmidt, A.M., Chen, J.X., et al. (2010). RAGEdependent signaling in microglia contributes to neuroinflammation, Aβ accumulation, and impaired learning/memory in a mouse model of Alzheimers disease. FASEB J. 24, 1043-1055.
-
(2010)
FASEB J.
, vol.24
, pp. 1043-1055
-
-
Fang, F.1
Lue, L.F.2
Yan, S.3
Xu, H.4
Luddy, J.S.5
Chen, D.6
Walker, D.G.7
Stern, D.M.8
Schmidt, A.M.9
Chen, J.X.10
-
24
-
-
0034329543
-
Wood JG. Phosphorylation of human τ protein by microtubule-associated kinases: GSK3β and cdk5 are key participants
-
Flaherty, D.B., Soria, J.P., and Tomasiewicz, H.G. (2000). Wood JG. Phosphorylation of human τ protein by microtubule-associated kinases: GSK3β and cdk5 are key participants. J. Neurosci. Res. 62, 463-472.
-
(2000)
J. Neurosci. Res.
, vol.62
, pp. 463-472
-
-
Flaherty, D.B.1
Soria, J.P.2
Tomasiewicz, H.G.3
-
25
-
-
84918576232
-
Connecting the dots between τ dysfunction and neurodegeneration
-
Frost, B., Gotz, J., and Feany, M.B. (2015). Connecting the dots between τ dysfunction and neurodegeneration. Trends Cell Biol. 25, 46-53.
-
(2015)
Trends Cell Biol.
, vol.25
, pp. 46-53
-
-
Frost, B.1
Gotz, J.2
Feany, M.B.3
-
26
-
-
24644486061
-
Iridoids as DNA topoisomerase i poisons
-
Galvez, M., Martin-Cordero, C., and Ayuso, M.J. (2005). Iridoids as DNA topoisomerase I poisons. J. Enzyme Inhib. Med. Chem. 20, 389-392.
-
(2005)
J. Enzyme Inhib. Med. Chem.
, vol.20
, pp. 389-392
-
-
Galvez, M.1
Martin-Cordero, C.2
Ayuso, M.J.3
-
27
-
-
84860520259
-
GSK3: A key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease
-
Gao, C., Holscher, C., Liu, Y., and Li, L. (2011). GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease. Rev. Neurosci. 23, 1-11.
-
(2011)
Rev. Neurosci.
, vol.23
, pp. 1-11
-
-
Gao, C.1
Holscher, C.2
Liu, Y.3
Li, L.4
-
28
-
-
84898542999
-
Geniposide ameliorates learning memory deficits, reduces τ phosphorylation and decreases apoptosis via GSK3β pathway in streptozotocin-induced Alzheimer rat model
-
Gao, C., Liu, Y., Jiang, Y., Ding, J., and Li, L. (2014). Geniposide ameliorates learning memory deficits, reduces τ phosphorylation and decreases apoptosis via GSK3β pathway in streptozotocin-induced Alzheimer rat model. Brain Pathol. 24, 261-269.
-
(2014)
Brain Pathol.
, vol.24
, pp. 261-269
-
-
Gao, C.1
Liu, Y.2
Jiang, Y.3
Ding, J.4
Li, L.5
-
29
-
-
84898426102
-
Signaling pathway cross talk in Alzheimers disease
-
Godoy, J.A., Rios, J.A., Zolezzi, J.M., Braidy, N., and Inestrosa, N.C. (2014). Signaling pathway cross talk in Alzheimers disease. Cell Commun. Signal. 12, 23.
-
(2014)
Cell Commun. Signal.
, vol.12
, pp. 23
-
-
Godoy, J.A.1
Rios, J.A.2
Zolezzi, J.M.3
Braidy, N.4
Inestrosa, N.C.5
-
30
-
-
84900484028
-
Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors
-
Gong, N., Fan, H., Ma, A.N., Xiao, Q., and Wang, Y.X. (2014). Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors. Neuropharmacology 84, 31-45.
-
(2014)
Neuropharmacology
, vol.84
, pp. 31-45
-
-
Gong, N.1
Fan, H.2
Ma, A.N.3
Xiao, Q.4
Wang, Y.X.5
-
31
-
-
84857077700
-
τ-targeted treatment strategies in Alzheimers disease
-
Gotz, J., Ittner, A., and Ittner, L.M. (2012). τ-targeted treatment strategies in Alzheimers disease. Br. J. Pharmacol. 165, 1246-1259.
-
(2012)
Br. J. Pharmacol.
, vol.165
, pp. 1246-1259
-
-
Gotz, J.1
Ittner, A.2
Ittner, L.M.3
-
32
-
-
3042792777
-
Comparative effects of GLP-1 and GIP on cAMP production, insulin secretion, and in vivo antidiabetic actions following substitution of Ala8/Ala2 with 2-aminobutyric acid
-
Green, B.D., Gault, V.A., Flatt, P.R., Harriott, P., Greer, B., and OHarte, F.P. (2004). Comparative effects of GLP-1 and GIP on cAMP production, insulin secretion, and in vivo antidiabetic actions following substitution of Ala8/Ala2 with 2-aminobutyric acid. Arch. Biochem. Biophys. 428, 136-143.
-
(2004)
Arch. Biochem. Biophys.
, vol.428
, pp. 136-143
-
-
Green, B.D.1
Gault, V.A.2
Flatt, P.R.3
Harriott, P.4
Greer, B.5
OHarte, F.P.6
-
33
-
-
0023009658
-
Wisniewski HM. Microtubule-associated protein τ. A component of Alzheimer paired helical filaments
-
Grundke-Iqbal, I., Iqbal, K., Quinlan, M., Tung, Y.C., and Zaidi, M.S. (1986). Wisniewski HM. Microtubule-associated protein τ. A component of Alzheimer paired helical filaments. J. Biol. Chem. 261, 6084-6089.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 6084-6089
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Quinlan, M.3
Tung, Y.C.4
Zaidi, M.S.5
-
34
-
-
74549180462
-
Geniposide inhibits CoCl2- induced PC12 cells death via the mitochondrial pathway
-
Guo, L.X., Liu, J.H., and Xia, Z.N. (2009). Geniposide inhibits CoCl2- induced PC12 cells death via the mitochondrial pathway. Chin. Med. J. (Engl.) 122, 2886-2892.
-
(2009)
Chin. Med. J. (Engl.)
, vol.122
, pp. 2886-2892
-
-
Guo, L.X.1
Liu, J.H.2
Xia, Z.N.3
-
35
-
-
84863133805
-
Glucagonlike peptide 1 receptor plays a critical role in geniposideregulated insulin secretion in INS-1 cells
-
Guo, L.X., Xia, Z.N., Gao, X., Yin, F., and Liu, J.H. (2012). Glucagonlike peptide 1 receptor plays a critical role in geniposideregulated insulin secretion in INS-1 cells. Acta Pharmacol. Sin. 33, 237-241.
-
(2012)
Acta Pharmacol. Sin.
, vol.33
, pp. 237-241
-
-
Guo, L.X.1
Xia, Z.N.2
Gao, X.3
Yin, F.4
Liu, J.H.5
-
36
-
-
0038387243
-
Nitric oxide prevents 6-hydroxydopamine-induced apoptosis in PC12 cells through cGMP-dependent PI3 kinase/Akt activation
-
Ha, K.S., Kim, K.M., Kwon, Y.G., Bai, S.K., Nam, W.D., Yoo, Y.M., Kim, P.K., Chung, H.T., Billiar, T.R., and Kim, Y.M. (2003). Nitric oxide prevents 6-hydroxydopamine-induced apoptosis in PC12 cells through cGMP-dependent PI3 kinase/Akt activation. FASEB J. 17, 1036-1047.
-
(2003)
FASEB J.
, vol.17
, pp. 1036-1047
-
-
Ha, K.S.1
Kim, K.M.2
Kwon, Y.G.3
Bai, S.K.4
Nam, W.D.5
Yoo, Y.M.6
Kim, P.K.7
Chung, H.T.8
Billiar, T.R.9
Kim, Y.M.10
-
37
-
-
33644585223
-
Therapy insight: Type 2 diabetes mellitus and the risk of late-onset Alzheimers disease
-
Haan, M.N. (2006). Therapy insight: type 2 diabetes mellitus and the risk of late-onset Alzheimers disease. Nat. Clin. Pract. Neurol. 2, 159-166.
