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Volumn 125, Issue , 2015, Pages 26-46

The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases

Author keywords

Alzheimer's disease; Angiotensin IV; AT4 receptor subtype; C Met receptor; Dihexa; Hepatocyte growth factor; Parkinson's disease

Indexed keywords

AMINOPEPTIDASE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN 4 RECEPTOR; ANGIOTENSIN II [3-8]; ANGIOTENSIN RECEPTOR; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; CHOLINESTERASE INHIBITOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; INSULIN REGULATED AMINOPEPTIDASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RECEPTOR SUBTYPE; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG; ANGIOTENSIN II; ANGIOTENSIN II, DES-ASP(1)-DES-ARG(2)-ILE(5)-; AT4 RECEPTOR;

EID: 84922267253     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2014.11.004     Document Type: Review
Times cited : (36)

References (386)
  • 1
    • 27644543354 scopus 로고    scopus 로고
    • Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis
    • Abounader R., Laterra J. Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis. Neuro Oncol. 2005, 7:436-451.
    • (2005) Neuro Oncol. , vol.7 , pp. 436-451
    • Abounader, R.1    Laterra, J.2
  • 2
    • 77950365879 scopus 로고    scopus 로고
    • Accelerated adhesion of grafted skin by laser-induced stress wave-based gene transfer of hepatocyte growth factor
    • Aizawa K., Sato S., Terakawa M., Saitoh D., Tsuda H., Ashida H., Obara M. Accelerated adhesion of grafted skin by laser-induced stress wave-based gene transfer of hepatocyte growth factor. J. Biomed. Opt. 2009, 14:064043.
    • (2009) J. Biomed. Opt. , vol.14 , pp. 064043
    • Aizawa, K.1    Sato, S.2    Terakawa, M.3    Saitoh, D.4    Tsuda, H.5    Ashida, H.6    Obara, M.7
  • 5
    • 74649085115 scopus 로고    scopus 로고
    • Gene knock-out of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age related deficit in spatial memory
    • Albiston A.L., Fernando R.N., Yeatman H.R., Burns P., Ng I., Daswani D., Diwakarla S., Pham V., Chai S.Y. Gene knock-out of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age related deficit in spatial memory. Neurobiol. Learn. Mem. 2010, 93:19-30.
    • (2010) Neurobiol. Learn. Mem. , vol.93 , pp. 19-30
    • Albiston, A.L.1    Fernando, R.N.2    Yeatman, H.R.3    Burns, P.4    Ng, I.5    Daswani, D.6    Diwakarla, S.7    Pham, V.8    Chai, S.Y.9
  • 13
    • 0036814122 scopus 로고    scopus 로고
    • The cholinergic approach for the treatment of vascular dementia: evidence from pre-clinical and clinical studies
    • Amenta F., Di Tullio M.A., Tomassoni D. The cholinergic approach for the treatment of vascular dementia: evidence from pre-clinical and clinical studies. Clin. Exp. Hypertens. 2002, 24:697-713.
    • (2002) Clin. Exp. Hypertens. , vol.24 , pp. 697-713
    • Amenta, F.1    Di Tullio, M.A.2    Tomassoni, D.3
  • 15
    • 47349126657 scopus 로고    scopus 로고
    • Ligands to the (IRAP)/AT4 receptor encompassing a 4-hydroxydiphenylmethane scaffold replacing Tyr2
    • Andersson H., Demaegdt H., Vauquelin G., Lindeberg G., Karlen A., Hallberg M. Ligands to the (IRAP)/AT4 receptor encompassing a 4-hydroxydiphenylmethane scaffold replacing Tyr2. Bioorg. Med. Chem. 2008, 16:6924-6935.
    • (2008) Bioorg. Med. Chem. , vol.16 , pp. 6924-6935
    • Andersson, H.1    Demaegdt, H.2    Vauquelin, G.3    Lindeberg, G.4    Karlen, A.5    Hallberg, M.6
  • 16
    • 78649500321 scopus 로고    scopus 로고
    • Disulfide cyclized tripeptide analogues of angiotensin IV as potent and selective inhibitors of insulin-regulated aminopeptidase (IRAP)
    • Andersson H., Demaegdt H., Vauquelin G., Lindeberg G., Karten A., Hallberg M., Erdelyl M., Hallberg A. Disulfide cyclized tripeptide analogues of angiotensin IV as potent and selective inhibitors of insulin-regulated aminopeptidase (IRAP). J. Med. Chem. 2010, 53:8059-8071.
    • (2010) J. Med. Chem. , vol.53 , pp. 8059-8071
    • Andersson, H.1    Demaegdt, H.2    Vauquelin, G.3    Lindeberg, G.4    Karten, A.5    Hallberg, M.6    Erdelyl, M.7    Hallberg, A.8
  • 17
    • 84871843262 scopus 로고    scopus 로고
    • Discovery of inhibitors of insulin-regulated aminopeptidase as cognitive enhancers
    • ID 789671
    • Andersson H., Hallberg M. Discovery of inhibitors of insulin-regulated aminopeptidase as cognitive enhancers. Int. J. Hypertens. 2012, 12. ID 789671.
    • (2012) Int. J. Hypertens. , pp. 12
    • Andersson, H.1    Hallberg, M.2
  • 18
    • 62149122986 scopus 로고    scopus 로고
    • Use of antihypertensives and the risk of Parkinson disease
    • Ascherio A., Tanner C.M. Use of antihypertensives and the risk of Parkinson disease. Neurology 2009, 72:578-579.
    • (2009) Neurology , vol.72 , pp. 578-579
    • Ascherio, A.1    Tanner, C.M.2
  • 19
    • 84884271395 scopus 로고    scopus 로고
    • Current status of renin-aldosterone angiotensin system-targeting anti-hypertensive drugs as therapeutic options for Alzheimer's disease
    • Ashby E.L., Kehoe P.G. Current status of renin-aldosterone angiotensin system-targeting anti-hypertensive drugs as therapeutic options for Alzheimer's disease. Expert Open. Invest. Drugs 2013, 22:1229-1242.
    • (2013) Expert Open. Invest. Drugs , vol.22 , pp. 1229-1242
    • Ashby, E.L.1    Kehoe, P.G.2
  • 22
    • 51049117095 scopus 로고    scopus 로고
    • A high affinity hepatocyte growth factor-binding site in the immunoglobulin-like region of Met
    • Basillico C., Amesano A., Galluzzo M., Comoglio P.M., Michieli P. A high affinity hepatocyte growth factor-binding site in the immunoglobulin-like region of Met. J. Biol. Chem. 2008, 283:21267-21277.
    • (2008) J. Biol. Chem. , vol.283 , pp. 21267-21277
    • Basillico, C.1    Amesano, A.2    Galluzzo, M.3    Comoglio, P.M.4    Michieli, P.5
  • 23
    • 17444370940 scopus 로고    scopus 로고
    • Protective effect of the inhibition of the renin-angiotensin system on aging
    • Basso N., Paglia N., Stella I. Protective effect of the inhibition of the renin-angiotensin system on aging. Regul. Pept. 2005, 128:247-252.
    • (2005) Regul. Pept. , vol.128 , pp. 247-252
    • Basso, N.1    Paglia, N.2    Stella, I.3
  • 24
    • 0025309926 scopus 로고
    • Angiotensin converting enzyme inhibitors
    • Bauer J.H. Angiotensin converting enzyme inhibitors. Am. J. Hypertens. 1990, 3:331-337.
    • (1990) Am. J. Hypertens. , vol.3 , pp. 331-337
    • Bauer, J.H.1
  • 26
    • 42049114453 scopus 로고    scopus 로고
    • Use of antihypertensives and the risk of Parkinson disease
    • Becker C., Jick S.S., Meier C.R. Use of antihypertensives and the risk of Parkinson disease. Neurology 2008, 70(6):438-444.
    • (2008) Neurology , vol.70 , Issue.6 , pp. 438-444
    • Becker, C.1    Jick, S.S.2    Meier, C.R.3
  • 27
    • 0017192832 scopus 로고
    • Angiotensin II binding to mammalian brain membranes
    • Bennett J.P., Snyder S.H. Angiotensin II binding to mammalian brain membranes. J. Biol. Chem. 1976, 251:7423-7430.
    • (1976) J. Biol. Chem. , vol.251 , pp. 7423-7430
    • Bennett, J.P.1    Snyder, S.H.2
  • 31
    • 0027944723 scopus 로고
    • A specific binding site recognizing a fragment of angiotensin II in bovine adrenal cortex membranes
    • Bernier S.G., Fournier A., Guillemette G. A specific binding site recognizing a fragment of angiotensin II in bovine adrenal cortex membranes. Eur. J. Pharmacol. 1994, 271:55-63.
    • (1994) Eur. J. Pharmacol. , vol.271 , pp. 55-63
    • Bernier, S.G.1    Fournier, A.2    Guillemette, G.3
  • 32
    • 84872410904 scopus 로고    scopus 로고
    • Inhibition of central angiotensin II enhances memory function and reduces oxidative stress status in rat hippocampus
    • Bild W., Hritcu L., Stefanescu C., Ciobica A. Inhibition of central angiotensin II enhances memory function and reduces oxidative stress status in rat hippocampus. Prog. Neuropsychopharmacol. Biol. Psychiatry 2013, 43:79-88.
    • (2013) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.43 , pp. 79-88
    • Bild, W.1    Hritcu, L.2    Stefanescu, C.3    Ciobica, A.4
  • 34
    • 0032189977 scopus 로고    scopus 로고
    • Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase
    • Birchmeier C., Gherardi E. Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase. Trends Cell Biol. 1998, 8:404-410.
    • (1998) Trends Cell Biol. , vol.8 , pp. 404-410
    • Birchmeier, C.1    Gherardi, E.2
  • 37
    • 33646933538 scopus 로고    scopus 로고
    • 2 dopamine receptor blockade prevents cognitive effects of AngIV and des-Phe6 AngIV
    • 2 dopamine receptor blockade prevents cognitive effects of AngIV and des-Phe6 AngIV. Physiol. Behav. 2006, 88:152-159.
    • (2006) Physiol. Behav. , vol.88 , pp. 152-159
    • Braszko, J.J.1
  • 38
    • 0024202954 scopus 로고
    • Angiotensin II (3-8)-hexapeptide affects motor activity, performance of passive avoidance, and a conditioned avoidance response in rats
    • Braszko J.J., Kupryszewski G., Witczuk B., Wisniewski K. Angiotensin II (3-8)-hexapeptide affects motor activity, performance of passive avoidance, and a conditioned avoidance response in rats. Neuroscience 1988, 27:777-783.
    • (1988) Neuroscience , vol.27 , pp. 777-783
    • Braszko, J.J.1    Kupryszewski, G.2    Witczuk, B.3    Wisniewski, K.4
  • 39
    • 33751008654 scopus 로고    scopus 로고
    • Cognitive effects attributed to angiotensin II may result from its conversion to angiotensin IV
    • Braszko J.J., Walesiuk A., Wielgat P. Cognitive effects attributed to angiotensin II may result from its conversion to angiotensin IV. J. Renin Angiotensin Aldosterone Syst. 2006, 7:168-174.
    • (2006) J. Renin Angiotensin Aldosterone Syst. , vol.7 , pp. 168-174
    • Braszko, J.J.1    Walesiuk, A.2    Wielgat, P.3
  • 40
    • 44649113091 scopus 로고    scopus 로고
    • Effect of D(3) dopamine receptor blockade on the cognitive effects of angiotensin IV in rats
    • Braszko J.J., Wielgat P., Walesiuk A. Effect of D(3) dopamine receptor blockade on the cognitive effects of angiotensin IV in rats. Neuropeptides 2008, 42:301-309.
    • (2008) Neuropeptides , vol.42 , pp. 301-309
    • Braszko, J.J.1    Wielgat, P.2    Walesiuk, A.3
  • 41
    • 0026081809 scopus 로고
    • The 3-7 fragment of angiotensin II is probably responsible for its psychoactive properties
    • Braszko J.J., Wlasienko J., Koziolkiewicz W., Janecka A., Wisniewski K. The 3-7 fragment of angiotensin II is probably responsible for its psychoactive properties. Brain Res. 1991, 542:49-54.
    • (1991) Brain Res. , vol.542 , pp. 49-54
    • Braszko, J.J.1    Wlasienko, J.2    Koziolkiewicz, W.3    Janecka, A.4    Wisniewski, K.5
  • 43
    • 0009566277 scopus 로고    scopus 로고
    • Pathological correlates of late onset dementia in a multicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)
    • Brayne C., Matthews F.E., Xuereb J.H. Pathological correlates of late onset dementia in a multicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Lancet 2001, 357:169-175.
    • (2001) Lancet , vol.357 , pp. 169-175
    • Brayne, C.1    Matthews, F.E.2    Xuereb, J.H.3
  • 44
    • 84896718561 scopus 로고    scopus 로고
    • Current therapeutic advances in patients and experimental models of Huntington's disease
    • Brett A.C., Rosenstock T.R., Rego A.C. Current therapeutic advances in patients and experimental models of Huntington's disease. Curr. Drug Targets 2014, 15:313-334.
    • (2014) Curr. Drug Targets , vol.15 , pp. 313-334
    • Brett, A.C.1    Rosenstock, T.R.2    Rego, A.C.3
  • 45
    • 0015840363 scopus 로고
    • Angiotensin II blockade in man by SAR ALA angiotensin II for understanding and treatment of high blood pressure
    • Brunner H.R., Gavras H., Laragh J.H., Keenan R. Angiotensin II blockade in man by SAR ALA angiotensin II for understanding and treatment of high blood pressure. Lancet 1973, 2:1045-1048.
    • (1973) Lancet , vol.2 , pp. 1045-1048
    • Brunner, H.R.1    Gavras, H.2    Laragh, J.H.3    Keenan, R.4
  • 46
    • 71649108692 scopus 로고    scopus 로고
    • Emerging cognitive enhancing drugs
    • Buccafusco J.J. Emerging cognitive enhancing drugs. Expert Open. Emerg. Drugs 2009, 14:577-589.
    • (2009) Expert Open. Emerg. Drugs , vol.14 , pp. 577-589
    • Buccafusco, J.J.1
  • 47
    • 0018100912 scopus 로고
    • Angiotensin-induced thirst: effects of third ventricle obstruction and periventricular ablation
    • Buggy J., Johnson A.K. Angiotensin-induced thirst: effects of third ventricle obstruction and periventricular ablation. Brain Res. 1978, 149:117-128.
    • (1978) Brain Res. , vol.149 , pp. 117-128
    • Buggy, J.1    Johnson, A.K.2
  • 48
    • 12444316765 scopus 로고
    • Synthesis and pharmacology of the octapeptide angiotonin
    • Bumpus F.M., Schwarz H., Page I.H. Synthesis and pharmacology of the octapeptide angiotonin. Science 1957, 125:886-887.
    • (1957) Science , vol.125 , pp. 886-887
    • Bumpus, F.M.1    Schwarz, H.2    Page, I.H.3
  • 49
    • 16044364736 scopus 로고
    • Synthesis and properties of angiotonin
    • Bumpus F.M., Schwarz H., Page I.H. Synthesis and properties of angiotonin. Circulation 1958, 17:664-667.
    • (1958) Circulation , vol.17 , pp. 664-667
    • Bumpus, F.M.1    Schwarz, H.2    Page, I.H.3
  • 52
    • 0023144129 scopus 로고
    • Effects of nigral dopaminergic lesions and striatal excitotoxin lesions on brain converting enzyme
    • Chai S.Y., Christie M.J., Beart P.M., Mendelsohn F.A. Effects of nigral dopaminergic lesions and striatal excitotoxin lesions on brain converting enzyme. Neurochem. Int. 1987, 10:101-107.
    • (1987) Neurochem. Int. , vol.10 , pp. 101-107
    • Chai, S.Y.1    Christie, M.J.2    Beart, P.M.3    Mendelsohn, F.A.4
  • 53
    • 0025139839 scopus 로고
    • Angiotensin converting enzyme in the human basal forebrain and midbrain visualized by in vitro autoradiography
    • Chai S.Y., McKenzie J.S., McKinley M.J., Mendelsohn F.A. Angiotensin converting enzyme in the human basal forebrain and midbrain visualized by in vitro autoradiography. J. Comp. Neurol. 1990, 291:179-194.
    • (1990) J. Comp. Neurol. , vol.291 , pp. 179-194
    • Chai, S.Y.1    McKenzie, J.S.2    McKinley, M.J.3    Mendelsohn, F.A.4
  • 57
    • 64349083816 scopus 로고    scopus 로고
    • The non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment
    • Chaudhuri K.R., Shapira A.H. The non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment. Lancet Neurol. 2009, 8:464-474.
