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Volumn 28, Issue 3, 2015, Pages 721-741

Diversity and evolution in the genome of clostridium difficile

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL TRANSMISSION; BACTERIOPHAGE; GENETIC RECOMBINATION; GENOME ANALYSIS; HUMAN; MICROBIAL DIVERSITY; MOLECULAR CLOCK; MOLECULAR EVOLUTION; MOLECULAR PHYLOGENY; NONHUMAN; PEPTOCLOSTRIDIUM DIFFICILE; POINT MUTATION; POLYMERASE CHAIN REACTION; RIBOTYPING; TAXONOMY; BACTERIAL GENOME; CLASSIFICATION; CLOSTRIDIUM INFECTION; GENETIC VARIABILITY; GENETICS; MICROBIOLOGY; PATHOGENICITY; PHYLOGENY;

EID: 84933505084     PISSN: 08938512     EISSN: 10986618     Source Type: Journal    
DOI: 10.1128/CMR.00127-14     Document Type: Article
Times cited : (208)

References (208)
  • 1
    • 67649391053 scopus 로고    scopus 로고
    • Clostridium difficile
    • Rupnik M, Wilcox MH, Gerding DN. 2009. Clostridium difficile infection: new developments in epidemiology and pathogenesis. Nat Rev Microbiol 7:526–536. http://dx.doi.org/10.1038/nrmicro2164.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 526-536
    • Rupnik, M.1    Wilcox, M.H.2    Gerding, D.N.3
  • 2
    • 84860348952 scopus 로고    scopus 로고
    • Clinical and economic burden of Clostridium difficile infection in Europe: A systematic review of healthcare-facility-acquired infection
    • Wiegand PN, Nathwani D, Wilcox MH, Stephens J, Shelbaya A, Haider S. 2012. Clinical and economic burden of Clostridium difficile infection in Europe: a systematic review of healthcare-facility-acquired infection. J Hosp Infect 81:1–14. http://dx.doi.org/10.1016/j.jhin.2012.02.004.
    • (2012) J Hosp Infect , vol.81 , pp. 1-14
    • Wiegand, P.N.1    Nathwani, D.2    Wilcox, M.H.3    Stephens, J.4    Shelbaya, A.5    Haider, S.6
  • 3
    • 84884597711 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention, Atlanta, GA
    • Centers for Disease Control and Prevention. 2013. Antibiotic resistance threats in the United States, 2013. Centers for Disease Control and Prevention, Atlanta, GA. http://www.cdc.gov/drugresistance/threat-report-2013/.
    • (2013) Antibiotic Resistance Threats in the United States, 2013
  • 5
    • 0000795948 scopus 로고
    • Intestinal flora in newborn infants with a description of a new pathogenic anaerobe, Bacillus difficilis
    • Hall IC, O’Toole E. 1935. Intestinal flora in newborn infants with a description of a new pathogenic anaerobe, Bacillus difficilis. Am J Dis Child 49: 390–402. http://dx.doi.org/10.1001/archpedi.1935.01970020105010.
    • (1935) Am J Dis Child , vol.49 , pp. 390-402
    • Hall, I.C.1    O’Toole, E.2
  • 6
    • 0005748691 scopus 로고
    • Further studies on Bacillus difficilis (Hall and O’Toole)
    • Snyder ML. 1937. Further studies on Bacillus difficilis (Hall and O’Toole). J Infect Dis 60:223–231. http://dx.doi.org/10.1093/infdis/60.2.223.
    • (1937) J Infect Dis , vol.60 , pp. 223-231
    • Snyder, M.L.1
  • 7
    • 0018075343 scopus 로고
    • Role of Clostridium difficile in antibiotic-associated pseudomembranous colitis
    • Bartlett JG, Moon N, Chang TW, Taylor N, Onderdonk AB. 1978. Role of Clostridium difficile in antibiotic-associated pseudomembranous colitis. Gastroenterology 75:778–782.
    • (1978) Gastroenterology , vol.75 , pp. 778-782
    • Bartlett, J.G.1    Moon, N.2    Chang, T.W.3    Taylor, N.4    Onderdonk, A.B.5
  • 8
    • 77956871102 scopus 로고    scopus 로고
    • Clostridium difficile
    • Heinlen L, Ballard JD. 2010. Clostridium difficile infection. AmJ Med Sci 340:247–252. http://dx.doi.org/10.1097/MAJ.0b013e3181e939d8.
    • (2010) Amj Med Sci , vol.340 , pp. 247-252
    • Heinlen, L.1    Ballard, J.D.2
  • 9
    • 0021952214 scopus 로고
    • Clinical and endoscopic findings in patients early in the course of Clostridium difficile-associated pseudomembranous colitis
    • Gebhard RL, Gerding DN, Olson MM, Peterson LR, McClain CJ, Ansel HJ, Shaw MJ, Schwartz ML. 1985. Clinical and endoscopic findings in patients early in the course of Clostridium difficile-associated pseudomembranous colitis. Am J Med 78:45–48. http://dx.doi.org/10.1016/0002-9343(85)90460-7.
    • (1985) Am J Med , vol.78 , pp. 45-48
    • Gebhard, R.L.1    Gerding, D.N.2    Olson, M.M.3    Peterson, L.R.4    McClain, C.J.5    Ansel, H.J.6    Shaw, M.J.7    Schwartz, M.L.8
  • 10
    • 84913554623 scopus 로고    scopus 로고
    • Extraintestinal Clostridium difficile infections: A single-center experience
    • Gupta A, Patel R, Baddour LM, Pardi DS, Khanna S. 2014. Extraintestinal Clostridium difficile infections: a single-center experience. Mayo Clin Proc 89:1525–1536. http://dx.doi.org/10.1016/j.mayocp.2014.07.012.
    • (2014) Mayo Clin Proc , vol.89 , pp. 1525-1536
    • Gupta, A.1    Patel, R.2    Baddour, L.M.3    Pardi, D.S.4    Khanna, S.5
  • 12
    • 0031752883 scopus 로고    scopus 로고
    • Risk factors for Clostridium difficile infection
    • Bignardi GE. 1998. Risk factors for Clostridium difficile infection. J Hosp Infect 40:1–15. http://dx.doi.org/10.1016/S0195-6701(98)90019-6.
    • (1998) J Hosp Infect , vol.40 , pp. 1-15
    • Bignardi, G.E.1
  • 13
    • 77958175876 scopus 로고    scopus 로고
    • Clostridium difficile
    • Chopra T, Alangaden GJ, Chandrasekar P. 2010. Clostridium difficile infection in cancer patients and hematopoietic stem cell transplant recipients. Expert Rev Anti Infect Ther 8:1113–1119. http://dx.doi.org/10.1586/eri.10.95.
    • (2010) Expert Rev Anti Infect Ther , vol.8 , pp. 1113-1119
    • Chopra, T.1    Alangaden, G.J.2    Chandrasekar, P.3
  • 14
    • 0033839497 scopus 로고    scopus 로고
    • The fluoroquinolone antibacterials: Past, present and future perspectives
    • Appelbaum PC, Hunter PA. 2000. The fluoroquinolone antibacterials: past, present and future perspectives. Int J Antimicrob Agents 16:5–15. http://dx.doi.org/10.1016/S0924-8579(00)00192-8.
    • (2000) Int J Antimicrob Agents , vol.16 , pp. 5-15
    • Appelbaum, P.C.1    Hunter, P.A.2
  • 15
    • 33847618667 scopus 로고    scopus 로고
    • Narrative review: The new epidemic of Clostridium difficile-associated enteric disease
    • Bartlett JG. 2006. Narrative review: the new epidemic of Clostridium difficile-associated enteric disease. Ann Intern Med 145:758–764. http://dx.doi.org/10.7326/0003-4819-145-10-200611210-00008.
    • (2006) Ann Intern Med , vol.145 , pp. 758-764
    • Bartlett, J.G.1
  • 16
    • 84869169946 scopus 로고    scopus 로고
    • Efficacy of different cleaning and disinfection methods against Clostridium difficile spores: Importance of physical removal versus sporicidal inactivation
    • Rutala WA, Gergen MF, Weber DJ. 2012. Efficacy of different cleaning and disinfection methods against Clostridium difficile spores: importance of physical removal versus sporicidal inactivation. Infect Control Hosp Epidemiol 33:1255–1258. http://dx.doi.org/10.1086/668434.
    • (2012) Infect Control Hosp Epidemiol , vol.33 , pp. 1255-1258
    • Rutala, W.A.1    Gergen, M.F.2    Weber, D.J.3
  • 17
    • 39749111479 scopus 로고    scopus 로고
    • Measures to control and prevent Clostridium difficile infection
    • Gerding DN, Muto CA, Owens RC, Jr. 2008. Measures to control and prevent Clostridium difficile infection. Clin Infect Dis 46(Suppl 1):S43–S49. http://dx.doi.org/10.1086/521861.
    • (2008) Clin Infect Dis , vol.46 , pp. S43-S49
    • Gerding, D.N.1    Muto, C.A.2    Owens, R.C.3
  • 18
    • 0019497353 scopus 로고
    • Isolation of Clostridium difficile from the environment and contacts of patients with antibiotic-associated colitis
    • Kim KH, Fekety R, Batts DH, Brown D, Cudmore M, Silva J, Jr, Waters D. 1981. Isolation of Clostridium difficile from the environment and contacts of patients with antibiotic-associated colitis. J Infect Dis 143:42–50. http://dx.doi.org/10.1093/infdis/143.1.42.
    • (1981) J Infect Dis , vol.143 , pp. 42-50
    • Kim, K.H.1    Fekety, R.2    Batts, D.H.3    Brown, D.4    Cudmore, M.5    Silva, J.6    Waters, D.7
  • 20
    • 84887259304 scopus 로고    scopus 로고
    • European Society of Clinical Microbiology and Infectious Diseases: Update of the treatment guidance document for Clostridium difficile infection
    • Debast SB, Bauer MP, Kuijper EJ. 2014. European Society of Clinical Microbiology and Infectious Diseases: update of the treatment guidance document for Clostridium difficile infection. Clin Microbiol Infect 20(Suppl 2):1–26. http://dx.doi.org/10.1111/1469-0691.12418.
    • (2014) Clin Microbiol Infect , vol.20 , pp. 1-26
    • Debast, S.B.1    Bauer, M.P.2    Kuijper, E.J.3
  • 22
    • 84899684470 scopus 로고    scopus 로고
    • Clokie MR. 2014. Clostridium difficile phages: Still difficult?