-
(2006)
Nat. Clin. Pract. Neurol.
, vol.2
, pp. 159-166
-
-
Haan, M.N.1
-
38
-
-
78649820608
-
Inhibitors of catalaseamyloid interactions protect cells from β-amyloid-induced oxidative stress and toxicity
-
Habib, L.K., Lee, M.T., and Yang, J. (2010). Inhibitors of catalaseamyloid interactions protect cells from β-amyloid-induced oxidative stress and toxicity. J. Biol. Chem. 285, 38933-38943.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 38933-38943
-
-
Habib, L.K.1
Lee, M.T.2
Yang, J.3
-
39
-
-
80054990445
-
Identification of metabolites of geniposide in rat urine using ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry
-
Han, H., Yang, L., Xu, Y., Ding, Y., Annie Bligh, S.W., Zhang, T., and Wang. Z.T. (2011). Identification of metabolites of geniposide in rat urine using ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Rapid Commun. Mass Spectrom. 25, 3339-3350.
-
(2011)
Rapid Commun. Mass Spectrom.
, vol.25
, pp. 3339-3350
-
-
Han, H.1
Yang, L.2
Xu, Y.3
Ding, Y.4
Annie Bligh, S.W.5
Zhang, T.6
Wang, Z.T.7
-
40
-
-
0024213874
-
Comparison of nerve growth factors effects on development of septum, striatum, and nucleus basalis cholinergic neurons in vitro
-
Hartikka, J. and Hefti, F. (1988). Comparison of nerve growth factors effects on development of septum, striatum, and nucleus basalis cholinergic neurons in vitro. J. Neurosci. Res. 21, 352-364.
-
(1988)
J. Neurosci. Res.
, vol.21
, pp. 352-364
-
-
Hartikka, J.1
Hefti, F.2
-
41
-
-
84871710082
-
Kinase-kinase interaction and modulation of τ phosphorylation
-
Hashiguchi, M. and Hashiguchi, T. (2013). Kinase-kinase interaction and modulation of τ phosphorylation. Int. Rev. Cell. Mol. Biol. 300, 121-160.
-
(2013)
Int. Rev. Cell. Mol. Biol.
, vol.300
, pp. 121-160
-
-
Hashiguchi, M.1
Hashiguchi, T.2
-
42
-
-
84903269246
-
Innate immune activation in neurodegenerative disease
-
Heneka, M.T., Kummer, M.P., and Latz, E. (2014). Innate immune activation in neurodegenerative disease. Nat. Rev. Immunol. 14, 463-477.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 463-477
-
-
Heneka, M.T.1
Kummer, M.P.2
Latz, E.3
-
43
-
-
79960152513
-
Alzheimers disease genetics: Current knowledge and future challenges
-
Hollingworth, P., Harold, D., Jones, L., Owen, M.J., and Williams, J. (2011). Alzheimers disease genetics: current knowledge and future challenges. Int. J. Geriatr. Psychiatry 26, 793-802.
-
(2011)
Int. J. Geriatr. Psychiatry
, vol.26
, pp. 793-802
-
-
Hollingworth, P.1
Harold, D.2
Jones, L.3
Owen, M.J.4
Williams, J.5
-
44
-
-
79960881826
-
Diabetes as a risk factor for Alzheimers disease: Insulin signalling impairment in the brain as an alternative model of Alzheimers disease
-
Holscher, C. (2011). Diabetes as a risk factor for Alzheimers disease: insulin signalling impairment in the brain as an alternative model of Alzheimers disease. Biochem. Soc. Trans. 39, 891-897.
-
(2011)
Biochem. Soc. Trans.
, vol.39
, pp. 891-897
-
-
Holscher, C.1
-
45
-
-
84897848470
-
Central effects of GLP-1: New opportunities for treatments of neurodegenerative diseases
-
Holscher, C. (2014a). Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases. J. Endocrinol. 221, T31-T41.
-
(2014)
J. Endocrinol.
, vol.221
, pp. T31-T41
-
-
Holscher, C.1
-
46
-
-
84929504903
-
Drugs developed for treatment of diabetes show protective effects in Alzheimers and Parkinsons diseases
-
Holscher, C. (2014b). Drugs developed for treatment of diabetes show protective effects in Alzheimers and Parkinsons diseases. Acta Physiol. Sin. 66, 497-510.
-
(2014)
Acta Physiol. Sin.
, vol.66
, pp. 497-510
-
-
Holscher, C.1
-
47
-
-
39849110726
-
The GSK3 hypothesis of Alzheimers disease
-
Hooper, C., Killick, R., and Lovestone, S. (2008). The GSK3 hypothesis of Alzheimers disease. J. Neurochem. 104, 1433-1439.
-
(2008)
J. Neurochem.
, vol.104
, pp. 1433-1439
-
-
Hooper, C.1
Killick, R.2
Lovestone, S.3
-
48
-
-
47149111967
-
Metabolism and pharmacokinetics of genipin and geniposide in rats
-
Hou, Y.C., Tsai, S.Y., Lai, P.Y., Chen, Y.S., and Chao, P.D.L. (2008). Metabolism and pharmacokinetics of genipin and geniposide in rats. Food Chem. Toxicol. 46, 2764-2769.
-
(2008)
Food Chem. Toxicol.
, vol.46
, pp. 2764-2769
-
-
Hou, Y.C.1
Tsai, S.Y.2
Lai, P.Y.3
Chen, Y.S.4
Chao, P.D.L.5
-
49
-
-
0031586739
-
Comparisons of geniposidic acid and geniposide on antitumor and radioprotection after sublethal irradiation
-
Hsu, H.Y., Yang, J.J., Lin, S.Y., and Lin, C.C. (1997). Comparisons of geniposidic acid and geniposide on antitumor and radioprotection after sublethal irradiation. Cancer Lett. 113, 31-37.
-
(1997)
Cancer Lett.
, vol.113
, pp. 31-37
-
-
Hsu, H.Y.1
Yang, J.J.2
Lin, S.Y.3
Lin, C.C.4
-
50
-
-
0041488911
-
TRK receptors: Roles in neuronal signal transduction
-
Huang, E.J. and Reichard, L.F. (2003). TRK receptors: roles in neuronal signal transduction. Annu. Rev. Biochem. 72, 609-642.
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 609-642
-
-
Huang, E.J.1
Reichard, L.F.2
-
51
-
-
84892374763
-
Effect of geniposide on LPS-induced activation of TLR4-NF-κB pathway in RAW264.7 macrophage cell line
-
Huang, L., Wang, C., Naren, G., and Aori, G. (2013). Effect of geniposide on LPS-induced activation of TLR4-NF-κB pathway in RAW264.7 macrophage cell line. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 29, 1012-1014.
-
(2013)
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
, vol.29
, pp. 1012-1014
-
-
Huang, L.1
Wang, C.2
Naren, G.3
Aori, G.4
-
52
-
-
84862833600
-
τ in Alzheimer disease and related tauopathies
-
Iqbal, K., Liu, F., Gong, C.X., and Grundke-Iqbal, I. (2010). τ in Alzheimer disease and related tauopathies. Curr. Alzheimer Res. 7, 656-664.
-
(2010)
Curr. Alzheimer Res.
, vol.7
, pp. 656-664
-
-
Iqbal, K.1
Liu, F.2
Gong, C.X.3
Grundke-Iqbal, I.4
-
53
-
-
79960880118
-
Assessing the contribution of inflammation in models of Alzheimers disease
-
Johnston, H., Boutin, H., and Allan, S.M. (2011). Assessing the contribution of inflammation in models of Alzheimers disease. Biochem. Soc. Trans. 39, 886-890.
-
(2011)
Biochem. Soc. Trans.
, vol.39
, pp. 886-890
-
-
Johnston, H.1
Boutin, H.2
Allan, S.M.3
-
54
-
-
0344672942
-
APP processing and synaptic function
-
Kamenetz, F., Tomita, T., Hsieh, H., Seabrook,G., Borcheit, D., Iwatsubo, T., Sisodia, S., and Malinow, R. (2003). APP processing and synaptic function. Neuron 37, 925-937.
