Toxinotype V Clostridium difficile in humans and food animals

Emerging Infectious Diseases

Volumn 14, Issue 7, 2008, Pages 1039-1045

  Jhung, Michael A ^a,f   Thompson, Angela D ^a   Killgore, George E ^a   Zukowski, Walter E ^b   Songer, Glenn ^c   Warny, Michael ^d   Johnson, Stuart ^b,e   Gerding, Dale N ^b,e   McDonald, L Clifford ^a   Limbago, Brandi M ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b HINES VA HOSPITAL   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d Acambis   (United States)

^e LOYOLA UNIVERSITY CHICAGO   (United States)

^f NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINDAMYCIN; CLOSTRIDIUM TOXIN; GATIFLOXACIN; LEVOFLOXACIN; MOXIFLOXACIN;

ADULT; AGED; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL INFECTION; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BACTERIUM ISOLATE; CLINICAL ARTICLE; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE TOXINOTYPE V; FEMALE; GENE DELETION; HUMAN; MALE; MOLECULAR GENETICS; NONHUMAN; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

AGED; AGED, 80 AND OVER; ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CATTLE; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; COMMUNITY-ACQUIRED INFECTIONS; DISEASE RESERVOIRS; ENTEROTOXINS; FEMALE; GASTROINTESTINAL DISEASES; HUMANS; MALE; MIDDLE AGED; REPRESSOR PROTEINS; RIBOTYPING; SUS SCROFA;

EID: 46349103285     PISSN: 10806040     EISSN: 10806059     Source Type: Journal    
DOI: 10.3201/eid1407.071641     Document Type: Article

References (38)