    • Hargreaves KR, Clokie MR. 2014. Clostridium difficile phages: still difficult? Front Microbiol 5:184. http://dx.doi.org/10.3389/fmicb.2014.00184.
    • Front Microbiol , vol.5
    • Hargreaves, K.R.1
  • 23
    • 84860605588 scopus 로고    scopus 로고
    • Clostridium difficile
    • Gerding DN. 2012. Clostridium difficile infection prevention: biotherapeutics, immunologics, and vaccines. Discov Med 13:75–83.
    • (2012) Discov Med , vol.13 , pp. 75-83
    • Gerding, D.N.1
  • 24
    • 77951026738 scopus 로고    scopus 로고
    • Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)
    • Cohen SH, Gerding DN, Johnson S, Kelly CP, Loo VG, McDonald LC, Pepin J, Wilcox MH. 2010. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infect Control Hosp Epidemiol 31:431–455. http://dx.doi.org/10.1086/651706.
    • (2010) Infect Control Hosp Epidemiol , vol.31 , pp. 431-455
    • Cohen, S.H.1    Gerding, D.N.2    Johnson, S.3    Kelly, C.P.4    Loo, V.G.5    McDonald, L.C.6    Pepin, J.7    Wilcox, M.H.8
  • 25
    • 84857790535 scopus 로고    scopus 로고
    • Clostridium difficile
    • Shen A. 2012. Clostridium difficile toxins: mediators of inflammation. J Innate Immun 4:149–158. http://dx.doi.org/10.1159/000332946.
    • (2012) J Innate Immun , vol.4 , pp. 149-158
    • Shen, A.1
  • 26
    • 77957988127 scopus 로고    scopus 로고
    • The role of toxin A and toxin B in Clostridium difficile infection
    • Kuehne SA, Cartman ST, Heap JT, Kelly ML, Cockayne A, Minton NP. 2010. The role of toxin A and toxin B in Clostridium difficile infection. Nature 467:711–713. http://dx.doi.org/10.1038/nature09397.
    • (2010) Nature , vol.467 , pp. 711-713
    • Kuehne, S.A.1    Cartman, S.T.2    Heap, J.T.3    Kelly, M.L.4    Cockayne, A.5    Minton, N.P.6
  • 27
    • 17444366186 scopus 로고    scopus 로고
    • Clostridium difficile
    • Voth DE, Ballard JD. 2005. Clostridium difficile toxins: mechanism of action and role in disease. Clin Microbiol Rev 18:247–263. http://dx.doi.org/10.1128/CMR.18.2.247-263.2005.
    • (2005) Clin Microbiol Rev , vol.18 , pp. 247-263
    • Voth, D.E.1    Ballard, J.D.2
  • 29
    • 84937638188 scopus 로고    scopus 로고
    • The role of flagella in Clostridium difficile pathogenicity
    • Stevenson E, Minton NP, Kuehne SA. 2015. The role of flagella in Clostridium difficile pathogenicity. Trends Microbiol 23:275–282. http://dx.doi.org/10.1016/j.tim.2015.01.004.
    • (2015) Trends Microbiol , vol.23 , pp. 275-282
    • Stevenson, E.1    Minton, N.P.2    Kuehne, S.A.3
  • 30
    • 80054757852 scopus 로고    scopus 로고
    • Clostridium difficile isolates with increased sporulation: Emergence of PCR ribotype 002 in Hong Kong
    • Cheng V, Yam W, Lam O, Tsang J, Tse E, Siu G, Chan J, Tse H, To K, Tai J. 2011. Clostridium difficile isolates with increased sporulation: emergence of PCR ribotype 002 in Hong Kong. Eur J Clin Microbiol Infect Dis 30:1371–1381. http://dx.doi.org/10.1007/s10096-011-1231-0.
    • (2011) Eur J Clin Microbiol Infect Dis , vol.30 , pp. 1371-1381
    • Cheng, V.1    Yam, W.2    Lam, O.3    Tsang, J.4    Tse, E.5    Siu, G.6    Chan, J.7    Tse, H.8    To, K.9    Tai, J.10
  • 31
    • 78650828068 scopus 로고    scopus 로고
    • Reference assays for Clostridium difficile infection: One or two gold standards?
    • Planche T, Wilcox M. 2011. Reference assays for Clostridium difficile infection: one or two gold standards? J Clin Pathol 64:1–5. http://dx.doi.org/10.1136/jcp.2010.080135.
    • (2011) J Clin Pathol , vol.64 , pp. 1-5
    • Planche, T.1    Wilcox, M.2
  • 32
    • 75649148601 scopus 로고    scopus 로고
    • Evaluation of diagnostic tests for Clostridium difficile infection
    • Swindells J, Brenwald N, Reading N, Oppenheim B. 2010. Evaluation of diagnostic tests for Clostridium difficile infection. J Clin Microbiol 48:606–608. http://dx.doi.org/10.1128/JCM.01579-09.
    • (2010) J Clin Microbiol , vol.48 , pp. 606-608
    • Swindells, J.1    Brenwald, N.2    Reading, N.3    Oppenheim, B.4
  • 33
    • 84873808423 scopus 로고    scopus 로고
    • Current application and future perspectives of molecular typing methods to study Clostridium difficile infections
    • pii_20381
    • Knetsch CW, Lawley TD, Hensgens MP, Corver J, Wilcox MW, Kuijper EJ. 2013. Current application and future perspectives of molecular typing methods to study Clostridium difficile infections. Euro Surveill 18(4):pii_20381. http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId_20381.
    • (2013) Euro Surveill , vol.18 , Issue.4
    • Knetsch, C.W.1    Lawley, T.D.2    Hensgens, M.P.3    Corver, J.4    Wilcox, M.W.5    Kuijper, E.J.6
  • 34
    • 67849103660 scopus 로고    scopus 로고
    • Comparison of molecular typing methods applied to Clostridium difficile
    • Kuijper EJ, van den Berg RJ, Brazier JS. 2009. Comparison of molecular typing methods applied to Clostridium difficile. Methods Mol Biol 551:159–171. http://dx.doi.org/10.1007/978-1-60327-999-4_13.
    • (2009) Methods Mol Biol , vol.551 , pp. 159-171
    • Kuijper, E.J.1    Van Den Berg, R.J.2    Brazier, J.S.3
  • 35
    • 84888334705 scopus 로고    scopus 로고
    • Comparison of multilocus variable-number tandem-repeat analysis and whole-genome sequencing for investigation of Clostridium difficile transmission
    • Eyre DW, Fawley WN, Best EL, Griffiths D, Stoesser NE, Crook DW, Peto TE, Walker AS, Wilcox MH. 2013. Comparison of multilocus variable-number tandem-repeat analysis and whole-genome sequencing for investigation of Clostridium difficile transmission. J Clin Microbiol 51:4141–4149. http://dx.doi.org/10.1128/JCM.01095-13.
    • (2013) J Clin Microbiol , vol.51 , pp. 4141-4149
    • Eyre, D.W.1    Fawley, W.N.2    Best, E.L.3    Griffiths, D.4    Stoesser, N.E.5    Crook, D.W.6    Peto, T.E.7    Walker, A.S.8    Wilcox, M.H.9
  • 36
    • 84888330040 scopus 로고    scopus 로고
    • Clostridium difficile
    • Eyre DW, Walker AS. 2013. Clostridium difficile surveillance: harnessing new technologies to control transmission. Expert Rev Anti Infect Ther 11:1193–1205. http://dx.doi.org/10.1586/14787210.2013.845987.
    • (2013) Expert Rev Anti Infect Ther , vol.11 , pp. 1193-1205
    • Eyre, D.W.1    Walker, A.S.2
  • 37
    • 84865591918 scopus 로고    scopus 로고
    • The continually evolving Clostridium difficile species
    • Cairns MD, Stabler RA, Shetty N, Wren BW. 2012. The continually evolving Clostridium difficile species. Future Microbiol 7:945–957. http://dx.doi.org/10.2217/fmb.12.73.
    • (2012) Future Microbiol , vol.7 , pp. 945-957
    • Cairns, M.D.1    Stabler, R.A.2    Shetty, N.3    Wren, B.W.4
  • 38
    • 84930941085 scopus 로고    scopus 로고
    • Molecular methods for detecting and typing of Clostridium difficile
    • Collins DA, Elliott B, Riley TV. 2015. Molecular methods for detecting and typing of Clostridium difficile. Pathology 47:211–218. http://dx.doi.org/10.1097/PAT.0000000000000238.
    • (2015) Pathology , vol.47 , pp. 211-218
    • Collins, D.A.1    Elliott, B.2    Riley, T.V.3
  • 39
    • 0032901542 scopus 로고    scopus 로고
    • PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes
    • Stubbs SL, Brazier JS, O’Neill GL, Duerden BI. 1999. PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes. J Clin Microbiol 37:461–463.
    • (1999) J Clin Microbiol , vol.37 , pp. 461-463
    • Stubbs, S.L.1    Brazier, J.S.2    O’Neill, G.L.3    Duerden, B.I.4
  • 40
    • 84907225931 scopus 로고    scopus 로고
    • Recombination drives evolution of the Clostridium difficile 16S-23S rRNA intergenic spacer region
    • Janezic S, Indra A, Rattei T, Weinmaier T, Rupnik M. 2014. Recombination drives evolution of the Clostridium difficile 16S-23S rRNA intergenic spacer region. PLoS One 9:e106545. http://dx.doi.org/10.1371/journal.pone.0106545.
    • (2014) Plos One , vol.9
    • Janezic, S.1    Indra, A.2    Rattei, T.3    Weinmaier, T.4    Rupnik, M.5
  • 41
    • 42149172381 scopus 로고    scopus 로고
    • Heterogeneity of large clostridial toxins: Importance of Clostridium difficile toxinotypes
    • Rupnik M. 2008. Heterogeneity of large clostridial toxins: importance of Clostridium difficile toxinotypes. FEMS Microbiol Rev 32:541–555. http://dx.doi.org/10.1111/j.1574-6976.2008.00110.x.
    • (2008) FEMS Microbiol Rev , vol.32 , pp. 541-555
    • Rupnik, M.1
  • 42
    • 0031878772 scopus 로고    scopus 로고
    • A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates
    • Rupnik M, Avesani V, Janc M, von Eichel-Streiber C, Delmee M. 1998. A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates. J Clin Microbiol 36:2240–2247.
