메뉴 건너뛰기




Volumn 75, Issue , 2015, Pages 10-24

In vitro skin models as a tool in optimization of drug formulation

Author keywords

Animal skin; Human skin; In vitro permeation models; Skin therapy; Topical formulations

Indexed keywords

DRUG CARRIER; DRUG VEHICLE; LIPID; SILICONE; ARTIFICIAL MEMBRANE;

EID: 84929709743     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2015.02.018     Document Type: Review
Times cited : (168)

References (169)
  • 1
    • 84873133587 scopus 로고    scopus 로고
    • Formulation, characterization and evaluation of an optimized microemulsion formulation of griseofulvin for topical application
    • N. Aggarwal, S. Goindi, and R. Khurana Formulation, characterization and evaluation of an optimized microemulsion formulation of griseofulvin for topical application Colloids Surf. B Biointerf. 105 2013 158 166
    • (2013) Colloids Surf. B Biointerf. , vol.105 , pp. 158-166
    • Aggarwal, N.1    Goindi, S.2    Khurana, R.3
  • 2
    • 84907029228 scopus 로고    scopus 로고
    • Development of alginate-reinforced chitosan nanoparticles utilizing W/O nanoemulsification/internal crosslinking technique for transdermal delivery of rabeprazole
    • T.A. Ahmed, and K.M. El-Say Development of alginate-reinforced chitosan nanoparticles utilizing W/O nanoemulsification/internal crosslinking technique for transdermal delivery of rabeprazole Life Sci. 110 2014 35 43
    • (2014) Life Sci. , vol.110 , pp. 35-43
    • Ahmed, T.A.1    El-Say, K.M.2
  • 3
    • 84902324688 scopus 로고    scopus 로고
    • Itraconazole-ghydroxypropyl-β-cyclodextrin loaded deformable liposomes: In vitro skin penetration studies and antifunhal efficacy using Candida albicans as model
    • A.H. Alomrani, G.A. Shazly, A.A. Amara, and M.M. Badran Itraconazole-ghydroxypropyl-β-cyclodextrin loaded deformable liposomes: in vitro skin penetration studies and antifunhal efficacy using Candida albicans as model Colloids Surf. B: Biointerf. 121 2014 74 81
    • (2014) Colloids Surf. B: Biointerf. , vol.121 , pp. 74-81
    • Alomrani, A.H.1    Shazly, G.A.2    Amara, A.A.3    Badran, M.M.4
  • 4
    • 84876479660 scopus 로고    scopus 로고
    • Transdermal delivery of molecules is limited by full epidermis, not just stratum corneum
    • S.N. Andrews, E. Jeong, and M.R. Prausnitz Transdermal delivery of molecules is limited by full epidermis, not just stratum corneum Pharm. Res. 30 2013 1099 1109
    • (2013) Pharm. Res. , vol.30 , pp. 1099-1109
    • Andrews, S.N.1    Jeong, E.2    Prausnitz, M.R.3
  • 5
    • 70349098164 scopus 로고    scopus 로고
    • Effect of size at the nanoscale and bilayer rigidity on skin diffusion of liposomes
    • S. Babu, C. Fan, L. Stepanskiy, J. Uitto, and E. Papazoglou Effect of size at the nanoscale and bilayer rigidity on skin diffusion of liposomes J. Biomed. Mater. Res. A 91 2009 140 148
    • (2009) J. Biomed. Mater. Res. A , vol.91 , pp. 140-148
    • Babu, S.1    Fan, C.2    Stepanskiy, L.3    Uitto, J.4    Papazoglou, E.5
  • 6
    • 0032461067 scopus 로고    scopus 로고
    • Chromatographic indexes on immobilized artificial membranes for the prediction of transdermal transport of drugs
    • F. Barbato, B. Cappello, A. Miro, M.I. La Rotonda, and F. Quaglia Chromatographic indexes on immobilized artificial membranes for the prediction of transdermal transport of drugs Farmaco 53 1998 655 661
    • (1998) Farmaco , vol.53 , pp. 655-661
    • Barbato, F.1    Cappello, B.2    Miro, A.3    La Rotonda, M.I.4    Quaglia, F.5
  • 7
    • 58149191280 scopus 로고    scopus 로고
    • Pig and guinea pig skin as surrogates for human in vitro penetration studies: A quantitative review
    • A.M. Barbero, and H.F. Frasch Pig and guinea pig skin as surrogates for human in vitro penetration studies: a quantitative review Toxicol. In Vitro 23 2009 1 13
    • (2009) Toxicol. in Vitro , vol.23 , pp. 1-13
    • Barbero, A.M.1    Frasch, H.F.2
  • 11
    • 0023926924 scopus 로고
    • Hairless mouse skin is limited as a model for assessing the effects of penetration enhancers in human skin
    • J.R. Bond, and B.W. Barry Hairless mouse skin is limited as a model for assessing the effects of penetration enhancers in human skin J. Invest. Dermatol. 90 1988 810 813
    • (1988) J. Invest. Dermatol. , vol.90 , pp. 810-813
    • Bond, J.R.1    Barry, B.W.2
  • 12
    • 33845308573 scopus 로고    scopus 로고
    • The skin barrier in healthy and diseased state
    • J.A. Bouwstra, and M. Ponec The skin barrier in healthy and diseased state Biochem. Biophys. Acta 1758 2006 2080 2095
    • (2006) Biochem. Biophys. Acta , vol.1758 , pp. 2080-2095
    • Bouwstra, J.A.1    Ponec, M.2
  • 13
    • 0037211560 scopus 로고    scopus 로고
    • Structure of the skin barrier and its modulation by vesicular formulations
    • J.A. Bouwstra, P.L. Honey-Nguyen, G.S. Gooris, and M. Ponec Structure of the skin barrier and its modulation by vesicular formulations Prog. Lipid Res. 42 2003 1 36
    • (2003) Prog. Lipid Res. , vol.42 , pp. 1-36
    • Bouwstra, J.A.1    Honey-Nguyen, P.L.2    Gooris, G.S.3    Ponec, M.4
  • 14
    • 84867492454 scopus 로고    scopus 로고
    • Comparative study of liposomes, transfersomes and ethosomes as carriers for improving topical delivery of celecoxib
    • M. Bragagni, N. Mennini, F. Maestrelli, M. Cirri, and P. Mura Comparative study of liposomes, transfersomes and ethosomes as carriers for improving topical delivery of celecoxib Drug Deliv. 19 2012 354 361
    • (2012) Drug Deliv. , vol.19 , pp. 354-361
    • Bragagni, M.1    Mennini, N.2    Maestrelli, F.3    Cirri, M.4    Mura, P.5
  • 15
    • 84896700937 scopus 로고    scopus 로고
    • Amphotericin B topical microemulsion: Formulation, characterization and evaluation
    • D. Butani, C. Yewale, and A. Misra Amphotericin B topical microemulsion: formulation, characterization and evaluation Colloids Surf. B: Biointerf. 116 2014 351 358
    • (2014) Colloids Surf. B: Biointerf. , vol.116 , pp. 351-358
    • Butani, D.1    Yewale, C.2    Misra, A.3
  • 16
    • 29044441427 scopus 로고    scopus 로고
    • How does the type of vehicle influence the in vitro skin absorption and elimination kinetics of terpenes?