-
(2003)
Neuron
, vol.37
, pp. 925-937
-
-
Kamenetz, F.1
Tomita, T.2
Seabrookg, H.H.3
Borcheit, D.4
Iwatsubo, T.5
Sisodia, S.6
Malinow, R.7
-
55
-
-
84886388885
-
Treadmill exercise represses neuronal cell death and inflammation during Aβ- induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice
-
Kang, E.B., Kwon, I.S., Koo, J.H., Kim, E.J., Kim, C.H., Lee, J., Yang, C.H., Lee, Y.I., Cho, I.H., and Cho, J.Y. (2013). Treadmill exercise represses neuronal cell death and inflammation during Aβ- induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice. Apoptosis 18, 1332-1347.
-
(2013)
Apoptosis
, vol.18
, pp. 1332-1347
-
-
Kang, E.B.1
Kwon, I.S.2
Koo, J.H.3
Kim, E.J.4
Kim, C.H.5
Lee, J.6
Yang, C.H.7
Lee, Y.I.8
Cho, I.H.9
Cho, J.Y.10
-
56
-
-
3042788976
-
Antiinflammatory effects of genipin, an active principle of gardenia
-
Koo, H.J., Song, Y.S., Kim, H.J., Lee, Y.H., Hong, S.M., Kim, S.J., Kim, B.C., Jin, C., Lim, C.J., and Park, E.H. (2004). Antiinflammatory effects of genipin, an active principle of gardenia. Eur. J. Pharmacol. 495, 201-208.
-
(2004)
Eur. J. Pharmacol.
, vol.495
, pp. 201-208
-
-
Koo, H.J.1
Song, Y.S.2
Kim, H.J.3
Lee, Y.H.4
Hong, S.M.5
Kim, S.J.6
Kim, B.C.7
Jin, C.8
Lim, C.J.9
Park, E.H.10
-
57
-
-
31344449552
-
Anti-inflammatory evaluation of gardenia extract, geniposide and genipin
-
Koo, H.J., Lim, K.H., Jung, H.J., and Park, E.H. (2006). Anti-inflammatory evaluation of gardenia extract, geniposide and genipin. J. Ethnopharmacol. 103, 496-500.
-
(2006)
J. Ethnopharmacol.
, vol.103
, pp. 496-500
-
-
Koo, H.J.1
Lim, K.H.2
Jung, H.J.3
Park, E.H.4
-
58
-
-
25444440828
-
Geniposide activates GSH S-transferase by the induction of GST M1 and GST M2 subunits involving the transcription and phosphorylation of MEK-1 signaling in rat hepatocytes
-
Kuo, W.H., Chou, F.P., Young, S.C., Chang, Y.C., and Wang, C.J. (2005). Geniposide activates GSH S-transferase by the induction of GST M1 and GST M2 subunits involving the transcription and phosphorylation of MEK-1 signaling in rat hepatocytes. Toxicol. Appl. Pharm. 208, 155-162.
-
(2005)
Toxicol. Appl. Pharm.
, vol.208
, pp. 155-162
-
-
Kuo, W.H.1
Chou, F.P.2
Young, S.C.3
Chang, Y.C.4
Wang, C.J.5
-
59
-
-
77955971635
-
The S100B/RAGE axis in Alzheimers disease
-
Leclerc, E., Sturchler, E., and Vetter, S. (2010). The S100B/RAGE axis in Alzheimers disease. Cardiovasc. Psychiatry Neurol. 2010, 1-11.
-
(2010)
Cardiovasc. Psychiatry Neurol.
, vol.2010
, pp. 1-11
-
-
Leclerc, E.1
Sturchler, E.2
Vetter, S.3
-
60
-
-
77954202499
-
Antioxidant approaches for the treatment of Alzheimers disease
-
Lee, H.P., Zhu, X., Casadesus, G., Castellani, R.J., Nunomura, A., Smith, M.A., Lee, H.G., and Perry, G. (2010). Antioxidant approaches for the treatment of Alzheimers disease. Expert Rev. Neurother. 10, 1201-1208.
-
(2010)
Expert Rev. Neurother.
, vol.10
, pp. 1201-1208
-
-
Lee, H.P.1
Zhu, X.2
Casadesus, G.3
Castellani, R.J.4
Nunomura, A.5
Smith, M.A.6
Lee, H.G.7
Perry, G.8
-
61
-
-
84892594440
-
Eucommia ulmoides Oliver extract, aucubin, and geniposide enhance lysosomal activity to regulate ER stress and hepatic lipid accumulation
-
Lee, H.Y., Lee, G.H., Lee, M.R., Kim, H.K., Kim, N.Y., Kim, S.H., Lee, Y.C., Kim, H.R., and Chae, H.J. (2013). Eucommia ulmoides Oliver extract, aucubin, and geniposide enhance lysosomal activity to regulate ER stress and hepatic lipid accumulation. PLoS One 8, e81349.
-
(2013)
PLoS One
, vol.8
, pp. e81349
-
-
Lee, H.Y.1
Lee, G.H.2
Lee, M.R.3
Kim, H.K.4
Kim, N.Y.5
Kim, S.H.6
Lee, Y.C.7
Kim, H.R.8
Chae, H.J.9
-
62
-
-
36448936053
-
Common pathological processes in Alzheimer disease and type 2 diabetes: A review
-
Li, L. and Holscher, C. (2007). Common pathological processes in Alzheimer disease and type 2 diabetes: a review. Brain Res. Rev. 56, 384-402.
-
(2007)
Brain Res. Rev.
, vol.56
, pp. 384-402
-
-
Li, L.1
Holscher, C.2
-
63
-
-
77950352189
-
GLP-1 receptor stimulation reduces amyloid-β peptide accumulation and cytotoxicity in cellular and animal models of Alzheimers disease
-
Li, Y., Duffy, K.B., Ottinger, M.A., Ray, B., Bailey, J.A., Holloway, H.W., Tweedie, D., Perry, T., Mattson, M.P., Kapogiannis, D., et al. (2010). GLP-1 receptor stimulation reduces amyloid-β peptide accumulation and cytotoxicity in cellular and animal models of Alzheimers disease. J. Alzheimers Dis. 19, 1205-1219.
-
(2010)
J. Alzheimers Dis.
, vol.19
, pp. 1205-1219
-
-
Li, Y.1
Duffy, K.B.2
Ottinger, M.A.3
Ray, B.4
Bailey, J.A.5
Holloway, H.W.6
Tweedie, D.7
Perry, T.8
Mattson, M.P.9
Kapogiannis, D.10
-
64
-
-
33750066662
-
Neurotrophic property of geniposide for inducing the neuronal differentiation of PC12 cells
-
Liu, J., Zheng, X., Yin, F., Hu, Y., Guo, L., Deng, X., Chen, G., Jiajia, J., and Zhang, H. (2006). Neurotrophic property of geniposide for inducing the neuronal differentiation of PC12 cells. Int. J. Dev. Neurosci. 24, 419-424.
-
(2006)
Int. J. Dev. Neurosci.
, vol.24
, pp. 419-424
-
-
Liu, J.1
Zheng, X.2
Yin, F.3
Hu, Y.4
Guo, L.5
Deng, X.6
Chen, G.7
Jiajia, J.8
Zhang, H.9
-
65
-
-
34848901678
-
Geniposide, a novel agonist for GLP-1 receptor, prevents PC12 cells from oxidative damage via MAP kinase pathway
-
Liu, J., Yin, F., Zheng, X., Jing, J., and Hu, Y. (2007). Geniposide, a novel agonist for GLP-1 receptor, prevents PC12 cells from oxidative damage via MAP kinase pathway. Neurochem. Int. 51, 361-369.
-
(2007)
Neurochem. Int.
, vol.51
, pp. 361-369
-
-
Liu, J.1
Yin, F.2
Zheng, X.3
Jing, J.4
Hu, Y.5
-
66
-
-
65349142455
-
Neuroprotection of geniposide against hydrogen peroxide induced PC12 cells injury: Involvement of PI3 kinase signal pathway
-
Liu, J.H., Yin, F., Guo, L.X., Deng, X.H., and Hu, Y.H. (2009). Neuroprotection of geniposide against hydrogen peroxide induced PC12 cells injury: involvement of PI3 kinase signal pathway. Acta Pharmacol. Sin. 30, 159-165.
-
(2009)
Acta Pharmacol. Sin.