    • (1998) J Clin Microbiol , vol.36 , pp. 2240-2247
    • Rupnik, M.1    Avesani, V.2    Janc, M.3    Von Eichel-Streiber, C.4    Delmee, M.5
  • 43
    • 2942594170 scopus 로고    scopus 로고
    • Multilocus sequence typing analysis of human and animal Clostridium difficile isolates of various toxigenic types
    • Lemee L, Dhalluin A, Pestel-Caron M, Lemeland JF, Pons JL. 2004. Multilocus sequence typing analysis of human and animal Clostridium difficile isolates of various toxigenic types. J Clin Microbiol 42:2609–2617. http://dx.doi.org/10.1128/JCM.42.6.2609-2617.2004.
    • (2004) J Clin Microbiol , vol.42 , pp. 2609-2617
    • Lemee, L.1    Dhalluin, A.2    Pestel-Caron, M.3    Lemeland, J.F.4    Pons, J.L.5
  • 47
    • 84865086262 scopus 로고    scopus 로고
    • Comparative analysis of an expanded Clostridium difficile reference strain collection reveals genetic diversity and evolution through six lineages
    • Knetsch CW, Terveer EM, Lauber C, Gorbalenya AE, Harmanus C, Kuijper EJ, Corver J, van Leeuwen HC. 2012. Comparative analysis of an expanded Clostridium difficile reference strain collection reveals genetic diversity and evolution through six lineages. Infect Genet Evol 12: 1577–1585. http://dx.doi.org/10.1016/j.meegid.2012.06.003.
    • (2012) Infect Genet Evol , vol.12 , pp. 1577-1585
    • Knetsch, C.W.1    Terveer, E.M.2    Lauber, C.3    Gorbalenya, A.E.4    Harmanus, C.5    Kuijper, E.J.6    Corver, J.7    Van Leeuwen, H.C.8
  • 55
    • 84861206666 scopus 로고    scopus 로고
    • Draft genome sequence of the nontoxigenic Clostridium difficile strain CD37
    • Brouwer MS, Allan E, Mullany P, Roberts AP. 2012. Draft genome sequence of the nontoxigenic Clostridium difficile strain CD37. J Bacteriol 194:2125–2126. http://dx.doi.org/10.1128/JB.00122-12.
    • (2012) J Bacteriol , vol.194 , pp. 2125-2126
    • Brouwer, M.S.1    Allan, E.2    Mullany, P.3    Roberts, A.P.4
  • 59
    • 79960332015 scopus 로고    scopus 로고
    • In-depth genetic analysis of Clostridium difficile PCR-ribotype 027 strains reveals high genome fluidity including point mutations and inversions
    • Stabler RA, Valiente E, Dawson LF, He M, Parkhill J, Wren BW. 2010. In-depth genetic analysis of Clostridium difficile PCR-ribotype 027 strains reveals high genome fluidity including point mutations and inversions. Gut Microbes 1:269–276. http://dx.doi.org/10.4161/gmic.1.4.11870.
    • (2010) Gut Microbes , vol.1 , pp. 269-276
    • Stabler, R.A.1    Valiente, E.2    Dawson, L.F.3    He, M.4    Parkhill, J.5    Wren, B.W.6
  • 62
    • 84998910124 scopus 로고    scopus 로고
    • Draft genome sequence of Clostridium bifermentans strain WYM, a promising biohydrogen producer isolated from landfill leachate sludge
    • Wong YM, Juan JC, Gan HM, Austin CM. 2014. Draft genome sequence of Clostridium bifermentans strain WYM, a promising biohydrogen producer isolated from landfill leachate sludge. Genome Announc 2(2):e00077-14. http://dx.doi.org/10.1128/genomeA.00077-14.
    • (2014) Genome Announc , vol.2 , Issue.2
    • Wong, Y.M.1    Juan, J.C.2    Gan, H.M.3    Austin, C.M.4
  • 64
    • 0030605226 scopus 로고    scopus 로고
    • Definition of the single integration site of the pathogenicity locus in Clostridium difficile
    • Braun V, Hundsberger T, Leukel P, Sauerborn M, von Eichel-Streiber C. 1996. Definition of the single integration site of the pathogenicity locus in Clostridium difficile. Gene 181:29–38. http://dx.doi.org/10.1016/S0378-1119(96)00398-8.
    • (1996) Gene , vol.181 , pp. 29-38
    • Braun, V.1    Hundsberger, T.2    Leukel, P.3    Sauerborn, M.4    Von Eichel-Streiber, C.5
  • 65
    • 0025994934 scopus 로고
    • Nontoxigenic strains of Clostridium difficile lack the genes for both toxin A and toxin B
    • Fluit AC, Wolfhagen MJHM, Verdonk GPHT, Jansze M, Torensma R, Verhoef J. 1991. Nontoxigenic strains of Clostridium difficile lack the genes for both toxin A and toxin B. J Clin Microbiol 29:2666–2667.
    • (1991) J Clin Microbiol , vol.29 , pp. 2666-2667
    • Fluit, A.C.1    Wolfhagen, M.2    Verdonk, G.3    Jansze, M.4    Torensma, R.5    Verhoef, J.6
  • 66
    • 0035826910 scopus 로고    scopus 로고
    • Regulation of toxin synthesis in Clostridium difficile by an alternative RNA polymerase sigma factor
    • Mani N, Dupuy B. 2001. Regulation of toxin synthesis in Clostridium difficile by an alternative RNA polymerase sigma factor. Proc Natl Acad Sci U S A 98:5844–5849. http://dx.doi.org/10.1073/pnas.101126598.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5844-5849
    • Mani, N.1    Dupuy, B.2
  • 67
    • 0034960958 scopus 로고    scopus 로고
    • Evidence for holin function of tcdE gene in the pathogenicity of Clostridium difficile
    • Tan KS, Wee BY, Song KP. 2001. Evidence for holin function of tcdE gene in the pathogenicity of Clostridium difficile. J Med Microbiol 50: 613–619.
    • (2001) J Med Microbiol , vol.50 , pp. 613-619
    • Tan, K.S.1    Wee, B.Y.2    Song, K.P.3
  • 68
    • 34249782307 scopus 로고    scopus 로고
    • Clostridium difficile
    • Matamouros S, England P, Dupuy B. 2007. Clostridium difficile toxin expression is inhibited by the novel regulator TcdC. Mol Microbiol 64: 1274–1288. http://dx.doi.org/10.1111/j.1365-2958.2007.05739.x.
    • (2007) Mol Microbiol , vol.64 , pp. 1274-1288
    • Matamouros, S.1    England, P.2    Dupuy, B.3
  • 71
    • 84865074510 scopus 로고    scopus 로고
    • TcdC does not significantly repress toxin expression in Clostridium difficile 630 delta Erm
    • Bakker D, Smits WK, Kuijper EJ, Corver J. 2012. TcdC does not significantly repress toxin expression in Clostridium difficile 630 delta Erm. PLoS One 7:e43247. http://dx.doi.org/10.1371/journal.pone.0043247.
    • (2012) Plos One , vol.7
    • Bakker, D.1    Smits, W.K.2    Kuijper, E.J.3    Corver, J.4
  • 72
    • 84863792386 scopus 로고    scopus 로고
    • Precise manipulation of the Clostridium difficile chromosome reveals a lack of association between the tcdC genotype and toxin production
    • Cartman ST, Kelly ML, Heeg D, Heap JT, Minton NP. 2012. Precise manipulation of the Clostridium difficile chromosome reveals a lack of association between the tcdC genotype and toxin production. Appl Environ Microbiol 78:4683–4690. http://dx.doi.org/10.1128/AEM.00249-12.
    • (2012) Appl Environ Microbiol , vol.78 , pp. 4683-4690
    • Cartman, S.T.1    Kelly, M.L.2    Heeg, D.3    Heap, J.T.4    Minton, N.P.5
  • 73
    • 33749628473 scopus 로고    scopus 로고
    • Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains
    • Stabler RA, Gerding DN, Songer JG, Drudy D, Brazier JS, Trinh HT, Witney AA, Hinds J, Wren BW. 2006. Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains. J Bacteriol 188:7297–7305. http://dx.doi.org/10.1128/JB.00664-06.
    • (2006) J Bacteriol , vol.188 , pp. 7297-7305
    • Stabler, R.A.1    Gerding, D.N.2    Songer, J.G.3    Drudy, D.4    Brazier, J.S.5    Trinh, H.T.6    Witney, A.A.7    Hinds, J.8    Wren, B.W.9
  • 74
    • 84929485093 scopus 로고    scopus 로고
    • Toxin synthesis by Clostridium difficile is regulated through quorum signaling
    • Darkoh C, DuPont HL, Norris SJ, Kaplan HB. 2015. Toxin synthesis by Clostridium difficile is regulated through quorum signaling. mBio 6(2): e02569-14. http://dx.doi.org/10.1128/mBio.02569-14.
    • (2015) Mbio , vol.6 , Issue.2
    • Darkoh, C.1    Dupont, H.L.2    Norris, S.J.3    Kaplan, H.B.4
  • 77
    • 78650114015 scopus 로고    scopus 로고
    • Analysis of ultra low genome conservation in Clostridium difficile
    • Scaria J, Ponnala L, Janvilisri T, Yan W, Mueller LA, Chang YF. 2010. Analysis of ultra low genome conservation in Clostridium difficile. PLoS One 5:e15147. http://dx.doi.org/10.1371/journal.pone.0015147.
    • (2010) Plos One , vol.5
    • Scaria, J.1    Ponnala, L.2    Janvilisri, T.3    Yan, W.4    Mueller, L.A.5    Chang, Y.F.6
  • 78
    • 77950671568 scopus 로고    scopus 로고
    • Pan-genome analysis provides much higher strain typing resolution than multi-locus sequence typing
    • Hall BG, Ehrlich GD, Hu FZ. 2010. Pan-genome analysis provides much higher strain typing resolution than multi-locus sequence typing. Microbiology 156:1060–1068. http://dx.doi.org/10.1099/mic.0.035188-0.
    • (2010) Microbiology , vol.156 , pp. 1060-1068
    • Hall, B.G.1    Ehrlich, G.D.2    Hu, F.Z.3
  • 81
    • 84893721427 scopus 로고    scopus 로고
    • Comparative analysis of the full genome of the Helicobacter pylori isolate, Sahul64, identifies genes of high divergence
    • Lu W, Wise M, Tay C, Windsor H, Marshall B, Peacock C, Perkins T. 2014. Comparative analysis of the full genome of the Helicobacter pylori isolate, Sahul64, identifies genes of high divergence. J Bacteriol 196: 1073–1083. http://dx.doi.org/10.1128/JB.01021-13.