    • K. Cal How does the type of vehicle influence the in vitro skin absorption and elimination kinetics of terpenes? Arch. Dermatol. Res. 297 2006 311 315
    • (2006) Arch. Dermatol. Res. , vol.297 , pp. 311-315
    • Cal, K.1
  • 17
    • 0035237126 scopus 로고    scopus 로고
    • An in vivo method to assess the photostability of UV filters in a sunscreen
    • M. Cambon, N. Issachar, D. Castelli, and C. Robert An in vivo method to assess the photostability of UV filters in a sunscreen J. Cosmet. Sci. 52 2001 1 11
    • (2001) J. Cosmet. Sci. , vol.52 , pp. 1-11
    • Cambon, M.1    Issachar, N.2    Castelli, D.3    Robert, C.4
  • 18
    • 1542268930 scopus 로고    scopus 로고
    • Lipid vesicles and other colloids as drug carriers on the skin
    • G. Cevc Lipid vesicles and other colloids as drug carriers on the skin Adv. Drug Deliv. Rev. 56 2004 675 711
    • (2004) Adv. Drug Deliv. Rev. , vol.56 , pp. 675-711
    • Cevc, G.1
  • 19
    • 84861664005 scopus 로고    scopus 로고
    • Rational design of new product candidates: The next generation of highly deformable bilayer vesicles for noninvasive, targeted therapy
    • G. Cevc Rational design of new product candidates: the next generation of highly deformable bilayer vesicles for noninvasive, targeted therapy J. Control. Release 160 2012 135 146
    • (2012) J. Control. Release , vol.160 , pp. 135-146
    • Cevc, G.1
  • 20
    • 0026508985 scopus 로고
    • Lipid vesicles penetrate into intact skin owing to the transdermal osmotic gradients and hydration force
    • G. Cevc, and G. Blume Lipid vesicles penetrate into intact skin owing to the transdermal osmotic gradients and hydration force Biochim. Biophys. Acta 1104 1992 226 232
    • (1992) Biochim. Biophys. Acta , vol.1104 , pp. 226-232
    • Cevc, G.1    Blume, G.2
  • 21
    • 0035479411 scopus 로고    scopus 로고
    • New, highly efficient formulation of diclofenac for the topical, transdermal administration in ultradeformable drug carriers
    • G. Cevc, and G. Blume New, highly efficient formulation of diclofenac for the topical, transdermal administration in ultradeformable drug carriers Transfersomes. Biochim. Biophys. Acta 1514 2001 191 205
    • (2001) Transfersomes. Biochim. Biophys. Acta , vol.1514 , pp. 191-205
    • Cevc, G.1    Blume, G.2
  • 22
    • 84873526733 scopus 로고    scopus 로고
    • Recent advances in predicting skin permeability of hydrophilic solutes
    • L. Chen, L. Han, and G. Lian Recent advances in predicting skin permeability of hydrophilic solutes Adv. Drug Deliv. Rev. 65 2013 295 305
    • (2013) Adv. Drug Deliv. Rev. , vol.65 , pp. 295-305
    • Chen, L.1    Han, L.2    Lian, G.3
  • 23
    • 80053014951 scopus 로고    scopus 로고
    • Effect of penetration enhancer containing vesicles on the percutaneous delivery of quercetin through new born pig skin
    • M. Chessa, C. Caddeo, D. Valenti, M. Manconi, C. Sinico, and A.M. Fadda Effect of penetration enhancer containing vesicles on the percutaneous delivery of quercetin through new born pig skin Pharmaceutics 3 2011 497 509
    • (2011) Pharmaceutics , vol.3 , pp. 497-509
    • Chessa, M.1    Caddeo, C.2    Valenti, D.3    Manconi, M.4    Sinico, C.5    Fadda, A.M.6
  • 24
    • 84894410296 scopus 로고    scopus 로고
    • Development of a mixed-effect pharmacokinetic model for vehicle modulated in vitro transdermal flux of topically applied penetrants
    • J.T. Chittenden, J.D. Brooksm, and J.E. Riviere Development of a mixed-effect pharmacokinetic model for vehicle modulated in vitro transdermal flux of topically applied penetrants J. Pharm. Sci. 103 2014 1002 1012
    • (2014) J. Pharm. Sci. , vol.103 , pp. 1002-1012
    • Chittenden, J.T.1    Brooksm, J.D.2    Riviere, J.E.3
  • 25
    • 36849043019 scopus 로고    scopus 로고
    • Newborn pig skin as model membrane in in vitro drug permeation studies: A technical note
    • F. Cilurzo, P. Minghetti, and C. Sinico Newborn pig skin as model membrane in in vitro drug permeation studies: a technical note AAPS PharmSciTech 8 2007 A94
    • (2007) AAPS PharmSciTech , vol.8 , pp. A94
    • Cilurzo, F.1    Minghetti, P.2    Sinico, C.3
  • 26
    • 85027920363 scopus 로고    scopus 로고
    • Nanoemulsions (NEs), liposomes (LPs) and solid lipid nanoparticles (SLNs) for retinyl palmitate: Effect on skin permeation
    • B. Clares, A.C. Calpena, A. Parra, G. Abrego, H. Alvarado, J.F. Fangueiro, and E.B. Souto Nanoemulsions (NEs), liposomes (LPs) and solid lipid nanoparticles (SLNs) for retinyl palmitate: effect on skin permeation Int. J. Pharm. 473 2014 591 598
    • (2014) Int. J. Pharm. , vol.473 , pp. 591-598
    • Clares, B.1    Calpena, A.C.2    Parra, A.3    Abrego, G.4    Alvarado, H.5    Fangueiro, J.F.6    Souto, E.B.7
  • 27
    • 34247484067 scopus 로고    scopus 로고
    • Galenics of dermal product - Vehicles, properties and drug release
    • R. Daniels, and U. Knie Galenics of dermal product - vehicles, properties and drug release JDDG 5 2007 369 383
    • (2007) JDDG , vol.5 , pp. 369-383
    • Daniels, R.1    Knie, U.2
  • 28
    • 33646878529 scopus 로고    scopus 로고
    • A novel in vitro percutaneous penetration model: Evaluation of barrier properties with p-aminobenzoic acid and two of its derivatives
    • M. de Jager, W. Groenink, I. Bielsa, R. Guivernau, E. Andersson, N. Angelova, M. Ponec, and J. Bouwstra A novel in vitro percutaneous penetration model: evaluation of barrier properties with p-aminobenzoic acid and two of its derivatives Pharm. Res. 23 2006 951 960
    • (2006) Pharm. Res. , vol.23 , pp. 951-960
    • De Jager, M.1    Groenink, W.2    Bielsa, I.3    Guivernau, R.4    Andersson, E.5    Angelova, N.6    Ponec, M.7    Bouwstra, J.8
  • 29
    • 0035838464 scopus 로고    scopus 로고
    • Topical application of acyclovir-loaded microparticles: Quantification of the drug in porcine skin layers
    • E.G. de Jalón, M.J. Blanco-Príeto, P. Ygartua, and S. Santoyo Topical application of acyclovir-loaded microparticles: quantification of the drug in porcine skin layers J. Control. Release 75 2001 191 197
    • (2001) J. Control. Release , vol.75 , pp. 191-197
    • De Jalón, E.G.1    Blanco-Príeto, M.J.2    Ygartua, P.3    Santoyo, S.4
  • 30
    • 34047252163 scopus 로고    scopus 로고
    • Influence of membrane-solvent-solute interactions on solute permeation in model membranes
    • M. Dias, J. Hadgraft, and M.E. Lane Influence of membrane-solvent-solute interactions on solute permeation in model membranes Int. J. Pharm. 336 2007 108 114
    • (2007) Int. J. Pharm. , vol.336 , pp. 108-114
    • Dias, M.1    Hadgraft, J.2    Lane, M.E.3
  • 31
    • 0026706844 scopus 로고
    • Pig ear skin as an in-vitro model for human skin permeability
    • I.P. Dick, and R.C. Scott Pig ear skin as an in-vitro model for human skin permeability J. Pharm. Pharmacol. 44 1992 640 645
    • (1992) J. Pharm. Pharmacol. , vol.44 , pp. 640-645
    • Dick, I.P.1    Scott, R.C.2
  • 32
    • 0030731485 scopus 로고    scopus 로고
    • The percutaneous absorption and skin distribution of lindane in man. I. in vivo studies
    • I.P. Dick, P.G. Blain, and F.M. Williams The percutaneous absorption and skin distribution of lindane in man. I. In vivo studies Hum. Exp. Toxicol. 16 1997 645 651
    • (1997) Hum. Exp. Toxicol. , vol.16 , pp. 645-651
    • Dick, I.P.1    Blain, P.G.2    Williams, F.M.3
  • 33
    • 84888236652 scopus 로고    scopus 로고
    • 17beta-carboxamide steroids-in vitro prediction of human skin permeability and retention using PAMPA technique
    • V. Dobričić, B. Marković, K. Nikolić, V. Savić, S. Vladimirov, and O. Čudina 17beta-carboxamide steroids-in vitro prediction of human skin permeability and retention using PAMPA technique Eur. J. Pharm. Sci. 52 2014 95 108
    • (2014) Eur. J. Pharm. Sci. , vol.52 , pp. 95-108
    • Dobričić, V.1    Marković, B.2    Nikolić, K.3    Savić, V.4    Vladimirov, S.5    Čudina, O.6
  • 34
    • 40649104527 scopus 로고    scopus 로고
    • Temoporfin-loaded invasomes: Development, characterization and in vitro skin penetration studies
    • N. Dragicevic-Curic, D. Scheglmann, V. Albrecht, and A. Fahr Temoporfin-loaded invasomes: development, characterization and in vitro skin penetration studies J. Control. Release 127 2008 59 69
    • (2008) J. Control. Release , vol.127 , pp. 59-69
    • Dragicevic-Curic, N.1    Scheglmann, D.2    Albrecht, V.3    Fahr, A.4
  • 35
    • 62349100156 scopus 로고    scopus 로고
    • Development of different temoporfin-loaded invasomes-novel nanocarriers of temoporfin: Characterization, stability and in vitro skin penetration studies