, vol.30
, pp. 159-165
-
-
Liu, J.H.1
Yin, F.2
Guo, L.X.3
Deng, X.H.4
Hu, Y.H.5
-
67
-
-
77953324904
-
Geniposide inhibits interleukin-6 and interleukin- 8 production in lipopolysaccharide-induced human umbilical vein endothelial cells by blocking p38 and ERK1/2 signaling pathways
-
Liu, H.T., He, J.L., Li, W.M., Yang, Z., Wang, Y.X., Yin, J., Du, Y.G., and Yu, C. (2010). Geniposide inhibits interleukin-6 and interleukin- 8 production in lipopolysaccharide-induced human umbilical vein endothelial cells by blocking p38 and ERK1/2 signaling pathways. Inflamm. Res. 59, 451-461.
-
(2010)
Inflamm. Res.
, vol.59
, pp. 451-461
-
-
Liu, H.T.1
He, J.L.2
Li, W.M.3
Yang, Z.4
Wang, Y.X.5
Yin, J.6
Du, Y.G.7
Yu, C.8
-
68
-
-
84866053595
-
Glucagon-like peptide 1 receptor plays an essential role in geniposide attenuating lipotoxicity-induced β-cell apoptosis
-
Liu, J., Yin, F., Xiao, H., Guo, L., and Gao, X. (2012). Glucagon-like peptide 1 receptor plays an essential role in geniposide attenuating lipotoxicity-induced β-cell apoptosis. Toxicol. In Vitro 26, 1093-1097.
-
(2012)
Toxicol. in Vitro
, vol.26
, pp. 1093-1097
-
-
Liu, J.1
Yin, F.2
Xiao, H.3
Guo, L.4
Gao, X.5
-
69
-
-
84901417472
-
GSK-3β, a pivotal kinase in Alzheimer disease
-
Llorens-Martin, M., Jurado, J., Hern?dez, F., and Avila, J. (2014). GSK-3β, a pivotal kinase in Alzheimer disease. Front. Mol. Neurosci. 7, 46.
-
(2014)
Front. Mol. Neurosci.
, vol.7
, pp. 46
-
-
Llorens-Martin, M.1
Jurado, J.2
Herndez, F.3
Avila, J.4
-
70
-
-
0034840664
-
Involvement of microglial receptor for advanced glycation end products (RAGE) in Alzheimers disease: Identification of a cellular activation mechanism
-
Lue, L.F., Walker, D.G., Brachova, L., Beach, T.G., Rogers, J., Schmidt, A.M., Stem, D.M., and Yan, S.D. (2001). Involvement of microglial receptor for advanced glycation end products (RAGE) in Alzheimers disease: identification of a cellular activation mechanism. Exp. Neurol. 171, 29-45.
-
(2001)
Exp. Neurol.
, vol.171
, pp. 29-45
-
-
Lue, L.F.1
Walker, D.G.2
Brachova, L.3
Beach, T.G.4
Rogers, J.5
Schmidt, A.M.6
Stem, D.M.7
Yan, S.D.8
-
71
-
-
84904760940
-
Geniposide attenuates mitochondrial dysfunction and memory deficits in APP/PS1 transgenic mice
-
Lv, C., Liu, X., Liu, H., Chen, T., and Zhang, W. (2014). Geniposide attenuates mitochondrial dysfunction and memory deficits in APP/PS1 transgenic mice. Curr. Alzheimer Res. 11, 580-587.
-
(2014)
Curr. Alzheimer Res.
, vol.11
, pp. 580-587
-
-
Lv, C.1
Liu, X.2
Liu, H.3
Chen, T.4
Zhang, W.5
-
72
-
-
84922334209
-
Multi-faced neuroprotective effects of geniposide depending on the RAGE-mediated signaling in an Alzheimer mouse model
-
Lv, C., Wang, L., Liu, X., Yan, S., Yan, S.S., Wang, Y., and Zhang, W. (2015). Multi-faced neuroprotective effects of geniposide depending on the RAGE-mediated signaling in an Alzheimer mouse model. Neuropharmacology 89, 175-184.
-
(2015)
Neuropharmacology
, vol.89
, pp. 175-184
-
-
Lv, C.1
Wang, L.2
Liu, X.3
Yan, S.4
Yan, S.S.5
Wang, Y.6
Zhang, W.7
-
73
-
-
79952715994
-
Hepatoprotective effects of geniposide in a rat model of nonalcoholic steatohepatitis
-
Ma, T., Huang, C., Zong, G., Zha, D., Meng, X., Li, J., and Tang, W. (2011). Hepatoprotective effects of geniposide in a rat model of nonalcoholic steatohepatitis. J. Pharm. Pharmacol. 63, 587-593.
-
(2011)
J. Pharm. Pharmacol.
, vol.63
, pp. 587-593
-
-
Ma, T.1
Huang, C.2
Zong, G.3
Zha, D.4
Meng, X.5
Li, J.6
Tang, W.7
-
74
-
-
84915820956
-
Resveratrol as a therapeutic agent for Alzheimers disease
-
Ma, T., Tan, M., Yu, J., and Tan, L. (2014). Resveratrol as a therapeutic agent for Alzheimers disease. Biomed. Res. Int. 2014, 350516.
-
(2014)
Biomed. Res. Int.
, vol.2014
, pp. 350516
-
-
Ma, T.1
Tan, M.2
Yu, J.3
Tan, L.4
-
75
-
-
34848921838
-
Impact of amyloid imaging on drug development in Alzheimers disease
-
Mathis, C.A., Lopresti, B.J., and Klunk, W.E. (2007). Impact of amyloid imaging on drug development in Alzheimers disease. Nucl. Med. Biol. 34, 809-22.
-
(2007)
Nucl. Med. Biol.
, vol.34
, pp. 809-822
-
-
Mathis, C.A.1
Lopresti, B.J.2
Klunk, W.E.3
-
76
-
-
57349112359
-
Neuro2a cell death induced by 6-hydroxydopamine is attenuated by genipin
-
Matsumi, Y., Kenzo, C., and Keiko, S. (2008). Neuro2a cell death induced by 6-hydroxydopamine is attenuated by genipin. J. Health Sci. 54, 638-644.
-
(2008)
J. Health Sci.
, vol.54
, pp. 638-644
-
-
Matsumi, Y.1
Kenzo, C.2
Keiko, S.3
-
77
-
-
79955749452
-
The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimers disease
-
McClean, P.L., Parthsarathy, V., Faivre, E., and Holscher, C. (2011). The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimers disease. J. Neurosci. 31, 6587-6594.
-
(2011)
J. Neurosci.
, vol.31
, pp. 6587-6594
-
-
McClean, P.L.1
Parthsarathy, V.2
Faivre, E.3
Holscher, C.4
-
78
-
-
84886592674
-
Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer s disease
-
McClean, P.L. and Holscher, C. (2014a). Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer s disease. Neuropharmacol. 76, 57-67.
-
(2014)
Neuropharmacol
, vol.76
, pp. 57-67
-
-
McClean, P.L.1
Holscher, C.2
-
79
-
-
84907302200
-
Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer s disease
-
McClean, P.L. and Holscher, C. (2014b). Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer s disease. Neuropharmacol. 86, 241-258.
-
(2014)
Neuropharmacol
, vol.86
, pp. 241-258
-
-
McClean, P.L.1
Holscher, C.2
-
80
-
-
0023789193
-
Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinsons and Alzheimers disease brains
-
McGeer, P.L., Itagaki, S., Boyes, B.E., and McGeer, E.G. (1988). Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinsons and Alzheimers disease brains. Neurology 38, 1285-1291.
-
(1988)
Neurology
, vol.38
, pp. 1285-1291
-
-
McGeer, P.L.1
Itagaki, S.2
Boyes, B.E.3
McGeer, E.G.4
-
81
-
-
79956298780
-
Glycogen synthase kinse-3 regulates endoplasmic reticulum (ER) stress-induced CHOP expression in neuronal cells
-
Meares, G.P., Mines, M.A., Beurel, E., Eom, T.Y., Song, L., Zmijewska, A.A., and Jope, R.S. (2011). Glycogen synthase kinse-3 regulates endoplasmic reticulum (ER) stress-induced CHOP expression in neuronal cells. Exp. Cell Res. 317, 1621-1628.
-
(2011)
Exp. Cell Res.