    • (2009) Lancet Neurol. , vol.8 , pp. 464-474
    • Chaudhuri, K.R.1    Shapira, A.H.2
  • 59
    • 79955648520 scopus 로고    scopus 로고
    • Scientific truth or false hope: understanding Alzheimer's disease from an aging perspective
    • Chen M., Maleski J.J., Sawmiller D.R. Scientific truth or false hope: understanding Alzheimer's disease from an aging perspective. J. Alzheimers Dis. 2011, 24:3-10.
    • (2011) J. Alzheimers Dis. , vol.24 , pp. 3-10
    • Chen, M.1    Maleski, J.J.2    Sawmiller, D.R.3
  • 60
    • 0032957467 scopus 로고    scopus 로고
    • Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding
    • Chirgadze D.Y., Heppie J.P., Zhou H., Byrd R.A., Blundell T.L., Gherardi E. Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding. Nat. Struct. Biol. 1999, 6:72-79.
    • (1999) Nat. Struct. Biol. , vol.6 , pp. 72-79
    • Chirgadze, D.Y.1    Heppie, J.P.2    Zhou, H.3    Byrd, R.A.4    Blundell, T.L.5    Gherardi, E.6
  • 61
    • 33746014948 scopus 로고    scopus 로고
    • Changing the course of Alzheimer's disease: emerging modifying therapies
    • Christensen D.D. Changing the course of Alzheimer's disease: emerging modifying therapies. Curr. Psychiatry Rev. 2006, 2:179-188.
    • (2006) Curr. Psychiatry Rev. , vol.2 , pp. 179-188
    • Christensen, D.D.1
  • 62
    • 0002093566 scopus 로고    scopus 로고
    • Clinical manifestations and diagnostic evalulation of patients with Alzheimer's disease
    • McGraw-Hill, New York, NY, C.M. Clark, J.Q. Trajanowski (Eds.)
    • Clark C.M. Clinical manifestations and diagnostic evalulation of patients with Alzheimer's disease. Neurodegenerative Dementias: Clinical Features and Pathological Mechanisms 2000, 95-114. McGraw-Hill, New York, NY. C.M. Clark, J.Q. Trajanowski (Eds.).
    • (2000) Neurodegenerative Dementias: Clinical Features and Pathological Mechanisms , pp. 95-114
    • Clark, C.M.1
  • 63
    • 33947211176 scopus 로고    scopus 로고
    • Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to Parkinsonism
    • Collier T.J., Kipton J., Daley F., Palfi S., Chu Y., Sortwell C., Collier T.J., Carvey P.M. Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to Parkinsonism. Neurobiol. Dis. 2007, 26:56-65.
    • (2007) Neurobiol. Dis. , vol.26 , pp. 56-65
    • Collier, T.J.1    Kipton, J.2    Daley, F.3    Palfi, S.4    Chu, Y.5    Sortwell, C.6    Collier, T.J.7    Carvey, P.M.8
  • 64
    • 0023255371 scopus 로고
    • Motor performance in rats exposed to severe forebrain ischemia: effect of fasting and 1,3-butanediol
    • Combs D., D'Alecy I. Motor performance in rats exposed to severe forebrain ischemia: effect of fasting and 1,3-butanediol. Stroke 1987, 18:503-511.
    • (1987) Stroke , vol.18 , pp. 503-511
    • Combs, D.1    D'Alecy, I.2
  • 65
    • 33644887722 scopus 로고    scopus 로고
    • The molecular and clinical impact of hepatocyte growth factor, its receptor, activators, and inhibitors in wound healing
    • Conway K., Price P., Harding K.G., Jiang W.G. The molecular and clinical impact of hepatocyte growth factor, its receptor, activators, and inhibitors in wound healing. Wound Repair Regen. 2006, 14:2-10.
    • (2006) Wound Repair Regen. , vol.14 , pp. 2-10
    • Conway, K.1    Price, P.2    Harding, K.G.3    Jiang, W.G.4
  • 66
    • 34848879002 scopus 로고    scopus 로고
    • Hepatocyte growth factor regulation: an integral part of why wounds become chronic
    • Conway K., Ruge F., Price P., Harding K.G., Jiang W.G. Hepatocyte growth factor regulation: an integral part of why wounds become chronic. Wound Repair Regen. 2007, 15:683-692.
    • (2007) Wound Repair Regen. , vol.15 , pp. 683-692
    • Conway, K.1    Ruge, F.2    Price, P.3    Harding, K.G.4    Jiang, W.G.5
  • 67
    • 84903770556 scopus 로고    scopus 로고
    • The many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapy
    • 2014 Epub ahead of print
    • Cortes C.J., La Spada A.R., 2014 The many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapy. Drug Discov. Today 2014, Epub ahead of print.
    • (2014) Drug Discov. Today
    • Cortes, C.J.1    La Spada, A.R.2
  • 70
    • 79956125839 scopus 로고    scopus 로고
    • Biomarkers in Alzheimer's disease drug development
    • Cummings J.L. Biomarkers in Alzheimer's disease drug development. Alzheimers Dement. 2011, 7:e13-e44.
    • (2011) Alzheimers Dement. , vol.7 , pp. e13-e44
    • Cummings, J.L.1
  • 71
    • 0038711652 scopus 로고    scopus 로고
    • Hepatocyte growth factor preserves beta cell mass and mitigates hyperglycemia in streptozotocin-induced diabetic mice
    • Dai C., Li Y., Hang J., Liu Y. Hepatocyte growth factor preserves beta cell mass and mitigates hyperglycemia in streptozotocin-induced diabetic mice. J. Biol. Chem. 2003, 278:27080-27087.
    • (2003) J. Biol. Chem. , vol.278 , pp. 27080-27087
    • Dai, C.1    Li, Y.2    Hang, J.3    Liu, Y.4
  • 72
    • 25144464664 scopus 로고    scopus 로고
    • Beta-cell-specific ablation of the hepatocyte growth factor receptor results in reduced islet size, impaired insulin secretion, and glucose intolerance
    • Dai C., Huh C.G., Thorgeirsson S.S., Liu Y. Beta-cell-specific ablation of the hepatocyte growth factor receptor results in reduced islet size, impaired insulin secretion, and glucose intolerance. Am. J. Pathol. 2005, 167:429l-436l.
    • (2005) Am. J. Pathol. , vol.167 , pp. 429l-436l
    • Dai, C.1    Huh, C.G.2    Thorgeirsson, S.S.3    Liu, Y.4
  • 74
    • 78651363548 scopus 로고    scopus 로고
    • Angiotensin II receptors and drug discovery in cardiovascular disease
    • Dasgupta C., Zhang L. Angiotensin II receptors and drug discovery in cardiovascular disease. Drug Discov. Today 2011, 16:22-34.
    • (2011) Drug Discov. Today , vol.16 , pp. 22-34
    • Dasgupta, C.1    Zhang, L.2
  • 76
    • 8444246829 scopus 로고    scopus 로고
    • Hepatocyte growth factor improved learning and memory dysfunction of microsphere-embolized rats
    • Date I., Takagi N., Takagi K., Kago T., Matsumoto K., Nakamura T., Takeo S. Hepatocyte growth factor improved learning and memory dysfunction of microsphere-embolized rats. J. Neurosci. Res. 2004, 78:442-543.
    • (2004) J. Neurosci. Res. , vol.78 , pp. 442-543
    • Date, I.1    Takagi, N.2    Takagi, K.3    Kago, T.4    Matsumoto, K.5    Nakamura, T.6    Takeo, S.7
  • 77
    • 31144450690 scopus 로고    scopus 로고
    • AT4 receptor activation increases intracellular calcium influx and induces a non-N-methyl-d-aspartate dependent form of long-term potentiation
    • Davis C.J., Kramár E.A., De A., Meighan P.D., Simasko S.M., Wright J.W., Harding J.W. AT4 receptor activation increases intracellular calcium influx and induces a non-N-methyl-d-aspartate dependent form of long-term potentiation. Neuroscience 2006, 137:1369-1379.
    • (2006) Neuroscience , vol.137 , pp. 1369-1379
    • Davis, C.J.1    Kramár, E.A.2    De, A.3    Meighan, P.D.4    Simasko, S.M.5    Wright, J.W.6    Harding, J.W.7
  • 79
    • 56049111427 scopus 로고    scopus 로고
    • AngII and AngIV: unraveling the mechanism of action on synaptic plasticity, memory, and epilepsy
    • De Bundel D., Smolders I., Vanderheyden P., Michotte Y. AngII and AngIV: unraveling the mechanism of action on synaptic plasticity, memory, and epilepsy. CNS Neurosci. Ther. 2008, 14:315-339.
    • (2008) CNS Neurosci. Ther. , vol.14 , pp. 315-339
    • De Bundel, D.1    Smolders, I.2    Vanderheyden, P.3    Michotte, Y.4
  • 80
    • 67349263442 scopus 로고    scopus 로고
    • Angiotensin IV and LVV-haemorphin 7 enhance spatial working memory in rats: effects on hippocampal glucose levels and blood flow
    • De Bundel D., Smolders I., Yang R., Albiston A.L., Michotte Y., Chai S.Y. Angiotensin IV and LVV-haemorphin 7 enhance spatial working memory in rats: effects on hippocampal glucose levels and blood flow. Neurobiol. Learn. Mem. 2009, 92:19-26.
    • (2009) Neurobiol. Learn. Mem. , vol.92 , pp. 19-26
    • De Bundel, D.1    Smolders, I.2    Yang, R.3    Albiston, A.L.4    Michotte, Y.5    Chai, S.Y.6
  • 83
    • 0033824138 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXIII. The angiotensin II receptors
    • de Gasparo M., Catt K.J., Inagami T., Wright J.W., Unger T. International Union of Pharmacology. XXIII. The angiotensin II receptors. Pharmacol. Rev. 2000, 52:415-472.
    • (2000) Pharmacol. Rev. , vol.52 , pp. 415-472
    • de Gasparo, M.1    Catt, K.J.2    Inagami, T.3    Wright, J.W.4    Unger, T.5
  • 88
    • 84883707873 scopus 로고    scopus 로고
    • Executive dysfunction in Parkinson's disease; a review
    • Dirnberger G., Jahanshahi M. Executive dysfunction in Parkinson's disease; a review. J. Neuropsychol. 2013, 7:193-224.
    • (2013) J. Neuropsychol. , vol.7 , pp. 193-224
    • Dirnberger, G.1    Jahanshahi, M.2
  • 89
    • 33644652951 scopus 로고    scopus 로고
    • Proteasome regulation of oxidative stress in aging and age-related disease of the CNS
    • Ding Q., Dimayuga E., Keller J.N. Proteasome regulation of oxidative stress in aging and age-related disease of the CNS. Antioxid. Redox Signal. 2006, 8:163-172.
    • (2006) Antioxid. Redox Signal. , vol.8 , pp. 163-172
    • Ding, Q.1    Dimayuga, E.2    Keller, J.N.3
  • 90
    • 0037834636 scopus 로고    scopus 로고
    • Angiotensin receptors: distribution, signaling and function
    • Dinh D.T., Grauman A.G., Johston C.I., Fabiani M.E. Angiotensin receptors: distribution, signaling and function. Clin. Sci. 2001, 100:481-492.
    • (2001) Clin. Sci. , vol.100 , pp. 481-492
    • Dinh, D.T.1    Grauman, A.G.2    Johston, C.I.3    Fabiani, M.E.4
  • 91
    • 79959678293 scopus 로고    scopus 로고
    • Acute hepatocyte growth factor treatment induces long-term neuroprotection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiation
    • Doeppner T.R., Kaltwasser B., EiAli A., Zechariah A., Hermann D.M., Bahr M. Acute hepatocyte growth factor treatment induces long-term neuroprotection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiation. J. Cereb. Blood Flow Metab. 2011, 31:1251-1262.
    • (2011) J. Cereb. Blood Flow Metab. , vol.31 , pp. 1251-1262
    • Doeppner, T.R.1    Kaltwasser, B.2    EiAli, A.3    Zechariah, A.4    Hermann, D.M.5    Bahr, M.6
  • 93
    • 30344479822 scopus 로고    scopus 로고
    • Pharmacological strategies for the prevention of Alzheimer's disease
    • Doraiswamy P.M., Xiong G.L. Pharmacological strategies for the prevention of Alzheimer's disease. Expert Open. Pharmacother. 2006, 7:1-10.
    • (2006) Expert Open. Pharmacother. , vol.7 , pp. 1-10
    • Doraiswamy, P.M.1    Xiong, G.L.2
  • 94
    • 65249122512 scopus 로고    scopus 로고
    • Novel therapeutic inhibitors of the c-Met signaling pathway in cancer
    • Eder J.P., Vande Woude G.F., Boemer S.A., LoRusso P.M. Novel therapeutic inhibitors of the c-Met signaling pathway in cancer. Clin. Cancer Res. 2009, 15:2207-2214.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 2207-2214
    • Eder, J.P.1    Vande Woude, G.F.2    Boemer, S.A.3    LoRusso, P.M.4
  • 95
    • 0024347759 scopus 로고
    • Angiotensin-converting enzyme: new concepts concerning its biological role
    • Ehlers M.R., Riordan J.F. Angiotensin-converting enzyme: new concepts concerning its biological role. Biochemistry 1989, 28:5311-5318.
    • (1989) Biochemistry , vol.28 , pp. 5311-5318
    • Ehlers, M.R.1    Riordan, J.F.2
  • 96
    • 34250928307 scopus 로고
    • Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system
    • Ehringer H., Horaykieuicz O. Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system. Klin. Wochenschr. 1960, 38:1236-1239.
    • (1960) Klin. Wochenschr. , vol.38 , pp. 1236-1239
    • Ehringer, H.1    Horaykieuicz, O.2
  • 97
    • 78651395471 scopus 로고    scopus 로고
    • Association of candesartan vs losartan with all-cause mortality in patients with heart failure
    • Eklind-Cervenka M., Benson L., Dahlstrom U., Edner M., Rosenqvist M., Lund L.H. Association of candesartan vs losartan with all-cause mortality in patients with heart failure. JAMA 2011, 305:175-182.
    • (2011) JAMA , vol.305 , pp. 175-182
    • Eklind-Cervenka, M.1    Benson, L.2    Dahlstrom, U.3    Edner, M.4    Rosenqvist, M.5    Lund, L.H.6
  • 99
    • 33749648763 scopus 로고    scopus 로고
    • Cerebroprotective effect of angiotensin IV in experimental ischemic stroke in the rat mediated by AT(4) receptors
    • Faure S., Chapot R., Tallet D., Javellaud J., Achard J.M., Oudart N. Cerebroprotective effect of angiotensin IV in experimental ischemic stroke in the rat mediated by AT(4) receptors. J. Physiol. Pharmacol. 2006, 57:329-342.
    • (2006) J. Physiol. Pharmacol. , vol.57 , pp. 329-342
    • Faure, S.1    Chapot, R.2    Tallet, D.3    Javellaud, J.4    Achard, J.M.5    Oudart, N.6
  • 100
    • 47849111875 scopus 로고    scopus 로고
    • The insulin-regulated aminopeptidase IRAP is colocalized with GLUT4 in the mouse hippocampus - potential role in modulation of glucose uptake in neurons?
    • Fernando R.N., Albiston A.L., Chai S.Y. The insulin-regulated aminopeptidase IRAP is colocalized with GLUT4 in the mouse hippocampus - potential role in modulation of glucose uptake in neurons?. Eur. J. Neurosci. 2008, 28:588-598.
    • (2008) Eur. J. Neurosci. , vol.28 , pp. 588-598
    • Fernando, R.N.1    Albiston, A.L.2    Chai, S.Y.3
  • 101
    • 19944397128 scopus 로고    scopus 로고
    • Distribution and cellular localization of insulin-regulated aminopeptidase in the rat central nervous system
    • Fernando R.N., Larm J., Albiston A.L., Chair S.Y. Distribution and cellular localization of insulin-regulated aminopeptidase in the rat central nervous system. J. Comp. Neurol. 2005, 487:372-390.
    • (2005) J. Comp. Neurol. , vol.487 , pp. 372-390
    • Fernando, R.N.1    Larm, J.2    Albiston, A.L.3    Chair, S.Y.4
  • 103
    • 0018815113 scopus 로고
    • Angiotensin stimulation of the central nervous system
    • Fitzsimons J.T. Angiotensin stimulation of the central nervous system. Rev. Physiol. Biochem. Pharmacol. 1980, 87:117-167.
