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Volumn 94, Issue 2, 2005, Pages 170-181

The absorption, metabolism and excretion of flavan-3-ols and procyanidins following the ingestion of a grape seed extract by rats

Author keywords

Absorption; Excretion; Flavan 3 ols; HPLC MS MS; Metabolism; Procyanidins; Rats

Indexed keywords

CATECHIN; DIMER; DRUG METABOLITE; EPICATECHIN; EPICATECHIN GALLATE; FLAVAN 3 OL; FLAVANOL DERIVATIVE; GLUCURONIDE; GRAPE SEED EXTRACT; OLIGOMER; PLANT EXTRACT; POLYMER; PROANTHOCYANIDIN; PROCYANIDIN; PROCYANIDIN DERIVATIVE; TETRAMER; TRIMER; UNCLASSIFIED DRUG;

EID: 25444482129     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1079/BJN20051480     Document Type: Article
Times cited : (277)

References (49)
  • 1
    • 0034969156 scopus 로고    scopus 로고
    • Masking of antioxidant capacity by the interaction of flavonoids with protein
    • Arts MJ, Haenen GR, Voss HP & Bast A (2001) Masking of antioxidant capacity by the interaction of flavonoids with protein. Food Chem Toxicol 39, 787-791.
    • (2001) Food Chem. Toxicol. , vol.39 , pp. 787-791
    • Arts, M.J.1    Haenen, G.R.2    Voss, H.P.3    Bast, A.4
  • 3
    • 0035543069 scopus 로고    scopus 로고
    • Absorption and urinary excretion of (-)-epicatechin after administration of different levels of cocoa powder or (-)-epicatechin in rats
    • Baba S, Osakabe N, Natsume M, Muto Y, Takizawa T & Terao J (2001) Absorption and urinary excretion of (-)-epicatechin after administration of different levels of cocoa powder or (-)-epicatechin in rats. J Agric Food Chem 49, 6050-6056.
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 6050-6056
    • Baba, S.1    Osakabe, N.2    Natsume, M.3    Muto, Y.4    Takizawa, T.5    Terao, J.6
  • 6
    • 3042613032 scopus 로고    scopus 로고
    • Classification and biosynthesis of secondary plant products: An overview
    • [G Goldberg, editor]. British Nutrition Foundation. London: Chapman & Hall
    • Crozier A (2003) Classification and biosynthesis of secondary plant products: an overview. In Plants: Diet and Health, pp. 27-48 [G Goldberg, editor]. British Nutrition Foundation. London: Chapman & Hall.
    • (2003) Plants: Diet and Health , pp. 27-48
    • Crozier, A.1
  • 8
    • 0037427824 scopus 로고    scopus 로고
    • Liquid chromatography with atmospheric pressure chemical ionisation and electrospray ionisation mass spectrometry of flavonoids with triple-quadrupole and ion trap instruments
    • de Rijke E, Zappey H, Ariese F, Gooijer C & Brinkman UATh (2003) Liquid chromatography with atmospheric pressure chemical ionisation and electrospray ionisation mass spectrometry of flavonoids with triple-quadrupole and ion trap instruments. J Chromatogr A 984, 45-58.
    • (2003) J. Chromatogr. A , vol.984 , pp. 45-58
    • de Rijke, E.1    Zappey, H.2    Ariese, F.3    Gooijer, C.4    Brinkman, U.A.Th.5
  • 10
    • 0033745131 scopus 로고    scopus 로고
    • Polymeric proanthocyanidins are catabolized by human colonic microflora into low-molecular-weight phenolic acids
    • Déprez S, Brezillon C, Rabot S, Philippe C, Mila I, Lapierre C & Scalbert A (2000) Polymeric proanthocyanidins are catabolized by human colonic microflora into low-molecular-weight phenolic acids. J Nutr 130, 2733-2738.
    • (2000) J. Nutr. , vol.130 , pp. 2733-2738
    • Déprez, S.1    Brezillon, C.2    Rabot, S.3    Philippe, C.4    Mila, I.5    Lapierre, C.6    Scalbert, A.7