, vol.317
, pp. 1621-1628
-
-
Meares, G.P.1
Mines, M.A.2
Beurel, E.3
Eom, T.Y.4
Song, L.5
Zmijewska, A.A.6
Jope, R.S.7
-
82
-
-
0028953529
-
Activation of microglial cells by β-amyloid protein and interferon- γ
-
Meda, L., Cassatella, M.A., Szendrei, G.I., Otvos, L. Jr., Baron, P., Villalba, M., Ferrari, D., and Rossi, F. (1995). Activation of microglial cells by β-amyloid protein and interferon- γ. Nature 374, 647-650.
-
(1995)
Nature
, vol.374
, pp. 647-650
-
-
Meda, L.1
Cassatella, M.A.2
Szendrei, G.I.3
Otvos, L.4
Baron, P.5
Villalba, M.6
Ferrari, D.7
Rossi, F.8
-
83
-
-
84897954153
-
New perspectives on the role of τ in Alzheimers disease. Implications for therapy
-
Medina, M. and Avila, J. (2014). New perspectives on the role of τ in Alzheimers disease. Implications for therapy. Biochem. Pharmacol. 88, 540-547.
-
(2014)
Biochem. Pharmacol.
, vol.88
, pp. 540-547
-
-
Medina, M.1
Avila, J.2
-
84
-
-
84922479199
-
Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimers disease
-
Morris, G.P., Clark, I.A., and Vissel, B. (2014). Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimers disease. Acta Neuropathol. Commun. 2, 135.
-
(2014)
Acta Neuropathol. Commun.
, vol.2
, pp. 135
-
-
Morris, G.P.1
Clark, I.A.2
Vissel, B.3
-
85
-
-
34247494679
-
Endoplasmic reticulum stress response in dendrites of cultured primary neurons
-
Murakami, T., Hino, S.I., Saito, A., and Imaizumi, K. (2007). Endoplasmic reticulum stress response in dendrites of cultured primary neurons. Neuroscience 146, 1-8.
-
(2007)
Neuroscience
, vol.146
, pp. 1-8
-
-
Murakami, T.1
Hino, S.I.2
Saito, A.3
Imaizumi, K.4
-
86
-
-
27844458139
-
Insulin and cholesterol pathways in neuronal function, memory and neurodegeneration
-
Nelson, T.J. and Alkon, D.I. (2005). Insulin and cholesterol pathways in neuronal function, memory and neurodegeneration. Biochem. Soc. Trans. 33, 1033-1036.
-
(2005)
Biochem. Soc. Trans.
, vol.33
, pp. 1033-1036
-
-
Nelson, T.J.1
Alkon, D.I.2
-
87
-
-
84897890162
-
Study on integrated pharmacokinetics of gardenia acid and geniposide: Time-antioxidant efficacy after oral administration of Huanglian-Zhizi couplet medicine from Huang-Lian-Jie-Du-Tang in MCAO rats
-
Pan, L., Zhou, J., Zhu, H., Wang, W., Zhang, M., Tian, X., Lu, J., and Zeng, M. (2014). Study on integrated pharmacokinetics of gardenia acid and geniposide: time-antioxidant efficacy after oral administration of Huanglian-Zhizi couplet medicine from Huang-Lian-Jie-Du-Tang in MCAO rats. Am. J. Chin. Med. 42, 393-407.
-
(2014)
Am. J. Chin. Med.
, vol.42
, pp. 393-407
-
-
Pan, L.1
Zhou, J.2
Zhu, H.3
Wang, W.4
Zhang, M.5
Tian, X.6
Lu, J.7
Zeng, M.8
-
88
-
-
78650637178
-
Amyloid-β as a modulator of synaptic plasticity
-
Parihar, M.S. and Brewer, G.J. (2010). Amyloid-β as a modulator of synaptic plasticity. J. Alzheimers Dis. 22, 741-763.
-
(2010)
J. Alzheimers Dis.
, vol.22
, pp. 741-763
-
-
Parihar, M.S.1
Brewer, G.J.2
-
89
-
-
0035369840
-
Trk receptors: Mediators of neurotrophin action
-
Patapoutian, A. and Reichardt, L.F. (2001). Trk receptors: mediators of neurotrophin action. Curr. Opin. Neurobiol. 11, 272-280.
-
(2001)
Curr. Opin. Neurobiol.
, vol.11
, pp. 272-280
-
-
Patapoutian, A.1
Reichardt, L.F.2
-
90
-
-
22144491473
-
Enhancing central nervous system endogenous GLP-1 receptor pathways for intervention in Alzheimers disease
-
Perry, T. and Greig, N.H. (2005). Enhancing central nervous system endogenous GLP-1 receptor pathways for intervention in Alzheimers disease. Curr. Alzheimer Res. 2, 377-385.
-
(2005)
Curr. Alzheimer Res.
, vol.2
, pp. 377-385
-
-
Perry, T.1
Greig, N.H.2
-
91
-
-
0036182251
-
A novel neurotrophic property of glucagonlike peptide 1: A promoter of nerve growth factor-mediated differentiation in PC12 cells
-
Perry, T., Lahiri, D.K., Chen, D., Zhou, J., Shaw, K.T., Egan, J.M., and Greig, N.H. (2002). A novel neurotrophic property of glucagonlike peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells. J. Pharmacol. Exp. Ther. 300, 958-966.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.300
, pp. 958-966
-
-
Perry, T.1
Lahiri, D.K.2
Chen, D.3
Zhou, J.4
Shaw, K.T.5
Egan, J.M.6
Greig, N.H.7
-
92
-
-
0038248960
-
Glucagon-like peptide-1 decreases endogenous amyloid β peptide (Aβ) levels and protects hippocampal neurons from death induced by Aβ and iron
-
Perry, T., Lahiri, D.K., Sambamurti, K., Chen, D., Mattson, M.P., Egan, J.M., and Greig, N.H. (2003). Glucagon-like peptide-1 decreases endogenous amyloid β peptide (Aβ) levels and protects hippocampal neurons from death induced by Aβ and iron. J. Neurosci. Res. 72, 603-612.
-
(2003)
J. Neurosci. Res.
, vol.72
, pp. 603-612
-
-
Perry, T.1
Lahiri, D.K.2
Sambamurti, K.3
Chen, D.4
Mattson, M.P.5
Egan, J.M.6
Greig, N.H.7
-
93
-
-
84867571826
-
Mitochondria and Alzheimers disease
-
Piaceri, I., Rinnoci, V., Bagnoli, S., Failli, Y., and Sorbi, S. (2012). Mitochondria and Alzheimers disease. J. Neurol. Sci. 322, 31-34.
-
(2012)
J. Neurol. Sci.
, vol.322
, pp. 31-34
-
-
Piaceri, I.1
Rinnoci, V.2
Bagnoli, S.3
Failli, Y.4
Sorbi, S.5
-
94
-
-
60349125886
-
Reassessing the amyloid cascade hypothesis of Alzheimers disease
-
Pimplikar, S.W. (2009). Reassessing the amyloid cascade hypothesis of Alzheimers disease. Int. J. Biochem. Cell Biol. 41, 1261-1268.
-
(2009)
Int. J. Biochem. Cell Biol.
, vol.41
, pp. 1261-1268
-
-
Pimplikar, S.W.1
-
95
-
-
0037012844
-
Axonal self-destruction and neurodegeneration
-
Raff, M.C., Whitmore, A.V., and Finn, J.T. (2002). Axonal self-destruction and neurodegeneration. Science 296, 868-871.
-
(2002)
Science
, vol.296
, pp. 868-871
-
-
Raff, M.C.1
Whitmore, A.V.2
Finn, J.T.3
-
96
-
-
84872559990
-
Molecular mechanisms of amyloid oligomers toxicity
-
Rakez, K. and Cristian, A.L.R. (2013). Molecular mechanisms of amyloid oligomers toxicity. J. Alzheimers Dis. 33, s67-s78.
-
(2013)
J. Alzheimers Dis.
, vol.33
, pp. s67-s78
-
-
Rakez, K.1
Cristian, A.L.R.2
-
97
-
-
3543067962
-
Neurodegenerative disorders associated with diabetes mellitus
-
Ristow, M. (2004). Neurodegenerative disorders associated with diabetes mellitus. J. Mol. Med. 82, 510-529.
-
(2004)
J. Mol. Med.
, vol.82
, pp. 510-529
-
-
Ristow, M.1
-
98
-
-
84861078831
-
A review: Inflammatory process in Alzheimers disease, role of cytokines
-
Rubio-Perez, J.M. and Morillas-Ruiz, J.M. (2012). A review: inflammatory process in Alzheimers disease, role of cytokines. Sci. World J. 2012, 756357.