    • N. Dragicevic-Curic, D. Scheglmann, V. Albrecht, and A. Fahr Development of different temoporfin-loaded invasomes-novel nanocarriers of temoporfin: characterization, stability and in vitro skin penetration studies Colloids Surf. B Biointerf. 70 2009 198 206
    • (2009) Colloids Surf. B Biointerf. , vol.70 , pp. 198-206
    • Dragicevic-Curic, N.1    Scheglmann, D.2    Albrecht, V.3    Fahr, A.4
  • 37
    • 70649098157 scopus 로고    scopus 로고
    • Surface charged temoporfin-loaded flexible vesicles: In vitro skin penetration studies and stability
    • N. Dragicevic-Curic, S. Gräfe, B. Gitter, S. Winter, and A. Fahr Surface charged temoporfin-loaded flexible vesicles: in vitro skin penetration studies and stability Int. J. Pharm. 384 2010 100 108
    • (2010) Int. J. Pharm. , vol.384 , pp. 100-108
    • Dragicevic-Curic, N.1    Gräfe, S.2    Gitter, B.3    Winter, S.4    Fahr, A.5
  • 38
    • 0036459989 scopus 로고    scopus 로고
    • Comparison of cutaneous bioavailability of cosmetic preparations containing caffeine or alpha-tocopherol applied on human skin models or human skin ex vivo at finite doses
    • F. Dreher, F. Fouchard, C. Patouillet, M. Andrian, J.-T. Simonnet, and F. Benech-Kieffer Comparison of cutaneous bioavailability of cosmetic preparations containing caffeine or alpha-tocopherol applied on human skin models or human skin ex vivo at finite doses Skin Pharmacol. Appl. Skin Physiol. 15 Suppl 1 2002 40 58
    • (2002) Skin Pharmacol. Appl. Skin Physiol. , vol.15 , pp. 40-58
    • Dreher, F.1    Fouchard, F.2    Patouillet, C.3    Andrian, M.4    Simonnet, J.-T.5    Benech-Kieffer, F.6
  • 40
    • 35248888449 scopus 로고    scopus 로고
    • Dermal and transdermal delivery of an anti-psoriatic agent via ethanolic liposomes
    • V. Dubey, D. Mishra, T. Dutta, M. Nahar, D.K. Saraf, and N.K. Jain Dermal and transdermal delivery of an anti-psoriatic agent via ethanolic liposomes J. Control. Release 123 2007 148 154
    • (2007) J. Control. Release , vol.123 , pp. 148-154
    • Dubey, V.1    Mishra, D.2    Dutta, T.3    Nahar, M.4    Saraf, D.K.5    Jain, N.K.6
  • 41
    • 33846854208 scopus 로고    scopus 로고
    • In vivo estimation of stratum corneum thickness from water concentration profiles obtained with Raman spectroscopy
    • M. Egawa, T. Hirao, and M. Takahashi In vivo estimation of stratum corneum thickness from water concentration profiles obtained with Raman spectroscopy Acta Derm. Venereol. 87 2007 4 8
    • (2007) Acta Derm. Venereol. , vol.87 , pp. 4-8
    • Egawa, M.1    Hirao, T.2    Takahashi, M.3
  • 42
    • 84862869361 scopus 로고    scopus 로고
    • Propylene glycol liposomes as a topical delivery system for miconazole nitrate: Comparison with conventional liposomes
    • R.M. Elmoslemany, O.Y. Abdallah, L.K. El-Khordagui, and N.M. Khalafallah Propylene glycol liposomes as a topical delivery system for miconazole nitrate: comparison with conventional liposomes AAPS PharmSciTech 13 2012 723 731
    • (2012) AAPS PharmSciTech , vol.13 , pp. 723-731
    • Elmoslemany, R.M.1    Abdallah, O.Y.2    El-Khordagui, L.K.3    Khalafallah, N.M.4
  • 44
    • 33846905467 scopus 로고    scopus 로고
    • Lipid vesicles for skin delivery of drugs: Reviewing three decades of research
    • M.M.A. Elsayed, O.Y. Abdallah, V.F. Naggar, and N.M. Khalafallah Lipid vesicles for skin delivery of drugs: reviewing three decades of research Int. J. Pharm. 332 2007 1 16
    • (2007) Int. J. Pharm. , vol.332 , pp. 1-16
    • Elsayed, M.M.A.1    Abdallah, O.Y.2    Naggar, V.F.3    Khalafallah, N.M.4
  • 45
    • 84876299390 scopus 로고    scopus 로고
    • New applications of phospholipid vesicle-based permeation assay: Permeation model mimicking skin barrier
    • A. Engesland, M. Skar, T. Hansen, N. Škalko-Basnet, and G.E. Flaten New applications of phospholipid vesicle-based permeation assay: permeation model mimicking skin barrier J. Pharm. Sci. 102 2013 1588 1600
    • (2013) J. Pharm. Sci. , vol.102 , pp. 1588-1600
    • Engesland, A.1    Skar, M.2    Hansen, T.3    Škalko-Basnet, N.4    Flaten, G.E.5
  • 46
    • 84922810636 scopus 로고    scopus 로고
    • PVPA and EpiSkin® in assessment of drug therapies destined for skin administration
    • A. Engesland, N. Škalko-Basnet, and G.E. Flaten PVPA and EpiSkin® in assessment of drug therapies destined for skin administration J. Pharm. Sci. 104 2015 1119 1127
    • (2015) J. Pharm. Sci. , vol.104 , pp. 1119-1127
    • Engesland, A.1    Škalko-Basnet, N.2    Flaten, G.E.3
  • 48
    • 60749111590 scopus 로고    scopus 로고
    • Artificial membrane assays to assess permeability
    • B. Faller Artificial membrane assays to assess permeability Curr. Drug Metabol. 9 2008 886 892
    • (2008) Curr. Drug Metabol. , vol.9 , pp. 886-892
    • Faller, B.1
  • 49
    • 33747128522 scopus 로고    scopus 로고
    • Drug permeability across a phospholipid vesicle based barrier 2. Characterization of barrier structure, storage stability and stability towards pH changes
    • G.E. Flaten, H. Bunjes, K. Luthman, and M. Brandl Drug permeability across a phospholipid vesicle based barrier 2. Characterization of barrier structure, storage stability and stability towards pH changes Eur. J. Pharm. Sci. 28 2006 336 343
    • (2006) Eur. J. Pharm. Sci. , vol.28 , pp. 336-343
    • Flaten, G.E.1    Bunjes, H.2    Luthman, K.3    Brandl, M.4
  • 50
    • 28444480685 scopus 로고    scopus 로고
    • Drug permeability across a phospholipid vesicle based barrier: A novel approach for studying passive diffusion
    • G.E. Flaten, A.B. Dhanikula, K. Luthman, and M. Brandl Drug permeability across a phospholipid vesicle based barrier: a novel approach for studying passive diffusion Eur. J. Pharm. Sci. 27 2006 80 90
    • (2006) Eur. J. Pharm. Sci. , vol.27 , pp. 80-90
    • Flaten, G.E.1    Dhanikula, A.B.2    Luthman, K.3    Brandl, M.4
  • 51
    • 57949097794 scopus 로고    scopus 로고
    • The Phospholipid Vesicle-based Permeability Assay: 5. Development Towards an Automated Procedure for High Throughput Permeability Screening
    • Flaten, G.E., Awoyemi, O., Luthman, K., Brandl, M., Massing, U., 2009. The Phospholipid Vesicle-based Permeability Assay: 5. Development Towards an Automated Procedure for High Throughput Permeability Screening. JALA, pp. 12-21.
    • (2009) JALA , pp. 12-21
    • Flaten, G.E.1    Awoyemi, O.2    Luthman, K.3    Brandl, M.4    Massing, U.5
  • 52
    • 84873525617 scopus 로고    scopus 로고
    • Application of numerical methods for diffusion-based modelling of skin permeation
    • H.F. Frasch, and A.M. Barbero Application of numerical methods for diffusion-based modelling of skin permeation Adv. Drug Deliv. Rev. 65 2013 208 220
    • (2013) Adv. Drug Deliv. Rev. , vol.65 , pp. 208-220
    • Frasch, H.F.1    Barbero, A.M.2
  • 53
    • 84884260517 scopus 로고    scopus 로고
    • Solid lipid nanoparticles of guggul lipid as drug carrier for transdermal drug delivery
    • (Article ID 750690)
    • P.K. Gaur, S. Mishra, and S. Purohit Solid lipid nanoparticles of guggul lipid as drug carrier for transdermal drug delivery BioMed. Res. Int. 2013 (Article ID 750690)
    • (2013) BioMed. Res. Int.
    • Gaur, P.K.1    Mishra, S.2    Purohit, S.3
  • 54
    • 84895869590 scopus 로고    scopus 로고
    • Percutaneous delivery of econazole using microemulsion as vehicle: Formulation, evaluation and vesicle-skin interaction
    • S. Ge, Y. Lin, H. Lu, Q. Li, J. He, B. Chen, C. Wu, and Y. Xu Percutaneous delivery of econazole using microemulsion as vehicle: formulation, evaluation and vesicle-skin interaction Int. J. Pharm. 465 2014 120 131
    • (2014) Int. J. Pharm. , vol.465 , pp. 120-131
    • Ge, S.1    Lin, Y.2    Lu, H.3    Li, Q.4    He, J.5    Chen, B.6    Wu, C.7    Xu, Y.8
  • 57
    • 35349002202 scopus 로고    scopus 로고
    • Transdermal skin delivery: Predictions for humans from in vivo, ex vivo and animal models
    • B. Godin, and E. Touitou Transdermal skin delivery: predictions for humans from in vivo, ex vivo and animal models Adv. Drug Deliv. Rev. 59 2007 1152 1161
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , pp. 1152-1161
    • Godin, B.1    Touitou, E.2
  • 58
    • 84897766091 scopus 로고    scopus 로고
    • Lipid nanoparticles for topical and transdermal application for alopecia treatment: Development, physicochemical characterization, and in vitro release and penetration studies
