Treadmill exercise represses neuronal cell death and inflammation during Aβ-induced ER stress by regulating unfolded protein response in aged presenilin 2 mutant mice

Apoptosis

Volumn 18, Issue 11, 2013, Pages 1332-1347

  Kang, Eun Bum ^a   Kwon, In Su ^a   Koo, Jung Hoon ^a   Kim, Eung Joon ^d   Kim, Chul Hyun ^a   Lee, Jin ^b   Yang, Choon Ho ^e   Lee, Young Il ^c   Cho, In Ho ^a   Cho, Joon Yong ^a  

^a Korea National Sport University   (South Korea)

^b Hanyang University   (South Korea)

^c UNIVERSITY OF WEST FLORIDA   (United States)

^d Kyonggi University   (South Korea)

^e Department of Aviation and Marine Sports   (South Korea)

Author keywords

Alzheimer's disease; Endoplasmic reticulum stress; Neuroinflammation; Neuronal cell death; Treadmill exercise; Unfolded protein response

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; AMYLOID BETA PROTEIN; BETA SECRETASE 1; CASPASE 12; CASPASE 3; GLUCOSE REGULATED PROTEIN 78; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; INTERLEUKIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE P38; PRESENILIN 2; PROTEIN BAX; PROTEIN BCL 2; PROTEIN C 99; PROTEIN DISULFIDE ISOMERASE; PROTEIN KINASE; PROTEIN PERK; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HIPPOCAMPUS; INFLAMMATION; MEMORY DISORDER; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FOLDING; TRANSGENIC MOUSE; TREADMILL EXERCISE; UNFOLDED PROTEIN RESPONSE;

MUS;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; CASPASES; CEREBRAL CORTEX; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HIPPOCAMPUS; HUMANS; INFLAMMATION; MICE; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; PEPTIDE FRAGMENTS; PHYSICAL CONDITIONING, ANIMAL; PRESENILIN-2; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EID: 84886388885     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-013-0884-9     Document Type: Article

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