-
(2012)
Sci. World J.
, vol.2012
, pp. 756357
-
-
Rubio-Perez, J.M.1
Morillas-Ruiz, J.M.2
-
99
-
-
0034489963
-
Amyloid-β and treatment opportunities for Alzheimers disease
-
Sabbagh, M.N., Galasko, D., Koo, E., and Thal, L.J. (2000). Amyloid-β and treatment opportunities for Alzheimers disease. J. Alzheimers Dis. 2, 231-259.
-
(2000)
J. Alzheimers Dis.
, vol.2
, pp. 231-259
-
-
Sabbagh, M.N.1
Galasko, D.2
Koo, E.3
Thal, L.J.4
-
100
-
-
78149262655
-
Endoplasmic reticulum stress in agerelated macular degeneration: Trigger for neovascularization
-
Salminen, A., Kauppinen, A., Hyttinen, J.M., Toropainen, E., and Kaarniranta, K. (2010). Endoplasmic reticulum stress in agerelated macular degeneration: trigger for neovascularization. Mol. Med. 16, 535-542.
-
(2010)
Mol. Med.
, vol.16
, pp. 535-542
-
-
Salminen, A.1
Kauppinen, A.2
Hyttinen, J.M.3
Toropainen, E.4
Kaarniranta, K.5
-
101
-
-
77950860036
-
Intracellular Ca2+ storage in health and disease: A dynamic equilibrium
-
Sammels, E., Parys, J.B., Missiaen, L., De Smedt, H., and Bultynck, G. (2010). Intracellular Ca2+ storage in health and disease: a dynamic equilibrium. Cell Calcium 47, 297-314.
-
(2010)
Cell Calcium
, vol.47
, pp. 297-314
-
-
Sammels, E.1
Parys, J.B.2
Missiaen, L.3
De Smedt, H.4
Bultynck, G.5
-
102
-
-
44549087765
-
Soluble oligomers of the amyloid-β protein impair synaptic plasticity and behavior
-
Selkoe, D.J. (2008). Soluble oligomers of the amyloid-β protein impair synaptic plasticity and behavior. Behav. Brain Res. 192, 106-113.
-
(2008)
Behav. Brain Res.
, vol.192
, pp. 106-113
-
-
Selkoe, D.J.1
-
103
-
-
78651323561
-
SREBP-1c, Pdx-1, and GLP-1R involved in palmitate-EPA regulated glucosestimulated insulin secretion in INS-1 cells
-
Shao, S., Liu, Z., Yang, Y., Zhang, M., and Yu, X. (2010). SREBP-1c, Pdx-1, and GLP-1R involved in palmitate-EPA regulated glucosestimulated insulin secretion in INS-1 cells. J. Cell. Biochem. 111, 634-642.
-
(2010)
J. Cell. Biochem.
, vol.111
, pp. 634-642
-
-
Shao, S.1
Liu, Z.2
Yang, Y.3
Zhang, M.4
Yu, X.5
-
104
-
-
84897003731
-
Neuroprotective and anti-apoptotic effects of liraglutide on SH-SY5Y cells exposed to methylglyoxal stress
-
Sharma, M., Jalewa, J., and Holscher, C. (2013). Neuroprotective and anti-apoptotic effects of liraglutide on SH-SY5Y cells exposed to methylglyoxal stress. J. Neurochem. 128, 459-471.
-
(2013)
J. Neurochem.
, vol.128
, pp. 459-471
-
-
Sharma, M.1
Jalewa, J.2
Holscher, C.3
-
105
-
-
84918769608
-
Geniposide plays an anti-inflammatory role via regulating TLR4 and downstream signaling pathways in lipopolysaccharide-induced mastitis in mice
-
Song, X., Zhang, W., Wang, T., Jiang, H., Zhang, Z., Fu, Y., Yang, Z., Cao, Y., and Zhang, N. (2014). Geniposide plays an anti-inflammatory role via regulating TLR4 and downstream signaling pathways in lipopolysaccharide-induced mastitis in mice. Inflammation 37, 1588-1598.
-
(2014)
Inflammation
, vol.37
, pp. 1588-1598
-
-
Song, X.1
Zhang, W.2
Wang, T.3
Jiang, H.4
Zhang, Z.5
Fu, Y.6
Yang, Z.7
Cao, Y.8
Zhang, N.9
-
106
-
-
0032983536
-
Association of microglia with amyloid plaques in brains of APP23 transgenic mice
-
Stalder, M., Phinney, A., Probst, A., Sommer, B., Staufenbiel, M., and Jucker, M. (1999). Association of microglia with amyloid plaques in brains of APP23 transgenic mice. Am. J. Pathol. 154, 1673-1684.
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 1673-1684
-
-
Stalder, M.1
Phinney, A.2
Probst, A.3
Sommer, B.4
Staufenbiel, M.5
Jucker, M.6
-
107
-
-
84872337044
-
Neuroinflammatory phenotype in early Alzheimers disease
-
Sudduth, T.L., Schmitt, F.A., Nelson, P.T., and Wilcock, D.M. (2013). Neuroinflammatory phenotype in early Alzheimers disease. Neurobiol. Aging 34, 1051-1059.
-
(2013)
Neurobiol. Aging
, vol.34
, pp. 1051-1059
-
-
Sudduth, T.L.1
Schmitt, F.A.2
Nelson, P.T.3
Wilcock, D.M.4
-
108
-
-
84855704845
-
Pharmacokinetics of geniposide in Zhi-Zi-Hou-Pu decoction and in different combinations of its constituent herbs
-
Sun, Y., Feng, F., and Yu, X. (2012). Pharmacokinetics of geniposide in Zhi-Zi-Hou-Pu decoction and in different combinations of its constituent herbs. Phytother. Res. 26, 67-72.
-
(2012)
Phytother. Res.
, vol.26
, pp. 67-72
-
-
Sun, Y.1
Feng, F.2
Yu, X.3
-
109
-
-
84904501407
-
Efficacy and safety of donepezil, galantamine, rivastigmine, and memantine for the treatment of Alzheimers disease: A systematic review and meta-analysis
-
Tan, C.C., Yu, J.T., Wang, H.F., Tan, M.S., Meng, X.F., Wang, C., Jiang, T., Zhu, X.C., and Tan, L. (2014). Efficacy and safety of donepezil, galantamine, rivastigmine, and memantine for the treatment of Alzheimers disease: a systematic review and meta-analysis. J. Alzheimers Dis. 41, 615-631.
-
(2014)
J. Alzheimers Dis.
, vol.41
, pp. 615-631
-
-
Tan, C.C.1
Yu, J.T.2
Wang, H.F.3
Tan, M.S.4
Meng, X.F.5
Wang, C.6
Jiang, T.7
Zhu, X.C.8
Tan, L.9
-
110
-
-
67650751098
-
Neuroprotective action of genipin on tunicamycin-induced cytotoxicity in neuro2a cells
-
Tanaka, M., Yamazaki, M., and Chiba, K. (2009). Neuroprotective action of genipin on tunicamycin-induced cytotoxicity in neuro2a cells. Biol. Pharm. Bull. 32, 1220-1223.
-
(2009)
Biol. Pharm. Bull.
, vol.32
, pp. 1220-1223
-
-
Tanaka, M.1
Yamazaki, M.2
Chiba, K.3
-
111
-
-
0036047004
-
Axonal transport, τ protein, and neurodegeneration in Alzheimers disease
-
Terwel, D., Dewachter, I., and Van Leuven, F. (2002). Axonal transport, τ protein, and neurodegeneration in Alzheimers disease. Neuromol. Med. 2, 151-165.
-
(2002)
Neuromol. Med.
, vol.2
, pp. 151-165
-
-
Terwel, D.1
Dewachter, I.2
Van Leuven, F.3
-
112
-
-
57649221135
-
Amyloid precursor protein trafficking, processing, and function
-
Thinakaran, G. and Koo, E.H. (2008). Amyloid precursor protein trafficking, processing, and function. J. Biol. Chem. 283, 29615-29619.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 29615-29619
-
-
Thinakaran, G.1
Koo, E.H.2
-
113
-
-
84938744930
-
ER stress signaling and neurodegeneration: At the intersection between Alzheimers disease and prion-related disorders
-
DOI: 10.1016/j.virusres. 2014.12.018
-
Torres, M., Matamala, J.M., Duran-Aniotz, C., Cornejo, V.H., Foley, A., and Hetz, C. (2014). ER stress signaling and neurodegeneration: at the intersection between Alzheimers disease and prion-related disorders. Virus Res. DOI: 10.1016/j.virusres. 2014.12.018.
