Geniposide inhibits interleukin-6 and interleukin-8 production in lipopolysaccharide-induced human umbilical vein endothelial cells by blocking p38 and ERK1/2 signaling pathways

Inflammation Research

Volumn 59, Issue 6, 2010, Pages 451-461

  Liu, Hong Tao ^a,b   He, Jun Lin ^a   Li, Wen Ming ^a   Yang, Zhu ^a   Wang, Ying Xiong ^a   Yin, Juan ^a   Du, Yu Guang ^b   Yu, Chao ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

Author keywords

Chemokines; Endothelial cells; Inflammation; LPS

Indexed keywords

GENIPOSIDE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; SYNAPTOPHYSIN;

ARTICLE; CELL ADHESION; CELL MIGRATION; CELL STRAIN U937; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MONOCYTE; MONOLAYER CULTURE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UMBILICAL VEIN; WESTERN BLOTTING; WOUND HEALING;

BLOTTING, WESTERN; CELL ADHESION; CELL MOVEMENT; CELL SURVIVAL; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; I-KAPPA B PROTEINS; INDICATORS AND REAGENTS; INTERLEUKIN-6; INTERLEUKIN-8; IRIDOIDS; LIPOPOLYSACCHARIDES; MONOCYTES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; U937 CELLS; UMBILICAL VEINS; WOUND HEALING;

EID: 77953324904     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-009-0118-3     Document Type: Article

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