    • M.J. Gomes, S. Martins, D. Ferreira, M.A. Segundo, and S. Reis Lipid nanoparticles for topical and transdermal application for alopecia treatment: development, physicochemical characterization, and in vitro release and penetration studies Int. J. Nanomed. 9 2014 1231 1242
    • (2014) Int. J. Nanomed. , vol.9 , pp. 1231-1242
    • Gomes, M.J.1    Martins, S.2    Ferreira, D.3    Segundo, M.A.4    Reis, S.5
  • 60
    • 52049116882 scopus 로고    scopus 로고
    • Two new methods for preparing a unique stratum corneum substitute
    • D. Groen, G.S. Gooris, M. Ponec, and J.A. Bouwstra Two new methods for preparing a unique stratum corneum substitute Biochem. Biophys. Acta 1778 2008 2421 2429
    • (2008) Biochem. Biophys. Acta , vol.1778 , pp. 2421-2429
    • Groen, D.1    Gooris, G.S.2    Ponec, M.3    Bouwstra, J.A.4
  • 61
    • 80054966314 scopus 로고    scopus 로고
    • Investogating the barrier function of skin lipid models with varying compositions
    • D. Groen, D.S. Poole, G.S. Gooris, and J.A. Bouwstra Investogating the barrier function of skin lipid models with varying compositions Eur. J. Pharm. Biopharm. 79 2011 334 342
    • (2011) Eur. J. Pharm. Biopharm. , vol.79 , pp. 334-342
    • Groen, D.1    Poole, D.S.2    Gooris, G.S.3    Bouwstra, J.A.4
  • 62
    • 0035859979 scopus 로고    scopus 로고
    • Skin, the final frontier
    • J. Hadgraft Skin, the final frontier Int. J. Pharm. 224 2001 1 18
    • (2001) Int. J. Pharm. , vol.224 , pp. 1-18
    • Hadgraft, J.1
  • 63
    • 0028577839 scopus 로고
    • The selection and use of natural and synthetic membranes for in vitro diffusion experiments
    • J.M. Haigh, and E.W. Smith The selection and use of natural and synthetic membranes for in vitro diffusion experiments Eur. J. Pharm. Sci. 2 1994 311 330
    • (1994) Eur. J. Pharm. Sci. , vol.2 , pp. 311-330
    • Haigh, J.M.1    Smith, E.W.2
  • 64
    • 84860850016 scopus 로고    scopus 로고
    • Polyamide nanocapsules and nano-emulsions containing Parsol(R) MCX and Parsol(R) 1789: In vitro release, ex vivo skin penetration and photo-stability studies
    • I. Hanno, C. Anselmi, and K. Bouchemal Polyamide nanocapsules and nano-emulsions containing Parsol(R) MCX and Parsol(R) 1789: in vitro release, ex vivo skin penetration and photo-stability studies Pharm. Res. 29 2012 559 573
    • (2012) Pharm. Res. , vol.29 , pp. 559-573
    • Hanno, I.1    Anselmi, C.2    Bouchemal, K.3
  • 66
    • 67349280382 scopus 로고    scopus 로고
    • Potential pitfalls in skin permeation experiments: Influence of experimental factors and subsequent data evaluation
    • A. Henning, U.F. Schaefer, and D. Neumann Potential pitfalls in skin permeation experiments: influence of experimental factors and subsequent data evaluation Eur. J. Pharm. Biopharm. 72 2009 324 331
    • (2009) Eur. J. Pharm. Biopharm. , vol.72 , pp. 324-331
    • Henning, A.1    Schaefer, U.F.2    Neumann, D.3
  • 67
    • 84885949071 scopus 로고    scopus 로고
    • Evaluation of the suitability of chromatographic systems to predict human skin permeation of neutral compounds
    • M. Hidalgo-Rodríguez, S. Soriano-Meseguer, E. Fuguet, C. Ráfols, and M. Roses Evaluation of the suitability of chromatographic systems to predict human skin permeation of neutral compounds Eur. J. Pharm. Sci. 50 2013 557 568
    • (2013) Eur. J. Pharm. Sci. , vol.50 , pp. 557-568
    • Hidalgo-Rodríguez, M.1    Soriano-Meseguer, S.2    Fuguet, E.3    Ráfols, C.4    Roses, M.5
  • 68
    • 0025173497 scopus 로고
    • Use of shed snake skin as a model membrane for in vitro percutaneous penetration studies: Comparison with human skin
    • T. Itoh, J. Xia, R. Magavi, T. Nishihata, and J.H. Rytting Use of shed snake skin as a model membrane for in vitro percutaneous penetration studies: comparison with human skin Pharm. Res. 7 1990 1042 1047
    • (1990) Pharm. Res. , vol.7 , pp. 1042-1047
    • Itoh, T.1    Xia, J.2    Magavi, R.3    Nishihata, T.4    Rytting, J.H.5
  • 70
    • 84873523117 scopus 로고    scopus 로고
    • Modeling the human skin barrier - Towards a better understanding of dermal absorption
    • O.G. Jepps, Y. Dancik, Y.G. Anissimov, and M.S. Roberts Modeling the human skin barrier - towards a better understanding of dermal absorption Adv. Drug Deliv. Rev. 65 2013 152 168
    • (2013) Adv. Drug Deliv. Rev. , vol.65 , pp. 152-168
    • Jepps, O.G.1    Dancik, Y.2    Anissimov, Y.G.3    Roberts, M.S.4
  • 71
    • 84896051513 scopus 로고    scopus 로고
    • Charge-mediated topical delivery of plasmid DNA with cationic lipid nanoparticles to the skin
    • S.-E. Jin, and C.-K. Kim Charge-mediated topical delivery of plasmid DNA with cationic lipid nanoparticles to the skin Colloids Surf. B Biointerf. 116 2014 582 590
    • (2014) Colloids Surf. B Biointerf. , vol.116 , pp. 582-590
    • Jin, S.-E.1    Kim, C.-K.2
  • 72
    • 84856534367 scopus 로고    scopus 로고
    • Physicochemical properties and skin permeation of Span 60/Tween 60 niosomes of ellagic acid
    • V.B. Junyaprasert, P. Singhsa, J. Suksiriworapong, and D. Chantasart Physicochemical properties and skin permeation of Span 60/Tween 60 niosomes of ellagic acid Int. J. Pharm. 423 2012 303 311
    • (2012) Int. J. Pharm. , vol.423 , pp. 303-311
    • Junyaprasert, V.B.1    Singhsa, P.2    Suksiriworapong, J.3    Chantasart, D.4
  • 73
    • 0032568397 scopus 로고    scopus 로고
    • Physicochemical high throughput screening: Parallel artificial membrane permeation assay in the description of passive absorption processes
    • M. Kansy, F. Senner, and K. Gubernator Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes J. Med. Chem. 41 1998 1007 1010
    • (1998) J. Med. Chem. , vol.41 , pp. 1007-1010
    • Kansy, M.1    Senner, F.2    Gubernator, K.3
  • 74
    • 26844525852 scopus 로고    scopus 로고
    • In vitro permeation of diclofenac sodium from novel microemulsion formulations through rabbit skin
    • G. Kantarci, I. Ozgüngey, H.Y. Karasulu, T. Güneri, and G. Başdemir In vitro permeation of diclofenac sodium from novel microemulsion formulations through rabbit skin Drug Develop. Res. 65 2005 17 25
    • (2005) Drug Develop. Res. , vol.65 , pp. 17-25
    • Kantarci, G.1    Ozgüngey, I.2    Karasulu, H.Y.3    Güneri, T.4    Başdemir, G.5
  • 75
    • 84885952959 scopus 로고    scopus 로고
    • Assessing vehicle effects on skin absorption using artificial membrane assays
    • D. Karadzovska, and J.E. Riviere Assessing vehicle effects on skin absorption using artificial membrane assays Eur. J. Pharm. Sci. 50 2013 569 576
    • (2013) Eur. J. Pharm. Sci. , vol.50 , pp. 569-576
    • Karadzovska, D.1    Riviere, J.E.2
  • 77
    • 84883637791 scopus 로고    scopus 로고
    • Preparation and evaluation of solid lipid nanoparticles based nanogel for dermal delivery of meloxicam
    • S. Khurana, P.M.S. Bedi, and N.K. Jain Preparation and evaluation of solid lipid nanoparticles based nanogel for dermal delivery of meloxicam Chem. Phys. Lipids 175-176 2013 65 72
    • (2013) Chem. Phys. Lipids , vol.175-176 , pp. 65-72
    • Khurana, S.1    Bedi, P.M.S.2    Jain, N.K.3
  • 78
    • 84866011206 scopus 로고    scopus 로고
    • Measurement of skin permeation/penetration of nanoparticles for their safety evaluation
    • E. Kimura, Y. Kawano, H. Todo, Y. Ikarashi, and K. Sugibayashi Measurement of skin permeation/penetration of nanoparticles for their safety evaluation Biol. Pharm. Bull. 35 2012 1476 1486
    • (2012) Biol. Pharm. Bull. , vol.35 , pp. 1476-1486
    • Kimura, E.1    Kawano, Y.2    Todo, H.3    Ikarashi, Y.4    Sugibayashi, K.5
  • 80
    • 79960562781 scopus 로고    scopus 로고
    • Investigations on skin permeation of hyaluronic acid based nanoemulsion as transdermal carrier
    • M. Kong, X.G. Chen, D.K. Kweon, and H.J. Park Investigations on skin permeation of hyaluronic acid based nanoemulsion as transdermal carrier Carbohyd. Polym. 86 2011 837 843
    • (2011) Carbohyd. Polym. , vol.86 , pp. 837-843
    • Kong, M.1    Chen, X.G.2    Kweon, D.K.3    Park, H.J.4
  • 81
    • 84875805259 scopus 로고    scopus 로고
    • Setup for investigating gold nanoparticle penetration through reconstructed skin and comparison to published human skin data
    • H.I. Labouta, S. Thude, and M. Schneider Setup for investigating gold nanoparticle penetration through reconstructed skin and comparison to published human skin data J. Biomed. Opt. 18 2013 061218
    • (2013) J. Biomed. Opt. , vol.18 , pp. 061218
    • Labouta, H.I.1    Thude, S.2    Schneider, M.3
  • 83
    • 76749161781 scopus 로고    scopus 로고
    • Which skin model is the most appropriate for the investigation of topically applied substances into the hair follicles?