-
(2014)
Virus Res.
-
-
Torres, M.1
Matamala, J.M.2
Duran-Aniotz, C.3
Cornejo, V.H.4
Foley, A.5
Hetz, C.6
-
114
-
-
0034755677
-
Simultaneous estimation of geniposide and genipin in mouse plasma using high-performance liquid chromatography
-
Ueno, K., Takeda, Y., Iwasaki, Y., and Yoshizaki, F. (2001). Simultaneous estimation of geniposide and genipin in mouse plasma using high-performance liquid chromatography. Anal. Sci. 17, 1237-1239.
-
(2001)
Anal. Sci.
, vol.17
, pp. 1237-1239
-
-
Ueno, K.1
Takeda, Y.2
Iwasaki, Y.3
Yoshizaki, F.4
-
115
-
-
0026672278
-
Inhibitory effect of geniposide on aflatoxin B1-induced DNA repair synthesis in primary cultured rat hepatocytes
-
Wang, S.W., Lai, C.Y., and Wang, C.J. (1992). Inhibitory effect of geniposide on aflatoxin B1-induced DNA repair synthesis in primary cultured rat hepatocytes. Cancer Lett. 65, 133-137.
-
(1992)
Cancer Lett.
, vol.65
, pp. 133-137
-
-
Wang, S.W.1
Lai, C.Y.2
Wang, C.J.3
-
116
-
-
77957126457
-
Val8-glucagon-like peptide-1 protects against Aβ1-40- induced impairment of hippocampal late-phase long-term potentiation and spatial learning in rats
-
Wang, X.H., Li, L., Holscher, C., Pan, Y.F., Chen, X.R., and Qi, J.S. (2010). Val8-glucagon-like peptide-1 protects against Aβ1-40- induced impairment of hippocampal late-phase long-term potentiation and spatial learning in rats. Neuroscience 170, 1239-1248.
-
(2010)
Neuroscience
, vol.170
, pp. 1239-1248
-
-
Wang, X.H.1
Li, L.2
Holscher, C.3
Pan, Y.F.4
Chen, X.R.5
Qi, J.S.6
-
117
-
-
84866735550
-
Geniposide reduces inflammatory responses of oxygen-glucose deprived rat microglial cells via inhibition of the TLR4 signaling pathway
-
Wang, J., Hou, J., Zhang, P., Li, D., Zhang, C., and Liu, J. (2012a). Geniposide reduces inflammatory responses of oxygen-glucose deprived rat microglial cells via inhibition of the TLR4 signaling pathway. Neurochem. Res. 37, 2235-2248.
-
(2012)
Neurochem. Res.
, vol.37
, pp. 2235-2248
-
-
Wang, J.1
Hou, J.2
Zhang, P.3
Li, D.4
Zhang, C.5
Liu, J.6
-
118
-
-
84862804390
-
Tong Luo Jiu Nao injection, a traditional Chinese medicinal preparation, inhibits MIP-1 expression in brain microvascular endothelial cells injured by oxygen-glucose deprivation
-
Wang, J., Li, P.T., Du, H., Hou, J.C., Li, W.H., Pan, Y.S., and Chen, H.C. (2012b). Tong Luo Jiu Nao injection, a traditional Chinese medicinal preparation, inhibits MIP-1 expression in brain microvascular endothelial cells injured by oxygen-glucose deprivation. J. Ethnopharmacol. 141, 151-157.
-
(2012)
J. Ethnopharmacol.
, vol.141
, pp. 151-157
-
-
Wang, J.1
Li, P.T.2
Du, H.3
Hou, J.C.4
Li, W.H.5
Pan, Y.S.6
Chen, H.C.7
-
119
-
-
84896900637
-
Pharmacokinetics, bioavailability and tissue distribution of geniposide following intravenous and peroral administration to rats
-
Wang, F., Cao, J., Hao, J., and Liu, K. (2014). Pharmacokinetics, bioavailability and tissue distribution of geniposide following intravenous and peroral administration to rats. Biopharm. Drug Dispos. 35, 97-103.
-
(2014)
Biopharm. Drug Dispos.
, vol.35
, pp. 97-103
-
-
Wang, F.1
Cao, J.2
Hao, J.3
Liu, K.4
-
120
-
-
84920792929
-
Pharmacotherapy of Alzheimers disease: Current and future trends
-
Werner, J.G. and Altaf, S.D. (2015). Pharmacotherapy of Alzheimers disease: current and future trends. Expert Rev. Neurother. 15, 3-5.
-
(2015)
Expert Rev. Neurother.
, vol.15
, pp. 3-5
-
-
Werner, J.G.1
Altaf, S.D.2
-
121
-
-
84922267253
-
The development of small molecule angiotensin IV analogs to treat Alzheimers and Parkinsons diseases
-
Wright, J.W., Kawas, L.H., and Harding, J.W. (2014). The development of small molecule angiotensin IV analogs to treat Alzheimers and Parkinsons diseases. Prog. Neurobiol. 125C, 26-46.
-
(2014)
Prog. Neurobiol.
, vol.125 C
, pp. 26-46
-
-
Wright, J.W.1
Kawas, L.H.2
Harding, J.W.3
-
122
-
-
84891959165
-
Microarray and proteomic characterization of molecular mechanism of geniposide in ischemia reperfusion and computer-automated estimation of the possible drug target network
-
Wu, R.G., Qiu, L., Zhang, Y., Zhang, Z.J., Luo, Y.J., and Wang, Y.Y. (2009). Microarray and proteomic characterization of molecular mechanism of geniposide in ischemia reperfusion and computer-automated estimation of the possible drug target network. Neurosci. Res. 65, S122.
-
(2009)
Neurosci. Res.
, vol.65
, pp. S122
-
-
Wu, R.G.1
Qiu, L.2
Zhang, Y.3
Zhang, Z.J.4
Luo, Y.J.5
Wang, Y.Y.6
-
123
-
-
0033973569
-
Genipin, a metabolite derived from the herbal medicine Inchin-ko-to, and suppression of Fas-induced lethal liver apoptosis in mice
-
Yamamoto, M., Miura, N., and Ohtake, N. (2000). Genipin, a metabolite derived from the herbal medicine Inchin-ko-to, and suppression of Fas-induced lethal liver apoptosis in mice. Gastroenterology 118, 380-389.
-
(2000)
Gastroenterology
, vol.118
, pp. 380-389
-
-
Yamamoto, M.1
Miura, N.2
Ohtake, N.3
-
124
-
-
0030014491
-
Neuritogenic effect of natural iridoid compounds on PC12h cells and its possible relation to signaling protein kinases
-
Yamazaki, M., Chiba, K., and Mohri, T. (1996). Neuritogenic effect of natural iridoid compounds on PC12h cells and its possible relation to signaling protein kinases. Biol. Pharm. Bull. 19, 791-795.
-
(1996)
Biol. Pharm. Bull.
, vol.19
, pp. 791-795
-
-
Yamazaki, M.1
Chiba, K.2
Mohri, T.3
-
125
-
-
0034785360
-
Activation of the mitogen-activated protein kinase cascade through nitric oxide synthesis as a mechanism of neuritogenic effect of genipin in PC12h cells
-
Yamazaki, M., Chiba, K., and Mohri, T. (2001a). Activation of the mitogen-activated protein kinase cascade through nitric oxide synthesis as a mechanism of neuritogenic effect of genipin in PC12h cells. J. Neurochem. 79, 45-54.
-
(2001)
J. Neurochem.
, vol.79
, pp. 45-54
-
-
Yamazaki, M.1
Chiba, K.2
Mohri, T.3
-
126
-
-
0035210937
-
Prevention of the neurotoxicity of the amyloid β protein by genipin
-
Yamazaki, M., Sakura, N., and Chiba, K. (2001b). Prevention of the neurotoxicity of the amyloid β protein by genipin. Biol. Pharm. Bull. 24, 1454-1455.
-
(2001)
Biol. Pharm. Bull.