  • 16
    • 0001585772 scopus 로고    scopus 로고
    • The structure of cranberry proanthocyanidins which inhibit adherence of uropathogenic P-fimbriated Escherichia coli in vitro
    • Foo LY, Lu Y, Howell AB & Vorsa N (2000) The structure of cranberry proanthocyanidins which inhibit adherence of uropathogenic P-fimbriated Escherichia coli in vitro. Phytochemistry 54, 173-181.
    • (2000) Phytochemistry , vol.54 , pp. 173-181
    • Foo, L.Y.1    Lu, Y.2    Howell, A.B.3    Vorsa, N.4
  • 17
    • 0001805268 scopus 로고    scopus 로고
    • Investigation of proanthocyanidins by HPLC with electrospray ionisation mass spectrometry
    • Friedrich W, Ebenhardt A & Galensa R (2000) Investigation of proanthocyanidins by HPLC with electrospray ionisation mass spectrometry. Eur Food Res Technol 211, 56-64.
    • (2000) Eur. Food Res. Technol. , vol.211 , pp. 56-64
    • Friedrich, W.1    Ebenhardt, A.2    Galensa, R.3
  • 20
    • 0037260750 scopus 로고    scopus 로고
    • Study of the collision-induced radical cleavage of flavonoid glycosides using negative electrospray ionisation tandem quadrupole mass spectrometry
    • Hvattum E & Ekeberg D (2002) Study of the collision-induced radical cleavage of flavonoid glycosides using negative electrospray ionisation tandem quadrupole mass spectrometry. J Mass Spectrom 38, 43-49.
    • (2002) J. Mass Spectrom , vol.38 , pp. 43-49
    • Hvattum, E.1    Ekeberg, D.2
  • 21
    • 0032819143 scopus 로고    scopus 로고
    • Increase in oxidative potential of rat plasma by oral administration of proanthocyanidin-rich extract from grape seeds
    • Koga T, Moro K, Nakamori K, Yamakoshi J, Hosoyama H, Kataoka S & Ariga T (1999) Increase in oxidative potential of rat plasma by oral administration of proanthocyanidin-rich extract from grape seeds. J Agric Food Chem 47, 1892-1897.
    • (1999) J. Agric. Food Chem. , vol.47 , pp. 1892-1897
    • Koga, T.1    Moro, K.2    Nakamori, K.3    Yamakoshi, J.4    Hosoyama, H.5    Kataoka, S.6    Ariga, T.7
  • 24
    • 8444233189 scopus 로고    scopus 로고
    • Flavonoid metabolites in human plasma and urine after the consumption of red onions: Analysis by liquid chromatography with photodiode array and full scan tandem mass spectrometric detection
    • Mullen W, Boitier A, Stewart AJ & Crozier A (2004) Flavonoid metabolites in human plasma and urine after the consumption of red onions: analysis by liquid chromatography with photodiode array and full scan tandem mass spectrometric detection. J Chromatogr A 1058, 163-168.
    • (2004) J. Chromatogr. A , vol.1058 , pp. 163-168
    • Mullen, W.1    Boitier, A.2    Stewart, A.J.3    Crozier, A.4
  • 26
    • 0242691717 scopus 로고    scopus 로고
    • Metabolism of grape seed polyphenols in the rat
    • Nakamura Y & Tonogai Y (2003) Metabolism of grape seed polyphenols in the rat. J Agric Food Chem 51, 7215-7225.
    • (2003) J. Agric. Food Chem. , vol.51 , pp. 7215-7225
    • Nakamura, Y.1    Tonogai, Y.2
  • 27
    • 0037376885 scopus 로고    scopus 로고
    • Structures of (-)-epicatechin glucuronide identified from plasma and urine after oral ingestion of (-)-epicatechin: Differences between human and rat
    • Natsume M, Osakabe N, Oyama M, Sasaki M, Baba S, Nakamura Y, Osawa T & Terao J (2003) Structures of (-)-epicatechin glucuronide identified from plasma and urine after oral ingestion of (-)-epicatechin: differences between human and rat. Free Rad Biol Med 34, 840-849.