    • (1980) Rev. Physiol. Biochem. Pharmacol. , vol.87 , pp. 117-167
    • Fitzsimons, J.T.1
  • 105
    • 84859438307 scopus 로고    scopus 로고
    • Immunohistochemical localization of the angiotensin-(1-7) receptor Mas in the murine forebrain
    • Freund M., Walther T., von Bohlen und Halbach O. Immunohistochemical localization of the angiotensin-(1-7) receptor Mas in the murine forebrain. Cell Tissue Res. 2012, 348:29-35.
    • (2012) Cell Tissue Res. , vol.348 , pp. 29-35
    • Freund, M.1    Walther, T.2    von Bohlenund Halbach, O.3
  • 106
    • 0037212712 scopus 로고    scopus 로고
    • Hepatocyte growth factor: from diagnosis to clinical applications
    • Funakoshi H., Nakamura T. Hepatocyte growth factor: from diagnosis to clinical applications. Clin. Chim. Acta 2003, 327:1-23.
    • (2003) Clin. Chim. Acta , vol.327 , pp. 1-23
    • Funakoshi, H.1    Nakamura, T.2
  • 107
    • 0025916479 scopus 로고
    • Comparison of biological and immunochemical properties indicates that scatter factor and hepatocyte growth factor are indistinguishable
    • Furlong R.A., Takehara T., Taylor W.G., Nakamura T., Rubin J.S. Comparison of biological and immunochemical properties indicates that scatter factor and hepatocyte growth factor are indistinguishable. J. Cell Sci. 1991, 100:173-177.
    • (1991) J. Cell Sci. , vol.100 , pp. 173-177
    • Furlong, R.A.1    Takehara, T.2    Taylor, W.G.3    Nakamura, T.4    Rubin, J.S.5
  • 108
    • 49349107302 scopus 로고    scopus 로고
    • Renin-angiotensin system revisited
    • Fyhrquist F., Saijonmaa O. Renin-angiotensin system revisited. J. Intern. Med. 2008, 264:224-236.
    • (2008) J. Intern. Med. , vol.264 , pp. 224-236
    • Fyhrquist, F.1    Saijonmaa, O.2
  • 109
    • 79551659343 scopus 로고    scopus 로고
    • Alzheimer's disease: from pathogenesis to disease-modifying approaches
    • Galimberti D., Scarpini E. Alzheimer's disease: from pathogenesis to disease-modifying approaches. CNS Neurol. Disord. Drug Targets 2011, 10:163-174.
    • (2011) CNS Neurol. Disord. Drug Targets , vol.10 , pp. 163-174
    • Galimberti, D.1    Scarpini, E.2
  • 110
    • 0015244611 scopus 로고
    • Renin activity in brain tissue of puppies and adult dogs
    • Ganten D., Boucher R., Genest J. Renin activity in brain tissue of puppies and adult dogs. Brain Res. 1971, 33:557-559.
    • (1971) Brain Res. , vol.33 , pp. 557-559
    • Ganten, D.1    Boucher, R.2    Genest, J.3
  • 112
    • 52649108045 scopus 로고    scopus 로고
    • Efficacy of long-term continuous subcutaneous apomorphine infusion in advanced Parkinson's disease with motor fluctuations: a multicenter study
    • Garcia Ruiz P.J. Efficacy of long-term continuous subcutaneous apomorphine infusion in advanced Parkinson's disease with motor fluctuations: a multicenter study. Mov. Disord. 2008, 23:1130-1136.
    • (2008) Mov. Disord. , vol.23 , pp. 1130-1136
    • Garcia Ruiz, P.J.1
  • 113
    • 0036496910 scopus 로고    scopus 로고
    • The role of angiotensin II in cognition and behaviour
    • 2002
    • Gard P.R. The role of angiotensin II in cognition and behaviour. Eur. J. Pharmacol. 2002, 438:1-14. 2002.
    • (2002) Eur. J. Pharmacol. , vol.438 , pp. 1-14
    • Gard, P.R.1
  • 114
    • 1242307408 scopus 로고    scopus 로고
    • Angiotensin as a target for the treatment of Alzheimer's disease, anxiety and depression
    • Gard P.R. Angiotensin as a target for the treatment of Alzheimer's disease, anxiety and depression. Expert Open. Ther. Targets 2004, 8:7-14.
    • (2004) Expert Open. Ther. Targets , vol.8 , pp. 7-14
    • Gard, P.R.1
  • 115
    • 57449120247 scopus 로고    scopus 로고
    • Cognitive-enhancing effects of angiotensin IV
    • Gard P.R. Cognitive-enhancing effects of angiotensin IV. BMC Neurosci. 2008, 9(Suppl. 2):S2-S15.
    • (2008) BMC Neurosci. , vol.9 , pp. S2-S15
    • Gard, P.R.1
  • 120
  • 123
    • 0034677947 scopus 로고    scopus 로고
    • NAD(P)H oxidase: role in cardiovascular biology and disease
    • Griendling K.K., Sorescu D., Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ. Res. 2000, 86:494-501.
    • (2000) Circ. Res. , vol.86 , pp. 494-501
    • Griendling, K.K.1    Sorescu, D.2    Ushio-Fukai, M.3
  • 124
    • 4444375163 scopus 로고    scopus 로고
    • HGF regulates the development of cortical pyramidal dendrites
    • Gutierrez H., Dolcet X., Tolcos M., Davies A. HGF regulates the development of cortical pyramidal dendrites. Development 2004, 131:3717-3726.
    • (2004) Development , vol.131 , pp. 3717-3726
    • Gutierrez, H.1    Dolcet, X.2    Tolcos, M.3    Davies, A.4
  • 125
    • 79952778565 scopus 로고    scopus 로고
    • Effects of mesenchymal stem cells transfected with human hepatocyte growth factor gene on healing of burn wounds
    • Ha X.Q., Lv T.D., Hui L., Dong F. Effects of mesenchymal stem cells transfected with human hepatocyte growth factor gene on healing of burn wounds. Chin. J. Traumatol. 2010, 13:349-355.
    • (2010) Chin. J. Traumatol. , vol.13 , pp. 349-355
    • Ha, X.Q.1    Lv, T.D.2    Hui, L.3    Dong, F.4
  • 126
    • 0017141008 scopus 로고
    • The role of renin in normal and pathological cardiovascular homeostasis
    • Haber E. The role of renin in normal and pathological cardiovascular homeostasis. Circulation 1976, 54:849-861.
    • (1976) Circulation , vol.54 , pp. 849-861
    • Haber, E.1
  • 127
    • 31344454633 scopus 로고    scopus 로고
    • Antihypertensive agents for aging patients who are at risk for cognitive dysfunction
    • Hajjar I.M., Keown M., Frost B. Antihypertensive agents for aging patients who are at risk for cognitive dysfunction. Curr. Hypertens. Rep. 2005, 7:466-473.
    • (2005) Curr. Hypertens. Rep. , vol.7 , pp. 466-473
    • Hajjar, I.M.1    Keown, M.2    Frost, B.3
  • 128
    • 42949157265 scopus 로고    scopus 로고
    • Angiotensin converting enzyme inhibitors and cognitive and functional decline in patients with Alzheimer's disease: an observational study
    • Hajjar I.M., Keown M., Lewis P., Almor A. Angiotensin converting enzyme inhibitors and cognitive and functional decline in patients with Alzheimer's disease: an observational study. Am. J. Alzheimers Dis. Other Demen. 2008, 23:77-83.
    • (2008) Am. J. Alzheimers Dis. Other Demen. , vol.23 , pp. 77-83
    • Hajjar, I.M.1    Keown, M.2    Lewis, P.3    Almor, A.4
  • 130
    • 0032811982 scopus 로고    scopus 로고
    • Angiotensin-(1-7) can interact with the rat proximal tubule AT(4) receptor system
    • Handa R.K. Angiotensin-(1-7) can interact with the rat proximal tubule AT(4) receptor system. Am. J. Physiol. 1999, 277:F75-F83.
    • (1999) Am. J. Physiol. , vol.277 , pp. F75-F83
    • Handa, R.K.1
  • 131
    • 34548182310 scopus 로고    scopus 로고
    • Usefulness of ARBs and ACE inhibitors in the prevention of vascular dementia in the elderly
    • Hanes D.S., Weir M.R. Usefulness of ARBs and ACE inhibitors in the prevention of vascular dementia in the elderly. Am. J. Geriatr. Cardiol. 2007, 16:175-182.
    • (2007) Am. J. Geriatr. Cardiol. , vol.16 , pp. 175-182
    • Hanes, D.S.1    Weir, M.R.2
  • 132
    • 0027373353 scopus 로고
    • Elucidation of a specific binding site for angiotensin II(3-8), angiotensin IV, in mammalian heart membranes
    • Hanesworth J.M., Sardinia J.F., Krebs L.T., Hall K.L., Harding J.W. Elucidation of a specific binding site for angiotensin II(3-8), angiotensin IV, in mammalian heart membranes. J. Pharmcol. Exp. Ther. 1993, 266:1036-1042.
    • (1993) J. Pharmcol. Exp. Ther. , vol.266 , pp. 1036-1042
    • Hanesworth, J.M.1    Sardinia, J.F.2    Krebs, L.T.3    Hall, K.L.4    Harding, J.W.5
  • 134
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • Hardy J., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297:353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 136
    • 20444423644 scopus 로고    scopus 로고
    • Angiotensin-(1-7) enhances LTP in the hippocampus through the G protein-coupled receptor Mas
    • Hellner K., Walther T., Schubert M., Albrecht D. Angiotensin-(1-7) enhances LTP in the hippocampus through the G protein-coupled receptor Mas. Mol. Cell. Neurosci. 2005, 29:427-435.
    • (2005) Mol. Cell. Neurosci. , vol.29 , pp. 427-435
    • Hellner, K.1    Walther, T.2    Schubert, M.3    Albrecht, D.4
  • 137
    • 80053971718 scopus 로고    scopus 로고
    • Current and emerging drug treatment options for Alzheimer's disease
    • Herrmann N., Chau S.A., Kircanski I., Lanctót L. Current and emerging drug treatment options for Alzheimer's disease. Drugs 2011, 71:2013-2056.
    • (2011) Drugs , vol.71 , pp. 2013-2056
    • Herrmann, N.1    Chau, S.A.2    Kircanski, I.3    Lanctót, L.4
  • 138
    • 33847152551 scopus 로고    scopus 로고
    • Insights into the structure/function of hepatocyte growth factor/scatter factor from studies with individual domains
    • Holmes O., Pillozzi S., Deakin J.A., Carafoli F., Kemp L., Butler P.J., Lyon M., Gherardi E. Insights into the structure/function of hepatocyte growth factor/scatter factor from studies with individual domains. J. Mol. Biol. 2007, 367:395-408.
    • (2007) J. Mol. Biol. , vol.367 , pp. 395-408
    • Holmes, O.1    Pillozzi, S.2    Deakin, J.A.3    Carafoli, F.4    Kemp, L.5    Butler, P.J.6    Lyon, M.7    Gherardi, E.8
  • 139
    • 84900453992 scopus 로고    scopus 로고
    • Treatment of Alzheimer's disease: current management and experimental therapeutics
    • Honig L.S., Boyd C.D. Treatment of Alzheimer's disease: current management and experimental therapeutics. Curr. Transl. Geniatr. Exp. Gerontol. Rep. 2013, 2:174-181.
    • (2013) Curr. Transl. Geniatr. Exp. Gerontol. Rep. , vol.2 , pp. 174-181
    • Honig, L.S.1    Boyd, C.D.2
  • 140
    • 0036316595 scopus 로고    scopus 로고
    • Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/akt-dependent and MAPK/CREB-independent
    • Hossain M.A., Russell J.C., Gomez R., Laterra J. Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/akt-dependent and MAPK/CREB-independent. J. Neurochem. 2002, 81:365-378.
    • (2002) J. Neurochem. , vol.81 , pp. 365-378
    • Hossain, M.A.1    Russell, J.C.2    Gomez, R.3    Laterra, J.4
  • 142
    • 79959944588 scopus 로고    scopus 로고
    • γ{phonetic}-Secretase inhibitors and modulators for the treatment of Alzheimer's disease: disappointments and hopes
    • Imbimbo B.P., Giardina G.A. γ{phonetic}-Secretase inhibitors and modulators for the treatment of Alzheimer's disease: disappointments and hopes. Curr. Top. Med. Chem. 2011, 11:1555-1570.
    • (2011) Curr. Top. Med. Chem. , vol.11 , pp. 1555-1570
    • Imbimbo, B.P.1    Giardina, G.A.2
  • 143
    • 35848963197 scopus 로고    scopus 로고
    • Intrathecal delivery of hepatocyte growth factor from amyotrophic lateral sclerosis onset suppresses disease progression in rat amyotrophic lateral sclerosis model
    • Ishigaki A., Aoki M., Nagai M., Warita H., Kato S., Kato M. Intrathecal delivery of hepatocyte growth factor from amyotrophic lateral sclerosis onset suppresses disease progression in rat amyotrophic lateral sclerosis model. J. Neuropathol. Exp. Neurol. 2007, 66:1037-1044.
    • (2007) J. Neuropathol. Exp. Neurol. , vol.66 , pp. 1037-1044
    • Ishigaki, A.1    Aoki, M.2    Nagai, M.3    Warita, H.4    Kato, S.5    Kato, M.6
  • 144
    • 84880756245 scopus 로고    scopus 로고
    • Defective autophagy in Parkinson's disease: role of oxidative stress
    • Janda E., Isidoro C., Carresi C., Mollace V. Defective autophagy in Parkinson's disease: role of oxidative stress. Mol. Neurobiol. 2012, 46:639-661.
    • (2012) Mol. Neurobiol. , vol.46 , pp. 639-661
    • Janda, E.1    Isidoro, C.2    Carresi, C.3    Mollace, V.4
  • 146
    • 0031027898 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme modulates dopamine turnover in the striatum
    • Jenkins T.A., Mendelsohn F.A., Chai S.Y. Angiotensin-converting enzyme modulates dopamine turnover in the striatum. J. Neurochem. 1997, 68(3):1304-1311.
    • (1997) J. Neurochem. , vol.68 , Issue.3 , pp. 1304-1311
    • Jenkins, T.A.1    Mendelsohn, F.A.2    Chai, S.Y.3
  • 147
    • 0033038787 scopus 로고    scopus 로고
    • Effect of chronic angiotensin-converting enzyme inhibition on striatal dopamine content in the MPTP-treated mouse
    • Jenkins T.A., Wong J.Y., Howells D.W., Mendelsohn F.A., Chai S.Y. Effect of chronic angiotensin-converting enzyme inhibition on striatal dopamine content in the MPTP-treated mouse. J. Neurochem. 1999, 73:214-219.
    • (1999) J. Neurochem. , vol.73 , pp. 214-219
    • Jenkins, T.A.1    Wong, J.Y.2    Howells, D.W.3    Mendelsohn, F.A.4    Chai, S.Y.5
  • 148
    • 62649089147 scopus 로고    scopus 로고
    • The inflammatory response in the MPTP model of Parkinson's disease is mediated by brain angiotensin: relevance to progression of the disease
    • Joglar B., Rodriguez-Pallares J., Rodriguez-Perez A.I., Rey P., Guerra M.J., Labandeira-Garcia J.L. The inflammatory response in the MPTP model of Parkinson's disease is mediated by brain angiotensin: relevance to progression of the disease. J. Neurochem. 2009, 109:656-669.
    • (2009) J. Neurochem. , vol.109 , pp. 656-669
    • Joglar, B.1    Rodriguez-Pallares, J.2    Rodriguez-Perez, A.I.3    Rey, P.4    Guerra, M.J.5    Labandeira-Garcia, J.L.6
  • 149
    • 0016660889 scopus 로고
    • The cerebral ventricles as the avenue for the dipsogenic action of intracranial angiotensin
    • Johnson A.K., Epstein A.N. The cerebral ventricles as the avenue for the dipsogenic action of intracranial angiotensin. Brain Res. 1975, 86:399-418.
    • (1975) Brain Res. , vol.86 , pp. 399-418
    • Johnson, A.K.1    Epstein, A.N.2
  • 150
    • 0025101253 scopus 로고
    • Biochemistry and pharmacology of the renin-angiotensin system
    • Johnston C.I. Biochemistry and pharmacology of the renin-angiotensin system. Drugs 1990, 39:21-31.
    • (1990) Drugs , vol.39 , pp. 21-31
    • Johnston, C.I.1
  • 152
    • 21544467552 scopus 로고    scopus 로고
    • Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomized clinical trials
    • Kaduszkiewicz H., Zimmermann T., Beck-Bomholdt H.P., van den Bussche H. Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomized clinical trials. BMJ 2005, 331:321-327.