, vol.24
, pp. 1454-1455
-
-
Yamazaki, M.1
Sakura, N.2
Chiba, K.3
-
127
-
-
1642358235
-
Cyclic GMP-dependent neurite outgrowth by genipin and nerve growth factor in PC12h cells
-
Yamazaki, M., Chiba, K., Mohri, T., and Hatanaka, H. (2004). Cyclic GMP-dependent neurite outgrowth by genipin and nerve growth factor in PC12h cells. Eur. J. Pharmacol. 488, 35-43.
-
(2004)
Eur. J. Pharmacol.
, vol.488
, pp. 35-43
-
-
Yamazaki, M.1
Chiba, K.2
Mohri, T.3
Hatanaka, H.4
-
128
-
-
29244475373
-
Differences in neuritogenic response to nitric oxide in PC12 and PC12h cells
-
Yamazaki, M., Chiba, K., and Mohri, T. (2006). Differences in neuritogenic response to nitric oxide in PC12 and PC12h cells. Neurosci. Lett. 393, 222-225.
-
(2006)
Neurosci. Lett.
, vol.393
, pp. 222-225
-
-
Yamazaki, M.1
Chiba, K.2
Mohri, T.3
-
129
-
-
66549103341
-
Genipin suppresses A23187-induced cytotoxicity in neuro2a cells
-
Yamazaki, M., Chiba, K., and Yoshikawa, C. (2009). Genipin suppresses A23187-induced cytotoxicity in neuro2a cells. Biol. Pharm. Bull. 32, 1043-1046.
-
(2009)
Biol. Pharm. Bull.
, vol.32
, pp. 1043-1046
-
-
Yamazaki, M.1
Chiba, K.2
Yoshikawa, C.3
-
130
-
-
70849096115
-
Tempering the wrath of RAGE: An emerging therapeutic strategy against diabetic complications, neurodegeneration, and inflammation
-
Yan, S.F., Du, Yan, S., Ramasamy, R., and Schmidt, A.M. (2009). Tempering the wrath of RAGE: an emerging therapeutic strategy against diabetic complications, neurodegeneration, and inflammation. Ann. Med. 2009, 1-15.
-
(2009)
Ann. Med.
, vol.2009
, pp. 1-15
-
-
Yan, S.F.1
Du Yan, S.2
Ramasamy, R.3
Schmidt, A.M.4
-
131
-
-
84866601293
-
RAGE is a key cellular target for Aβ-induced perturbation in Alzheimers disease
-
Yan, S.S., Chen, D., Yan, S., Guo, L., Du, H., and Chen, J.X. (2012). RAGE is a key cellular target for Aβ-induced perturbation in Alzheimers disease. Front. Biosci. (Schol. Ed.) 4, 240-250.
-
(2012)
Front. Biosci. (Schol. Ed.)
, vol.4
, pp. 240-250
-
-
Yan, S.S.1
Chen, D.2
Yan, S.3
Guo, L.4
Du, H.5
Chen, J.X.6
-
132
-
-
33746998922
-
HPLC method for the determination and pharmacokinetic studies on geniposide in rat serum after oral administration of traditional Chinese medicinal preparation Yin-Zhi-Ku decoction
-
Ye, G., Zhu, H.Y., Zhao, H.L., Xu, B., and Huang, C.G. (2006). HPLC method for the determination and pharmacokinetic studies on geniposide in rat serum after oral administration of traditional Chinese medicinal preparation Yin-Zhi-Ku decoction. Biomed. Chromatogr. 20, 743-747.
-
(2006)
Biomed. Chromatogr.
, vol.20
, pp. 743-747
-
-
Ye, G.1
Zhu, H.Y.2
Zhao, H.L.3
Xu, B.4
Huang, C.G.5
-
133
-
-
78249260599
-
Geniposide induces the expression of heme oxygenase-1 via PI3K/Nrf2- signaling to enhance the antioxidant capacity in primary hippocampal neurons
-
Yin, F., Liu, J., Zheng, X., Guo, L., and Xiao, H. (2010a). Geniposide induces the expression of heme oxygenase-1 via PI3K/Nrf2- signaling to enhance the antioxidant capacity in primary hippocampal neurons. Biol. Pharm. Bull. 33, 1841-1846.
-
(2010)
Biol. Pharm. Bull.
, vol.33
, pp. 1841-1846
-
-
Yin, F.1
Liu, J.2
Zheng, X.3
Guo, L.4
Xiao, H.5
-
134
-
-
77952039825
-
GLP-1 receptor plays a critical role in geniposide-induced expression of heme oxygenase-1 in PC12 cells
-
Yin, F., Liu, J.H., Zheng, X.X., and Guo, L.X. (2010b). GLP-1 receptor plays a critical role in geniposide-induced expression of heme oxygenase-1 in PC12 cells. Acta Pharmacol. Sin. 31, 540-545.
-
(2010)
Acta Pharmacol. Sin.
, vol.31
, pp. 540-545
-
-
Yin, F.1
Liu, J.H.2
Zheng, X.X.3
Guo, L.X.4
-
135
-
-
84874582683
-
Geniposide regulates insulin-degrading enzyme expression to inhibit the cytotoxicity of Aβ1-42 in cortical neurons
-
Yin, F., Zhang, Y., Guo, L., Kong, S., and Liu, J. (2012). Geniposide regulates insulin-degrading enzyme expression to inhibit the cytotoxicity of Aβ1-42 in cortical neurons. CNS Neurol. Disord. Drug Targets 11, 1045-1051.
-
(2012)
CNS Neurol. Disord. Drug Targets
, vol.11
, pp. 1045-1051
-
-
Yin, F.1
Zhang, Y.2
Guo, L.3
Kong, S.4
Liu, J.5
-
136
-
-
69949122535
-
Bioactive iridoid glucosides from the fruit of Gardenia jasminoides
-
Yu, Y., Xie, Z.L., and Gao, H. (2009). Bioactive iridoid glucosides from the fruit of Gardenia jasminoides. J. Nat. Prod. 72, 1459-1464.
-
(2009)
J. Nat. Prod.
, vol.72
, pp. 1459-1464
-
-
Yu, Y.1
Xie, Z.L.2
Gao, H.3
-
137
-
-
84873904635
-
Effect of borneol on the pharmacokinetics of geniposide in cortex, hippocampus, hypothalamus and striatum of conscious rat by simultaneous microdialysis coupled with UPLC-MS
-
Yu, B., Ruan, M., Cui, X.B., Guo, J.M., Xu, L., and Dong, X.P. (2013). Effect of borneol on the pharmacokinetics of geniposide in cortex, hippocampus, hypothalamus and striatum of conscious rat by simultaneous microdialysis coupled with UPLC-MS. J. Pharm. Biomed. Anal. 77, 128-132.
-
(2013)
J. Pharm. Biomed. Anal.
, vol.77
, pp. 128-132
-
-
Yu, B.1
Ruan, M.2
Cui, X.B.3
Guo, J.M.4
Xu, L.5
Dong, X.P.6
-
138
-
-
77957221994
-
Identification of a new anti-LPS agent, geniposide from Gardenia jasminoides Ellis, and its ability of direct binding and neutralization of lipopolysaccharide in vitro and in vivo
-
Zheng, X., Yang, D., Liu, X., Wang, N., Li, B., Cao, H., Lu, Y., Wei, G., Zhou, H., and Zheng, J. (2010). Identification of a new anti-LPS agent, geniposide from Gardenia jasminoides Ellis, and its ability of direct binding and neutralization of lipopolysaccharide in vitro and in vivo. Int. Immunopharmacol. 10, 1209-1219.
-
(2010)
Int. Immunopharmacol.
, vol.10
, pp. 1209-1219
-
-
Zheng, X.1
Yang, D.2
Liu, X.3
Wang, N.4
Li, B.5
Cao, H.6
Lu, Y.7
Wei, G.8
Zhou, H.9
Zheng, J.10
-
139
-
-
33646974335
-
Effect of geniposide on serum IL-1β and TNF-α of rheumatoid arthritis rats
-
Zhu, J., Gao, X., Xie, W.L., Jin, Y.Z., and Sun, W.J. (2005). Effect of geniposide on serum IL-1β and TNF-α of rheumatoid arthritis rats. China J. Chin. Mat. Med. 30, 708-711.
-
(2005)
China J. Chin. Mat. Med.
, vol.30
, pp. 708-711
-
-
Zhu, J.1
Gao, X.2
Xie, W.L.3
Jin, Y.Z.4
Sun, W.J.5
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