    • (2003) Free Rad. Biol. Med. , vol.34 , pp. 840-849
    • Natsume, M.1    Osakabe, N.2    Oyama, M.3    Sasaki, M.4    Baba, S.5    Nakamura, Y.6    Osawa, T.7    Terao, J.8
  • 28
    • 0031820964 scopus 로고    scopus 로고
    • Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues
    • Piskula MK & Terao J (1998) Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues. J Nutr 128, 1172-1178.
    • (1998) J. Nutr. , vol.128 , pp. 1172-1178
    • Piskula, M.K.1    Terao, J.2
  • 29
    • 0043286281 scopus 로고    scopus 로고
    • Fruits and vegetables in the prevention of cellular oxidative damage
    • Prior R (2003) Fruits and vegetables in the prevention of cellular oxidative damage. Am J Clin Nutr 78, 5705-5785.
    • (2003) Am. J. Clin. Nutr. , vol.78 , pp. 5705-5785
    • Prior, R.1
  • 30
    • 0033867415 scopus 로고    scopus 로고
    • Epicatechin in human plasma: In vivo determination and effect of chocolate consumption on plasma oxidation status
    • Rein D, Lotito S, Holt RR, Keen CL, Schmitz HH & Fraga CG (2000) Epicatechin in human plasma: in vivo determination and effect of chocolate consumption on plasma oxidation status. J Nutr 130, 2109S-2114S.
    • (2000) J. Nutr. , vol.130
    • Rein, D.1    Lotito, S.2    Holt, R.R.3    Keen, C.L.4    Schmitz, H.H.5    Fraga, C.G.6
  • 33
    • 46549093879 scopus 로고
    • Changes and importance of oligomeric procyanidins during maturation of grape seeds
    • Romeyer FM, Macheix J-J & Sapis J-C (1986) Changes and importance of oligomeric procyanidins during maturation of grape seeds. Phytochemistry 25, 219-221.
    • (1986) Phytochemistry , vol.25 , pp. 219-221
    • Romeyer, F.M.1    Macheix, J.-J.2    Sapis, J.-C.3
  • 34
    • 0028945097 scopus 로고
    • Platelet rebound effect of alcohol withdrawal and wine drinking in rats
    • Ruf JC, Berger JL & Renaud S (1995) Platelet rebound effect of alcohol withdrawal and wine drinking in rats. Arterioscler Thromb Vasc Biol 15, 140-144.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 140-144
    • Ruf, J.C.1    Berger, J.L.2    Renaud, S.3
  • 35
    • 0032830879 scopus 로고    scopus 로고
    • Liquid chromatography with electrospray ionisation mass spectrometric detection of phenolic compounds from Olea europaea
    • Ryan D, Robards K, Prenzler P, Jardine D, Herlt T & Antolovich M (1999) Liquid chromatography with electrospray ionisation mass spectrometric detection of phenolic compounds from Olea europaea. J Chromatogr A 855, 529-537.
    • (1999) J. Chromatogr. A , vol.855 , pp. 529-537
    • Ryan, D.1    Robards, K.2    Prenzler, P.3    Jardine, D.4    Herlt, T.5    Antolovich, M.6
  • 37
    • 0028903522 scopus 로고
    • Comparative flava-3-ol composition of seeds from different grape varieties
    • Santos-Buelga C, Francia-Aricha EM & Escibano-Bailón MT (1995) Comparative flava-3-ol composition of seeds from different grape varieties. Food Chem 53, 197-201.
    • (1995) Food Chem. , vol.53 , pp. 197-201
    • Santos-Buelga, C.1    Francia-Aricha, E.M.2    Escibano-Bailón, M.T.3
  • 38
    • 0033863355 scopus 로고    scopus 로고
    • Dietary intake and bioavailability of polyphenols
    • Scalbert A & Williamson G (2000) Dietary intake and bioavailability of polyphenols. J Nutr 130, 2073S-2085S.
    • (2000) J Nutr. , vol.130
    • Scalbert, A.1    Williamson, G.2
  • 39
    • 0242405601 scopus 로고    scopus 로고