    • (2014) J Bacteriol , vol.196 , pp. 1073-1083
    • Lu, W.1    Wise, M.2    Tay, C.3    Windsor, H.4    Marshall, B.5    Peacock, C.6    Perkins, T.7
  • 84
    • 13844306368 scopus 로고    scopus 로고
    • Measuring genome conservation across taxa: Divided strains and united kingdoms
    • Kunin V, Ahren D, Goldovsky L, Janssen P, Ouzounis CA. 2005. Measuring genome conservation across taxa: divided strains and united kingdoms. Nucleic Acids Res 33:616–621. http://dx.doi.org/10.1093/nar/gki181.
    • (2005) Nucleic Acids Res , vol.33 , pp. 616-621
    • Kunin, V.1    Ahren, D.2    Goldovsky, L.3    Janssen, P.4    Ouzounis, C.A.5
  • 85
    • 84885176098 scopus 로고    scopus 로고
    • A genomic update on clostridial phylogeny: Gram-negative spore formers and other misplaced clostridia
    • Yutin N, Galperin MY. 2013. A genomic update on clostridial phylogeny: Gram-negative spore formers and other misplaced clostridia. Environ Microbiol 15:2631–2641. http://dx.doi.org/10.1111/1462-2920.12173.
    • (2013) Environ Microbiol , vol.15 , pp. 2631-2641
    • Yutin, N.1    Galperin, M.Y.2
  • 87
    • 77951246352 scopus 로고    scopus 로고
    • Revised road map to the phylum Firmicutes
    • De Vos P, Garrity GM, Jones D, Krieg NR, Ludwig W, Rainey FA, Schleifer K-H, Whitman WB, 2nd ed, The Firmicutes. Springer, New York, NY
    • Ludwig W, Schleifer KH, Whitman WB. 2009. Revised road map to the phylum Firmicutes, p 1–14. In De Vos P, Garrity GM, Jones D, Krieg NR, Ludwig W, Rainey FA, Schleifer K-H, Whitman WB (ed), Bergey’s manual of systematic bacteriology, 2nd ed, vol 3. The Firmicutes. Springer, New York, NY.
    • (2009) Bergey’s Manual of Systematic Bacteriology , vol.3 , pp. 1-14
    • Ludwig, W.1    Schleifer, K.H.2    Whitman, W.B.3
  • 88
    • 0037249773 scopus 로고    scopus 로고
    • Estimated minimal divergence times of the major bacterial and archaeal phyla
    • Sheridan PP, Freeman KH, Brenchley JE. 2003. Estimated minimal divergence times of the major bacterial and archaeal phyla. Geomicrobiol J 20:1–14. http://dx.doi.org/10.1080/01490450303891.
    • (2003) Geomicrobiol J , vol.20 , pp. 1-14
    • Sheridan, P.P.1    Freeman, K.H.2    Brenchley, J.E.3
  • 90
    • 84928584851 scopus 로고    scopus 로고
    • Genomic diversity of Clostridium difficile strains
    • Janezic S, Rupnik M. 2015. Genomic diversity of Clostridium difficile strains. Res Microbiol 166:353–360. http://dx.doi.org/10.1016/j.resmic.2015.02.002.
    • (2015) Res Microbiol , vol.166 , pp. 353-360
    • Janezic, S.1    Rupnik, M.2
  • 93
    • 84933506535 scopus 로고    scopus 로고
    • Pan-European longitudinal surveillance of antibiotic resistance among prevalent Clostridium difficile ribotypes
    • Freeman J, Vernon J, Morris K, Nicholson S, Todhunter S, Longshaw C, Wilcox MH. 2015. Pan-European longitudinal surveillance of antibiotic resistance among prevalent Clostridium difficile ribotypes. Clin Microbiol Infect 20:248.e9–248.e16. http://dx.doi.org/10.1016/j.cmi.2014.09.017.
    • (2015) Clin Microbiol Infect , vol.20 , pp. 248.e9-248.e16
    • Freeman, J.1    Vernon, J.2    Morris, K.3    Nicholson, S.4    Todhunter, S.5    Longshaw, C.6    Wilcox, M.H.7
  • 96
    • 83755172954 scopus 로고    scopus 로고
    • Emergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage
    • Valiente E, Dawson LF, Cairns MD, Stabler RA, Wren BW. 2012. Emergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage. J Med Microbiol 61:49–56. http://dx.doi.org/10.1099/jmm.0.036194-0.
    • (2012) J Med Microbiol , vol.61 , pp. 49-56
    • Valiente, E.1    Dawson, L.F.2    Cairns, M.D.3    Stabler, R.A.4    Wren, B.W.5
  • 98
    • 34547697437 scopus 로고    scopus 로고
    • Emergence and control of fluoroquinolone-resistant, toxin A-negative, toxin B-positive Clostridium difficile
    • Drudy D, Harnedy N, Fanning S, Hannan M, Kyne L. 2007. Emergence and control of fluoroquinolone-resistant, toxin A-negative, toxin B-positive Clostridium difficile. Infect Control Hosp Epidemiol 28:932–940. http://dx.doi.org/10.1086/519181.
    • (2007) Infect Control Hosp Epidemiol , vol.28 , pp. 932-940
    • Drudy, D.1    Harnedy, N.2    Fanning, S.3    Hannan, M.4    Kyne, L.5
  • 99
    • 0033914385 scopus 로고    scopus 로고
    • Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile responsible for a nosocomial outbreak of Clostridium difficile-associated diarrhea
    • Alfa MJ, Kabani A, Lyerly D, Moncrief S, Neville LM, Al-Barrak A, Harding GK, Dyck B, Olekson K, Embil JM. 2000. Characterization of a toxin A-negative, toxin B-positive strain of Clostridium difficile responsible for a nosocomial outbreak of Clostridium difficile-associated diarrhea. J Clin Microbiol 38:2706–2714.
    • (2000) J Clin Microbiol , vol.38 , pp. 2706-2714
    • Alfa, M.J.1    Kabani, A.2    Lyerly, D.3    Moncrief, S.4    Neville, L.M.5    Al-Barrak, A.6    Harding, G.K.7    Dyck, B.8    Olekson, K.9    Embil, J.M.10
  • 100
    • 70749150720 scopus 로고    scopus 로고
    • Application of multiple-locus variable-number tandem-repeat analysis to determine clonal spread of toxin A-negative Clostridium difficile in a general hospital in Buenos Aires, Argentina
    • Goorhuis A, Legaria MC, van den Berg RJ, Harmanus C, Klaassen CH, Brazier JS, Lumelsky G, Kuijper EJ. 2009. Application of multiple-locus variable-number tandem-repeat analysis to determine clonal spread of toxin A-negative Clostridium difficile in a general hospital in Buenos Aires, Argentina. Clin Microbiol Infect 15:1080–1086. http://dx.doi.org/10.1111/j.1469-0691.2009.02759.x.
    • (2009) Clin Microbiol Infect , vol.15 , pp. 1080-1086
    • Goorhuis, A.1    Legaria, M.C.2    Van Den Berg, R.J.3    Harmanus, C.4    Klaassen, C.H.5    Brazier, J.S.6    Lumelsky, G.7    Kuijper, E.J.8
  • 103
    • 84876189647 scopus 로고    scopus 로고
    • Crosssectional study reveals high prevalence of Clostridium difficile non-PCR ribotype 078 strains in Australian veal calves at slaughter
    • Knight DR, Thean S, Putsathit P, Fenwick S, Riley TV. 2013. Crosssectional study reveals high prevalence of Clostridium difficile non-PCR ribotype 078 strains in Australian veal calves at slaughter. Appl Environ Microbiol 79:2630–2635. http://dx.doi.org/10.1128/AEM.03951-12.
    • (2013) Appl Environ Microbiol , vol.79 , pp. 2630-2635
    • Knight, D.R.1    Thean, S.2    Putsathit, P.3    Fenwick, S.4    Riley, T.V.5
  • 104
    • 70450277819 scopus 로고    scopus 로고
    • Bacteremia with a large clostridial toxin-negative, binary toxin-positive strain of Clostridium difficile
    • Elliott B, Reed R, Chang BJ, Riley TV. 2009. Bacteremia with a large clostridial toxin-negative, binary toxin-positive strain of Clostridium difficile. Anaerobe 15:249–251. http://dx.doi.org/10.1016/j.anaerobe.2009.08.006.
    • (2009) Anaerobe , vol.15 , pp. 249-251
    • Elliott, B.1    Reed, R.2    Chang, B.J.3    Riley, T.V.4
  • 106
    • 84923361060 scopus 로고    scopus 로고
    • Evaluation of the Cepheid Xpert C. Difficile/Epi and Meridian Bioscience illumigene C. Difficile assays for detecting Clostridium difficile ribotype 033 strains
    • Androga G, McGovern A, Elliott B, Chang BJ, Perkins T, Foster N, Riley TV. 2015. Evaluation of the Cepheid Xpert C. difficile/Epi and Meridian Bioscience illumigene C. difficile assays for detecting Clostridium difficile ribotype 033 strains. J Clin Microbiol 53:973–975. http://dx.doi.org/10.1128/JCM.03297-14.
    • (2015) J Clin Microbiol , vol.53 , pp. 973-975
    • Androga, G.1    McGovern, A.2    Elliott, B.3    Chang, B.J.4    Perkins, T.5    Foster, N.6    Riley, T.V.7
  • 108
    • 84896924233 scopus 로고    scopus 로고
    • Sequence similarity of Clostridium difficile strains by analysis of conserved genes and genome content is reflected by their ribotype affiliation
    • Kurka H, Ehrenreich A, Ludwig W, Monot M, Rupnik M, Barbut F, Indra A, Dupuy B, Liebl W. 2014. Sequence similarity of Clostridium difficile strains by analysis of conserved genes and genome content is reflected by their ribotype affiliation. PLoS One 9:e86535. http://dx.doi.org/10.1371/journal.pone.0086535.
    • (2014) Plos One , vol.9
    • Kurka, H.1    Ehrenreich, A.2    Ludwig, W.3    Monot, M.4    Rupnik, M.5    Barbut, F.6    Indra, A.7    Dupuy, B.8    Liebl, W.9
  • 110
    • 58549084151 scopus 로고    scopus 로고
    • A comparison of homologous recombination rates in bacteria and archaea
    • Vos M, Didelot X. 2009. A comparison of homologous recombination rates in bacteria and archaea. ISME J 3:199–208. http://dx.doi.org/10.1038/ismej.2008.93.