    • (2005) BMJ , vol.331 , pp. 321-327
    • Kaduszkiewicz, H.1    Zimmermann, T.2    Beck-Bomholdt, H.P.3    van den Bussche, H.4
  • 153
    • 0027443482 scopus 로고
    • Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition
    • Kambayashi Y., Bardhan S., Takahashi K., Tsuzuki S., Inui T., Hamakubo T., Inagami Y. Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition. J. Biol. Chem. 1993, 268:24543-24546.
    • (1993) J. Biol. Chem. , vol.268 , pp. 24543-24546
    • Kambayashi, Y.1    Bardhan, S.2    Takahashi, K.3    Tsuzuki, S.4    Inui, T.5    Hamakubo, T.6    Inagami, Y.7
  • 155
    • 84888034614 scopus 로고    scopus 로고
    • A friend in need may not be a friend indeed: role of microglia in neurodegenerative diseases
    • Kaushik D.K., Basu A. A friend in need may not be a friend indeed: role of microglia in neurodegenerative diseases. CNS Neurol. Disord. Drug Targets 2013, 12:726-740.
    • (2013) CNS Neurol. Disord. Drug Targets , vol.12 , pp. 726-740
    • Kaushik, D.K.1    Basu, A.2
  • 156
    • 84875489535 scopus 로고    scopus 로고
    • Nanoscale mapping of the Met receptor on hippocampal neurons by AFM and confocal microscopy
    • Kawas L.H., Benoist C.C., Harding J.W., Wayman G.A., Abu-Lail N.I. Nanoscale mapping of the Met receptor on hippocampal neurons by AFM and confocal microscopy. Nanomedicine 2013, 9:428-438.
    • (2013) Nanomedicine , vol.9 , pp. 428-438
    • Kawas, L.H.1    Benoist, C.C.2    Harding, J.W.3    Wayman, G.A.4    Abu-Lail, N.I.5
  • 158
    • 80054788430 scopus 로고    scopus 로고
    • Mimics of the dimerization domain of hepatocyte growth factor exhibit anti-Met and anticancer activity
    • Kawas L.H., Yamamoto B.J., Wright J.W., Harding J.W. Mimics of the dimerization domain of hepatocyte growth factor exhibit anti-Met and anticancer activity. J. Pharmacol. Exp. Ther. 2011, 339:509-518.
    • (2011) J. Pharmacol. Exp. Ther. , vol.339 , pp. 509-518
    • Kawas, L.H.1    Yamamoto, B.J.2    Wright, J.W.3    Harding, J.W.4
  • 159
    • 33847791727 scopus 로고    scopus 로고
    • Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease?
    • Kehoe P.G., Wilcock G.K. Is inhibition of the renin-angiotensin system a new treatment option for Alzheimer's disease?. Lancet Neurol. 2007, 6:373-378.
    • (2007) Lancet Neurol. , vol.6 , pp. 373-378
    • Kehoe, P.G.1    Wilcock, G.K.2
  • 160
    • 0028802190 scopus 로고
    • Angiotensin induction of PAI-1 expression in endothelial cells is mediated by the hexapeptide angiotensin IV
    • Kerins D.M., Hao Q., Baughan D.E. Angiotensin induction of PAI-1 expression in endothelial cells is mediated by the hexapeptide angiotensin IV. J. Clin. Invest. 1995, 96:2515-2520.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2515-2520
    • Kerins, D.M.1    Hao, Q.2    Baughan, D.E.3
  • 162
  • 163
    • 0025866116 scopus 로고
    • Possible endocrine control by hepatocyte growth factor of liver regeneration after partial hepatectomy
    • Kinoshita T., Hirao S., Matsumoto K., Nakamura T. Possible endocrine control by hepatocyte growth factor of liver regeneration after partial hepatectomy. Biochem. Biophys. Res. Commun. 1991, 17:330-335.
    • (1991) Biochem. Biophys. Res. Commun. , vol.17 , pp. 330-335
    • Kinoshita, T.1    Hirao, S.2    Matsumoto, K.3    Nakamura, T.4
  • 164
    • 77949875945 scopus 로고    scopus 로고
    • Effects of losartan vs candesartan in reducing cardiovascular events in the primary treatment of hypertension
    • Kjeldsen S.E., Stlhammar J., Hasvold P., Bodegard J., Olsson U., Russell D. Effects of losartan vs candesartan in reducing cardiovascular events in the primary treatment of hypertension. J. Hum. Hypertens. 2010, 24:263-273.
    • (2010) J. Hum. Hypertens. , vol.24 , pp. 263-273
    • Kjeldsen, S.E.1    Stlhammar, J.2    Hasvold, P.3    Bodegard, J.4    Olsson, U.5    Russell, D.6
  • 167
    • 33751181265 scopus 로고    scopus 로고
    • Prevention of onset of Parkinson's disease by in vivo gene transfer of human hepatocyte growth factor in rodent model: a model of gene therapy for Parkinson's disease
    • Koike H., Ishida A., Shimamura M., Mizuno S., Nakamura T., Ogihara T. Prevention of onset of Parkinson's disease by in vivo gene transfer of human hepatocyte growth factor in rodent model: a model of gene therapy for Parkinson's disease. Gene Ther. 2006, 13:1639-1644.
    • (2006) Gene Ther. , vol.13 , pp. 1639-1644
    • Koike, H.1    Ishida, A.2    Shimamura, M.3    Mizuno, S.4    Nakamura, T.5    Ogihara, T.6
  • 168
    • 0037387794 scopus 로고    scopus 로고
    • Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene
    • Koike H., Morishita R., Iguchi S., Aoki M., Matsumoto K., Nakamura T. Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene. FASEB J. 2003, 17:779-781.
    • (2003) FASEB J. , vol.17 , pp. 779-781
    • Koike, H.1    Morishita, R.2    Iguchi, S.3    Aoki, M.4    Matsumoto, K.5    Nakamura, T.6
  • 169
    • 0033783263 scopus 로고    scopus 로고
    • Expression of c-Met in developing rat hippocampus: evidence for HGF as a neurotrophic factor for calbindin D-expressing neurons
    • Korhonen L., Sjoholm U., Takei N., Kern M.A., Schirmacher P., Castren E., Lindholm D. Expression of c-Met in developing rat hippocampus: evidence for HGF as a neurotrophic factor for calbindin D-expressing neurons. Eur. J. Neurosci. 2000, 12:3453-3461.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 3453-3461
    • Korhonen, L.1    Sjoholm, U.2    Takei, N.3    Kern, M.A.4    Schirmacher, P.5    Castren, E.6    Lindholm, D.7
  • 170
    • 0035815529 scopus 로고    scopus 로고
    • The effects of angiotensin IV analogs on long-term potentiation within the CA1 region of the hippocampus in vitro
    • Kramár E.A., Armstrong D.L., Ikeda S., Wayner M.J., Harding J.W., Wright J.W. The effects of angiotensin IV analogs on long-term potentiation within the CA1 region of the hippocampus in vitro. Brain Res. 2001, 897:114-121.
    • (2001) Brain Res. , vol.897 , pp. 114-121
    • Kramár, E.A.1    Armstrong, D.L.2    Ikeda, S.3    Wayner, M.J.4    Harding, J.W.5    Wright, J.W.6
  • 171
    • 0031589846 scopus 로고    scopus 로고
    • Angiotensin II- and IV-induced changes in cerebral blood flow. Roles of AT1, AT2, and AT4 receptor subtypes
    • Kramár E.A., Harding J.W., Wright J.W. Angiotensin II- and IV-induced changes in cerebral blood flow. Roles of AT1, AT2, and AT4 receptor subtypes. Regul. Pept. 1997, 68:131-138.
    • (1997) Regul. Pept. , vol.68 , pp. 131-138
    • Kramár, E.A.1    Harding, J.W.2    Wright, J.W.3
  • 172
    • 0031837628 scopus 로고    scopus 로고
    • Role of nitric oxide in angiotensin IV-induced increases in cerebral blood flow
    • Kramár E.A., Krishnan R., Harding J.W., Wright J.W. Role of nitric oxide in angiotensin IV-induced increases in cerebral blood flow. Regul. Pept. 1998, 74:185-192.
    • (1998) Regul. Pept. , vol.74 , pp. 185-192
    • Kramár, E.A.1    Krishnan, R.2    Harding, J.W.3    Wright, J.W.4
  • 173
    • 0030568128 scopus 로고    scopus 로고
    • Characterization of the binding properties and physiological action of divalinal-angiotensin IV, a putative AT4 receptor antagonist
    • Krebs L.T., Kramar E.A., Hanesworth J.M., Sardinia M.F., Ball A.E., Wright J.W., Harding J.W. Characterization of the binding properties and physiological action of divalinal-angiotensin IV, a putative AT4 receptor antagonist. Regul. Pept. 1996, 67:123-130.
    • (1996) Regul. Pept. , vol.67 , pp. 123-130
    • Krebs, L.T.1    Kramar, E.A.2    Hanesworth, J.M.3    Sardinia, M.F.4    Ball, A.E.5    Wright, J.W.6    Harding, J.W.7
  • 177
    • 42349088392 scopus 로고    scopus 로고
    • Hepatocyte growth factor promotes proliferation and migration in immortalized progenitor cells
    • Lan F., Xu J., Zhang X., Wong V.W., Li X., Lu A., Lu W., Shen L., Li L. Hepatocyte growth factor promotes proliferation and migration in immortalized progenitor cells. Neuroreport 2008, 19:765-769.
    • (2008) Neuroreport , vol.19 , pp. 765-769
    • Lan, F.1    Xu, J.2    Zhang, X.3    Wong, V.W.4    Li, X.5    Lu, A.6    Lu, W.7    Shen, L.8    Li, L.9
  • 179
    • 0035092007 scopus 로고    scopus 로고
    • Potentiation of cholinergic transmission in the rat hippocampus by angiotensin IV and LVV-hemorphin-7
    • Lee J., Chai S.Y., Mendelsohn F.A., Morris M.J., Allen A.M. Potentiation of cholinergic transmission in the rat hippocampus by angiotensin IV and LVV-hemorphin-7. Neuropharmacology 2001, 40:618-623.
    • (2001) Neuropharmacology , vol.40 , pp. 618-623
    • Lee, J.1    Chai, S.Y.2    Mendelsohn, F.A.3    Morris, M.J.4    Allen, A.M.5
  • 181
    • 0030864345 scopus 로고    scopus 로고
    • Expression of angiotensin type-1 (AT1) and type-2 (AT2) receptor mRNAs in the adult rat brain: a functional neuroanatomical review
    • Lenkei Z., Palkovits M., Corvol P., Llorens-Cortes C. Expression of angiotensin type-1 (AT1) and type-2 (AT2) receptor mRNAs in the adult rat brain: a functional neuroanatomical review. Front. Neuroendocrinol. 1997, 18:383-439.
    • (1997) Front. Neuroendocrinol. , vol.18 , pp. 383-439
    • Lenkei, Z.1    Palkovits, M.2    Corvol, P.3    Llorens-Cortes, C.4
  • 182
    • 0037817386 scopus 로고    scopus 로고
    • Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP)
    • Lew R.A., Mustafa T., Ye S., McDowall S.G., Chai S.Y., Albiston A.L. Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP). J. Neurochem. 2003, 86:344-350.
    • (2003) J. Neurochem. , vol.86 , pp. 344-350
    • Lew, R.A.1    Mustafa, T.2    Ye, S.3    McDowall, S.G.4    Chai, S.Y.5    Albiston, A.L.6
  • 183
    • 34047271048 scopus 로고    scopus 로고
    • Neuritogenic activity of chondroitin/dermatan sulfate hybrid chains of embryonic pig brain and their mimicry from shark liver. Involvement of the pleiotrophin and hepatocyte growth factor signaling pathways
    • Li F., Shetty A.K., Sugahara K. Neuritogenic activity of chondroitin/dermatan sulfate hybrid chains of embryonic pig brain and their mimicry from shark liver. Involvement of the pleiotrophin and hepatocyte growth factor signaling pathways. J. Biol. Chem. 2007, 282:2956-2966.
    • (2007) J. Biol. Chem. , vol.282 , pp. 2956-2966
    • Li, F.1    Shetty, A.K.2    Sugahara, K.3
  • 184
    • 0035887033 scopus 로고    scopus 로고
    • Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor
    • Lietha D., Chirgadze D.Y., Mulloy B., Blundell T.L., Gherardi E. Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor. EMBO J. 2001, 20:5543-5555.
    • (2001) EMBO J. , vol.20 , pp. 5543-5555
    • Lietha, D.1    Chirgadze, D.Y.2    Mulloy, B.3    Blundell, T.L.4    Gherardi, E.5
  • 186
    • 20844460621 scopus 로고    scopus 로고
    • The molecular basis of memantine action in Alzheimer's disease and other neurologic disorders: low-affinity, uncompetitive antagonism
    • Lipton S.A. The molecular basis of memantine action in Alzheimer's disease and other neurologic disorders: low-affinity, uncompetitive antagonism. Curr. Alzheimer Res. 2005, 2:155-165.
    • (2005) Curr. Alzheimer Res. , vol.2 , pp. 155-165
    • Lipton, S.A.1
  • 187
    • 0026734672 scopus 로고
    • Structure-function analysis of hepatocyte growth factor: identification of variants that lack mitogenic activity yet retain high affinity receptor binding
    • Lokker N.A., Mark M.R., Luis E.A., Bennett G.L., Robbins K.A., Baker J.B., Godowski P.J. Structure-function analysis of hepatocyte growth factor: identification of variants that lack mitogenic activity yet retain high affinity receptor binding. EMBO J. 1992, 11:2503-2510.
    • (1992) EMBO J. , vol.11 , pp. 2503-2510
    • Lokker, N.A.1    Mark, M.R.2    Luis, E.A.3    Bennett, G.L.4    Robbins, K.A.5    Baker, J.B.6    Godowski, P.J.7
  • 188
    • 27444435057 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition reduces oxidative stress and protects dopaminergic neurons in a 6-hydroxydopamine rat model of Parkinsonism
    • Lopez-Real A., Rey P., Soto-Otero R., Mendez-Alvarez E., Labandeira-Garcia J.L. Angiotensin-converting enzyme inhibition reduces oxidative stress and protects dopaminergic neurons in a 6-hydroxydopamine rat model of Parkinsonism. J. Neurosci. Res. 2005, 81:865-873.
    • (2005) J. Neurosci. Res. , vol.81 , pp. 865-873
    • Lopez-Real, A.1    Rey, P.2    Soto-Otero, R.3    Mendez-Alvarez, E.4    Labandeira-Garcia, J.L.5
  • 189
    • 70349200782 scopus 로고    scopus 로고
    • The replacement of His(4) in angiotensin IV by conformationally constrained residues provides highly potent and selective analogues
    • Lukaszuk A., Demaegdt H., Feytens D., Vanderheyden P., Vauquelin G., Tourwe D. The replacement of His(4) in angiotensin IV by conformationally constrained residues provides highly potent and selective analogues. J. Med. Chem. 2009, 52:5612-5618.
    • (2009) J. Med. Chem. , vol.52 , pp. 5612-5618
    • Lukaszuk, A.1    Demaegdt, H.2    Feytens, D.3    Vanderheyden, P.4    Vauquelin, G.5    Tourwe, D.6
  • 192
    • 0037059771 scopus 로고    scopus 로고
    • The mode of action of heparin and dermatan sulfates in the regulation of hepatocyte growth factor/scatter factor
    • Lyon M., Deakin J.A., Gallagher J.T. The mode of action of heparin and dermatan sulfates in the regulation of hepatocyte growth factor/scatter factor. J. Biol. Chem. 2002, 277:1040-1046.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1040-1046
    • Lyon, M.1    Deakin, J.A.2    Gallagher, J.T.3
  • 193
    • 6344284887 scopus 로고    scopus 로고
    • The interactions of hepatocyte growth factor/scatter factor and its NK1 and NK2 variants with glycosaminoglycans using a modified gel mobility shift assay. Elucidation of the minimal size of binding and activatory oligosaccharides
    • Lyon M., Deakin J.A., Lietha D., Gherardi E., Gallagher J.T. The interactions of hepatocyte growth factor/scatter factor and its NK1 and NK2 variants with glycosaminoglycans using a modified gel mobility shift assay. Elucidation of the minimal size of binding and activatory oligosaccharides. J. Biol. Chem. 2004, 279:43560-43567.
