Reference assays for Clostridium difficile infection: One or two gold standards?

Journal of Clinical Pathology

Volumn 64, Issue 1, 2011, Pages 1-5

  Planche, Timothy ^a,b   Wilcox, Mark ^a,b  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN;

ACCURACY; BACTERIUM ISOLATION; BIOASSAY; CELL CYTOTOXICITY ASSAY; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; DIAGNOSTIC TEST; DIARRHEA; FECES ANALYSIS; HUMAN; INFECTION SENSITIVITY; INTERMETHOD COMPARISON; NONHUMAN; PRIORITY JOURNAL; REVIEW; SENSITIVITY AND SPECIFICITY; STANDARDIZATION; TOXIGENIC CULTURE;

BACTERIOLOGICAL TECHNIQUES; CLOSTRIDIUM DIFFICILE; ENTEROCOLITIS, PSEUDOMEMBRANOUS; FECES; HUMANS;

EID: 78650828068     PISSN: 00219746     EISSN: 14724146     Source Type: Journal    
DOI: 10.1136/jcp.2010.080135     Document Type: Review

References (30)

1. HPA and DH. Clostridium difficile Infection: How to Deal with the Problem. DH publications, 2008.
2. Settle CD, Wilcox MH. Comparison of the oxoid Clostridium difficile toxin a detection kit with cytotoxin detection by a cytopathic effect method examined at 4, 6, 24 and 48 h. Clin Microbiol Infect 1999;5:698-701.
3. Delmee M, Van Broeck J, Simon A, et al. Laboratory diagnosis of Clostridium difficile-associated diarrhoea: a plea for culture. J Med Microbiol 2005;54:187-91. (Pubitemid 40868006)
4. Sloan LM, Duresko BJ, Gustafson DR, et al. Comparison of real-time PCR for detection of the tcdC gene with four toxin immunoassays and culture in diagnosis of Clostridium difficile infection. J Clin Microbiol 2008;46:1996-2001.
5. Thonnard J, Carreer F, Avesani V, et al. Toxin a detection on Clostridium difficile colonies from 24-h cultures. Clin Microbiol Infect 1996;2:50-4. (Pubitemid 126682078)
6. Schue V, Green GA, Monteil H. Comparison of the ToxA test with cytotoxicity assay and culture for the detection of Clostridium difficile-associated diarrhoea disease. J Med Microbiol 1994;41:316-18.
7. DiPersio JR, Varga FJ, Conwell DL, et al. Development of a rapid enzyme immunoassay for Clostridium difficile toxin a and its use in the diagnosis of C. difficile-associated disease. J Clin Microbiol 1991;29:2724-30.
8. Merz CS, Kramer C, Forman M, et al. Comparison of four commercially available rapid enzyme immunoassays with cytotoxin assay for detection of Clostridium difficile toxin(s) from stool specimens. J Clin Microbiol 1994;32:1142-7.
9. Fedorko DP, Engler HD, O'Shaughnessy EM, et al. Evaluation of two rapid assays for detection of Clostridium difficile toxin a in stool specimens. J Clin Microbiol 1999;37:3044-7.
10. Kelly MT, Champagne SG, Sherlock CH, et al. Commercial latex agglutination test for detection of Clostridium difficile-associated diarrhea. J Clin Microbiol 1987;25:1244-7.
11. Vanpoucke H, De Baere T, Claeys G, et al. Evaluation of six commercial assays for the rapid detection of Clostridium difficile toxin and/or antigen in stool specimens. Clin Microbiol Infect 2001;7:55-64. (Pubitemid 34960272)
12. Barbut F, Braun M, Burghoffer B, et al. Rapid detection of toxigenic strains of Clostridium difficile in diarrheal stools by real-time PCR. J Clin Microbiol 2009;47:1276-7.
13. Eastwood K, Else P, Charlett A, et al. Comparison of nine commercially available Clostridium difficile toxin detection assays, a real-time PCR assay for C. difficile tcdB, and a glutamate dehydrogenase detection assay to cytotoxin testing and cytotoxigenic culture methods. J Clin Microbiol 2009;47:3211-17.
14. Brazier JS. The diagnosis of Clostridium difficile-associated disease. J Antimicrob Chemother 1998;41(Suppl C):29-40.
15. Samore MH, DeGirolami PC, Tlucko A, et al. Clostridium difficile colonization and diarrhea at a tertiary care hospital. Clin Infect Dis 1994;18:181-7.
16. Clabots CR, Johnson S, Olson MM, et al. Acquisition of Clostridium difficile by hospitalized patients: evidence for colonized new admissions as a source of infection. J Infect Dis 1992;166:561-7.
17. Phillips KD, Rogers PA. Rapid detection and presumptive identification of Clostridium difficile by p-cresol production on a selective medium. J Clin Pathol 1981;34:642-4.
18. Aronsson B, Mollby R, Nord CE. Antimicrobial agents and Clostridium difficile in acute enteric disease: epidemiological data from Sweden, 1980-1982. J Infect Dis 1985;151:476-81.
19. Shim JK, Johnson S, Samore MH, et al. Primary symptomless colonisation by Clostridium difficile and decreased risk of subsequent diarrhoea. Lancet 1998;351:633-6. (Pubitemid 28098446)
20. McFarland LV, Mulligan ME, Kwok RY, et al. Nosocomial acquisition of Clostridium difficile infection. N Engl J Med 1989;320:204-10.
21. Gerding DN, Olson MM, Peterson LR, et al. Clostridium difficile-associated diarrhea and colitis in adults. A prospective case-controlled epidemiologic study. Arch Intern Med 1986;146:95-100.
22. Johal SS, Hammond J, Solomon K, et al. Clostridium difficile associated diarrhoea in hospitalised patients: onset in the community and hospital and role of flexible sigmoidoscopy. Gut 2004;53:673-7.
23. George WL, Rolfe RD, Harding GK, et al. Clostridium difficile and cytotoxin in feces of patients with antimicrobial agent-associated pseudomembranous colitis. Infection 1982;10:205-8.
24. George WL, Rolfe RD, Finegold SM. Clostridium difficile and its cytotoxin in feces of patients with antimicrobial agent-associated diarrhea and miscellaneous conditions. J Clin Microbiol 1982;15:1049-53.
25. Lashner BA, Todorczuk J, Sahm DF, et al. Clostridium difficile culture-positive toxin-negative diarrhea. Am J Gastroenterol 1986;81:940-3.
26. Bond F, Payne G, Borriello SP, et al. Usefulness of culture in the diagnosis of Clostridium difficile infection. Eur J Clin Microbiol Infect Dis 1995;14:223-6.
27. Riley TV, O'Neill GL, Bowman RA, et al. Clostridium difficile-associated diarrhoea: epidemiological data from Western Australia. Epidemiol Infect 1994;113:13-20.
28. Peterson LR, Olson MM, Shanholtzer CJ, et al. Results of a prospective, 18-month clinical evaluation of culture, cytotoxin testing, and culturette brand (CDT) latex testing in the diagnosis of Clostridium difficile-associated diarrhea. Diagn Microbiol Infect Dis 1988;10:85-91.
29. Planche T, Aghaizu A, Holliman R, et al. Diagnosis of Clostridium difficile infection by toxin detection kits: a systematic review. Lancet Infect Dis 2008;8:777-84.
30. Crobach MJ, Dekkers OM, Wilcox MH, et al. European society of clinical microbiology and infectious diseases (ESCMID): data review and recommendations for diagnosing Clostridium difficile-infection (CDI). Clin Microbiol Infect 2009;15:1053-66.