    • (2009) ISME J , vol.3 , pp. 199-208
    • Vos, M.1    Didelot, X.2
  • 111
    • 0036969318 scopus 로고    scopus 로고
    • The clostridial mobilisable transposons
    • Adams V, Lyras D, Farrow KA, Rood JI. 2002. The clostridial mobilisable transposons. Cell Mol Life Sci 59:2033–2043. http://dx.doi.org/10.1007/s000180200003.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 2033-2043
    • Adams, V.1    Lyras, D.2    Farrow, K.A.3    Rood, J.I.4
  • 112
    • 80051832374 scopus 로고    scopus 로고
    • Genetic organisation, mobility and predicted functions of genes on integrated, mobile genetic elements in sequenced strains of Clostridium difficile
    • Brouwer MS, Warburton PJ, Roberts AP, Mullany P, Allan E. 2011. Genetic organisation, mobility and predicted functions of genes on integrated, mobile genetic elements in sequenced strains of Clostridium difficile. PLoS One 6:e23014. http://dx.doi.org/10.1371/journal.pone.0023014.
    • (2011) Plos One , vol.6
    • Brouwer, M.S.1    Warburton, P.J.2    Roberts, A.P.3    Mullany, P.4    Allan, E.5
  • 113
    • 84919484042 scopus 로고    scopus 로고
    • The impact of horizontal gene transfer on the biology of Clostridium difficile
    • Roberts AP, Allan E, Mullany P. 2014. The impact of horizontal gene transfer on the biology of Clostridium difficile. Adv Microb Physiol 65: 63–82. http://dx.doi.org/10.1016/bs.ampbs.2014.08.002.
    • (2014) Adv Microb Physiol , vol.65 , pp. 63-82
    • Roberts, A.P.1    Allan, E.2    Mullany, P.3
  • 114
    • 84861220095 scopus 로고    scopus 로고
    • In silico analysis of sequenced strains of Clostridium difficile reveals a related set of conjugative transposons carrying a variety of accessory genes
    • Brouwer MS, Roberts AP, Mullany P, Allan E. 2012. In silico analysis of sequenced strains of Clostridium difficile reveals a related set of conjugative transposons carrying a variety of accessory genes. Mob Genet Elements 2:8–12. http://dx.doi.org/10.4161/mge.19297.
    • (2012) Mob Genet Elements , vol.2 , pp. 8-12
    • Brouwer, M.S.1    Roberts, A.P.2    Mullany, P.3    Allan, E.4
  • 115
    • 84891648569 scopus 로고    scopus 로고
    • Phage C2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains
    • Goh S, Hussain H, Chang BJ, Emmett W, Riley TV, Mullany P. 2013. Phage C2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains. mBio 4(6):e00840-13. http://dx.doi.org/10.1128/mBio.00840-13.
    • (2013) Mbio , vol.4 , Issue.6
    • Goh, S.1    Hussain, H.2    Chang, B.J.3    Emmett, W.4    Riley, T.V.5    Mullany, P.6
  • 116
    • 77957980707 scopus 로고    scopus 로고
    • Origins and evolution of antibiotic resistance
    • Davies J, Davies D. 2010. Origins and evolution of antibiotic resistance. Microbiol Mol Biol Rev 74:417–433. http://dx.doi.org/10.1128/MMBR.00016-10.
    • (2010) Microbiol Mol Biol Rev , vol.74 , pp. 417-433
    • Davies, J.1    Davies, D.2
  • 117
    • 79960946351 scopus 로고    scopus 로고
    • Tn916-like genetic elements: A diverse group of modular mobile elements conferring antibiotic resistance
    • Roberts AP, Mullany P. 2011. Tn916-like genetic elements: a diverse group of modular mobile elements conferring antibiotic resistance. FEMS Microbiol Rev 35:856–871. http://dx.doi.org/10.1111/j.1574-6976.2011.00283.x.
    • (2011) FEMS Microbiol Rev , vol.35 , pp. 856-871
    • Roberts, A.P.1    Mullany, P.2
  • 118
    • 0031808781 scopus 로고    scopus 로고
    • Chloramphenicol resistance in Clostridium difficile is encoded on Tn4453 transposons that are closely related to Tn4451 from Clostridium perfringens
    • Lyras D, Storie C, Huggins AS, Crellin PK, Bannam TL, Rood JI. 1998. Chloramphenicol resistance in Clostridium difficile is encoded on Tn4453 transposons that are closely related to Tn4451 from Clostridium perfringens. Antimicrob Agents Chemother 42:1563–1567.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1563-1567
    • Lyras, D.1    Storie, C.2    Huggins, A.S.3    Crellin, P.K.4    Bannam, T.L.5    Rood, J.I.6
  • 119
    • 0030603250 scopus 로고    scopus 로고
    • A group II intron in a conjugative transposon from the gram-positive bacterium, Clostridium difficile
    • Mullany P, Pallen M, Wilks M, Stephen JR, Tabaqchali S. 1996. A group II intron in a conjugative transposon from the gram-positive bacterium, Clostridium difficile. Gene 174:145–150. http://dx.doi.org/10.1016/0378-1119(96)00511-2.
    • (1996) Gene , vol.174 , pp. 145-150
    • Mullany, P.1    Pallen, M.2    Wilks, M.3    Stephen, J.R.4    Tabaqchali, S.5
  • 120
    • 38649121471 scopus 로고    scopus 로고
    • Tetracycline resistance gene tet(W) in the pathogenic bacterium Clostridium difficile
    • Spigaglia P, Barbanti F, Mastrantonio P. 2008. Tetracycline resistance gene tet(W) in the pathogenic bacterium Clostridium difficile. Antimicrob Agents Chemother 52:770–773. http://dx.doi.org/10.1128/AAC.00957-07.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 770-773
    • Spigaglia, P.1    Barbanti, F.2    Mastrantonio, P.3
  • 121
    • 0028922657 scopus 로고
    • Transfer of macrolidelincosamide- streptogramin-B (MLS) resistance in Clostridium difficile is linked to a gene homologous with toxin A and is mediated by a conjugative transposon, Tn5398
    • Mullany P, Wilks M, Tabaqchali S. 1995. Transfer of macrolidelincosamide- streptogramin-B (MLS) resistance in Clostridium difficile is linked to a gene homologous with toxin A and is mediated by a conjugative transposon, Tn5398. J Antimicrob Chemother 35:305–315. http://dx.doi.org/10.1093/jac/35.2.305.
    • (1995) J Antimicrob Chemother , vol.35 , pp. 305-315
    • Mullany, P.1    Wilks, M.2    Tabaqchali, S.3
  • 122
    • 23744453392 scopus 로고    scopus 로고
    • A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: Methylation of 23S ribosomal RNA at A2503
    • Kehrenberg C, Schwarz S, Jacobsen L, Hansen LH, Vester B. 2005. A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503. Mol Microbiol 57: 1064–1073. http://dx.doi.org/10.1111/j.1365-2958.2005.04754.x.
    • (2005) Mol Microbiol , vol.57 , pp. 1064-1073
    • Kehrenberg, C.1    Schwarz, S.2    Jacobsen, L.3    Hansen, L.H.4    Vester, B.5
  • 123
    • 33645761164 scopus 로고    scopus 로고
    • Distribution of florfenicol resistance genes fexA and cfr among chloramphenicol-resistant Staphylococcus isolates
    • Kehrenberg C, Schwarz S. 2006. Distribution of florfenicol resistance genes fexA and cfr among chloramphenicol-resistant Staphylococcus isolates. Antimicrob Agents Chemother 50:1156–1163. http://dx.doi.org/10.1128/AAC.50.4.1156-1163.2006.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1156-1163
    • Kehrenberg, C.1    Schwarz, S.2
  • 126
    • 80052882560 scopus 로고    scopus 로고
    • Multidrug resistance in European Clostridium difficile clinical isolates
    • Spigaglia P, Barbanti F, Mastrantonio P. 2011. Multidrug resistance in European Clostridium difficile clinical isolates. J Antimicrob Chemother 66:2227–2234. http://dx.doi.org/10.1093/jac/dkr292.
    • (2011) J Antimicrob Chemother , vol.66 , pp. 2227-2234
    • Spigaglia, P.1    Barbanti, F.2    Mastrantonio, P.3
  • 128
    • 84915733904 scopus 로고    scopus 로고
    • Inter- and intraspecies transfer of a Clostridium difficile conjugative transposon conferring resistance to MLSB
    • Wasels F, Monot M, Spigaglia P, Barbanti F, Ma L, Bouchier C, Dupuy B, Mastrantonio P. 2014. Inter- and intraspecies transfer of a Clostridium difficile conjugative transposon conferring resistance to MLSB. Microb Drug Resist 20:555–560. http://dx.doi.org/10.1089/mdr.2014.0015.
    • (2014) Microb Drug Resist , vol.20 , pp. 555-560
    • Wasels, F.1    Monot, M.2    Spigaglia, P.3    Barbanti, F.4    Ma, L.5    Bouchier, C.6    Dupuy, B.7    Mastrantonio, P.8
  • 129
    • 84924339460 scopus 로고    scopus 로고
    • Complete genome sequence of the Clostridium difficile laboratory strain 630 Δerm reveals differences from strain 630, including translocation of the mobile element CTn 5
    • van Eijk E, Anvar S, Browne HP, Leung W, Frank J, Schmitz AM, Roberts AP, Smits W. 2015. Complete genome sequence of the Clostridium difficile laboratory strain 630 Δerm reveals differences from strain 630, including translocation of the mobile element CTn 5. BMCGenomics 16:31. http://dx.doi.org/10.1186/s12864-015-1252-7.
    • (2015) Bmcgenomics , vol.16
    • Van Eijk, E.1    Anvar, S.2    Browne, H.P.3    Leung, W.4    Frank, J.5    Schmitz, A.M.6    Roberts, A.P.7    Smits, W.8
  • 130
    • 65549147639 scopus 로고    scopus 로고
    • Defining the mobilome
    • Siefert JL. 2009. Defining the mobilome. Methods Mol Biol 532:13–27. http://dx.doi.org/10.1007/978-1-60327-853-9_2.