    • Lademann Which skin model is the most appropriate for the investigation of topically applied substances into the hair follicles? Skin Pharmacol. Physiol. 23 2010 47 52
    • (2010) Skin Pharmacol. Physiol. , vol.23 , pp. 47-52
    • Lademann1
  • 84
    • 84893382314 scopus 로고    scopus 로고
    • Advanced progress of microencapsulation technologies: In vivo and in vitro models for studying oral and transdermal drug deliveries
    • P.L. Lam, and R. Gambari Advanced progress of microencapsulation technologies: in vivo and in vitro models for studying oral and transdermal drug deliveries J. Control. Release 178 2014 25 45
    • (2014) J. Control. Release , vol.178 , pp. 25-45
    • Lam, P.L.1    Gambari, R.2
  • 85
    • 72149102463 scopus 로고    scopus 로고
    • Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay
    • P.H. Lee, R. Conradi, and V. Shanmugasundram Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay Bioorg. Med. Chem. Lett. 20 2010 69 73
    • (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 69-73
    • Lee, P.H.1    Conradi, R.2    Shanmugasundram, V.3
  • 86
    • 33845314297 scopus 로고    scopus 로고
    • Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery
    • J. Liu, W. Hu, H. Chen, Q. Ni, H. Xu, and X. Yang Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery Int. J. Pharm. 328 2007 191 195
    • (2007) Int. J. Pharm. , vol.328 , pp. 191-195
    • Liu, J.1    Hu, W.2    Chen, H.3    Ni, Q.4    Xu, H.5    Yang, X.6
  • 87
    • 33750492253 scopus 로고    scopus 로고
    • Development and evaluation of an artificial membrane for determination of drug availability
    • T. Loftsson, F. Konradsdottir, and M. Masson Development and evaluation of an artificial membrane for determination of drug availability Int. J. Pharm. 326 2006 60 68
    • (2006) Int. J. Pharm. , vol.326 , pp. 60-68
    • Loftsson, T.1    Konradsdottir, F.2    Masson, M.3
  • 88
    • 64149094878 scopus 로고    scopus 로고
    • Development and evaluation of penciclovir-loaded solid lipid nanoparticles for topical delivery
    • Q. Lv, A. Yu, Y. Xi, H. Li, Z. Song, J. Cui, F. Cao, and G. Zhai Development and evaluation of penciclovir-loaded solid lipid nanoparticles for topical delivery Int. J. Pharm. 372 2009 191 198
    • (2009) Int. J. Pharm. , vol.372 , pp. 191-198
    • Lv, Q.1    Yu, A.2    Xi, Y.3    Li, H.4    Song, Z.5    Cui, J.6    Cao, F.7    Zhai, G.8
  • 89
    • 84908518364 scopus 로고    scopus 로고
    • Development of novel diolein-niosomes for cutaneous delivery of tretinoin: Influence of formulation and in vitro assessment
    • M.L. Manca, M. Manconi, A. Nacher, C. Carbone, D. Valenti, A.M. Maccioni, C. Sinico, and A.M. Fadda Development of novel diolein-niosomes for cutaneous delivery of tretinoin: influence of formulation and in vitro assessment Int. J. Pharm. 477 2014 176 186
    • (2014) Int. J. Pharm. , vol.477 , pp. 176-186
    • Manca, M.L.1    Manconi, M.2    Nacher, A.3    Carbone, C.4    Valenti, D.5    Maccioni, A.M.6    Sinico, C.7    Fadda, A.M.8
  • 90
    • 79953161603 scopus 로고    scopus 로고
    • Ex vivo skin delivery of diclofenac by transcutol containing liposomes and suggested mechanism of vesicle-skin interaction
    • M. Manconi, C. Caddeo, C. Sinico, D. Valenti, M.C. Mostallino, G. Biggio, and A.M. Fadda Ex vivo skin delivery of diclofenac by transcutol containing liposomes and suggested mechanism of vesicle-skin interaction Eur. J. Pharm. Biopharm. 78 2011 27 35
    • (2011) Eur. J. Pharm. Biopharm. , vol.78 , pp. 27-35
    • Manconi, M.1    Caddeo, C.2    Sinico, C.3    Valenti, D.4    Mostallino, M.C.5    Biggio, G.6    Fadda, A.M.7
  • 91
    • 79957494277 scopus 로고    scopus 로고
    • Penetration enhancer containing vesicles as carriers for dermal delivery of tretinoin
    • M. Manconi, C. Sinico, C. Caddeo, A.O. Vila, D. Valenti, and A.M. Fadda Penetration enhancer containing vesicles as carriers for dermal delivery of tretinoin Int. J. Pharm. 412 2011 37 46
    • (2011) Int. J. Pharm. , vol.412 , pp. 37-46
    • Manconi, M.1    Sinico, C.2    Caddeo, C.3    Vila, A.O.4    Valenti, D.5    Fadda, A.M.6
  • 92
    • 84892592662 scopus 로고    scopus 로고
    • Design, synthesis of novel lipids as chemical permeation enhancers and development of nanoparticle system for transdermal drug delivery
    • S. Marepally, C.H.A. Boakye, P.P. Shah, J.R. Etukala, A. Vemuri, and M. Singh Design, synthesis of novel lipids as chemical permeation enhancers and development of nanoparticle system for transdermal drug delivery PLoS One 8 2013
    • (2013) PLoS One , vol.8
    • Marepally, S.1    Boakye, C.H.A.2    Shah, P.P.3    Etukala, J.R.4    Vemuri, A.5    Singh, M.6
  • 93
    • 84873598560 scopus 로고    scopus 로고
    • Self-assembled nanoparticles of PLGA-conjugated glucosamine as a sustained transdermal drug delivery vehicle
    • M. Marimuthu, D. Bennet, and S. Kim Self-assembled nanoparticles of PLGA-conjugated glucosamine as a sustained transdermal drug delivery vehicle Polym. J. 45 2013 202 209
    • (2013) Polym. J. , vol.45 , pp. 202-209
    • Marimuthu, M.1    Bennet, D.2    Kim, S.3
  • 94
    • 84856199554 scopus 로고    scopus 로고
    • A PAMPA assay as fast predictive model of passive human skin permeability of new synthesized corticosteroid C-21 esters
    • B.D. Markovic, S.M. Vladimirov, O.A. Cudina, J.V. Odovic, and K.D. Karljikovic-Rajic A PAMPA assay as fast predictive model of passive human skin permeability of new synthesized corticosteroid C-21 esters Molecules 17 2012 480 491
    • (2012) Molecules , vol.17 , pp. 480-491
    • Markovic, B.D.1    Vladimirov, S.M.2    Cudina, O.A.3    Odovic, J.V.4    Karljikovic-Rajic, K.D.5
  • 96
    • 84881592187 scopus 로고    scopus 로고
    • Enhanced transdermal bioavailability of testosterone propionate via surfactant-modified ethosomes
    • S. Meng, Z. Chen, L. Yang, W. Zhang, D. Liu, J. Guo, Y. Guan, and J. Li Enhanced transdermal bioavailability of testosterone propionate via surfactant-modified ethosomes Int. J. Nanomed. 8 2013 3051 3060
    • (2013) Int. J. Nanomed. , vol.8 , pp. 3051-3060
    • Meng, S.1    Chen, Z.2    Yang, L.3    Zhang, W.4    Liu, D.5    Guo, J.6    Guan, Y.7    Li, J.8
  • 97
    • 84864288846 scopus 로고    scopus 로고
    • The structure and function of the stratum corneum
    • G.K. Menon, G.W. Cleary, and M.E. Lane The structure and function of the stratum corneum Int. J. Pharm. 435 2012 3 9
    • (2012) Int. J. Pharm. , vol.435 , pp. 3-9
    • Menon, G.K.1    Cleary, G.W.2    Lane, M.E.3
  • 98
    • 33745269809 scopus 로고    scopus 로고
    • A note on integumental (1 - - >3)(1 - - >6)beta-D-glucan permeation, using the porcine ear skin model
    • W. Meyer, B. Schönnagel, and L.G. Fleischer A note on integumental (1 - - >3)(1 - - >6)beta-D-glucan permeation, using the porcine ear skin model J. Cosmet. Dermatol. 5 2006 130 134
    • (2006) J. Cosmet. Dermatol. , vol.5 , pp. 130-134
    • Meyer, W.1    Schönnagel, B.2    Fleischer, L.G.3
  • 99
    • 84949117010 scopus 로고    scopus 로고
    • Development of a membrane impregnated with a poly(dimethylsiloxane)/poly(ethylene glycol) copolymer for a high-throughput screening of the permeability of drugs, cosmetics, and other chemicals across the human skin
    • R. Miki, Y. Ichitsuka, T. Yamada, S. Kimura, Y. Egawa, T. Seki, K. Juni, H. Ueda, and Y. Morimoto Development of a membrane impregnated with a poly(dimethylsiloxane)/poly(ethylene glycol) copolymer for a high-throughput screening of the permeability of drugs, cosmetics, and other chemicals across the human skin Eur. J. Pharm. Sci. 66 2015 41 49
    • (2015) Eur. J. Pharm. Sci. , vol.66 , pp. 41-49
    • Miki, R.1    Ichitsuka, Y.2    Yamada, T.3    Kimura, S.4    Egawa, Y.5    Seki, T.6    Juni, K.7    Ueda, H.8    Morimoto, Y.9
  • 102
    • 69549110945 scopus 로고    scopus 로고
    • Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil
    • S. Mura, M. Manconi, C. Sinico, D. Valenti, and A.M. Fadda Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil Int. J. Pharm. 380 2009 72 79
    • (2009) Int. J. Pharm. , vol.380 , pp. 72-79
    • Mura, S.1    Manconi, M.2    Sinico, C.3    Valenti, D.4    Fadda, A.M.5
  • 104
    • 84873526908 scopus 로고    scopus 로고
    • Detailed modeling of skin penetration - An overview
    • A. Naegel, M. Heisig, and G. Wittum Detailed modeling of skin penetration - an overview Adv. Drug. Deliver. Rev. 65 2013 191 207
    • (2013) Adv. Drug. Deliver. Rev. , vol.65 , pp. 191-207
    • Naegel, A.1    Heisig, M.2    Wittum, G.3
