Efficacy of different cleaning and disinfection methods against clostridium difficile spores: Importance of physical removal versus sporicidal inactivation

Infection Control and Hospital Epidemiology

Volumn 33, Issue 12, 2012, Pages 1255-1258

  Rutala, William A ^a,b   Gergen, Maria F ^b   Weber, David J ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA HOSPITALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISINFECTANT AGENT;

ARTICLE; BACTERIAL SPORE; BACTERIAL VIABILITY; CLEANING; CLINICAL EFFECTIVENESS; CLOSTRIDIUM DIFFICILE; DISINFECTION; HEAT TREATMENT; INTERMETHOD COMPARISON; NONHUMAN; SUSPENSION;

CLOSTRIDIUM DIFFICILE; CROSS INFECTION; DISINFECTANTS; ENTEROCOLITIS, PSEUDOMEMBRANOUS; EQUIPMENT CONTAMINATION; HOUSEKEEPING, HOSPITAL; HUMANS; INFECTION CONTROL; MECHANICAL PROCESSES; SPORES, BACTERIAL;

EID: 84869169946     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/668434     Document Type: Article

References (11)

1. Centers for Disease Control and Prevention. Vital signs: preventing Clostridium difficile infections. MMWR Morb Mortal Wkly Rep 2011;61:1-6.
2. Miller BA, Chen LF, Sexton DJ, Anderson DJ. Comparison of the burdens of hospital-onset, healthcare facility-associated Clostridium difficile infection and of healthcare-associated infection due to methicillin-resistant Staphylococcus aureus in community hospitals. Infect Control Hosp Epidemiol 2011;32: 387-390.
3. Weber DJ, Rutala WA, Miller MB, Huslage K, Sickbert-Bennett E. Role of hospital surfaces in the transmission of emerging health care-associated pathogens: norovirus, Clostridium difficile, and Acinetobacter species. Am J Infect Control 2010;38:S25-S33.
4. Weber DJ, Rutala WA. The role of the environment in trans- mission of Clostridium difficile infection in healthcare facilities. Infect Control Hosp Epidemiol 2011;32:207-209.
5. Shaughnessy MK, Micielli RL, DePestel DD, et al. Evaluation of hospital room assignment and acquisition of Clostridium difficile infection. Infect Control Hosp Epidemiol 2011;32:201-206.
6. Orenstein R, Aronhalt KC, McManus JE, Fedraw LA. A targeted strategy to wipe out Clostridium difficile. Infect Control Hosp Epidemiol 2011:32:1137-1139.
7. Boyce JM, Havill NL, Otter JA, et al. Impact of hydrogen peroxide vapor room decontamination on Clostridium difficile environmental contamination and transmission in a healthcare setting. Infect Control Hosp Epidemiol 2008;29:723-729.
8. Association of Official Analytical Chemists (AOAC). AOAC official method 966.04: sporicidal activity of disinfectants. In: Official methods of analysis of AOAC International. Vol 1. 16th ed. 5th revision. Gaithersburg, MD: AOAC, 1999.
9. Cohen SH, Gerding DN, Johnson S, et al. Clinical practice guide- lines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Disease Society of America (IDSA). Infect Control Hosp Epidemiol 2010;31:431-455.
10. Rutala WA, Weber DJ. Are room decontamination units needed to prevent transmission of environmental pathogens? Infect Control Hosp Epidemiol 2011;32:743-747.
11. Sinai H, Copper C, Maillard J-M. Efficacy of "sporicidal" wipes against Clostridium difficile. Am J Infect Control 2011;39:212-218.