    • (2009) Methods Mol Biol , vol.532 , pp. 13-27
    • Siefert, J.L.1
  • 131
    • 84896992962 scopus 로고    scopus 로고
    • Characterization of temperate phages infecting Clostridium difficile isolates of human and animal origins
    • Sekulovic O, Garneau JR, Neron A, Fortier LC. 2014. Characterization of temperate phages infecting Clostridium difficile isolates of human and animal origins. Appl Environ Microbiol 80:2555–2563. http://dx.doi.org/10.1128/AEM.00237-14.
    • (2014) Appl Environ Microbiol , vol.80 , pp. 2555-2563
    • Sekulovic, O.1    Garneau, J.R.2    Neron, A.3    Fortier, L.C.4
  • 132
    • 84885070363 scopus 로고    scopus 로고
    • Genetically diverse Clostridium difficile strains harboring abundant prophages in an estuarine environment
    • Hargreaves KR, Colvin HV, Patel KV, Clokie JJ, Clokie MR. 2013. Genetically diverse Clostridium difficile strains harboring abundant prophages in an estuarine environment. Appl Environ Microbiol 79:6236–6243. http://dx.doi.org/10.1128/AEM.01849-13.
    • (2013) Appl Environ Microbiol , vol.79 , pp. 6236-6243
    • Hargreaves, K.R.1    Colvin, H.V.2    Patel, K.V.3    Clokie, J.J.4    Clokie, M.R.5
  • 133
    • 36649034890 scopus 로고    scopus 로고
    • Morphological and genetic diversity of temperate phages in Clostridium difficile
    • Fortier LC, Moineau S. 2007. Morphological and genetic diversity of temperate phages in Clostridium difficile. Appl Environ Microbiol 73: 7358–7366. http://dx.doi.org/10.1128/AEM.00582-07.
    • (2007) Appl Environ Microbiol , vol.73 , pp. 7358-7366
    • Fortier, L.C.1    Moineau, S.2
  • 134
    • 84899692742 scopus 로고    scopus 로고
    • What does the talking? Quorum sensing signalling genes discovered in a bacteriophage genome
    • Hargreaves KR, Kropinski AM, Clokie MR. 2014. What does the talking? Quorum sensing signalling genes discovered in a bacteriophage genome. PLoS One 9:e85131. http://dx.doi.org/10.1371/journal.pone.0085131.
    • (2014) Plos One , vol.9
    • Hargreaves, K.R.1    Kropinski, A.M.2    Clokie, M.R.3
  • 135
    • 84908432854 scopus 로고    scopus 로고
    • Abundant and diverse clustered regularly interspaced short palindromic repeat spacers in Clostridium difficile strains and prophages target multiple phage types within this pathogen
    • Hargreaves KR, Flores CO, Lawley TD, Clokie MR. 2014. Abundant and diverse clustered regularly interspaced short palindromic repeat spacers in Clostridium difficile strains and prophages target multiple phage types within this pathogen. mBio 5(5):e01045-13. http://dx.doi.org/10.1128/mBio.01045-13.
    • (2014) Mbio , vol.5 , Issue.5
    • Hargreaves, K.R.1    Flores, C.O.2    Lawley, T.D.3    Clokie, M.R.4
  • 136
    • 0036267740 scopus 로고    scopus 로고
    • Identification of genes that are associated with DNA repeats in prokaryotes
    • Jansen R, Embden JD, Gaastra W, Schouls LM. 2002. Identification of genes that are associated with DNA repeats in prokaryotes. Mol Microbiol 43:1565–1575. http://dx.doi.org/10.1046/j.1365-2958.2002.02839.x.
    • (2002) Mol Microbiol , vol.43 , pp. 1565-1575
    • Jansen, R.1    Embden, J.D.2    Gaastra, W.3    Schouls, L.M.4
  • 137
    • 84886255455 scopus 로고    scopus 로고
    • Horizontal gene transfer converts non-toxigenic Clostridium difficile strains into toxin producers
    • Brouwer MS, Roberts AP, Hussain H, Williams RJ, Allan E, Mullany P. 2013. Horizontal gene transfer converts non-toxigenic Clostridium difficile strains into toxin producers. Nat Commun 4:2601. http://dx.doi.org/10.1038/ncomms3601.
    • (2013) Nat Commun , vol.4
    • Brouwer, M.S.1    Roberts, A.P.2    Hussain, H.3    Williams, R.J.4    Allan, E.5    Mullany, P.6
  • 138
    • 0034022888 scopus 로고    scopus 로고
    • Mobilization of plasmids and chromosomal DNA mediated by the SXT element, a constin found in Vibrio cholerae O139
    • Hochhut B, Marrero J, Waldor MK. 2000. Mobilization of plasmids and chromosomal DNA mediated by the SXT element, a constin found in Vibrio cholerae O139. J Bacteriol 182:2043–2047. http://dx.doi.org/10.1128/JB.182.7.2043-2047.2000.
    • (2000) J Bacteriol , vol.182 , pp. 2043-2047
    • Hochhut, B.1    Marrero, J.2    Waldor, M.K.3
  • 139
    • 31344475729 scopus 로고    scopus 로고
    • A Bacteroides conjugative transposon, CTnERL, can transfer a portion of itself by conjugation without excising from the chromosome
    • Whittle G, Hamburger N, Shoemaker NB, Salyers AA. 2006. A Bacteroides conjugative transposon, CTnERL, can transfer a portion of itself by conjugation without excising from the chromosome. J Bacteriol 188: 1169–1174. http://dx.doi.org/10.1128/JB.188.3.1169-1174.2006.
    • (2006) J Bacteriol , vol.188 , pp. 1169-1174
    • Whittle, G.1    Hamburger, N.2    Shoemaker, N.B.3    Salyers, A.A.4
  • 140
    • 84885302477 scopus 로고    scopus 로고
    • Genetic characteristics of toxigenic Clostridia and toxin gene evolution
    • Popoff MR, Bouvet P. 2013. Genetic characteristics of toxigenic Clostridia and toxin gene evolution. Toxicon 75:63–89. http://dx.doi.org/10.1016/j.toxicon.2013.05.003.
    • (2013) Toxicon , vol.75 , pp. 63-89
    • Popoff, M.R.1    Bouvet, P.2
  • 141
    • 0030220788 scopus 로고    scopus 로고
    • Modification of a PCR ribotyping method for application as a routine typing scheme for Clostridium difficile
    • O’Neill GL, Ogunsola FT, Brazier JS, Duerden BI. 1996. Modification of a PCR ribotyping method for application as a routine typing scheme for Clostridium difficile. Anaerobe 2:205–209. http://dx.doi.org/10.1006/anae.1996.0028.
    • (1996) Anaerobe , vol.2 , pp. 205-209
    • O’Neill, G.L.1    Ogunsola, F.T.2    Brazier, J.S.3    Duerden, B.I.4
  • 142
    • 0037309169 scopus 로고    scopus 로고
    • Rates and consequences of recombination between rRNA operons
    • Hashimoto JG, Stevenson BS, Schmidt TM. 2003. Rates and consequences of recombination between rRNA operons. J Bacteriol 185:966–972. http://dx.doi.org/10.1128/JB.185.3.966-972.2003.
    • (2003) J Bacteriol , vol.185 , pp. 966-972
    • Hashimoto, J.G.1    Stevenson, B.S.2    Schmidt, T.M.3
  • 144
    • 84881580524 scopus 로고    scopus 로고
    • Surface-layer (S-layer) of human and animal Clostridium difficile strains and their behaviour in adherence to epithelial cells and intestinal colonization
    • Spigaglia P, Barketi-Klai A, Collignon A, Mastrantonio P, Barbanti F, Rupnik M, Janezic S, Kansau I. 2013. Surface-layer (S-layer) of human and animal Clostridium difficile strains and their behaviour in adherence to epithelial cells and intestinal colonization. J Med Microbiol 62:1386–1393. http://dx.doi.org/10.1099/jmm.0.056556-0.
    • (2013) J Med Microbiol , vol.62 , pp. 1386-1393
    • Spigaglia, P.1    Barketi-Klai, A.2    Collignon, A.3    Mastrantonio, P.4    Barbanti, F.5    Rupnik, M.6    Janezic, S.7    Kansau, I.8
  • 145
    • 58149168840 scopus 로고    scopus 로고
    • The population genetics of dN/dS
    • Kryazhimskiy S, Plotkin JB. 2008. The population genetics of dN/dS. PLoS Genet 4:e1000304. http://dx.doi.org/10.1371/journal.pgen.1000304.
    • (2008) Plos Genet , vol.4
    • Kryazhimskiy, S.1    Plotkin, J.B.2
  • 146
    • 84928584594 scopus 로고    scopus 로고
    • The complexity and diversity of the pathogenicity locus in Clostridium difficile clade 5
    • Elliott B, Dingle KE, Didelot X, Crook D, Riley TV. 2014. The complexity and diversity of the pathogenicity locus in Clostridium difficile clade 5. Genome Biol Evol 6:3159–3170. http://dx.doi.org/10.1093/gbe/evu248.
    • (2014) Genome Biol Evol , vol.6 , pp. 3159-3170
    • Elliott, B.1    Dingle, K.E.2    Didelot, X.3    Crook, D.4    Riley, T.V.5
  • 150
    • 38449115527 scopus 로고    scopus 로고
    • Annual incidence of MRSA falls in England, but C. Difficile continues to rise
    • Mooney H. 2007. Annual incidence of MRSA falls in England, but C. difficile continues to rise. BMJ 335:958. http://dx.doi.org/10.1136/bmj.39388.597569.DB.
    • (2007) BMJ , vol.335
    • Mooney, H.1
  • 151
    • 84933542220 scopus 로고    scopus 로고
    • Investigation into outbreaks of Clostridium difficile at Stoke Mandeville Hospital, Buckinghamshire Hospitals NHS Trust
    • London, United Kingdom
    • Healthcare Commission. 2006. Investigation into outbreaks of Clostridium difficile at Stoke Mandeville Hospital, Buckinghamshire Hospitals NHS Trust. Commission for Healthcare Audit and Inspection, London, United Kingdom. http://www.buckinghamshirehospitals.nhs.uk/healthcarecommision/HCC-Investigation-into-the-Outbreak-of-Clostridium-difficile.pdf.
    • (2006) Commission for Healthcare Audit and Inspection
  • 153
    • 84881603904 scopus 로고    scopus 로고
    • Germination efficiency of clinical Clostridium difficile spores and correlation with ribotype, disease severity and therapy failure
    • Moore P, Kyne L, Martin A, Solomon K. 2013. Germination efficiency of clinical Clostridium difficile spores and correlation with ribotype, disease severity and therapy failure. J Med Microbiol 62:1405–1413. http://dx.doi.org/10.1099/jmm.0.056614-0.