  • 105
    • 84876680414 scopus 로고    scopus 로고
    • Influence of drug content, type of semi-solid vehicle and rheological properties on the skin penetration of the model drug fludrocortisone acetate
    • C. Nagelreiter, S. Raffeiner, C. Geyerhofer, V. Klang, and C. Valenta Influence of drug content, type of semi-solid vehicle and rheological properties on the skin penetration of the model drug fludrocortisone acetate Int. J. Pharm. 448 2013 305 312
    • (2013) Int. J. Pharm. , vol.448 , pp. 305-312
    • Nagelreiter, C.1    Raffeiner, S.2    Geyerhofer, C.3    Klang, V.4    Valenta, C.5
  • 106
    • 0014816820 scopus 로고
    • Release, uptake, and permeation behavior of salicylic acid in ointment bases
    • M. Nakano, and N.K. Patel Release, uptake, and permeation behavior of salicylic acid in ointment bases J. Pharm. Sci. 59 1970 985 988
    • (1970) J. Pharm. Sci. , vol.59 , pp. 985-988
    • Nakano, M.1    Patel, N.K.2
  • 107
    • 84862826862 scopus 로고    scopus 로고
    • Tocopheryl acetate nanoemulsions stabilized with lipid-polymer hybrid emulsifiers for effective skin delivery
    • Y.S. Nam, J.-W. Kim, J.Y. Park, J. Shim, J.S. Lee, and S.H. Han Tocopheryl acetate nanoemulsions stabilized with lipid-polymer hybrid emulsifiers for effective skin delivery Colloids Surf. B Biointerf. 94 2012 51 57
    • (2012) Colloids Surf. B Biointerf. , vol.94 , pp. 51-57
    • Nam, Y.S.1    Kim, J.-W.2    Park, J.Y.3    Shim, J.4    Lee, J.S.5    Han, S.H.6
  • 108
    • 20444375525 scopus 로고    scopus 로고
    • The human epidermis models EpiSkin, SkinEthic and EpiDerm: An evaluation of morphology and their suitability for testing phototoxicity, irritancy, corrosivity, and substance transport
    • F. Netzlaff, C.-M. Lehr, P.W. Wertz, and U.F. Schaefer The human epidermis models EpiSkin, SkinEthic and EpiDerm: an evaluation of morphology and their suitability for testing phototoxicity, irritancy, corrosivity, and substance transport Eur. J. Pharm. Biopharm. 60 2005 167 178
    • (2005) Eur. J. Pharm. Biopharm. , vol.60 , pp. 167-178
    • Netzlaff, F.1    Lehr, C.-M.2    Wertz, P.W.3    Schaefer, U.F.4
  • 109
    • 33645890848 scopus 로고    scopus 로고
    • TEWL measurements as a routine for evaluating the integrity of epidermis sheets in static Franz type diffusion cells in vitro. Limitations shown by transport data testing
    • F. Netzlaff, K.H. Kostka, C.M. Lehr, and U.F. Schaefer TEWL measurements as a routine for evaluating the integrity of epidermis sheets in static Franz type diffusion cells in vitro. Limitations shown by transport data testing Eur. J. Pharm. Biopharm. 63 2006 44 50
    • (2006) Eur. J. Pharm. Biopharm. , vol.63 , pp. 44-50
    • Netzlaff, F.1    Kostka, K.H.2    Lehr, C.M.3    Schaefer, U.F.4
  • 111
    • 78649907180 scopus 로고    scopus 로고
    • Validation of a static Franz diffusion cell system for in vitro permeation studies
    • S.-F. Ng, J.J. Rouse, F.D. Sanderson, V. Meidan, and G.M. 2 Eccleston Validation of a static Franz diffusion cell system for in vitro permeation studies AAPS PharmSciTech 11 2010 1432 1441
    • (2010) AAPS PharmSciTech , vol.11 , pp. 1432-1441
    • Ng, S.-F.1    Rouse, J.J.2    Sanderson, F.D.3    Meidan, V.4    Eccleston, G.M.5
  • 112
    • 39749175491 scopus 로고    scopus 로고
    • Evaluation of simultaneous permeation and metabolism of methyl nicotinate in human, snake, and shed snake skin
    • T. Ngawhirunpat, P. Opanasopit, T. Rojanarata, S. Panomsuk, and L. Chanchome Evaluation of simultaneous permeation and metabolism of methyl nicotinate in human, snake, and shed snake skin Pharm. Dev. Technol. 13 2008 75 83
    • (2008) Pharm. Dev. Technol. , vol.13 , pp. 75-83
    • Ngawhirunpat, T.1    Opanasopit, P.2    Rojanarata, T.3    Panomsuk, S.4    Chanchome, L.5
  • 113
    • 84908544041 scopus 로고    scopus 로고
    • Development of artemether-loaded nanostructured lipid carrier (NLC) formulation for topical application
    • P.O. Nnamani, S. Hansen, M. Windbergs, and C.-M. Lehr Development of artemether-loaded nanostructured lipid carrier (NLC) formulation for topical application Int. J. Pharm. 477 2014 208 217
    • (2014) Int. J. Pharm. , vol.477 , pp. 208-217
    • Nnamani, P.O.1    Hansen, S.2    Windbergs, M.3    Lehr, C.-M.4
  • 114
    • 84861097338 scopus 로고    scopus 로고
    • Characterization of lipid model membranes designed for studying impact of ceramide species on drug diffusion and penetration
    • M. Ochalek, S. Heissler, J. Wohlrab, and R.H.H. Neubert Characterization of lipid model membranes designed for studying impact of ceramide species on drug diffusion and penetration Eur. J. Pharm. Biopharm. 81 2012 113 120
    • (2012) Eur. J. Pharm. Biopharm. , vol.81 , pp. 113-120
    • Ochalek, M.1    Heissler, S.2    Wohlrab, J.3    Neubert, R.H.H.4
  • 115
    • 84865294045 scopus 로고    scopus 로고
    • SC lipid model membranes designed for studying impact of ceramide species on drug diffusion and permeation, Part III: Influence of penetration enhancer on diffusion and permeation of model drugs
    • M. Ochalek, H. Podhaisky, H.-H. Ruettinger, R.H.H. Neubert, and J. Wohlrab SC lipid model membranes designed for studying impact of ceramide species on drug diffusion and permeation, Part III: Influence of penetration enhancer on diffusion and permeation of model drugs Int. J. Pharm. 436 2012 206 213
    • (2012) Int. J. Pharm. , vol.436 , pp. 206-213
    • Ochalek, M.1    Podhaisky, H.2    Ruettinger, H.-H.3    Neubert, R.H.H.4    Wohlrab, J.5
  • 116
    • 84929705251 scopus 로고    scopus 로고
    • OECD, 2004. Guidance document for the conduct of skin absorption studies number 28. In: OECD Series on Testing and Assessment.
    • OECD, 2004. Guidance document for the conduct of skin absorption studies number 28. In: OECD Series on Testing and Assessment.
  • 117
    • 84866999771 scopus 로고    scopus 로고
    • Structural analysis of "flexible" liposome formulations: New insights into the skin-penetrating ability of soft nanostructures
    • O.A. Ogunsola, M.E. Kraeling, S. Zhong, D.J. Pochan, R.L. Bronaugh, and S.L. Raghavan Structural analysis of "flexible" liposome formulations: new insights into the skin-penetrating ability of soft nanostructures Soft Matter 8 2012 10226 10232
    • (2012) Soft Matter , vol.8 , pp. 10226-10232
    • Ogunsola, O.A.1    Kraeling, M.E.2    Zhong, S.3    Pochan, D.J.4    Bronaugh, R.L.5    Raghavan, S.L.6
  • 118
    • 77953357147 scopus 로고    scopus 로고
    • Alcohol enhanced permeation in model membranes. Part I. Thermodynamic and kinetic analyses of membrane permeation
    • G. Oliveira, A.E. Beezer, J. Hadgraft, and M.E. Lane Alcohol enhanced permeation in model membranes. Part I. Thermodynamic and kinetic analyses of membrane permeation Int. J. Pharm. 393 2010 61 67
    • (2010) Int. J. Pharm. , vol.393 , pp. 61-67
    • Oliveira, G.1    Beezer, A.E.2    Hadgraft, J.3    Lane, M.E.4
  • 119
    • 80054693636 scopus 로고    scopus 로고
    • Alcohol enhanced permeation in model membranes. Part II. Thermodynamic analysis of membrane partitioning
    • G. Oliveira, A.E. Beezer, J. Hadgraft, and M.E. Lane Alcohol enhanced permeation in model membranes. Part II. Thermodynamic analysis of membrane partitioning Int. J. Pharm. 420 2011 216 222
    • (2011) Int. J. Pharm. , vol.420 , pp. 216-222
    • Oliveira, G.1    Beezer, A.E.2    Hadgraft, J.3    Lane, M.E.4
  • 120
    • 84868211539 scopus 로고    scopus 로고
    • The role of vehicle interactions on permeation of an active through model membranes and human skin
    • G. Oliveira, J. Hadgraft, and M.E. Lane The role of vehicle interactions on permeation of an active through model membranes and human skin Int. J. Cosmet. Sci. 34 2012 536 545
    • (2012) Int. J. Cosmet. Sci. , vol.34 , pp. 536-545
    • Oliveira, G.1    Hadgraft, J.2    Lane, M.E.3
  • 121
    • 33745642435 scopus 로고    scopus 로고
    • Parallel artificial membrane permeability assay: A new membrane for the fast prediction of passive human skin permeability
    • G. Ottaviani, S. Martel, and P.A. Carrupt Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability J. Med. Chem. 49 2006 3948 3954
    • (2006) J. Med. Chem. , vol.49 , pp. 3948-3954
    • Ottaviani, G.1    Martel, S.2    Carrupt, P.A.3
  • 122
    • 33847416530 scopus 로고    scopus 로고
    • In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities
    • G. Ottaviani, S. Martel, and P.-A. Carrupt In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities J. Med. Chem. 50 2007 742 748