    • (2004) J. Biol. Chem. , vol.279 , pp. 43560-43567
    • Lyon, M.1    Deakin, J.A.2    Lietha, D.3    Gherardi, E.4    Gallagher, J.T.5
  • 194
    • 0028346380 scopus 로고
    • Interaction of hepatocyte growth factor with heparin sulfate. Elucidation of the major heparin sulfate structural determinants
    • Lyon M., Deakin J.A., Mizuno K., Nakamura T., Gallagher J.T. Interaction of hepatocyte growth factor with heparin sulfate. Elucidation of the major heparin sulfate structural determinants. J. Biol. Chem. 1994, 269:11216-11223.
    • (1994) J. Biol. Chem. , vol.269 , pp. 11216-11223
    • Lyon, M.1    Deakin, J.A.2    Mizuno, K.3    Nakamura, T.4    Gallagher, J.T.5
  • 196
    • 0038724909 scopus 로고    scopus 로고
    • C-Met: structure, functions and potential for therapeutic inhibition
    • Ma P.C., Maulik G., Christensen J., Salgia R. C-Met: structure, functions and potential for therapeutic inhibition. Cancer Metastasis Rev. 2003, 22:309-325.
    • (2003) Cancer Metastasis Rev. , vol.22 , pp. 309-325
    • Ma, P.C.1    Maulik, G.2    Christensen, J.3    Salgia, R.4
  • 197
    • 76749087751 scopus 로고    scopus 로고
    • New strategies for Alzheimer's disease and cognitive impairment
    • Maiese K., Chong Z.Z., Hou J., Shang Y.C. New strategies for Alzheimer's disease and cognitive impairment. Oxid. Med. Cell. Longev. 2009, 2:279-289.
    • (2009) Oxid. Med. Cell. Longev. , vol.2 , pp. 279-289
    • Maiese, K.1    Chong, Z.Z.2    Hou, J.3    Shang, Y.C.4
  • 198
    • 0020375803 scopus 로고
    • Basal ganglia disease
    • Marsden C.D. Basal ganglia disease. Lancet 1982, 2:1141-1147.
    • (1982) Lancet , vol.2 , pp. 1141-1147
    • Marsden, C.D.1
  • 199
    • 33845566076 scopus 로고    scopus 로고
    • Loss of embryonic MET signaling alters profiles of hippocampal interneurons
    • Martins G.J., Plachez C., Powell E.M. Loss of embryonic MET signaling alters profiles of hippocampal interneurons. Dev. Neurosci. 2007, 29:143-158.
    • (2007) Dev. Neurosci. , vol.29 , pp. 143-158
    • Martins, G.J.1    Plachez, C.2    Powell, E.M.3
  • 201
    • 0026462368 scopus 로고
    • Hepatocyte growth factor: molecular structure, roles in liver regeneration, and other biological functions
    • Matsumoto K., Nakamura T. Hepatocyte growth factor: molecular structure, roles in liver regeneration, and other biological functions. Crit. Rev. Oncog. 1992, 3:27-54.
    • (1992) Crit. Rev. Oncog. , vol.3 , pp. 27-54
    • Matsumoto, K.1    Nakamura, T.2
  • 202
    • 0037850880 scopus 로고    scopus 로고
    • NK4 (HGF-antagonist/angiogenesis inhibitor) in cancer biology and therapeutics
    • Matsumoto K., Nakamura T. NK4 (HGF-antagonist/angiogenesis inhibitor) in cancer biology and therapeutics. Cancer Sci. 2003, 94:321-327.
    • (2003) Cancer Sci. , vol.94 , pp. 321-327
    • Matsumoto, K.1    Nakamura, T.2
  • 203
    • 50449087162 scopus 로고    scopus 로고
    • Hepatocyte growth factor and Met in tumor biology and therapeutic approach with NK4
    • Matsumoto K., Nakamura T., Sakai K., Nakamura T. Hepatocyte growth factor and Met in tumor biology and therapeutic approach with NK4. Proteomics 2008, 8:3360-3370.
    • (2008) Proteomics , vol.8 , pp. 3360-3370
    • Matsumoto, K.1    Nakamura, T.2    Sakai, K.3    Nakamura, T.4
  • 207
    • 33846362954 scopus 로고    scopus 로고
    • Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system
    • Mehta P.K., Griendling K.K. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am. J. Physiol. Cell Physiol. 2007, 292:C82-C97.
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292 , pp. C82-C97
    • Mehta, P.K.1    Griendling, K.K.2
  • 208
    • 33645103421 scopus 로고    scopus 로고
    • Effects of extracellular matrix-degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic plasticity
    • Meighan S.E., Meighan P.C., Choudhury P., Davis C.J., Olson M.L., Zornes P.A., Wright J.W., Harding J.W. Effects of extracellular matrix-degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic plasticity. J. Neurochem. 2006, 96:1227-1241.
    • (2006) J. Neurochem. , vol.96 , pp. 1227-1241
    • Meighan, S.E.1    Meighan, P.C.2    Choudhury, P.3    Davis, C.J.4    Olson, M.L.5    Zornes, P.A.6    Wright, J.W.7    Harding, J.W.8
  • 209
    • 34548253841 scopus 로고    scopus 로고
    • Effects of matrix metalloproteinase inhibition on short- and long-term plasticity of schaffer collateral/CA1 synapses
    • Meighan P.C., Meighan S.E., Davis C.J., Wright J.W., Harding J.W. Effects of matrix metalloproteinase inhibition on short- and long-term plasticity of schaffer collateral/CA1 synapses. J. Neurochem. 2007, 102:2085-2096.
    • (2007) J. Neurochem. , vol.102 , pp. 2085-2096
    • Meighan, P.C.1    Meighan, S.E.2    Davis, C.J.3    Wright, J.W.4    Harding, J.W.5
  • 211
    • 34247876141 scopus 로고    scopus 로고
    • Therapies for Alzheimer's disease
    • Melnikova I. Therapies for Alzheimer's disease. Nat. Rev. Drug. Discov. 2007, 6:341-342.
    • (2007) Nat. Rev. Drug. Discov. , vol.6 , pp. 341-342
    • Melnikova, I.1
  • 214
    • 0037146905 scopus 로고    scopus 로고
    • Neuroprotection by memantine against neurodegeneration induced by beta-amyloid (1-40)
    • Miguel-Hidalgo J.J., Alvarez X.A., Cacabelos R., Quack G. Neuroprotection by memantine against neurodegeneration induced by beta-amyloid (1-40). Brain Res. 2002, 958:210-221.
    • (2002) Brain Res. , vol.958 , pp. 210-221
    • Miguel-Hidalgo, J.J.1    Alvarez, X.A.2    Cacabelos, R.3    Quack, G.4
  • 215
    • 0027289115 scopus 로고
    • Molecular cloning and sequence analysis of the cDNA for a human serine protease responsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XII
    • Miyazawa K., Shimomura T., Kitamura A., Kondo J., Morimoto Y., Kitamura N. Molecular cloning and sequence analysis of the cDNA for a human serine protease responsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XII. J. Biol. Chem. 1993, 268:10024-10028.
    • (1993) J. Biol. Chem. , vol.268 , pp. 10024-10028
    • Miyazawa, K.1    Shimomura, T.2    Kitamura, A.3    Kondo, J.4    Morimoto, Y.5    Kitamura, N.6
  • 216
    • 0000135127 scopus 로고    scopus 로고
    • Protection of hippocampal neurons from ischemia-induced delayed neuronal death by hepatocyte growth factor: a novel neurotrophic factor
    • Miyazawa T., Matsumoto K., Ohmichi H., Katoh H., Yamashima T., Hakamura T. Protection of hippocampal neurons from ischemia-induced delayed neuronal death by hepatocyte growth factor: a novel neurotrophic factor. J. Cereb. Blood Flow Metab. 1998, 18:345-348.
    • (1998) J. Cereb. Blood Flow Metab. , vol.18 , pp. 345-348
    • Miyazawa, T.1    Matsumoto, K.2    Ohmichi, H.3    Katoh, H.4    Yamashima, T.5    Hakamura, T.6
  • 217
    • 52049123764 scopus 로고    scopus 로고
    • HGF as a renotrophic and anti-fibrotic regulator in chronic renal disease
    • Mizuno S., Matsumoto K., Nakamura T. HGF as a renotrophic and anti-fibrotic regulator in chronic renal disease. Front. Biosci. 2008, 13:7072-7086.
    • (2008) Front. Biosci. , vol.13 , pp. 7072-7086
    • Mizuno, S.1    Matsumoto, K.2    Nakamura, T.3
  • 218
    • 0030600013 scopus 로고    scopus 로고
    • Angiotensin IV inhibits neurite outgrowth in cultured embryonic chicken sympathetic neurons
    • Moeller I., Small D.H., Reed G., Harding J.W., Mendelsohn F.A., Chai S.Y. Angiotensin IV inhibits neurite outgrowth in cultured embryonic chicken sympathetic neurons. Brain Res. 1996, 725:61-66.
    • (1996) Brain Res. , vol.725 , pp. 61-66
    • Moeller, I.1    Small, D.H.2    Reed, G.3    Harding, J.W.4    Mendelsohn, F.A.5    Chai, S.Y.6
  • 219
    • 70249088004 scopus 로고    scopus 로고
    • Effects of angiotensin II receptor blockers on dementia
    • Mogi M., Horiuchi M. Effects of angiotensin II receptor blockers on dementia. Hypertens. Res. 2009, 32:738-740.
    • (2009) Hypertens. Res. , vol.32 , pp. 738-740
    • Mogi, M.1    Horiuchi, M.2
  • 220
    • 0033635302 scopus 로고    scopus 로고
    • Effect of apolipoprotein E allele epsilon4 on the initial phase of amyloid beta-protein accumulation in the human brain
    • Morishima-Kawashima M., Oshima N., Ogata H., Yamaguchi H., Yoshimura M., Sugihara S., Ihara Y. Effect of apolipoprotein E allele epsilon4 on the initial phase of amyloid beta-protein accumulation in the human brain. Am. J. Pathol. 2000, 157:2093-2099.
    • (2000) Am. J. Pathol. , vol.157 , pp. 2093-2099
    • Morishima-Kawashima, M.1    Oshima, N.2    Ogata, H.3    Yamaguchi, H.4    Yoshimura, M.5    Sugihara, S.6    Ihara, Y.7
  • 223
    • 33745192816 scopus 로고    scopus 로고
    • Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of Parkinsonism
    • Munoz A., Rey P., Guerra M.J. Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of Parkinsonism. Neuropharmacology 2006, 51:112-120.
    • (2006) Neuropharmacology , vol.51 , pp. 112-120
    • Munoz, A.1    Rey, P.2    Guerra, M.J.3
  • 224
    • 0035949650 scopus 로고    scopus 로고
    • Are ACE inhibitors a magic bullet against oxidative stress?
    • Munzel T., Kearney F.J. Are ACE inhibitors a magic bullet against oxidative stress?. Circulation 2001, 104:1571-1574.
    • (2001) Circulation , vol.104 , pp. 1571-1574
    • Munzel, T.1    Kearney, F.J.2
  • 226
    • 77955102398 scopus 로고    scopus 로고
    • The discovery of hepatocyte growth factor (HGF) and its significance for cell biology, life sciences and clinical medicine
    • Nakamura T., Mizuno S. The discovery of hepatocyte growth factor (HGF) and its significance for cell biology, life sciences and clinical medicine. Proc. Jpn. Acad., Ser. B Phys. Biol. Sci. 2010, 86:588-610.
    • (2010) Proc. Jpn. Acad., Ser. B Phys. Biol. Sci. , vol.86 , pp. 588-610
    • Nakamura, T.1    Mizuno, S.2
  • 227
    • 0034526510 scopus 로고    scopus 로고
    • Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF
    • Nakamura T., Mizuno S., Matsumoto K., Sawa Y., Matsuda H., Nakamura T. Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF. J. Clin. Invest. 2000, 106:1511-1519.
    • (2000) J. Clin. Invest. , vol.106 , pp. 1511-1519
    • Nakamura, T.1    Mizuno, S.2    Matsumoto, K.3    Sawa, Y.4    Matsuda, H.5    Nakamura, T.6
  • 228
    • 0021285134 scopus 로고
    • Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
    • Nakamura T., Nawa K., Ichihara A. Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochem. Biophys. Res. Commun. 1984, 122:1450-1459.
    • (1984) Biochem. Biophys. Res. Commun. , vol.122 , pp. 1450-1459
    • Nakamura, T.1    Nawa, K.2    Ichihara, A.3
  • 231
  • 232
    • 0028027798 scopus 로고
    • Angiotensin IV reverses the acute cerebral blood flow reduction after experimental subarachnoid hemorrhage in the rat
    • Naveri L., Stromberg C., Saavedra J.M. Angiotensin IV reverses the acute cerebral blood flow reduction after experimental subarachnoid hemorrhage in the rat. J. Cereb. Blood Flow Metab. 1994, 14:1096-1099.
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 1096-1099
    • Naveri, L.1    Stromberg, C.2    Saavedra, J.M.3
  • 233
    • 75649105019 scopus 로고    scopus 로고
    • Current treatment and recent clinical research in Alzheimer's disease
    • Neugroschl J., Sano M. Current treatment and recent clinical research in Alzheimer's disease. Mt. Sinai J. Med. 2010, 77:3-16.
    • (2010) Mt. Sinai J. Med. , vol.77 , pp. 3-16
    • Neugroschl, J.1    Sano, M.2
  • 234
    • 12544252127 scopus 로고    scopus 로고
    • Duodenal levodopa infusion monotherapy vs oral polypharmacy in advanced Parkinson disease
    • Nyholm D. Duodenal levodopa infusion monotherapy vs oral polypharmacy in advanced Parkinson disease. Neurology 2005, 64:216-223.
    • (2005) Neurology , vol.64 , pp. 216-223
    • Nyholm, D.1
  • 236
    • 84878631527 scopus 로고    scopus 로고
    • Angiotensin (1-7) and other angiotensin peptides
    • Ohishi M., Yamamoto K., Rakugi H. Angiotensin (1-7) and other angiotensin peptides. Curr. Pharm. Des. 2013, 19:3060-3064.
    • (2013) Curr. Pharm. Des. , vol.19 , pp. 3060-3064
    • Ohishi, M.1    Yamamoto, K.2    Rakugi, H.3
  • 237
    • 54249095506 scopus 로고    scopus 로고
    • Effect of hepatocyte growth factor on gene expression of extracellular matrix during wound healing of the injured rat vocal fold
    • Ohno T., French L.C., Hirano S., Ossoff R.H., Rousseau B. Effect of hepatocyte growth factor on gene expression of extracellular matrix during wound healing of the injured rat vocal fold. Ann. Otol. Rhinol. Laryngol. 2008, 117:696-702.
    • (2008) Ann. Otol. Rhinol. Laryngol. , vol.117 , pp. 696-702
    • Ohno, T.1    French, L.C.2    Hirano, S.3    Ossoff, R.H.4    Rousseau, B.5
  • 239
    • 66949117423 scopus 로고    scopus 로고
    • The scientific and clinical basis for the treatment of Parkinson disease
    • Olanow C.W., Stern M.B., Sethi K. The scientific and clinical basis for the treatment of Parkinson disease. Neurology 2009, 72(21 Suppl. 4):S1-S136.
    • (2009) Neurology , vol.72 , Issue.21 , pp. S1-S136
    • Olanow, C.W.1    Stern, M.B.2    Sethi, K.3
  • 240
    • 78049459620 scopus 로고    scopus 로고
    • 1-angiotensin IV mitigates scopolamine-induced spatial working memory deficits
    • 1-angiotensin IV mitigates scopolamine-induced spatial working memory deficits. Peptides 2010, 31:2209-2215.
    • (2010) Peptides , vol.31 , pp. 2209-2215
    • Olson, M.L.1    Cero, I.J.2
  • 242
    • 0017578611 scopus 로고
    • Design of specific inhibitors of angiotensin converting enzyme: new class of orally active antihypertensive agents
    • Ondetti M.A., Rubin B., Cushman D.W. Design of specific inhibitors of angiotensin converting enzyme: new class of orally active antihypertensive agents. Science 1977, 196:441-444.
    • (1977) Science , vol.196 , pp. 441-444
    • Ondetti, M.A.1    Rubin, B.2    Cushman, D.W.3
  • 243
    • 0002671581 scopus 로고
    • A crystalline pressor substance (angiotonin) resulting from the action between renin and renin-activator
    • Page I.H., Helmer O.M. A crystalline pressor substance (angiotonin) resulting from the action between renin and renin-activator. J. Exp. Med. 1940, 71:29-42.