    • (2013) J Med Microbiol , vol.62 , pp. 1405-1413
    • Moore, P.1    Kyne, L.2    Martin, A.3    Solomon, K.4
  • 154
    • 78650575216 scopus 로고    scopus 로고
    • The diverse sporulation characteristics of Clostridium difficile clinical isolates are not associated with type
    • Burns DA, Heap JT, Minton NP. 2010. The diverse sporulation characteristics of Clostridium difficile clinical isolates are not associated with type. Anaerobe 16:618–622. http://dx.doi.org/10.1016/j.anaerobe.2010.10.001.
    • (2010) Anaerobe , vol.16 , pp. 618-622
    • Burns, D.A.1    Heap, J.T.2    Minton, N.P.3
  • 155
    • 77958132074 scopus 로고    scopus 로고
    • Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile
    • Lanis JM, Barua S, Ballard JD. 2010. Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile. PLoS Pathog 6:e1001061. http://dx.doi.org/10.1371/journal.ppat.1001061.
    • (2010) Plos Pathog , vol.6
    • Lanis, J.M.1    Barua, S.2    Ballard, J.D.3
  • 156
    • 0034924147 scopus 로고    scopus 로고
    • Resistance to moxifloxacin in toxigenic Clostridium difficile isolates is associated with mutations in gyrA
    • Ackermann G, Tang YJ, Kueper R, Heisig P, Rodloff AC, Silva J, Cohen SH. 2001. Resistance to moxifloxacin in toxigenic Clostridium difficile isolates is associated with mutations in gyrA. Antimicrob Agents Chemother 45:2348–2353. http://dx.doi.org/10.1128/AAC.45.8.2348-2353.2001.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 2348-2353
    • Ackermann, G.1    Tang, Y.J.2    Kueper, R.3    Heisig, P.4    Rodloff, A.C.5    Silva, J.6    Cohen, S.H.7
  • 158
    • 27444437759 scopus 로고    scopus 로고
    • Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficileassociated diarrhea: A cohort study during an epidemic in Quebec
    • Pépin J, Saheb N, Coulombe M, Alary M, Corriveau M, Authier S, Leblanc M, Rivard G, Bettez M, Primeau V. 2005. Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficileassociated diarrhea: a cohort study during an epidemic in Quebec. Clin Infect Dis 41:1254–1260. http://dx.doi.org/10.1086/496986.
    • (2005) Clin Infect Dis , vol.41 , pp. 1254-1260
    • Pépin, J.1    Saheb, N.2    Coulombe, M.3    Alary, M.4    Corriveau, M.5    Authier, S.6    Leblanc, M.7    Rivard, G.8    Bettez, M.9    Primeau, V.10
  • 161
    • 3843093832 scopus 로고    scopus 로고
    • Nosocomial diarrhoea due to Clostridium difficile
    • Riley TV. 2004. Nosocomial diarrhoea due to Clostridium difficile. Curr Opin Infect Dis 17:323–327. http://dx.doi.org/10.1097/01.qco.0000136930.83167.9b.
    • (2004) Curr Opin Infect Dis , vol.17 , pp. 323-327
    • Riley, T.V.1
  • 162
    • 0024545882 scopus 로고
    • Nosocomial acquisition of Clostridium difficile infection
    • McFarland LV, Mulligan ME, Kwok RY, Stamm WE. 1989. Nosocomial acquisition of Clostridium difficile infection. NEngl J Med 320:204–210. http://dx.doi.org/10.1056/NEJM198901263200402.
    • (1989) Nengl J Med , vol.320 , pp. 204-210
    • McFarland, L.V.1    Mulligan, M.E.2    Kwok, R.Y.3    Stamm, W.E.4
  • 164
    • 3843137350 scopus 로고    scopus 로고
    • Molecular epidemiology of hospital-associated and community-acquired Clostridium difficile infection in a Swedish county
    • Noren T, Akerlund T, Back E, Sjoberg L, Persson I, Alriksson I, Burman LG. 2004. Molecular epidemiology of hospital-associated and community-acquired Clostridium difficile infection in a Swedish county. J Clin Microbiol 42:3635–3643. http://dx.doi.org/10.1128/JCM.42.8.3635-3643.2004.
    • (2004) J Clin Microbiol , vol.42 , pp. 3635-3643
    • Noren, T.1    Akerlund, T.2    Back, E.3    Sjoberg, L.4    Persson, I.5    Alriksson, I.6    Burman, L.G.7
  • 169
    • 19344363493 scopus 로고    scopus 로고
    • Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada
    • Pepin J, Alary ME, Valiquette L, Raiche E, Ruel J, Fulop K, Godin D, Bourassa C. 2005. Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada. Clin Infect Dis 40:1591–1597. http://dx.doi.org/10.1086/430315.
    • (2005) Clin Infect Dis , vol.40 , pp. 1591-1597
    • Pepin, J.1    Alary, M.E.2    Valiquette, L.3    Raiche, E.4    Ruel, J.5    Fulop, K.6    Godin, D.7    Bourassa, C.8
  • 170
    • 84863661973 scopus 로고    scopus 로고
    • Relapse versus reinfection: Recurrent Clostridium difficile infection following treatment with fidaxomicin or vancomycin
    • Figueroa I, Johnson S, Sambol SP, Goldstein EJ, Citron DM, Gerding DN. 2012. Relapse versus reinfection: recurrent Clostridium difficile infection following treatment with fidaxomicin or vancomycin. Clin Infect Dis 55:S104–S109. http://dx.doi.org/10.1093/cid/cis357.
    • (2012) Clin Infect Dis , vol.55 , pp. S104-S109
    • Figueroa, I.1    Johnson, S.2    Sambol, S.P.3    Goldstein, E.J.4    Citron, D.M.5    Gerding, D.N.6
  • 171
    • 84898883105 scopus 로고    scopus 로고
    • Whole-genome sequencing demonstrates that fidaxomicin is superior to vancomycin for preventing reinfection and relapse of infection with Clostridium difficile
    • Eyre DW, Babakhani F, Griffiths D, Seddon J, Del Ojo Elias C, Gorbach SL, Peto TE, Crook DW, Walker AS. 2014. Whole-genome sequencing demonstrates that fidaxomicin is superior to vancomycin for preventing reinfection and relapse of infection with Clostridium difficile. J Infect Dis 209:1446–1451. http://dx.doi.org/10.1093/infdis/jit598.
    • (2014) J Infect Dis , vol.209 , pp. 1446-1451
    • Eyre, D.W.1    Babakhani, F.2    Griffiths, D.3    Seddon, J.4    Del Ojo Elias, C.5    Gorbach, S.L.6    Peto, T.E.7    Crook, D.W.8    Walker, A.S.9
  • 172
    • 84870167616 scopus 로고    scopus 로고
    • Community-acquired Clostridium difficile infection: An emerging entity
    • Khanna S, Pardi DS. 2012. Community-acquired Clostridium difficile infection: an emerging entity. Clin Infect Dis 55:1741–1742. http://dx.doi.org/10.1093/cid/cis722.
    • (2012) Clin Infect Dis , vol.55 , pp. 1741-1742
    • Khanna, S.1    Pardi, D.S.2
  • 174
    • 79960555026 scopus 로고    scopus 로고
    • Incidence of and risk factors for community-associated Clostridium difficile infection: A nested case-control study
    • Kuntz JL, Chrischilles EA, Pendergast JF, Herwaldt LA, Polgreen PM. 2011. Incidence of and risk factors for community-associated Clostridium difficile infection: a nested case-control study. BMC Infect Dis 11: 194. http://dx.doi.org/10.1186/1471-2334-11-194.
    • (2011) BMC Infect Dis , vol.11
    • Kuntz, J.L.1    Chrischilles, E.A.2    Pendergast, J.F.3    Herwaldt, L.A.4    Polgreen, P.M.5
  • 175
    • 84875308051 scopus 로고    scopus 로고
    • Clostridium difficile
    • Squire MM, Riley TV. 2012. Clostridium difficile infection: the next big thing! Microbiol Aus 33:163–164.
    • (2012) Microbiol Aus , vol.33 , pp. 163-164
    • Squire, M.M.1    Riley, T.V.2
  • 177
    • 84905584223 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms of the tcdC gene and presence of the binary toxin gene predict recurrent episodes of Clostridium difficile infection
    • Stewart DB, Berg AS, Hegarty JP. 2014. Single nucleotide polymorphisms of the tcdC gene and presence of the binary toxin gene predict recurrent episodes of Clostridium difficile infection. Ann Surg 260:299–304. http://dx.doi.org/10.1097/SLA.0000000000000469.
    • (2014) Ann Surg , vol.260 , pp. 299-304
    • Stewart, D.B.1    Berg, A.S.2    Hegarty, J.P.3
  • 179
    • 28844494379 scopus 로고    scopus 로고
    • Clostridium difficile
    • Songer JG, Anderson MA. 2006. Clostridium difficile: an important pathogen of food animals. Anaerobe 12:1–4. http://dx.doi.org/10.1016/j.anaerobe.2005.09.001.
    • (2006) Anaerobe , vol.12 , pp. 1-4
    • Songer, J.G.1    Anderson, M.A.2
  • 180
    • 80053132801 scopus 로고    scopus 로고
    • Clostridium difficile
    • Keessen EC, Gaastra W, Lipman LJ. 2011. Clostridium difficile infection in humans and animals, differences and similarities. Vet Microbiol 153: 205–217. http://dx.doi.org/10.1016/j.vetmic.2011.03.020.
    • (2011) Vet Microbiol , vol.153 , pp. 205-217
    • Keessen, E.C.1    Gaastra, W.2    Lipman, L.J.3
  • 182
    • 60149085427 scopus 로고    scopus 로고
    • High diversity of Clostridium difficile genotypes isolated from a single poultry farm producing replacement laying hens
    • Zidaric V, Zemljic M, Janezic S, Kocuvan A, Rupnik M. 2008. High diversity of Clostridium difficile genotypes isolated from a single poultry farm producing replacement laying hens. Anaerobe 14:325–327. http://dx.doi.org/10.1016/j.anaerobe.2008.10.001.
    • (2008) Anaerobe , vol.14 , pp. 325-327
    • Zidaric, V.1    Zemljic, M.2    Janezic, S.3    Kocuvan, A.4    Rupnik, M.5
  • 183
    • 77957019873 scopus 로고    scopus 로고
    • Longitudinal investigation of Clostridium difficile shedding in piglets
    • Weese JS, Wakeford T, Reid-Smith R, Rousseau J, Friendship R. 2010. Longitudinal investigation of Clostridium difficile shedding in piglets. Anaerobe 16:501–504. http://dx.doi.org/10.1016/j.anaerobe.2010.08.001.