    • (2007) J. Med. Chem. , vol.50 , pp. 742-748
    • Ottaviani, G.1    Martel, S.2    Carrupt, P.-A.3
  • 123
    • 84911491772 scopus 로고    scopus 로고
    • Liposomes for (trans)dermal drug delivery: The skin-PVPA as a novel in vitro stratum corneum model in formulation development
    • Z. Palac, A. Engesland, G.E. Flaten, N. Škalko-Basnet, J. Filipović-Grčić, and Ž. Vanić Liposomes for (trans)dermal drug delivery: the skin-PVPA as a novel in vitro stratum corneum model in formulation development J. Liposome Res. 24 2014 313 322
    • (2014) J. Liposome Res. , vol.24 , pp. 313-322
    • Palac, Z.1    Engesland, A.2    Flaten, G.E.3    Škalko-Basnet, N.4    Filipović-Grčić, J.5    Vanić Ž.6
  • 124
    • 84879057379 scopus 로고    scopus 로고
    • Preparation of quercetin and rutin-loaded ceramide liposomes and drug-releasing effect in liposome-in-hydrogel complex system
    • S.N. Park, M.H. Lee, S.J. Kim, and E.R. Yu Preparation of quercetin and rutin-loaded ceramide liposomes and drug-releasing effect in liposome-in-hydrogel complex system Biochem. Biophys. Res. Commun. 435 2013 361 366
    • (2013) Biochem. Biophys. Res. Commun. , vol.435 , pp. 361-366
    • Park, S.N.1    Lee, M.H.2    Kim, S.J.3    Yu, E.R.4
  • 125
    • 70449520102 scopus 로고    scopus 로고
    • Formulation and evaluation of lidocaine lipid nanosystems for dermal delivery
    • P. Pathak, and M. Nagarsenker Formulation and evaluation of lidocaine lipid nanosystems for dermal delivery AAPS PharmSciTech 10 2009 985 992
    • (2009) AAPS PharmSciTech , vol.10 , pp. 985-992
    • Pathak, P.1    Nagarsenker, M.2
  • 127
    • 84877858300 scopus 로고    scopus 로고
    • Comparative study of the skin tolerability of hand disinfectants using the BUS model
    • W. Pittermann, C. Hildebrandt, A. Prinz, S. Lemanski, and M. Keitzmann Comparative study of the skin tolerability of hand disinfectants using the BUS model Hyg. Med. 38 2013 134 141
    • (2013) Hyg. Med. , vol.38 , pp. 134-141
    • Pittermann, W.1    Hildebrandt, C.2    Prinz, A.3    Lemanski, S.4    Keitzmann, M.5
  • 128
    • 0026472940 scopus 로고
    • In vitro cultured human skin cells as alternatives to animals for skin irritancy screening
    • M. Ponec In vitro cultured human skin cells as alternatives to animals for skin irritancy screening Int. J. Cosmet. Sci. 14 1992 245 264
    • (1992) Int. J. Cosmet. Sci. , vol.14 , pp. 245-264
    • Ponec, M.1
  • 129
    • 80052265433 scopus 로고    scopus 로고
    • Development and evaluation of colloidal modified nanolipid carrier: Application to topical delivery of tacrolimus
    • P.V. Pople, and K.K. Singh Development and evaluation of colloidal modified nanolipid carrier: application to topical delivery of tacrolimus Eur. J. Pharm. Biopharm. 79 2011 82 94
    • (2011) Eur. J. Pharm. Biopharm. , vol.79 , pp. 82-94
    • Pople, P.V.1    Singh, K.K.2
  • 131
    • 0035964456 scopus 로고    scopus 로고
    • Lipid extraction and transport of hydrophilic solutes through porcine epidermis
    • S.K. Rastogi, and J. Singh Lipid extraction and transport of hydrophilic solutes through porcine epidermis Int. J. Pharm. 225 2001 75 82
    • (2001) Int. J. Pharm. , vol.225 , pp. 75-82
    • Rastogi, S.K.1    Singh, J.2
  • 132
    • 0025141213 scopus 로고
    • Shed snake skin and hairless mouse skin as model membranes for human skin during permeation studies
    • P.C. Rigg, and B.W. Barry Shed snake skin and hairless mouse skin as model membranes for human skin during permeation studies J. Invest. Dermatol. 94 1990 235 240
    • (1990) J. Invest. Dermatol. , vol.94 , pp. 235-240
    • Rigg, P.C.1    Barry, B.W.2
  • 133
    • 84896392279 scopus 로고    scopus 로고
    • Controlled penetration of ceramides into and across the stratum corneum using various types of microemulsions and formulation associated toxicity studies
    • F.F. Sahle, J. Wohlrab, and R.H.H. Neubert Controlled penetration of ceramides into and across the stratum corneum using various types of microemulsions and formulation associated toxicity studies Eur. J. Pharm. Biopharm. 86 2014 244 250
    • (2014) Eur. J. Pharm. Biopharm. , vol.86 , pp. 244-250
    • Sahle, F.F.1    Wohlrab, J.2    Neubert, R.H.H.3
  • 134
    • 84904695244 scopus 로고    scopus 로고
    • Microemulsion based topical hydrogel of sertaconazole: Formulation, characterization and evaluation
    • S. Sahoo, N.R. Pani, and S.K. Sahoo Microemulsion based topical hydrogel of sertaconazole: formulation, characterization and evaluation Colloids Surf. B Biointerf. 120 2014 193 199
    • (2014) Colloids Surf. B Biointerf. , vol.120 , pp. 193-199
    • Sahoo, S.1    Pani, N.R.2    Sahoo, S.K.3
  • 135
    • 0344826779 scopus 로고    scopus 로고
    • Epidermal thickness at different body sites: Relationship to age, gender, pigmentation, blood content, skin type and smoking habits
    • J. Sandby-Møller, T. Poulsen, and H.C. Wulf Epidermal thickness at different body sites: relationship to age, gender, pigmentation, blood content, skin type and smoking habits Acta Derm. Venereol. 83 2003 410 413
    • (2003) Acta Derm. Venereol. , vol.83 , pp. 410-413
    • Sandby-Møller, J.1    Poulsen, T.2    Wulf, H.C.3
  • 137
    • 53949103329 scopus 로고    scopus 로고
    • Reconstructed Epidermis and Full-Thickness Skin for Absorption Testing: Influence of the Vehicles used on Steroid Permeation
    • Schäfer-Korting, M., Mahmoud, A., Lombardi Borgia, S., Brüggener, B., Kleuser, B., Schreiber, S., Mehnert, W., 2008. Reconstructed Epidermis and Full-Thickness Skin for Absorption Testing: Influence of the Vehicles used on Steroid Permeation. ATLA 36, pp. 441-452.
    • (2008) ATLA , vol.36 , pp. 441-452
    • Schäfer-Korting, M.1
  • 138
    • 0035857715 scopus 로고    scopus 로고
    • Comparison of human skin or epidermis models with human and animal skin in in-vitro percutaneous absorption
    • F.P. Schmook, J.G. Meingassner, and A. Billich Comparison of human skin or epidermis models with human and animal skin in in-vitro percutaneous absorption Int. J. Pharm. 215 2001 51 56
    • (2001) Int. J. Pharm. , vol.215 , pp. 51-56
    • Schmook, F.P.1    Meingassner, J.G.2    Billich, A.3
  • 142
    • 77349092809 scopus 로고    scopus 로고
    • Lecithin/chitosan nanoparticles of clobetasol-17-propionate capable of accumulation in pig skin
    • T. Senyigit, F. Sonvico, S. Barbieri, O. Ozer, P. Santi, and P. Colombo Lecithin/chitosan nanoparticles of clobetasol-17-propionate capable of accumulation in pig skin J. Control. Release 142 2010 368 373
    • (2010) J. Control. Release , vol.142 , pp. 368-373
    • Senyigit, T.1    Sonvico, F.2    Barbieri, S.3    Ozer, O.4    Santi, P.5    Colombo, P.6
  • 143
    • 77954178496 scopus 로고    scopus 로고
    • Studies on nonionic surfactant bilayer vesicles of ciclopirox olamine
    • K.S. Shaikh, B. Chellampillai, and A.P. Pawar Studies on nonionic surfactant bilayer vesicles of ciclopirox olamine Drug Dev. Ind. Pharm. 36 2010 946 953
    • (2010) Drug Dev. Ind. Pharm. , vol.36 , pp. 946-953
    • Shaikh, K.S.1    Chellampillai, B.2    Pawar, A.P.3
  • 145
    • 84913529186 scopus 로고    scopus 로고
    • D-optimal experimental approach for designing topical microemulsion of itraconazole: Characterization and evaluation of antifungal efficacy against a standardized Tinea pedis infection model in Wistar rats
    • N.K. Shishu D-optimal experimental approach for designing topical microemulsion of itraconazole: Characterization and evaluation of antifungal efficacy against a standardized Tinea pedis infection model in Wistar rats Eur. J. Pharm. Sci. 67 2015 97 112
    • (2015) Eur. J. Pharm. Sci. , vol.67 , pp. 97-112
    • Shishu, N.K.1
  • 146
    • 72449193597 scopus 로고    scopus 로고
    • A PAMPA study of the permeability-enhancing effect of new ceramide analogues
    • B. Sinko, J. Kokosi, A. Avdeef, and K. Takacs-Novak A PAMPA study of the permeability-enhancing effect of new ceramide analogues Chem. Biodivers. 6 2009 1867 1874
    • (2009) Chem. Biodivers. , vol.6 , pp. 1867-1874
    • Sinko, B.1    Kokosi, J.2    Avdeef, A.3    Takacs-Novak, K.4
  • 148
    • 33644626453 scopus 로고    scopus 로고
    • Transdermal drug delivery using microemulsion and aqueous systems: Influence of skin storage conditions on the in vitro permeability of diclofenac from aqueous vehicle systems
    • A.C. Sintov, and S. Botner Transdermal drug delivery using microemulsion and aqueous systems: influence of skin storage conditions on the in vitro permeability of diclofenac from aqueous vehicle systems Int. J. Pharm. 311 2006 55 62
