Epidemiology of Clostridium difficile on a veal farm: Prevalence, molecular characterization and tetracycline resistance

Veterinary Microbiology

Volumn 152, Issue 3-4, 2011, Pages 379-384

  Costa, M C ^a   Stampfli H R ^a   Arroyo, L G ^a   Pearl, D L ^a   Weese, J S ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

Oxytetracycline; Public health; Ribotype 078; Tet(O)

Indexed keywords

BACTERIAL DNA; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; OXYTETRACYCLINE; TETRACYCLINE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL SHEDDING; BACTERIUM CULTURE; BACTERIUM ISOLATION; CALF (BOVINE); CDTA GENE; CLOSTRIDIUM DIFFICILE; CONTROLLED STUDY; FECES ANALYSIS; MALE; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR EPIDEMIOLOGY; MULTIPLEX POLYMERASE CHAIN REACTION; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; NONHUMAN; PREVALENCE; RIBOTYPING; TCDA GENE; TCDB GENE;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL TOXINS; CATTLE; CATTLE DISEASES; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; ENTEROTOXINS; MALE; POLYMERASE CHAIN REACTION; PREVALENCE; RECTUM; RIBOTYPING; TETRACYCLINE RESISTANCE;

BACTERIA (MICROORGANISMS); BOS; BOVINAE; CLOSTRIDIUM DIFFICILE;

EID: 80051815521     PISSN: 03781135     EISSN: 18732542     Source Type: Journal    
DOI: 10.1016/j.vetmic.2011.05.014     Document Type: Article

References (28)