    • (2010) Anaerobe , vol.16 , pp. 501-504
    • Weese, J.S.1    Wakeford, T.2    Reid-Smith, R.3    Rousseau, J.4    Friendship, R.5
  • 184
    • 77954942781 scopus 로고    scopus 로고
    • Evaluation of Clostridium difficile in dogs and the household environment
    • Weese JS, Finley R, Reid-Smith RR, Janecko N, Rousseau J. 2010. Evaluation of Clostridium difficile in dogs and the household environment. Epidemiol Infect 138:1100–1104. http://dx.doi.org/10.1017/S0950268809991312.
    • (2010) Epidemiol Infect , vol.138 , pp. 1100-1104
    • Weese, J.S.1    Finley, R.2    Reid-Smith, R.R.3    Janecko, N.4    Rousseau, J.5
  • 185
    • 0347625736 scopus 로고    scopus 로고
    • Outbreak of Clostridium difficileassociated disease in a small animal veterinary teaching hospital
    • Weese JS, Armstrong J. 2003. Outbreak of Clostridium difficileassociated disease in a small animal veterinary teaching hospital. J Vet Intern Med 17:813–816. http://dx.doi.org/10.1111/j.1939-1676.2003.tb02519.x.
    • (2003) J Vet Intern Med , vol.17 , pp. 813-816
    • Weese, J.S.1    Armstrong, J.2
  • 186
    • 79960419351 scopus 로고    scopus 로고
    • Clostridium difficile
    • Thean S, Elliott B, Riley TV. 2011. Clostridium difficile in horses in Australia—a preliminary study. J Med Microbiol 60:1188–1192. http://dx.doi.org/10.1099/jmm.0.030908-0.
    • (2011) J Med Microbiol , vol.60 , pp. 1188-1192
    • Thean, S.1    Elliott, B.2    Riley, T.V.3
  • 187
    • 84880290882 scopus 로고    scopus 로고
    • Presence of Clostridium difficile PCR ribotype clusters related to 033, 078 and 045 in diarrhoeic calves in Germany
    • Schneeberg A, Neubauer H, Schmoock G, Grossmann E, Seyboldt C. 2013. Presence of Clostridium difficile PCR ribotype clusters related to 033, 078 and 045 in diarrhoeic calves in Germany. J Med Microbiol 62:1190–1198. http://dx.doi.org/10.1099/jmm.0.056473-0.
    • (2013) J Med Microbiol , vol.62 , pp. 1190-1198
    • Schneeberg, A.1    Neubauer, H.2    Schmoock, G.3    Grossmann, E.4    Seyboldt, C.5
  • 189
    • 0026347074 scopus 로고
    • Gastrointestinal carriage of Clostridium difficile in cats and dogs attending veterinary clinics
    • Riley TV, Adams JE, O’Neill GL, Bowman RA. 1991. Gastrointestinal carriage of Clostridium difficile in cats and dogs attending veterinary clinics. Epidemiol Infect 107:659–665. http://dx.doi.org/10.1017/S0950268800049359.
    • (1991) Epidemiol Infect , vol.107 , pp. 659-665
    • Riley, T.V.1    Adams, J.E.2    O’Neill, G.L.3    Bowman, R.A.4
  • 190
    • 79960415770 scopus 로고    scopus 로고
    • Prevalence of Clostridium difficile in horses
    • Medina-Torres CE, Weese JS, Staempfli HR. 2011. Prevalence of Clostridium difficile in horses. Vet Microbiol 152:212–215. http://dx.doi.org/10.1016/j.vetmic.2011.04.012.
    • (2011) Vet Microbiol , vol.152 , pp. 212-215
    • Medina-Torres, C.E.1    Weese, J.S.2    Staempfli, H.R.3
  • 191
    • 84884266022 scopus 로고    scopus 로고
    • Prevalence of gastrointestinal Clostridium difficile carriage in Australian sheep and lambs
    • Knight DR, Riley TV. 2013. Prevalence of gastrointestinal Clostridium difficile carriage in Australian sheep and lambs. Appl Environ Microbiol 79:5689–5692. http://dx.doi.org/10.1128/AEM.01888-13.
    • (2013) Appl Environ Microbiol , vol.79 , pp. 5689-5692
    • Knight, D.R.1    Riley, T.V.2
  • 194
    • 80051815521 scopus 로고    scopus 로고
    • Epidemiology of Clostridium difficile on a veal farm: Prevalence, molecular characterization and tetracycline resistance
    • Costa MC, Stampfli HR, Arroyo LG, Pearl DL, Weese JS. 2011. Epidemiology of Clostridium difficile on a veal farm: prevalence, molecular characterization and tetracycline resistance. Vet Microbiol 152:379–384. http://dx.doi.org/10.1016/j.vetmic.2011.05.014.
    • (2011) Vet Microbiol , vol.152 , pp. 379-384
    • Costa, M.C.1    Stampfli, H.R.2    Arroyo, L.G.3    Pearl, D.L.4    Weese, J.S.5
  • 196
    • 84894245665 scopus 로고    scopus 로고
    • Shedding of Clostridium difficile PCR ribotype 078 by zoo animals, and report of an unstable metronidazoleresistant isolate from a zebra foal (Equus quagga burchellii)
    • Alvarez-Perez S, Blanco JL, Martinez-Nevado E, Pelaez T, Harmanus C, Kuijper E, Garcia ME. 2014. Shedding of Clostridium difficile PCR ribotype 078 by zoo animals, and report of an unstable metronidazoleresistant isolate from a zebra foal (Equus quagga burchellii). Vet Microbiol 169:218–222. http://dx.doi.org/10.1016/j.vetmic.2013.12.018.
    • (2014) Vet Microbiol , vol.169 , pp. 218-222
    • Alvarez-Perez, S.1    Blanco, J.L.2    Martinez-Nevado, E.3    Pelaez, T.4    Harmanus, C.5    Kuijper, E.6    Garcia, M.E.7
  • 199
    • 34250660545 scopus 로고    scopus 로고
    • Prevalence of PCR ribotypes among Clostridium difficile isolates from pigs, calves, and other species
    • Keel K, Brazier JS, Post KW, Weese S, Songer JG. 2007. Prevalence of PCR ribotypes among Clostridium difficile isolates from pigs, calves, and other species. J Clin Microbiol 45:1963–1964. http://dx.doi.org/10.1128/JCM.00224-07.
    • (2007) J Clin Microbiol , vol.45 , pp. 1963-1964
    • Keel, K.1    Brazier, J.S.2    Post, K.W.3    Weese, S.4    Songer, J.G.5
  • 200
    • 79960251969 scopus 로고    scopus 로고
    • Clostridium difficile
    • Rupnik M, Songer JG. 2010. Clostridium difficile: its potential as a source of foodborne disease. Adv Food Nutr Res 60:53–66. http://dx.doi.org/10.1016/S1043-4526(10)60003-4.
    • (2010) Adv Food Nutr Res , vol.60 , pp. 53-66
    • Rupnik, M.1    Songer, J.G.2
  • 201
    • 71849085180 scopus 로고    scopus 로고
    • Clostridium difficile
    • Weese JS. 2010. Clostridium difficile in food—innocent bystander or serious threat? Clin Microbiol Infect 16:3–10. http://dx.doi.org/10.1111/j.1469-0691.2009.03108.x.
    • (2010) Clin Microbiol Infect , vol.16 , pp. 3-10
    • Weese, J.S.1
  • 203
    • 77955820324 scopus 로고    scopus 로고
    • Clostridium difficile
    • Rupnik M. 2010. Clostridium difficile: (re)emergence of zoonotic potential. Clin Infect Dis 51:583–584. http://dx.doi.org/10.1086/655693.
    • (2010) Clin Infect Dis , vol.51 , pp. 583-584
    • Rupnik, M.1
  • 204
    • 84917694526 scopus 로고    scopus 로고
    • Nationwide surveillance study of Clostridium difficile in Australian neonatal pigs shows high prevalence and heterogeneity of PCR ribotypes
    • Knight DR, Squire MM, Riley TV. 2015. Nationwide surveillance study of Clostridium difficile in Australian neonatal pigs shows high prevalence and heterogeneity of PCR ribotypes. Appl Environ Microbiol 81:119–123. http://dx.doi.org/10.1128/AEM.03032-14.
    • (2015) Appl Environ Microbiol , vol.81 , pp. 119-123
    • Knight, D.R.1    Squire, M.M.2    Riley, T.V.3
  • 205
    • 84892709254 scopus 로고    scopus 로고
    • Clostridium difficile
    • Squire MM, Riley TV. 2013. Clostridium difficile infection in humans and piglets: a ‘One Health’ opportunity. Curr Top Microbiol Immunol 365:299–314. http://dx.doi.org/10.1007/82_2012_237.
    • (2013) Curr Top Microbiol Immunol , vol.365 , pp. 299-314
    • Squire, M.M.1    Riley, T.V.2
  • 206
    • 68349097517 scopus 로고    scopus 로고
    • Is Clostridium difficile a threat to Australia’s biosecurity?
    • Riley TV. 2009. Is Clostridium difficile a threat to Australia’s biosecurity? Med J Aust 190:661–662.
    • (2009) Med J Aust , vol.190 , pp. 661-662
    • Riley, T.V.1
  • 207
    • 77957823336 scopus 로고    scopus 로고
    • Relatedness of human and animal Clostridium difficile PCR ribotype 078 isolates determined on the basis of multilocus variable-number tandem-repeat analysis and tetracycline resistance
    • Bakker D, Corver J, Harmanus C, Goorhuis A, Keessen EC, Fawley WN, Wilcox MH, Kuijper EJ. 2010. Relatedness of human and animal Clostridium difficile PCR ribotype 078 isolates determined on the basis of multilocus variable-number tandem-repeat analysis and tetracycline resistance. J Clin Microbiol 48:3744–3749. http://dx.doi.org/10.1128/JCM.01171-10.
    • (2010) J Clin Microbiol , vol.48 , pp. 3744-3749
    • Bakker, D.1    Corver, J.2    Harmanus, C.3    Goorhuis, A.4    Keessen, E.C.5    Fawley, W.N.6    Wilcox, M.H.7    Kuijper, E.J.8


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