    • (2006) Int. J. Pharm. , vol.311 , pp. 55-62
    • Sintov, A.C.1    Botner, S.2
  • 149
    • 84903378931 scopus 로고    scopus 로고
    • Comparative percutaneous permeation study using caffeine-loaded microemulsion showing low reliability of the frozen/thawed skin models
    • A.C. Sintov, and I. Greenberg Comparative percutaneous permeation study using caffeine-loaded microemulsion showing low reliability of the frozen/thawed skin models Int. J. Pharm. 471 2014 516 524
    • (2014) Int. J. Pharm. , vol.471 , pp. 516-524
    • Sintov, A.C.1    Greenberg, I.2
  • 151
    • 84859103475 scopus 로고    scopus 로고
    • Physico-chemical characteristics of methotrexate-entrapped oleic acid-containing deformable liposomes for in vitro transepidermal delivery targeting psoriasis treatment
    • P. Srisuk, P. Thongnopnua, U. Raktanonchai, and S. Kanokpanont Physico-chemical characteristics of methotrexate-entrapped oleic acid-containing deformable liposomes for in vitro transepidermal delivery targeting psoriasis treatment Int. J. Pharm. 427 2012 426 434
    • (2012) Int. J. Pharm. , vol.427 , pp. 426-434
    • Srisuk, P.1    Thongnopnua, P.2    Raktanonchai, U.3    Kanokpanont, S.4
  • 152
    • 83355164013 scopus 로고    scopus 로고
    • The effect of formulation vehicles on the in vitro percutaneous permeation of ibuprofen
    • J. Stahl, M. Wohlert, and M. Kietzmann The effect of formulation vehicles on the in vitro percutaneous permeation of ibuprofen BMC Pharmacol. 11 2011 12
    • (2011) BMC Pharmacol. , vol.11 , pp. 12
    • Stahl, J.1    Wohlert, M.2    Kietzmann, M.3
  • 153
    • 33749496372 scopus 로고    scopus 로고
    • Permeability and retention studies of (-)epicatechin gel formulations in human cadaver skin
    • J. Suppasrivasuseth, R.A. Bellantone, F.M. Plakogiannis, and G. Stagni Permeability and retention studies of (-)epicatechin gel formulations in human cadaver skin Drug Dev. Ind. Pharm. 32 2006 1007 1017
    • (2006) Drug Dev. Ind. Pharm. , vol.32 , pp. 1007-1017
    • Suppasrivasuseth, J.1    Bellantone, R.A.2    Plakogiannis, F.M.3    Stagni, G.4
  • 154
  • 155
    • 84978276451 scopus 로고    scopus 로고
    • A high throughput method to predict skin penetration and screen topical formulations
    • K. Tsinman, and B. Sinko A high throughput method to predict skin penetration and screen topical formulations Cosmet. Toiletries 128 2013 192 199
    • (2013) Cosmet. Toiletries , vol.128 , pp. 192-199
    • Tsinman, K.1    Sinko, B.2
  • 156
    • 0030984854 scopus 로고    scopus 로고
    • Keratin immobilized on silica as a new stationary phase for chromatographic modelling of skin permeation
    • M. Turowski, and R. Kaliszan Keratin immobilized on silica as a new stationary phase for chromatographic modelling of skin permeation J. Pharm. Biomed. Anal. 15 1997 1325 1333
    • (1997) J. Pharm. Biomed. Anal. , vol.15 , pp. 1325-1333
    • Turowski, M.1    Kaliszan, R.2
  • 157
    • 79956212332 scopus 로고    scopus 로고
    • Three-dimensional skin models as tools for transdermal drug delivery: Challenges and limitations
    • M. Van Gele, B. Geusens, L. Brochez, R. Speeckaert, and J. Lambert Three-dimensional skin models as tools for transdermal drug delivery: challenges and limitations Expert Opin. Drug Deliv. 8 2011 705 720
    • (2011) Expert Opin. Drug Deliv. , vol.8 , pp. 705-720
    • Van Gele, M.1    Geusens, B.2    Brochez, L.3    Speeckaert, R.4    Lambert, J.5
  • 159
    • 0035839177 scopus 로고    scopus 로고
    • Interrelation of permeation and penetration parameters obtained from in vitro experiments with human skin and skin equivalents
    • H. Wagner, K.-H. Kostka, C.-M. Lehr, and U.F. Schaefer Interrelation of permeation and penetration parameters obtained from in vitro experiments with human skin and skin equivalents J. Control. Release 75 2001 283 295
    • (2001) J. Control. Release , vol.75 , pp. 283-295
    • Wagner, H.1    Kostka, K.-H.2    Lehr, C.-M.3    Schaefer, U.F.4
  • 160
    • 58849145537 scopus 로고    scopus 로고
    • Predicting skin permeability using liposome electrokinetic chromatography
    • Y. Wang, J. Sun, H. Liu, J. Liu, L. Zhang, K. Liu, and Z. He Predicting skin permeability using liposome electrokinetic chromatography Analyst 134 2009 267 272
    • (2009) Analyst , vol.134 , pp. 267-272
    • Wang, Y.1    Sun, J.2    Liu, H.3    Liu, J.4    Zhang, L.5    Liu, K.6    He, Z.7
  • 161
    • 84907484238 scopus 로고    scopus 로고
    • Nanovesicular system containing tretinoin for dermal targeting delivery and rosacea treatment: A comparison of hexosomes, glycerosomes and ethosomes
    • J. Wang, F. Guo, M. Ma, M. Lei, F. Tan, and N. Li Nanovesicular system containing tretinoin for dermal targeting delivery and rosacea treatment: a comparison of hexosomes, glycerosomes and ethosomes RSC Adv. 4 2014 45458 45466
    • (2014) RSC Adv. , vol.4 , pp. 45458-45466
    • Wang, J.1    Guo, F.2    Ma, M.3    Lei, M.4    Tan, F.5    Li, N.6
  • 162
    • 84882790226 scopus 로고    scopus 로고
    • Modelling skin permeability with micellar liquid chromatography
    • L.J. Waters, Y. Shahzad, and J. Stephenson Modelling skin permeability with micellar liquid chromatography Eur. J. Pharm. Sci. 50 2013 335 340
    • (2013) Eur. J. Pharm. Sci. , vol.50 , pp. 335-340
    • Waters, L.J.1    Shahzad, Y.2    Stephenson, J.3
  • 163
    • 67749102207 scopus 로고    scopus 로고
    • Optimisation of cosolvent concentration for topical drug delivery II: Influence of propylene glycol on ibuprofen permeation
    • R.M. Watkinson, R.H. Guy, J. Hadgraft, and M.E. Lane Optimisation of cosolvent concentration for topical drug delivery II: influence of propylene glycol on ibuprofen permeation Skin Pharmacol. Physiol. 22 2009 225 230
    • (2009) Skin Pharmacol. Physiol. , vol.22 , pp. 225-230
    • Watkinson, R.M.1    Guy, R.H.2    Hadgraft, J.3    Lane, M.E.4
  • 164
    • 57649093872 scopus 로고    scopus 로고
    • Influence of ethanol on the solubility, ionization and permeation characteristics of ibuprofen in silicone and human skin
    • R.M. Watkinson, C. Herkenne, R.H. Guy, J. Hadgraft, G. Oliveira, and M.E. Lane Influence of ethanol on the solubility, ionization and permeation characteristics of ibuprofen in silicone and human skin Skin Pharmacol. Physiol. 22 2009 15 21
    • (2009) Skin Pharmacol. Physiol. , vol.22 , pp. 15-21
    • Watkinson, R.M.1    Herkenne, C.2    Guy, R.H.3    Hadgraft, J.4    Oliveira, G.5    Lane, M.E.6
  • 165
    • 77954307697 scopus 로고    scopus 로고
    • Optimisation of cosolvent concentration for topical drug delivery III - Influence of lipophilic vehicles on ibuprofen permeation
    • R.M. Watkinson, R.H. Guy, G. Oliveira, J. Hadgraft, and M.E. Lane Optimisation of cosolvent concentration for topical drug delivery III - influence of lipophilic vehicles on ibuprofen permeation Skin Pharmacol. Physiol. 24 2011 22 26
    • (2011) Skin Pharmacol. Physiol. , vol.24 , pp. 22-26
    • Watkinson, R.M.1    Guy, R.H.2    Oliveira, G.3    Hadgraft, J.4    Lane, M.E.5
  • 166
    • 0035222638 scopus 로고    scopus 로고
    • Reconstructed skin equivalents for assessing percutaneous drug absorption from pharmaceutical formulations
    • N. Zghoul, R. Fuchs, C.-M. Lehr, and U.F. Schaefer Reconstructed skin equivalents for assessing percutaneous drug absorption from pharmaceutical formulations ALTEX 18 2001 103 106
    • (2001) ALTEX , vol.18 , pp. 103-106
    • Zghoul, N.1    Fuchs, R.2    Lehr, C.-M.3    Schaefer, U.F.4
  • 167
    • 67449155891 scopus 로고    scopus 로고
    • A dynamic topical hydrofluoroalkane foam to induce nanoparticle modification and drug release in situ
    • Y. Zhao, M. Moddaresi, S.A. Jones, and M.B. Brown A dynamic topical hydrofluoroalkane foam to induce nanoparticle modification and drug release in situ Eur. J. Pharm. Biopharm. 72 2009 521 528
    • (2009) Eur. J. Pharm. Biopharm. , vol.72 , pp. 521-528
    • Zhao, Y.1    Moddaresi, M.2    Jones, S.A.3    Brown, M.B.4
  • 169
    • 84897851538 scopus 로고    scopus 로고
    • Storage stability and skin permeation of vitamin C liposomes improved by pectin coating
    • W. Zhou, W. Liu, L. Zou, C. Liu, C. Liu, R. Liang, and J. Chen Storage stability and skin permeation of vitamin C liposomes improved by pectin coating Colloids Surf. B Biointerf. 117 2014 330 337
    • (2014) Colloids Surf. B Biointerf. , vol.117 , pp. 330-337
    • Zhou, W.1    Liu, W.2    Zou, L.3    Liu, C.4    Liu, C.5    Liang, R.6    Chen, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.