    • (1940) J. Exp. Med. , vol.71 , pp. 29-42
    • Page, I.H.1    Helmer, O.M.2
  • 245
    • 39149117756 scopus 로고    scopus 로고
    • Amyloid beta peptides and glutamaterigic synaptic dysregulation
    • Parameshwaran K., Dhanasekaran M., Suppiramaniam V. Amyloid beta peptides and glutamaterigic synaptic dysregulation. Exp. Neurol. 2008, 210:7-13.
    • (2008) Exp. Neurol. , vol.210 , pp. 7-13
    • Parameshwaran, K.1    Dhanasekaran, M.2    Suppiramaniam, V.3
  • 251
    • 3142761786 scopus 로고    scopus 로고
    • A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation
    • Peschard P., Ishiyama N., Lin T., Lipkowitz S., Park M. A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation. J. Biol. Chem. 2004, 279:29565-29571.
    • (2004) J. Biol. Chem. , vol.279 , pp. 29565-29571
    • Peschard, P.1    Ishiyama, N.2    Lin, T.3    Lipkowitz, S.4    Park, M.5
  • 252
    • 0023161147 scopus 로고
    • Functions of angiotensin in the central nervous system
    • Phillips M.I. Functions of angiotensin in the central nervous system. Annu. Rev. Physiol. 1987, 49:413-435.
    • (1987) Annu. Rev. Physiol. , vol.49 , pp. 413-435
    • Phillips, M.I.1
  • 253
    • 0017184082 scopus 로고
    • Specific angiotensin II receptive neurons in the cat subfornical organ
    • Phillips M.I., Felix D. Specific angiotensin II receptive neurons in the cat subfornical organ. Brain Res. 1976, 109:531-540.
    • (1976) Brain Res. , vol.109 , pp. 531-540
    • Phillips, M.I.1    Felix, D.2
  • 254
    • 84855815646 scopus 로고    scopus 로고
    • Bridging the pathophysiology of Alzheimer's disease with vascular pathology: the feed-back, the feed-forward, and oxidative stress
    • Polidori M.C., Pientka L. Bridging the pathophysiology of Alzheimer's disease with vascular pathology: the feed-back, the feed-forward, and oxidative stress. J. Alzheimers Dis. 2012, 28:1-9.
    • (2012) J. Alzheimers Dis. , vol.28 , pp. 1-9
    • Polidori, M.C.1    Pientka, L.2
  • 255
    • 0028351702 scopus 로고
    • A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
    • Ponzetto C., Bardelli A., Zhen Z., Maina F., Dalla Zonca P., Giordano S., Graziani A., Panayotou G., Comoglio P.M. A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family. Cell 1994, 77:261-271.
    • (1994) Cell , vol.77 , pp. 261-271
    • Ponzetto, C.1    Bardelli, A.2    Zhen, Z.3    Maina, F.4    Dalla Zonca, P.5    Giordano, S.6    Graziani, A.7    Panayotou, G.8    Comoglio, P.M.9
  • 256
    • 84859901750 scopus 로고    scopus 로고
    • Economic evaluation of treatment options in patients with Alzheimer's disease: a systematic review of cost-effetiveness analyses
    • Pouryamout L., Dams J., Wasem J., Dodel R., Neumann A. Economic evaluation of treatment options in patients with Alzheimer's disease: a systematic review of cost-effetiveness analyses. Drugs 2012, 72:789-802.
    • (2012) Drugs , vol.72 , pp. 789-802
    • Pouryamout, L.1    Dams, J.2    Wasem, J.3    Dodel, R.4    Neumann, A.5
  • 257
    • 0041411415 scopus 로고    scopus 로고
    • Differential regulation of thalamic and cortical axonal growth by hepatocyte growth factor/scatter factor
    • Powell E.M., Muhlfriedel S., Bolz J., Levitt P. Differential regulation of thalamic and cortical axonal growth by hepatocyte growth factor/scatter factor. Dev. Neurosci. 2003, 25:197-206.
    • (2003) Dev. Neurosci. , vol.25 , pp. 197-206
    • Powell, E.M.1    Muhlfriedel, S.2    Bolz, J.3    Levitt, P.4
  • 258
    • 0035968623 scopus 로고    scopus 로고
    • Randomized trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack
    • PROGRESS Collaborative Group Randomized trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack. Lancet 2001, 358:1033-1041.
    • (2001) Lancet , vol.358 , pp. 1033-1041
  • 259
    • 48949083569 scopus 로고    scopus 로고
    • Involvement of angiotensin II and angiotensin IV in producing the individual characteristics of defensive and feeding behavior in rats
    • Prozherina Y.A. Involvement of angiotensin II and angiotensin IV in producing the individual characteristics of defensive and feeding behavior in rats. Neurosci. Behav. Physiol. 2008, 38:563-572.
    • (2008) Neurosci. Behav. Physiol. , vol.38 , pp. 563-572
    • Prozherina, Y.A.1
  • 260
    • 0346463000 scopus 로고    scopus 로고
    • NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia
    • Qin L., Liu Y., Wang T., Wei S.J., Block M.L., Wilson B., Liu B., Hong J.S. NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia. J. Biol. Chem. 2004, 279:1415-1421.
    • (2004) J. Biol. Chem. , vol.279 , pp. 1415-1421
    • Qin, L.1    Liu, Y.2    Wang, T.3    Wei, S.J.4    Block, M.L.5    Wilson, B.6    Liu, B.7    Hong, J.S.8
  • 261
    • 20444440685 scopus 로고    scopus 로고
    • Mechanisms of disease: local renin-angiotensin-aldosterone systems and the pathogenesis and treatment of cardiovascular disease
    • Re R.N. Mechanisms of disease: local renin-angiotensin-aldosterone systems and the pathogenesis and treatment of cardiovascular disease. Nat. Clin. Pract. Cardiovasc. Med. 2004, 1:42-47.
    • (2004) Nat. Clin. Pract. Cardiovasc. Med. , vol.1 , pp. 42-47
    • Re, R.N.1
  • 262
    • 0034023229 scopus 로고    scopus 로고
    • The angiotensin converting enzyme (ACE) inhibitor, perindopril, modifies the clinical features of Parkinson's disease
    • Reardon K.A., Mendelsohn F.A., Chai S.Y., Horne M.K. The angiotensin converting enzyme (ACE) inhibitor, perindopril, modifies the clinical features of Parkinson's disease. Aust. N. Z. J. Med. 2000, 30:48-53.
    • (2000) Aust. N. Z. J. Med. , vol.30 , pp. 48-53
    • Reardon, K.A.1    Mendelsohn, F.A.2    Chai, S.Y.3    Horne, M.K.4
  • 264
    • 0021277915 scopus 로고
    • Inhibition of aminopeptidases by amastatin and bestatin derivatives, effect of inhibitor structure on slow-binding processes
    • Rich D.H., Moon B.J., Harbeson S. Inhibition of aminopeptidases by amastatin and bestatin derivatives, effect of inhibitor structure on slow-binding processes. J. Med. Chem. 1984, 27:417-422.
    • (1984) J. Med. Chem. , vol.27 , pp. 417-422
    • Rich, D.H.1    Moon, B.J.2    Harbeson, S.3
  • 266
    • 34548620779 scopus 로고    scopus 로고
    • Mechanism of 6-hydroxydopamine neurotoxicity: the role of NADPH oxidase and microglical activation in 6-hydroxydopamine-induced degeneration of dopaminergic neurons
    • Rodriguez-Pallares J., Parga J.A., Munoz A., Rey P., Guerra M.J., Labandeira-Garcia J.L. Mechanism of 6-hydroxydopamine neurotoxicity: the role of NADPH oxidase and microglical activation in 6-hydroxydopamine-induced degeneration of dopaminergic neurons. J. Neurochem. 2007, 103:145-156.
    • (2007) J. Neurochem. , vol.103 , pp. 145-156
    • Rodriguez-Pallares, J.1    Parga, J.A.2    Munoz, A.3    Rey, P.4    Guerra, M.J.5    Labandeira-Garcia, J.L.6
  • 267
    • 4644306054 scopus 로고    scopus 로고
    • Angiotensin II increases differentiation of dopaminergic neurons from mesencephalic precursors via angiotensin type 2 receptors
    • Rodriguez-Pallares J., Quiroz C.R., Parga J.A., Guerra M.J., Labandeira-Garcia J.L. Angiotensin II increases differentiation of dopaminergic neurons from mesencephalic precursors via angiotensin type 2 receptors. Eur. J. Neurosci. 2004, 20:1489-1498.
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 1489-1498
    • Rodriguez-Pallares, J.1    Quiroz, C.R.2    Parga, J.A.3    Guerra, M.J.4    Labandeira-Garcia, J.L.5
  • 270
    • 0038697632 scopus 로고    scopus 로고
    • How to make tubes: signaling by the Met receptor tyrosine kinase
    • Rosario M., Birchmeier W. How to make tubes: signaling by the Met receptor tyrosine kinase. Trends Cell. Biol. 2003, 13:328-335.
    • (2003) Trends Cell. Biol. , vol.13 , pp. 328-335
    • Rosario, M.1    Birchmeier, W.2
  • 271
    • 84859712858 scopus 로고    scopus 로고
    • CSF biomarkers for amyloid and tau pathology in Alzheimer's disease
    • Rosenmann H. CSF biomarkers for amyloid and tau pathology in Alzheimer's disease. J. Mol. Neurosci. 2012, 47:1-14.
    • (2012) J. Mol. Neurosci. , vol.47 , pp. 1-14
    • Rosenmann, H.1
  • 272
    • 0036009738 scopus 로고    scopus 로고
    • Angiotensin AT2 receptor ligands: do they have potential as future treatments for neurological disease?
    • Rosenstiel P., Gallinat S., Arit A., Unger T., Sievers J., Lucius R. Angiotensin AT2 receptor ligands: do they have potential as future treatments for neurological disease?. CNS Drugs 2002, 16:145-153.
    • (2002) CNS Drugs , vol.16 , pp. 145-153
    • Rosenstiel, P.1    Gallinat, S.2    Arit, A.3    Unger, T.4    Sievers, J.5    Lucius, R.6
  • 275
    • 0033619674 scopus 로고    scopus 로고
    • Emerging features of brain angiotensin receptors
    • Saavedra J.M. Emerging features of brain angiotensin receptors. Regul. Pept. 1999, 85:31-45.
    • (1999) Regul. Pept. , vol.85 , pp. 31-45
    • Saavedra, J.M.1
  • 276
    • 78249257305 scopus 로고    scopus 로고
    • Alzheimer's disease amyloid hypothesis at crossroads: where do we go from here?
    • Sacena U. Alzheimer's disease amyloid hypothesis at crossroads: where do we go from here?. Expert Open. Ther. Targets 2010, 14:1273-1277.
    • (2010) Expert Open. Ther. Targets , vol.14 , pp. 1273-1277
    • Sacena, U.1
  • 277
    • 78049463436 scopus 로고    scopus 로고
    • Expression of hepatocyte growth factor in the serum and cerebrospinal fluid of patients with Parkinson's disease
    • Salehi Z., Rajaei F. Expression of hepatocyte growth factor in the serum and cerebrospinal fluid of patients with Parkinson's disease. J. Clin. Neurosci. 2010, 17:1553-1556.
    • (2010) J. Clin. Neurosci. , vol.17 , pp. 1553-1556
    • Salehi, Z.1    Rajaei, F.2
  • 279
    • 0027952644 scopus 로고
    • Regulation of angiotensin II receptors in rat brain during dietary sodium changes
    • I-137-I-141
    • Sandberg K., Ji H., Catt K.J. Regulation of angiotensin II receptors in rat brain during dietary sodium changes. Hypertension 1994, 23:I-137-I-141.
    • (1994) Hypertension , vol.23
    • Sandberg, K.1    Ji, H.2    Catt, K.J.3
  • 280
    • 0027330018 scopus 로고
    • AT4 receptor binding characteristics: d-amino acid- and glycine-substituted peptides
    • Sardinia M.F., Hanesworth J.M., Krebs L.T., Harding J.W. AT4 receptor binding characteristics: d-amino acid- and glycine-substituted peptides. Peptides 1993, 14:949-954.
    • (1993) Peptides , vol.14 , pp. 949-954
    • Sardinia, M.F.1    Hanesworth, J.M.2    Krebs, L.T.3    Harding, J.W.4
  • 281
    • 0028173398 scopus 로고
    • AT4 receptor structure-binding relationship: N-terminal-modified angiotensin IV analogues
    • Sardinia M.F., Hanesworth J.M., Krishnan F., Harding J.W. AT4 receptor structure-binding relationship: N-terminal-modified angiotensin IV analogues. Peptides 1994, 15:1399-1406.
    • (1994) Peptides , vol.15 , pp. 1399-1406
    • Sardinia, M.F.1    Hanesworth, J.M.2    Krishnan, F.3    Harding, J.W.4
  • 283
    • 67449104699 scopus 로고    scopus 로고
    • Etiology and pathogenesis of Parkinson disease
    • Schapira A.H. Etiology and pathogenesis of Parkinson disease. Neurol. Clin. 2009, 27:583-603.
    • (2009) Neurol. Clin. , vol.27 , pp. 583-603
    • Schapira, A.H.1
  • 284
    • 35748959415 scopus 로고    scopus 로고
    • Mixed brain pathologies account for most dementia cases in community-dwelling older persons
    • Schneider J.A., Arvanitakis Z., Bang W., Bennett D.A. Mixed brain pathologies account for most dementia cases in community-dwelling older persons. Neurology 2007, 69:2197-2204.
    • (2007) Neurology , vol.69 , pp. 2197-2204
    • Schneider, J.A.1    Arvanitakis, Z.2    Bang, W.3    Bennett, D.A.4
  • 285
    • 84865721851 scopus 로고    scopus 로고
    • An alternative approach to drug discovery for Alzheimer's disease dementia
    • Schubert D., Maher P. An alternative approach to drug discovery for Alzheimer's disease dementia. Future Med. Chem. 2012, 4:1681-1688.
    • (2012) Future Med. Chem. , vol.4 , pp. 1681-1688
    • Schubert, D.1    Maher, P.2
  • 287
    • 0025862023 scopus 로고
    • Organization of the human hepatocyte growth factor-encoding gene
    • Seki T., Hagiya M., Shimonishi M., Nakamura T., Shimizu S. Organization of the human hepatocyte growth factor-encoding gene. Gene 1991, 102:213-219.
    • (1991) Gene , vol.102 , pp. 213-219
    • Seki, T.1    Hagiya, M.2    Shimonishi, M.3    Nakamura, T.4    Shimizu, S.5
  • 288
    • 84903781511 scopus 로고    scopus 로고
    • Mechanisms of synaptic dysfunction and excitotoxicity in Huntington's disease
    • Epub ahead of print
    • Sepers M.D., Raymond L.A. Mechanisms of synaptic dysfunction and excitotoxicity in Huntington's disease. Drug Discov. Today 2014, Epub ahead of print.
    • (2014) Drug Discov. Today
    • Sepers, M.D.1    Raymond, L.A.2
  • 291
    • 77951725826 scopus 로고    scopus 로고
    • Hepatocyte growth factor in synaptic plasticity and Alzheimer's disease
    • Sharma S.K. Hepatocyte growth factor in synaptic plasticity and Alzheimer's disease. Sci. World J. 2010, 10:457-461.
    • (2010) Sci. World J. , vol.10 , pp. 457-461
    • Sharma, S.K.1
  • 292
    • 41449090165 scopus 로고    scopus 로고
    • Biochemical basis for the functional switch that regulates hepatocyte growth factor receptor tyrosine kinase activation
    • Sheth P.R., Hays J.L., Elferink L.A., Watowich S.J. Biochemical basis for the functional switch that regulates hepatocyte growth factor receptor tyrosine kinase activation. Biochemistry 2008, 47:4028-4038.
    • (2008) Biochemistry , vol.47 , pp. 4028-4038
    • Sheth, P.R.1    Hays, J.L.2    Elferink, L.A.3    Watowich, S.J.4
  • 293
    • 78049329501 scopus 로고    scopus 로고
    • Intrathecal injection of hepatocyte growth factor gene-modified marrow stromal cells attenuates neurologic injury induced by transient spinal cord ischemia in rabbits
    • Shi E., Jiang X., Wang L., Akuzawa S., Nakajima Y., Kazui T. Intrathecal injection of hepatocyte growth factor gene-modified marrow stromal cells attenuates neurologic injury induced by transient spinal cord ischemia in rabbits. Anesthesiology 2010, 113:1109-1117.