    • Analysis of polyphenolic antioxidants in star fruit using liquid chromatography and mass spectrometry
    • Shui G & Leong LP (2004) Analysis of polyphenolic antioxidants in star fruit using liquid chromatography and mass spectrometry. J Chromatogr A 1022, 67-75.
    • (2004) J. Chromatogr. A , vol.1022 , pp. 67-75
    • Shui, G.1    Leong, L.P.2
  • 41
    • 0037316092 scopus 로고    scopus 로고
    • Cocoa and chocolate flavonoids: Implications for cardiovascular health
    • Steinberg FM, Bearden MM & Keen CL (2003) Cocoa and chocolate flavonoids: implications for cardiovascular health. J Am Diet Assoc 103, 215-223.
    • (2003) J. Am. Diet. Assoc. , vol.103 , pp. 215-223
    • Steinberg, F.M.1    Bearden, M.M.2    Keen, C.L.3
  • 42
    • 0032892216 scopus 로고    scopus 로고
    • Isolation and purification of dimeric and trimeric procyanidins from grape seeds
    • Sun B, Belchior GP, Ricardo da Silva JM & Spranger MI (1999) Isolation and purification of dimeric and trimeric procyanidins from grape seeds. J Chromatogr A 841, 115-121.
    • (1999) J. Chromatogr. A , vol.841 , pp. 115-121
    • Sun, B.1    Belchior, G.P.2    Ricardo da Silva, J.M.3    Spranger, M.I.4
  • 45
    • 4143081627 scopus 로고    scopus 로고
    • Supplementation with grape seed polyphenols results in increased urinary excretion of 3-hydroxyphenylpropionic acid, an important metabolite of proanthocyanidins in humans
    • Ward NC, Croft KD, Puddey IB & Hodgson JM (2004) Supplementation with grape seed polyphenols results in increased urinary excretion of 3-hydroxyphenylpropionic acid, an important metabolite of proanthocyanidins in humans. J Agric Food Chem 52, 5545-5549.
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 5545-5549
    • Ward, N.C.1    Croft, K.D.2    Puddey, I.B.3    Hodgson, J.M.4
  • 46
    • 0034982460 scopus 로고    scopus 로고
    • Catechins are bioavailable in men and women drinking black tea throughout the day
    • Warden BA, Smith LS, Beecher GR, Balentine DA & Clevidence BA (2001) Catechins are bioavailable in men and women drinking black tea throughout the day. J Nutr 131, 1731-1737.
    • (2001) J. Nutr. , vol.131 , pp. 1731-1737
    • Warden, B.A.1    Smith, L.S.2    Beecher, G.R.3    Balentine, D.A.4    Clevidence, B.A.5
  • 47
    • 0035839159 scopus 로고    scopus 로고
    • Evaluation of quadrupole time-of-flight tandem mass spectrometry and ion-trap multiple-stage mass spectrometry for differentiation of C-glycosidic flavonoid isomers
    • Waridel P, Wolfender J-L, Ndjoko K, Hobby KR, Major HJ & Hostettmann K (2001) Evaluation of quadrupole time-of-flight tandem mass spectrometry and ion-trap multiple-stage mass spectrometry for differentiation of C-glycosidic flavonoid isomers. J Chromatogr A 926, 29-41.
    • (2001) J. Chromatogr. A , vol.926 , pp. 29-41
    • Waridel, P.1    Wolfender, J.-L.2    Ndjoko, K.3    Hobby, K.R.4    Major, H.J.5    Hostettmann, K.6
  • 48
    • 0037077393 scopus 로고    scopus 로고
    • Procyanidin-rich extract from grape seeds prevents cataract formation in hereditary cataractous (ICR/f) rats
    • Yamakoshi J, Saito M, Kataoka S & Tokutake S (2002) Procyanidin-rich extract from grape seeds prevents cataract formation in hereditary cataractous (ICR/f) rats. J Agric Food Chem 50, 4983-4988.
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 4983-4988
    • Yamakoshi, J.1    Saito, M.2    Kataoka, S.3    Tokutake, S.4


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