1. Warny M, Pepin J, Fang A, Killgore G, Thompson A, Brazier J, et al. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet. 2005;366:1079-84. DOI: 10.1016/S0140-6736(05)67420-X
2. Kuijper EJ, Coignard B, Tull P. Emergence of Clostridium difficile-associated disease in North America and Europe. Clin Microbiol Infect. 2006;12(Suppl 6):2-18. DOI: 10.1111/j.1469-0691.2006.01580.x
3. Sunenshine RH, McDonald LC. Clostridium difficile-associated disease: new challenges from an established pathogen. Cleve Clin J Med. 2006;73:187-97.
4. McDonald LC, Killgore GE, Thompson A, Owens RC Jr, Kazakova SV, Sambol SP, et al. An epidemic, toxin gene-variant strain of Clostridium difficile. N Engl J Med. 2005;353:2433-41. DOI: 10.1056/NEJMoa051590
5. Songer JG, Post KW, Larson DJ, Jost BH, Glock RD. Enteric infection of neonatal swine with Clostridium difficile. Journal of Swine Health and Production. 2000;8:185-9.
6. Songer JG, Post KW, Larson DJ, Jost BH, Glock RD. Clostridium difficile as a cause of porcine neonatal enteritis. Birmingham (AL): American Association of Veterinary Laboratory Diagnosticians; 2000.
7. Post KW, Songer JG, Jost BH, Glock RD, Holtcamp A. The emergence of Clostridium difficile as a cause of porcine neonatal enteritis. Nashville (TN): American Association of Swine Veterinarians; 2001.
8. Keel K, Brazier JS, Post KW, Weese S, Songer JG. Prevalence of PCR ribotypes among Clostridium difficile isolates from pigs, calves, and other species. J Clin Microbiol. 2007;45:1963-4. DOI: 10.1128/JCM.00224-07
9. Rodriguez-Palacios A, Staempfli HR, Duffield T, Weese JS. Clostridium difficile in retail ground meat, Canada. Emerg Infect Dis. 2007;13:485-7.
10. Rodriguez-Palacios A, Staempfli HR, Duffield T, Peregrine AS, Trotz-Williams LA, Arroyo LG, et al. Clostridium difficile PCR ribotypes in calves, Canada. Emerg Infect Dis. 2006;12:1730-6.
11. McDonald LC, Coignard B, Dubberke E, Song X, Horan T, Kutty PK. Recommendations for surveillance of Clostridium difficile-associated disease. Infect Control Hosp Epidemiol. 2007;28:140-5. DOI: 10.1086/511798
12. Clabots CR, Johnson S, Bettin KM, Mathie PA, Mulligan ME, Schaberg DR, et al. Development of a rapid and efficient restriction endonuclease analysis typing system for Clostridium difficile and correlation with other typing systems. J Clin Microbiol. 1993;31:1870-5.
13. Klaassen CH, van Haren HA, Horrevorts AM. Molecular fingerprinting of Clostridium difficile isolates: pulsed-field gel electrophoresis versus amplified fragment length polymorphism. J Clin Microbiol. 2002;40:101-4. DOI: 10.1128/JCM.40.1.101-104.2002
14. Rupnik M, Avesani V, Janc M, von Eichel-Streiber C, Delmee M. A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates. J Clin Microbiol. 1998;36:2240-7.
15. Spigaglia P, Mastrantonio P. Molecular analysis of the pathogenicity locus and polymorphism in the putative negative regulator of toxin production (TcdC) among Clostridium difficile clinical isolates. J Clin Microbiol. 2002;40:3470-5. DOI: 10.1128/JCM.40.9.3470-3475.2002
16. National Committee for Clinical Laboratory Standards. Methods of antimicrobial susceptibility testing of anaerobic bacteria. 6th ed. Approved standard M11-A6. Villanova (PA): The Committee; 2004.
17. Songer JG, Anderson MA. Clostridium difficile: an important pathogen of food animals. Anaerobe. 2006;12:1-4. DOI: 10.1016/j.anaerobe.2005. 09.001
18. Songer JG. The emergence of Clostridium difficile as a pathogen of food animals. Anim Health Res Rev. 2004;5:321-6. DOI: 10.1079/AHR200492
19. Frazier KS, Herron AJ, Hines ME II, Gaskin JM, Altman NH. Diagnosis of enteritis and enterotoxemia due to Clostridium difficile in captive ostriches (Struthio camelus). J Vet Diagn Invest. 1993;5:623-5.
20. Marks SL, Kather EJ, Kass PH, Melli AC. Genotypic and phenotypic characterization of Clostridium perfringens and Clostridium difficile in diarrheic and healthy dogs. J Vet Intern Med. 2002;16:533-40. DOI: 10.1892/0891-6640(2002)016〈0533:GAPCOP〉2.3.CO;2
21. Weese JS, Weese HE, Bourdeau TL, Staempfli HR. Suspected Clostridium difficile-associated diarrhea in two cats. J Am Vet Med Assoc. 2001;218:1436-9, 1421.
22. Weese JS, Staempfli HR, Prescott JF. A prospective study of the roles of Clostridium difficile and enterotoxigenic Clostridium perfringens in equine diarrhoea. Equine Vet J. 2001;33:403-9. DOI: 10.2746/ 042516401776249534
23. O'Neill G, Adams JE, Bowman RA, Riley TV. A molecular characterization of Clostridium difficile isolates from humans, animals and their environments. Epidemiol Infect. 1993;111:257-64.
24. Lefebvre SL, Arroyo LG, Weese JS. Epidemic Clostridium difficile strain in hospital visitation dog. Emerg Infect Dis. 2006;12:1036-7.
25. Kutty PK, Benoit SR, Woods CW, Sena AC, Naggie S, Frederick J, et al. Assessment of Clostridium difficile-associated disease surveillance definitions, North Carolina, 2005. Infect Control Hosp Epidemiol. 2008;29:197-202. DOI: 10.1086/528813
26. Noren T, Akerlund T, Back E, Sjoberg L, Persson I, Alriksson I, et al. Molecular epidemiology of hospital-associated and community-acquired Clostridium difficile infection in a Swedish county. J Clin Microbiol. 2004;42:3635-43. DOI: 10.1128/JCM.42.8.3635-3643.2004
27. MacCannell DR, Louie TJ, Gregson DB, Laverdiere M, Labbe AC, Laing F, et al. Molecular analysis of Clostridium difficile PCR ribotype 027 isolates from Eastern and Western Canada. J Clin Microbiol. 2006;44:2147-52. DOI: 10.1128/JCM.02563-05
28. Limbago B, Long CM, Thompson AD, Killgore GE, Hannett G, Havill N, et al. Isolation and characterization of Clostridium difficile responsible for community-associated disease. International Meeting of the American Society for Microbiology; 2007 May 21-25; Toronto, Ontario, Canada.
29. Barbut F, Gariazzo B, Bonne L, Lalande V, Burghoffer B, Luiuz R, et al. Clinical features of Clostridium difficile-associated infections and molecular characterization of strains: results of a retrospective study, 2000-2004. Infect Control Hosp Epidemiol. 2007;28:131-9. DOI: 10.1086/511794
30. Geric B, Rupnik M, Gerding DN, Grabnar M, Johnson S. Distribution of Clostridium difficile variant toxinotypes and strains with binary toxin genes among clinical isolates in an American hospital. J Med Microbiol. 2004;53:887-94. DOI: 10.1099/jmm.0.45610-0
31. Rupnik M, Kato N, Grabnar M, Kato H. New types of toxin A-negative, toxin B-positive strains among Clostridium difficile isolates from Asia. J Clin Microbiol. 2003;41:1118-25. DOI: 10.1128/JCM.41.3.1118-1125.2003
32. Stubbs S, Rupnik M, Gibert M, Brazier J, Duerden B, Popoff M. Production of actin-specific ADP-ribosyltransferase (binary toxin) by strains of Clostridium difficile. FEMS Microbiol Lett. 2000;186:307-12. DOI: 10.1111/j.1574-6968.2000.tb09122.x
33. Pituch H, Kreft D, Obuch-Woszczatynski P, Wultanska D, Meisel-Mikolajczyk F, Luczak M, et al. Clonal spread of a Clostridium difficile strain with a complete set of toxin A, toxin B, and binary toxin genes among Polish patients with Clostridium difficile-associated diarrhea. J Clin Microbiol. 2005;43:472-5. DOI: 10.1128/JCM.43.1.472-475.2005
34. Buttrini M, Spigaglia P, Somenzi P, Zerbini L, Dettori G, Chezzi C, et al. Epidemiology of Clostridium difficile strains with binary-toxin genes among clinical isolates in an Italian hospital. 2nd International Clostridium difficile Symposium; 2007 June 6-9; Maribor, Slovenia.
35. Pirs T, Avbersek J, Ocepek M, Rupnik M. Isolation of Clostridium difficile from food animals in Slovenia. 2nd International Clostridium difficile Symposium; 2007 June 6-9; Maribor, Slovenia.
36. Curry SR, Marsh JW, Muto CA, O'Leary MM, Pasculle AW, Harrison LH. tcdC genotypes associated with severe TcdC truncation in an epidemic clone and other strains of Clostridium difficile. J Clin Microbiol. 2007;45:215-21. DOI: 10.1128/JCM.01599-06
37. McFarland LV, Beneda HW, Clarridge JE, Raugi GJ. Implications of the changing face of Clostridium difficile disease for health care practitioners. Am J Infect Control. 2007;35:237-53. DOI: 10.1016/j.ajic.2006.06. 004
38. Arroyo LG, Kruth SA, Willey BM, Staempfli HR, Low DE, Weese JS. PCR ribotyping of Clostridium difficile isolates originating from human and animal sources. J Med Microbiol. 2005;54:163-6. DOI: 10.1099/jmm.0.45805-0