    • (2010) Anesthesiology , vol.113 , pp. 1109-1117
    • Shi, E.1    Jiang, X.2    Wang, L.3    Akuzawa, S.4    Nakajima, Y.5    Kazui, T.6
  • 294
    • 82055198527 scopus 로고    scopus 로고
    • Experimental and clinical application of plasmid DNA in the field of central nervous diseases
    • Shimamura M., Sato N., Morishita R. Experimental and clinical application of plasmid DNA in the field of central nervous diseases. Curr. Gene Ther. 2011, 11:491-500.
    • (2011) Curr. Gene Ther. , vol.11 , pp. 491-500
    • Shimamura, M.1    Sato, N.2    Morishita, R.3
  • 296
    • 0242694513 scopus 로고    scopus 로고
    • Suppression of met expression: a possible cancer treatment
    • Shinomiya N., Vande Woude G.F. Suppression of met expression: a possible cancer treatment. Clin. Cancer Res. 2003, 9(14):5085-5090.
    • (2003) Clin. Cancer Res. , vol.9 , Issue.14 , pp. 5085-5090
    • Shinomiya, N.1    Vande Woude, G.F.2
  • 299
    • 0000586975 scopus 로고
    • The preparation, purification and amino acid sequence of polypeptide renin substrate
    • Skeggs L.T., Kahn J.R., Lentz K.E., Shumway N.P. The preparation, purification and amino acid sequence of polypeptide renin substrate. J. Exp. Med. 1957, 106:439-453.
    • (1957) J. Exp. Med. , vol.106 , pp. 439-453
    • Skeggs, L.T.1    Kahn, J.R.2    Lentz, K.E.3    Shumway, N.P.4
  • 300
    • 0027437547 scopus 로고
    • Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development
    • Sonnenberg E., Meyer D., Weidner K.M., Birchmeier C. Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development. J. Cell Biol. 1993, 123:223-235.
    • (1993) J. Cell Biol. , vol.123 , pp. 223-235
    • Sonnenberg, E.1    Meyer, D.2    Weidner, K.M.3    Birchmeier, C.4
  • 301
    • 84884286721 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitors and Alzheimer's disease progression in older adults: results from the Reseau sur la Maladie d-Alzheimer Francais cohort
    • Soto M.E., van Kan G.A., Nourhashemi F., Gillette-Guyonnet S., Cesari M., Cantet C., Rolland Y., Velias B. Angiotensin-converting enzyme inhibitors and Alzheimer's disease progression in older adults: results from the Reseau sur la Maladie d-Alzheimer Francais cohort. J. Am. Geriatr. Soc. 2013, 61:1482-1488.
    • (2013) J. Am. Geriatr. Soc. , vol.61 , pp. 1482-1488
    • Soto, M.E.1    van Kan, G.A.2    Nourhashemi, F.3    Gillette-Guyonnet, S.4    Cesari, M.5    Cantet, C.6    Rolland, Y.7    Velias, B.8
  • 303
    • 42049097442 scopus 로고    scopus 로고
    • The significance of brain aminopeptidases in the regulation of the actions of angiotensin peptides in the brain
    • Speth R.C., Karamyan V.T. The significance of brain aminopeptidases in the regulation of the actions of angiotensin peptides in the brain. Heart Fail. Rev. 2008, 13:299-309.
    • (2008) Heart Fail. Rev. , vol.13 , pp. 299-309
    • Speth, R.C.1    Karamyan, V.T.2
  • 304
    • 84885608405 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: problems and prospects
    • Sreedharan J., Brown R.H. Amyotrophic lateral sclerosis: problems and prospects. Ann. Neurol. 2013, 74:309-316.
    • (2013) Ann. Neurol. , vol.74 , pp. 309-316
    • Sreedharan, J.1    Brown, R.H.2
  • 305
    • 3142595278 scopus 로고    scopus 로고
    • Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor
    • Stamos J., Lazarus R.A., Yao X., Kirchhofer D., Wiesmann C. Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor. EMBO J. 2004, 23:2325-2335.
    • (2004) EMBO J. , vol.23 , pp. 2325-2335
    • Stamos, J.1    Lazarus, R.A.2    Yao, X.3    Kirchhofer, D.4    Wiesmann, C.5
  • 306
    • 0022269174 scopus 로고
    • An epithelial scatter factor released by embryo fibroblasts
    • Stoker M., Perryman M. An epithelial scatter factor released by embryo fibroblasts. J. Cell Sci. 1985, 77:209-223.
    • (1985) J. Cell Sci. , vol.77 , pp. 209-223
    • Stoker, M.1    Perryman, M.2
  • 307
    • 33746407274 scopus 로고    scopus 로고
    • Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats
    • Stragier B., Clinckers R., Meurs A., De Bundel D., Sarre S., Ebinger G., Michotte Y., Smolders I. Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats. J. Neurochem. 2006, 98:1100-1113.
    • (2006) J. Neurochem. , vol.98 , pp. 1100-1113
    • Stragier, B.1    Clinckers, R.2    Meurs, A.3    De Bundel, D.4    Sarre, S.5    Ebinger, G.6    Michotte, Y.7    Smolders, I.8
  • 311
    • 0021848746 scopus 로고
    • A rat brain isozyme of angiotensin-converting enzyme. Unique specificity for amidated peptide substrates
    • Strittmatter S.M., Thiele E.A., Kapiloff M.S., Snyder S.H. A rat brain isozyme of angiotensin-converting enzyme. Unique specificity for amidated peptide substrates. J. Biol. Chem. 1985, 260:9825-9832.
    • (1985) J. Biol. Chem. , vol.260 , pp. 9825-9832
    • Strittmatter, S.M.1    Thiele, E.A.2    Kapiloff, M.S.3    Snyder, S.H.4
  • 312
    • 0029922733 scopus 로고    scopus 로고
    • Effects of discrete kainic acid-induced hippocampal lesions on spatial and contextual learning and memory in rats
    • Stubley-Weatherly L., Harding J.W., Wright J.W. Effects of discrete kainic acid-induced hippocampal lesions on spatial and contextual learning and memory in rats. Brain Res. 1996, 716:29-38.
    • (1996) Brain Res. , vol.716 , pp. 29-38
    • Stubley-Weatherly, L.1    Harding, J.W.2    Wright, J.W.3
  • 315
    • 0036703771 scopus 로고    scopus 로고
    • Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS
    • Sun W., Funakoshi H., Nakamura T. Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS. J. Neurosci. 2002, 22:6537-6548.
    • (2002) J. Neurosci. , vol.22 , pp. 6537-6548
    • Sun, W.1    Funakoshi, H.2    Nakamura, T.3
  • 318
    • 33244461047 scopus 로고    scopus 로고
    • Intraventricular administration of hepatocyte growth factor treats mouse communicating hydrocephalus induced by transforming growth factor beta1
    • Tada R., Zhan H., Tanaka Y., Hongo K., Matsumoto K., Nakamura T. Intraventricular administration of hepatocyte growth factor treats mouse communicating hydrocephalus induced by transforming growth factor beta1. Neurobiol. Dis. 2006, 21:576-585.
    • (2006) Neurobiol. Dis. , vol.21 , pp. 576-585
    • Tada, R.1    Zhan, H.2    Tanaka, Y.3    Hongo, K.4    Matsumoto, K.5    Nakamura, T.6
  • 319
    • 35948933946 scopus 로고    scopus 로고
    • Ischemic brain injury and hepatocyte growth factor
    • Takeo S., Takagi N., Takagi K. Ischemic brain injury and hepatocyte growth factor. Yakugaku Zasshi 2007, 127:1813-1823.
    • (2007) Yakugaku Zasshi , vol.127 , pp. 1813-1823
    • Takeo, S.1    Takagi, N.2    Takagi, K.3
  • 320
    • 43049183518 scopus 로고    scopus 로고
    • Alleviation of aβ-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model
    • Takeuchi E., Sato N., Shimamura M., Kurinami H., Takeda S., Shinohara M. Alleviation of aβ-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model. Gene Ther. 2008, 15:561-571.
    • (2008) Gene Ther. , vol.15 , pp. 561-571
    • Takeuchi, E.1    Sato, N.2    Shimamura, M.3    Kurinami, H.4    Takeda, S.5    Shinohara, M.6
  • 321
    • 10444265867 scopus 로고    scopus 로고
    • Angiotensin peptides modulatory system: how is it implicated in the control of seizure susceptibility?
    • Tchekalarova J.D., Georgiev V.P. Angiotensin peptides modulatory system: how is it implicated in the control of seizure susceptibility?. Life Sci. 2005, 76:955-970.
    • (2005) Life Sci. , vol.76 , pp. 955-970
    • Tchekalarova, J.D.1    Georgiev, V.P.2
  • 322
    • 33751014306 scopus 로고    scopus 로고
    • Ang II and Ang III modulate PTZ seizure threshold in non-stressed and stressed mice: possible involvement of noradrenergic mechanism
    • Tchekalarova J.D., Georgiev V.P. Ang II and Ang III modulate PTZ seizure threshold in non-stressed and stressed mice: possible involvement of noradrenergic mechanism. Neuropeptides 2006, 40:339-348.
    • (2006) Neuropeptides , vol.40 , pp. 339-348
    • Tchekalarova, J.D.1    Georgiev, V.P.2
  • 324
    • 0033550886 scopus 로고    scopus 로고
    • The expression of mRNAs for hepatocyte growth factor/scatter factor, its receptor c-met, and one of its activators tissue-type plasminogen activator show a systematic relationship in the developing and adult cerebral cortex and hippocampus
    • Thewke E.P., Seeds N.W. The expression of mRNAs for hepatocyte growth factor/scatter factor, its receptor c-met, and one of its activators tissue-type plasminogen activator show a systematic relationship in the developing and adult cerebral cortex and hippocampus. Brain Res. 1999, 821:356-367.
    • (1999) Brain Res. , vol.821 , pp. 356-367
    • Thewke, E.P.1    Seeds, N.W.2
  • 325
    • 77950350271 scopus 로고    scopus 로고
    • Memantine: a review of studies into its safety and efficacy in treating Alzheimer's disease and other dementias
    • Thomas S.J., Grossberg G.T. Memantine: a review of studies into its safety and efficacy in treating Alzheimer's disease and other dementias. Clin. Interv. Aging 2009, 4:367-377.
    • (2009) Clin. Interv. Aging , vol.4 , pp. 367-377
    • Thomas, S.J.1    Grossberg, G.T.2
  • 326
    • 0037409311 scopus 로고    scopus 로고
    • Molecules in focus. Angiotensin receptors: form and function and distribution
    • Thomas W.G., Mendelsohn F.A. Molecules in focus. Angiotensin receptors: form and function and distribution. Int. J. Biochem. Cell Biol. 2003, 35:774-779.
    • (2003) Int. J. Biochem. Cell Biol. , vol.35 , pp. 774-779
    • Thomas, W.G.1    Mendelsohn, F.A.2
  • 327
    • 9144237556 scopus 로고    scopus 로고
    • HGF promotes survival and growth of maturing sympathetic neurons by PI-3 kinase- and MAP kinase-dependent mechanisms
    • Thompson J., Dolcet X., Hilton M., Tolcos M., Davies A.M. HGF promotes survival and growth of maturing sympathetic neurons by PI-3 kinase- and MAP kinase-dependent mechanisms. Mol. Cell. Neurosci. 2004, 27:441-452.
    • (2004) Mol. Cell. Neurosci. , vol.27 , pp. 441-452
    • Thompson, J.1    Dolcet, X.2    Hilton, M.3    Tolcos, M.4    Davies, A.M.5
  • 328
    • 0022645133 scopus 로고
    • Enalapril. A review of its pharmacodynamics and pharmacokinetic properties, and therapeutic use in hypertension and congestive heart failure
    • Todd P.A., Heel R.C. Enalapril. A review of its pharmacodynamics and pharmacokinetic properties, and therapeutic use in hypertension and congestive heart failure. Drugs 1986, 31:198-248.
    • (1986) Drugs , vol.31 , pp. 198-248
    • Todd, P.A.1    Heel, R.C.2
  • 329
    • 0028982163 scopus 로고
    • Rapid appearance of beta-amyloid precursor protein immunoreactivity in glial cells following excitotoxic brain injury
    • Topper R., Gehrmann J., Banati R., Schwartz M., Block F., Noth J., Kreutzberg G.W. Rapid appearance of beta-amyloid precursor protein immunoreactivity in glial cells following excitotoxic brain injury. Acta Neuropathol. 1995, 89:23-28.
    • (1995) Acta Neuropathol. , vol.89 , pp. 23-28
    • Topper, R.1    Gehrmann, J.2    Banati, R.3    Schwartz, M.4    Block, F.5    Noth, J.6    Kreutzberg, G.W.7
  • 330
    • 84876423344 scopus 로고    scopus 로고
    • Effect of angiotensin II on spatial memory, cerebral blood flow, cholinergic neurotransmission, and brain derived neurotrophic factor in rats
    • Tota S., Goel R., Pachauri S.D., Rajasekar N., Najmi A.K., Hanif K., Nath C. Effect of angiotensin II on spatial memory, cerebral blood flow, cholinergic neurotransmission, and brain derived neurotrophic factor in rats. Psychopharmacology (Berl.) 2013, 226:357-369.
    • (2013) Psychopharmacology (Berl.) , vol.226 , pp. 357-369
    • Tota, S.1    Goel, R.2    Pachauri, S.D.3    Rajasekar, N.4    Najmi, A.K.5    Hanif, K.6    Nath, C.7
  • 331
    • 0037076798 scopus 로고    scopus 로고
    • Expression of a functionally active gp91 phox-containing neurtrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II
    • Touyz R.M., Chen X., Tabet F., Yao G., He G., Quinn M.T., Pagano P.J., Schiffrin E.L. Expression of a functionally active gp91 phox-containing neurtrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II. Circ. Res. 2002, 90:1205-1213.
    • (2002) Circ. Res. , vol.90 , pp. 1205-1213
    • Touyz, R.M.1    Chen, X.2    Tabet, F.3    Yao, G.4    He, G.5    Quinn, M.T.6    Pagano, P.J.7    Schiffrin, E.L.8
  • 332
    • 33745570098 scopus 로고    scopus 로고
    • The study on cognition and prognosis in the elderly (SCOPE) - recent analyses
    • Trenkwalder P. The study on cognition and prognosis in the elderly (SCOPE) - recent analyses. J. Hypertens. 2006, 24:S107-S114.
    • (2006) J. Hypertens. , vol.24 , pp. S107-S114
    • Trenkwalder, P.1
  • 334
    • 0034967770 scopus 로고    scopus 로고
    • Hepatocyte growth factor reduces the infarct volume after transient focal cerebral ischemia in rats
    • Tsuzuki N., Miyazawa T., Matsumoto K., Nakamura T., Shima K. Hepatocyte growth factor reduces the infarct volume after transient focal cerebral ischemia in rats. Neurol. Res. 2001, 23:417-424.
    • (2001) Neurol. Res. , vol.23 , pp. 417-424
    • Tsuzuki, N.1    Miyazawa, T.2    Matsumoto, K.3    Nakamura, T.4    Shima, K.5
  • 335
    • 79952157789 scopus 로고    scopus 로고
    • The endotoxin-induced neuroinflammation model of Parkinson's disease
    • ID 487450
    • Tufekci K.U., Genc S., Genc K. The endotoxin-induced neuroinflammation model of Parkinson's disease. Parkinson's Dis. 2011, ID 487450.
    • (2011) Parkinson's Dis.
    • Tufekci, K.U.1    Genc, S.2    Genc, K.3
  • 336
    • 39449117410 scopus 로고    scopus 로고
    • The shadow of death on the MET tyrosine kinase receptor
    • Tulasne D., Foveau B. The shadow of death on the MET tyrosine kinase receptor. Cell Death Diff. 2008, 15:427-434.
    • (2008) Cell Death Diff. , vol.15 , pp. 427-434
    • Tulasne, D.1    Foveau, B.2
  • 337
    • 34547617175 scopus 로고    scopus 로고
    • Hepatocyte growth factor-induced enhancement of dendritic branching is blocked by inhibitors of N-methyl-d-aspartate receptors and calcium/calmodulin-dependent kinases
    • Tyndall S.J., Patel S.J., Walikonis R.S. Hepatocyte growth factor-induced enhancement of dendritic branching is blocked by inhibitors of N-methyl-d-aspartate receptors and calcium/calmodulin-dependent kinases. J. Neurosci. Res. 2007, 85:2343-2351.
