Hydrolysis enhances bioavailability of proanthocyanidin-derived metabolites and improves β-cell function in glucose intolerant rats

Journal of Nutritional Biochemistry

Volumn 26, Issue 8, 2015, Pages 850-859

  Yang, Kaiyuan ^a   Hashemi, Zohre ^a   Han, Wei ^a   Jin, Alena ^a   Yang, Han ^a   Ozga, Jocelyn ^a   Li, Liang ^a   Chan, Catherine B ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Bioavailability; Flavonoids; Glucose homeostasis; Insulin secretion; Pancreatic islet; Proanthocyanidins

Indexed keywords

DELPHINIDIN; EPICATECHIN; GALLOCATECHIN; GLUCURONIDE 4' O METHYL EPIGALLOCATECHIN; PROANTHOCYANIDIN; PRODELPHINIDIN A1; PRODELPHINIDIN B; UNCLASSIFIED DRUG; GLUCAGON; GLUCOSE BLOOD LEVEL; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG HYDROLYSIS; FOOD INTAKE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLYCEMIC CONTROL; HYDROPHILIC INTERACTION CHROMATOGRAPHY; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIPID DIET; LOW FAT DIET; MALE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PEA; RAT; SEED HUSK; ANIMAL; BIOAVAILABILITY; BLOOD; COMPARATIVE STUDY; DIETARY SUPPLEMENT; DRUG EFFECTS; GLUCOSE TOLERANCE TEST; HYDROLYSIS; METABOLISM; SECRETION (PROCESS); SPRAGUE DAWLEY RAT;

PISUM SATIVUM; RATTUS;

ANIMALS; BIOLOGICAL AVAILABILITY; BLOOD GLUCOSE; BODY COMPOSITION; DIET, FAT-RESTRICTED; DIET, HIGH-FAT; DIETARY SUPPLEMENTS; GLUCAGON; GLUCOSE TOLERANCE TEST; HYDROLYSIS; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MALE; PROANTHOCYANIDINS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84931570277     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2015.03.002     Document Type: Article

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