1. Arroyo L.G., Kruth S.A., Willey B.M., Staempfli H.R., Low D.E., Weese J.S. PCR ribotyping of Clostridium difficile isolates originating from human and animal sources. J. Med. Microbiol. 2005, 54:163-166.
2. Bauer M.P., Notermans D.W., van Benthem B.H., Brazier J.S., Wilcox M.H., Rupnik M., Monnet D.L., van Dissel J.T., Kuijper E.J. Clostridium difficile infection in Europe: a hospital-based survey. Lancet 2011, 377:63-73. ECDIS Study Group.
3. Bidet P., Barbut F., Lalande V., Burghoffer B., Petit J. Development of a new PCR ribotyping method for Clostridium difficile based on ribosomal RNA gene sequencing. FEMS Microbiol. Lett. 1999, 175:261-266.
4. Curry S.R., Marsh J.W., Muto C.A., O'Leary M.M., Pasculle A.W., Harrison L.H. tcdC genotypes associated with severe TcdC truncation in an epidemic clone and other strains of Clostridium difficile. J. Clin. Microbiol. 2007, 45:215-221.
5. Goorhuis A., Bakker D., Corver J., Debast S.B., Harmanus C., Notermans D.W., Bergwerff A.A., Dekker F.W., Kuijper E.J. Emergence of Clostridium difficile infection due to a new hypervirulent strain, polymerase chain reaction ribotype 078. Clin. Infect. Dis. 2008, 47:1162-1170.
6. Hammitt M.C., Bueschel D.M., Keel M.K., Glock R.D., Cuneo P., Deyoung D.W., Reggiardo C., Trinh H.T., Songer J.G. A possible role for Clostridium difficile in the etiology of calf enteritis. Vet. Microbiol. 2008, 27:343-352.
7. Hoffer E., Haechler H., Frei R., Stephan R. Low occurrence of Clostridium difficile in fecal samples of healthy calves and pigs at slaughter and in minced meat in Switzerland. J. Food Prot. 2010, 73:973-975.
8. Jhung M.A., Thompson A.D., Killgore G.E., Zukowski W.E., Songer G., Warny M., Johnson S., Gerding D.N., McDonald L.C., Limbago B.M. Toxinotype V Clostridium difficile in humans and food animals. Emerg. Infect. Dis. 2008, 14:1039-1045.
9. Kato H., Kato N., Watanabe K., Iwai N., Nakamura H., Yamamoto T., Suzuki K., Kim S.M., Chong Y., Wasito E.B. Identification of toxin A-negative, toxin B-positive Clostridium difficile by PCR. J. Clin. Microbiol. 1998, 36:2178-2182.
10. Keel M.K., Songer J.G. The comparative pathology of Clostridium difficile-associated disease. Vet. Pathol. 2006, 43:225-240.
11. Keel K., Brazier J.S., Post K.W., Weese S., Songer J.G. Prevalence of PCR ribotypes among Clostridium difficile isolates from pigs, calves, and other species. J. Clin. Microbiol. 2007, 45:1963-1964.
12. Lemee L., Dhalliun A., Testelin S., Mattrat M., Maillard K., Lemeland J., Pons J. Multiplex PCR targeting tpi (triose phosphate isomerase), tcdA (Toxin A), and tcdB (Toxin B) genes for toxigenic culture of Clostridium difficile. J. Clin. Microbiol. 2004, 42:5710-5714.
13. Mulvey M.R., Boyd D.A., Gravel D., Hutchinson J., Kelly S., McGeer A., Moore D., Simor A., Suh K.N., Taylor G., Weese J.S., Miller M. Hypervirulent Clostridium difficile strains in hospitalized patients, Canada. Emerg. Infect. Dis. 2010, 16:678-681. Canadian Nosocomial Infection Surveillance Program.
14. Ng L.K., Martin I., Alfa M., Mulvey M. Multiplex PCR for the detection of tetracycline resistant genes. Mol Cell Probes 2001, 15:209-215.
15. Porter, M.C., Reggiardo, C., Bueschel, D.M., Keel, M.K., Songer, J.G., 2002. Association of Clostridium difficile with bovine neonatal diarrhea. In: Proc. 45th Ann. Mtg. Amer. Assoc. Vet. Lab. Diagn., St. Louis, MO, U.S.A.
16. Post K.W., Songer J.G. Antimicrobial susceptibility of Clostridium difficile isolated from neonatal pigs with enteritis. Anaerobe 2004, 10:47-50.
17. Rodriguez-Palacios A., Staempfli H.R., Duffield T., Peregrine A.S., Trotz-Williams L., Arroyo L., Brazier J.S., Weese J.S. Clostridium difficile PCR ribotypes in calves, Canada. Emerg. Infect. Dis. 2006, 12:1730-1736.
18. Rodriguez-Palacios A., Staempfli H.R., Duffield T., Weese J.S. Clostridium difficile in retail ground meat, Canada. Emerg. Infect. Dis. 2007, 13:485-487.
19. Rupnik M., Widmer A., Zimmermann O., Eckert C. Clostridium difficile Toxinotype V Ribotype 078, in animals and humans. J. Clin. Microbiol. 2008, 46:2146.
20. Schmidt C., Löffler B., Ackermann G. Antimicrobial phenotypes and molecular basis in clinical strains of Clostridium difficile. Diagn. Microbiol. Infect. Dis. 2007, 59:1-5.
21. Songer J.G., Trinh H.T., Killgore G.E., Thompson A.D., McDonald L.C., Limbago B.M. Clostridium difficile in retail meat products, USA, 2007. Emerg. Infect. Dis. 2009, 15:819-821.
22. Spigaglia P., Mastrantonio P. Molecular analysis of the pathogenicity locus and polymorphism in the putative negative regulator of toxin production (TcdC) among Clostridium difficile clinical isolates. J. Clin. Microbiol. 2002, 40:3470-3475.
23. Spigaglia P., Mastrantonio P. Comparative analysis of Clostridium difficile clinical isolates belonging to different genetic lineages and time periods. J. Med. Microbiol. 2004, 53:1129-1136.
24. Spigaglia P., Barbanti F., Mastrantonio P. Tetracycline resistance gene tet(W) in the pathogenic bacterium Clostridium difficile. Antimicrob. Agents Chemother. 2008, 52:770-773.
25. Stubbs S., Rupnik M., Gibert M., Brazier J., Duerden B., Popoff M. Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficile. FEMS Microbiol. Lett. 2000, 186:307-312.
26. Warny M., Pepin J., Fang A., Killgore G., Thompson A., Brazier J., Frost E., McDonald L.C. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet 2005, 366:1079-1084.
27. Weese J.S., Avery B.P., Rousseau J., Reid-Smith R.J. Detection and enumeration of Clostridium difficile spores in retail beef and pork. Appl. Environ. Microbiol. 2009, 75:5009-5011.
28. Zilberberg M.D., Shorr A.F., Kollef M.H. Increase in adult Clostridium difficile-related hospitalizations and case-fatality rate United States, 2000-2005. Emerg. Infect. Dis. 2008, 14:829-831.