    • (2007) J. Neurosci. Res. , vol.85 , pp. 2343-2351
    • Tyndall, S.J.1    Patel, S.J.2    Walikonis, R.S.3
  • 338
    • 33746225421 scopus 로고    scopus 로고
    • The receptor tyrosine kinase Met and its ligand hepatocyte growth factor are clustered at excitatory synapses and can enhance clustering of synaptic proteins
    • Tyndall S.J., Walikonis R.S. The receptor tyrosine kinase Met and its ligand hepatocyte growth factor are clustered at excitatory synapses and can enhance clustering of synaptic proteins. Cell Cycle 2006, 5:1560-1568.
    • (2006) Cell Cycle , vol.5 , pp. 1560-1568
    • Tyndall, S.J.1    Walikonis, R.S.2
  • 339
    • 33846986360 scopus 로고    scopus 로고
    • Signaling by hepatocyte growth factor in neurons is induced by pharmacological stimulation of synaptic activity
    • Tyndall S.J., Walikonis R.S. Signaling by hepatocyte growth factor in neurons is induced by pharmacological stimulation of synaptic activity. Synapse 2007, 61:199-204.
    • (2007) Synapse , vol.61 , pp. 199-204
    • Tyndall, S.J.1    Walikonis, R.S.2
  • 340
    • 0032533765 scopus 로고    scopus 로고
    • Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0A resolution
    • Ultsch M., Lokker N.A., Godowski P.J., de Vos A.M. Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0A resolution. Structure 1999, 6:1383-1393.
    • (1999) Structure , vol.6 , pp. 1383-1393
    • Ultsch, M.1    Lokker, N.A.2    Godowski, P.J.3    de Vos, A.M.4
  • 342
    • 0032477844 scopus 로고    scopus 로고
    • Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis
    • Van Belle E., Witzenbichler B., Chen D., Silver M., Chang L., Schwall R., Isner J.M. Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis. Circulation 1998, 97:381-390.
    • (1998) Circulation , vol.97 , pp. 381-390
    • Van Belle, E.1    Witzenbichler, B.2    Chen, D.3    Silver, M.4    Chang, L.5    Schwall, R.6    Isner, J.M.7
  • 343
    • 62949248271 scopus 로고    scopus 로고
    • From angiotensin IV binding site to AT4 receptor
    • Vanderheyden P.M. From angiotensin IV binding site to AT4 receptor. Mol. Cell. Endocrinol. 2009, 302:159-166.
    • (2009) Mol. Cell. Endocrinol. , vol.302 , pp. 159-166
    • Vanderheyden, P.M.1
  • 344
    • 0036154210 scopus 로고    scopus 로고
    • Angiotensin and vascular fibrinolytic balance
    • Vaughan D.E. Angiotensin and vascular fibrinolytic balance. Am. J. Hypertens. 2002, 15(1 Pt2):3S-8S.
    • (2002) Am. J. Hypertens. , vol.15 , Issue.1 , pp. 3S-8S
    • Vaughan, D.E.1
  • 346
    • 81355139581 scopus 로고    scopus 로고
    • Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration
    • Villar-Cheda B., Valenzuela R., Rodriguez-Perez A.I., Guerra M.J., Labandeira-Garcia J.L. Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration. Neurobiol. Aging 2012, 33(204):e1-e11.
    • (2012) Neurobiol. Aging , vol.33 , Issue.204 , pp. e1-e11
    • Villar-Cheda, B.1    Valenzuela, R.2    Rodriguez-Perez, A.I.3    Guerra, M.J.4    Labandeira-Garcia, J.L.5
  • 347
    • 0037216357 scopus 로고    scopus 로고
    • Angiotensin IV in the central nervous system
    • von Bohlen und Halbach O. Angiotensin IV in the central nervous system. Cell Tissue Res. 2003, 31:1-9.
    • (2003) Cell Tissue Res. , vol.31 , pp. 1-9
    • von Bohlenund Halbach, O.1
  • 349
    • 79960905269 scopus 로고    scopus 로고
    • Hepatocyte growth factor acts as a mitogen and chemoattractant for postnatal subventricular zone-olfactory bulb neurogenesis
    • Wang T.W., Zhang H., Gyetko M.R., Parent J.M. Hepatocyte growth factor acts as a mitogen and chemoattractant for postnatal subventricular zone-olfactory bulb neurogenesis. Mol. Cell. Neurosci. 2011, 48:38-50.
    • (2011) Mol. Cell. Neurosci. , vol.48 , pp. 38-50
    • Wang, T.W.1    Zhang, H.2    Gyetko, M.R.3    Parent, J.M.4
  • 352
    • 0025119463 scopus 로고
    • Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells
    • Weidner K.M., Behrens J., Vandekerckhove J., Birchmeier W. Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J. Cell Biol. 1990, 111:2097-2108.
    • (1990) J. Cell Biol. , vol.111 , pp. 2097-2108
    • Weidner, K.M.1    Behrens, J.2    Vandekerckhove, J.3    Birchmeier, W.4
  • 353
    • 0029855280 scopus 로고    scopus 로고
    • Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis
    • Weidner K.M., Di Cesare S., Sachs M., Brinkmann V., Behrens J., Birchmeier W. Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis. Nature 1996, 384:173-176.
    • (1996) Nature , vol.384 , pp. 173-176
    • Weidner, K.M.1    Di Cesare, S.2    Sachs, M.3    Brinkmann, V.4    Behrens, J.5    Birchmeier, W.6
  • 354
    • 84861044859 scopus 로고    scopus 로고
    • Genetic rat models of Parkinson's disease
    • article ID 128356, 6 pages
    • Welchko R.M., Leveque X.T., Dunbar G.I. Genetic rat models of Parkinson's disease. Parkinson's Dis. 2012, article ID 128356, 6 pages.
    • (2012) Parkinson's Dis.
    • Welchko, R.M.1    Leveque, X.T.2    Dunbar, G.I.3
  • 356
    • 79953239152 scopus 로고    scopus 로고
    • Effects of the angiotensin receptor blocker azilsartan medoxomil versus olmesartan and valsartan on ambulatory and clinic blood pressure in patients with stages 1 and 2 hypertension
    • White W.B., Weber M.A., Sica D., Bakris G.L., Perez A., Cao C., Kupfer S. Effects of the angiotensin receptor blocker azilsartan medoxomil versus olmesartan and valsartan on ambulatory and clinic blood pressure in patients with stages 1 and 2 hypertension. Hypertension 2011, 57:413-420.
    • (2011) Hypertension , vol.57 , pp. 413-420
    • White, W.B.1    Weber, M.A.2    Sica, D.3    Bakris, G.L.4    Perez, A.5    Cao, C.6    Kupfer, S.7
  • 357
    • 0000358425 scopus 로고
    • Glutamyl aminopeptidase (aminopeptidase A), the BP-1/6C3 antigen
    • Wilk S., Healy D.P. Glutamyl aminopeptidase (aminopeptidase A), the BP-1/6C3 antigen. Adv. Neuroimmunol. 1993, 3:195-207.
    • (1993) Adv. Neuroimmunol. , vol.3 , pp. 195-207
    • Wilk, S.1    Healy, D.P.2
  • 358
    • 77955385260 scopus 로고    scopus 로고
    • Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration?
    • Witte M.E., Geurts J.G., deVries H.E., van der Valk P., van Horssen J. Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration?. Mitochondrion 2010, 10:411-418.
    • (2010) Mitochondrion , vol.10 , pp. 411-418
    • Witte, M.E.1    Geurts, J.G.2    deVries, H.E.3    van der Valk, P.4    van Horssen, J.5
  • 359
    • 0031591786 scopus 로고    scopus 로고
    • Important roles for angiotensin III and IV in the brain renin-angiotensin system
    • Wright J.W., Harding J.W. Important roles for angiotensin III and IV in the brain renin-angiotensin system. Brain Res. Rev. 1997, 25:96-124.
    • (1997) Brain Res. Rev. , vol.25 , pp. 96-124
    • Wright, J.W.1    Harding, J.W.2
  • 360
    • 2342655011 scopus 로고    scopus 로고
    • The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory
    • Wright J.W., Harding J.W. The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory. Prog. Neurobiol. 2004, 72:263-293.
    • (2004) Prog. Neurobiol. , vol.72 , pp. 263-293
    • Wright, J.W.1    Harding, J.W.2
  • 361
    • 66149108067 scopus 로고    scopus 로고
    • 4 receptor subtype as a target for the treatment of memory dysfunction associated with Alzheimer's disease
    • 4 receptor subtype as a target for the treatment of memory dysfunction associated with Alzheimer's disease. J. Renin Angiotensin Aldosterone Syst. 2008, 9:226-237.
    • (2008) J. Renin Angiotensin Aldosterone Syst. , vol.9 , pp. 226-237
    • Wright, J.W.1    Harding, J.W.2
  • 362
    • 70649099207 scopus 로고    scopus 로고
    • 4 receptor system as a new target for the treatment of Alzheimer's disease
    • 4 receptor system as a new target for the treatment of Alzheimer's disease. Drug Dev. Res. 2009, 70:472-480.
    • (2009) Drug Dev. Res. , vol.70 , pp. 472-480
    • Wright, J.W.1    Harding, J.W.2
  • 363
    • 79960675107 scopus 로고    scopus 로고
    • Brain renin-angiotensin: a new look at an old system
    • Wright J.W., Harding J.W. Brain renin-angiotensin: a new look at an old system. Prog. Neurobiol. 2011, 95:49-67.
    • (2011) Prog. Neurobiol. , vol.95 , pp. 49-67
    • Wright, J.W.1    Harding, J.W.2
  • 364
    • 84870198555 scopus 로고    scopus 로고
    • Importance of the brain angiotensin system in Parkinson's disease
    • article ID 860923
    • Wright J.W., Harding J.W. Importance of the brain angiotensin system in Parkinson's disease. Parkinson's Dis. 2012, 2012. article ID 860923.
    • (2012) Parkinson's Dis. , vol.2012
    • Wright, J.W.1    Harding, J.W.2
  • 367
    • 84905369537 scopus 로고    scopus 로고
    • A role for the brain RAS in Alzheimer's and Parkinson's diseases
    • article 158
    • Wright J.W., Kawas L.H., Harding J.W. A role for the brain RAS in Alzheimer's and Parkinson's diseases. Front. Endocrinol. 2013, 4. article 158.
    • (2013) Front. Endocrinol. , vol.4
    • Wright, J.W.1    Kawas, L.H.2    Harding, J.W.3
  • 368
    • 12444263415 scopus 로고    scopus 로고
    • Ethanol-induced suppression of LTP can be attenuated with an angiotensin IV analog
    • Wright J.W., Kramár E.A., Myers E.D., Davis C.J., Harding J.W. Ethanol-induced suppression of LTP can be attenuated with an angiotensin IV analog. Regul. Pept. 2003, 113:49-56.
    • (2003) Regul. Pept. , vol.113 , pp. 49-56
    • Wright, J.W.1    Kramár, E.A.2    Myers, E.D.3    Davis, C.J.4    Harding, J.W.5
  • 372
    • 39049161519 scopus 로고    scopus 로고
    • Angiotensin receptor subtype mediated physiologies and behaviors: new discoveries and clinical targets
    • Wright J.W., Yamamoto B.J., Harding J.W. Angiotensin receptor subtype mediated physiologies and behaviors: new discoveries and clinical targets. Prog. Neurobiol. 2008, 84:157-181.
    • (2008) Prog. Neurobiol. , vol.84 , pp. 157-181
    • Wright, J.W.1    Yamamoto, B.J.2    Harding, J.W.3
  • 373
    • 0036522967 scopus 로고    scopus 로고
    • Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
    • Wu D.C., Jackson-Lewis V., Vila M., Tieu K., Teismann P., Vadseth C., Choi D.K., Ischiropoulos H., Przedborski S. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J. Neurosci. 2002, 22:1763-1771.
    • (2002) J. Neurosci. , vol.22 , pp. 1763-1771
    • Wu, D.C.1    Jackson-Lewis, V.2    Vila, M.3    Tieu, K.4    Teismann, P.5    Vadseth, C.6    Choi, D.K.7    Ischiropoulos, H.8    Przedborski, S.9
  • 374
    • 0035793091 scopus 로고    scopus 로고
    • Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways
    • Xiao G.H., Jeffers M., Bellacosa A., Mitsuuchi Y., Vande Woude G.F., Testa J.R. Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:247-252.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 247-252
    • Xiao, G.H.1    Jeffers, M.2    Bellacosa, A.3    Mitsuuchi, Y.4    Vande Woude, G.F.5    Testa, J.R.6
  • 375
    • 34250186410 scopus 로고    scopus 로고
    • Cross talk between c-Met and epidermal growth factor receptor during retinal pigment epithelial wound healing
    • Xu K.P., Yu F.S. Cross talk between c-Met and epidermal growth factor receptor during retinal pigment epithelial wound healing. Invest. Ophthalmol. Vis. Sci. 2007, 48:2242-2248.
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48 , pp. 2242-2248
    • Xu, K.P.1    Yu, F.S.2
  • 377
    • 0028079544 scopus 로고
    • Immunohistochemistry with antibodies to hepatocyte growth factor and its receptor protein (c-MET) in human brain tissues
    • Yamada T., Tsubouchi H., Daikuhara Y., Prat M., Comoglio P.M., McGeer P.L., McGeer E.G. Immunohistochemistry with antibodies to hepatocyte growth factor and its receptor protein (c-MET) in human brain tissues. Brain Res. 1994, 637:308-312.
    • (1994) Brain Res. , vol.637 , pp. 308-312
    • Yamada, T.1    Tsubouchi, H.2    Daikuhara, Y.3    Prat, M.4    Comoglio, P.M.5    McGeer, P.L.6    McGeer, E.G.7
  • 380
    • 0037312985 scopus 로고    scopus 로고
    • Neutralization of hepatocyte growth factor leads to retarded cutaneous wound healing associated with decreased neovascularization and granulation tissue formation
    • Yoshida S., Ymaguchi Y., Ltami S., Yoshikawa K., Tabata Y., Matsumoto K., Nakamura T. Neutralization of hepatocyte growth factor leads to retarded cutaneous wound healing associated with decreased neovascularization and granulation tissue formation. J. Invest. Dermatol. 2003, 120:335-343.
    • (2003) J. Invest. Dermatol. , vol.120 , pp. 335-343
    • Yoshida, S.1    Ymaguchi, Y.2    Ltami, S.3    Yoshikawa, K.4    Tabata, Y.5    Matsumoto, K.6    Nakamura, T.7
  • 382
    • 33745075280 scopus 로고    scopus 로고
    • Findings and implications of the study on cognition and prognosis in the elderly (SCOPE) - a review
    • Zanchetti A., Elmfeldt D. Findings and implications of the study on cognition and prognosis in the elderly (SCOPE) - a review. Blood Press. 2006, 15:71-79.
    • (2006) Blood Press. , vol.15 , pp. 71-79
    • Zanchetti, A.1    Elmfeldt, D.2
  • 383
    • 80053479099 scopus 로고    scopus 로고
    • Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade
    • Zawada W.M., Banninger B.P., Thornton J., Marriott B., Cantu D., Rachubinski A.L., Das M., Griffin W.S., Jones S.M. Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade. J. Neuroinflamm. 2011, 8(129.e.):1-13.
    • (2011) J. Neuroinflamm. , vol.8 , Issue.129 e , pp. 1-13
    • Zawada, W.M.1    Banninger, B.P.2    Thornton, J.3    Marriott, B.4    Cantu, D.5    Rachubinski, A.L.6    Das, M.7    Griffin, W.S.8    Jones, S.M.9
  • 384
    • 0037096251 scopus 로고    scopus 로고
    • A novel function of monomeric amyloid beta-protein serving as an antioxidant molecule against metal-induced oxidative damage
    • Zou K., Gong J.S., Yanagisawa K., Michikawa M. A novel function of monomeric amyloid beta-protein serving as an antioxidant molecule against metal-induced oxidative damage. J. Neurosci. 2002, 22:4833-4841.
    • (2002) J. Neurosci. , vol.22 , pp. 4833-4841
    • Zou, K.1    Gong, J.S.2    Yanagisawa, K.3    Michikawa, M.4
  • 386
    • 70450257558 scopus 로고    scopus 로고
    • Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme
    • Zou K., Maeda T., Watanabe A., Liu J., Liu S., Oba R., Satoh Y., Komano H., Michikawa M. Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme. J. Biol. Chem. 2009, 284:31914-31920.
    • (2009) J. Biol. Chem. , vol.284 , pp. 31914-31920
    • Zou, K.1    Maeda, T.2    Watanabe, A.3    Liu, J.4    Liu, S.5    Oba, R.6    Satoh, Y.7    Komano, H.8    Michikawa, M.9


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