The role of vehicle interactions on permeation of an active through model membranes and human skin

International Journal of Cosmetic Science

Volumn 34, Issue 6, 2012, Pages 536-545

  Oliveira, G ^a   Hadgraft, J ^a   Lane, Majella E ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

human skin; methyl paraben; partition; permeation; silicone membrane; uptake; vehicle enhancement model

Indexed keywords

ALCOHOL; DIETHYLENE GLYCOL MONOETHYL ETHER; DIMETHYL ISOSORBIDE; DRUG VEHICLE; MACROGOL; MACROGOL 400; METHYL PARABEN; MYRISTIC ACID ISOPROPYL ESTER; SILICONE; UNCLASSIFIED DRUG;

ARTICLE; ARTIFICIAL MEMBRANE; CRYSTALLIZATION; DIFFUSION; DIFFUSION COEFFICIENT; HUMAN; HUMAN TISSUE; MEMBRANE TRANSPORT; STRATUM CORNEUM;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; MEMBRANES, ARTIFICIAL; PARABENS; PHARMACEUTICAL VEHICLES; SILICONES; SKIN ABSORPTION;

EID: 84868211539     PISSN: 01425463     EISSN: 14682494     Source Type: Journal    
DOI: 10.1111/j.1468-2494.2012.00753.x     Document Type: Article

References (35)

1. Dias, M., Hadgraft, J., and, Lane, M.E., Influence of membrane-solvent-solute interactions on solute permeation in skin. Int. J. Pharm. 340, 65-70 (2007).
2. Rosado, C., Cross, S.E., Pugh, W.J., Roberts, M.S., and, Hadgraft, J., Effect of vehicle pretreatment on the flux, retention, and diffusion of topically applied penetrants in vitro. Pharm. Res. 20, 1502-1507 (2003).
3. Alberti, I., Kalia, Y.N., Naik, A., Bonny, J.-D., and, Guy, R.H., Effect of ethanol and isopropyl myristate on the availability of topical terbinafine in human stratum corneum, in vivo. Int. J. Pharm. 219, 11-19 (2001).
4. Watkinson, R.M., Guy, R.H., Hadgraft, J., and, Lane, M.E., Optimisation of cosolvent concentration for topical drug delivery II: influence of propylene glycol on ibuprofen permeation. Skin Pharmacol. Physiol. 22, 225-230 (2009).
5. Zhang, Q., Li, P., and, Roberts, M.S., Maximum transepidermal flux for similar size phenolic compounds is enhanced by solvent uptake into the skin. J. Controlled Release 154, 50-57 (2011).
6. Franz, T.J., Percutaneous absorption. On the relevance of in vitro data. J. Invest. Dermatol. 64, 190-195 (1975).
7. Higuchi, T., Physical chemical analysis of percutaneous absorption process from creams and ointments. J. Soc. Cosmet. Chem. 11, 85-97 (1960).
8. Crank, J., The Mathematics of Diffusion, 2nd edn. Clarendon Press, Oxford (1975).
9. McAuley, W.J., Oliveira, G., Mohammed, D., Beezer, A.E., Hadgraft, J., and, Lane, M.E., Thermodynamic considerations of solvent/enhancer uptake into a model membrane. Int. J. Pharm. 396, 134-139 (2010).
10. Oliveira, G., Beezer, A.E., Hadgraft, J., and, Lane, M.E., Alcohol enhanced permeation in model membranes. Part I. Thermodynamic and kinetic analyses of membrane permeation. Int. J. Pharm. 393, 61-67 (2010).
11. Oliveira, G., Beezer, A.E., Hadgraft, J., and, Lane, M.E., Alcohol enhanced permeation in model membranes. Part II. Thermodynamic analysis of membrane partitioning. Int. J. Pharm. 420, 216-222 (2011).
12. Kai, T., Mak, V.H.W., Potts, R.O., and, Guy, R.H., Mechanism of percutaneous penetration enhancement: effect of n-alkanols on the permeability barrier of hairless mouse skin. J. Controlled Release 12, 103-112 (1990).
13. Dias, M., Naik, A., Guy, R.H., Hadgraft, J., and, Lane, M.E., In vivo infrared spectroscopy studies of alkanol effects on human skin. Eur. J. Pharm. Biopharm. 69, 1171-1175 (2008).
14. Oliveira, G., Hadgraft, J., and, Lane, M.E., The influence of volatile solvents on transport across model membranes and human skin. Int. J. Pharm. 435, 38-49 (2012).
15. Kligman, A.M., and, Christophers, E., Preparation of Isolated Sheets of Human Stratum Corneum. Arch. Dermatol. 88, 702-705 (1963).
16. Silva, C.L., Nunes, S.C.C., Eusébio, M.E.S., Pais, A.A.C.C., and, Sousa, J.J.S., Thermal Behaviour of Human Stratum Corneum. Skin Pharmacol. Physiol. 19, 132-139 (2006).
17. Wexler, A., Constant Humidity Solutions (Section 15-Practical Laboratory data), 87th edn. CRC Press, Boca Raton (2008).
18. Alexander, K.S., Mauger, J.W., Petersen, H., and, Paruta, A.N., Solubility profiles and thermodynamics of parabens in aliphatic alcohols. J. Pharm. Sci. 66, 42-48 (1977).
19. Shihab, F., Sheffield, W., Sprowls, J., and, Nematollahi, J., Solubility of alkyl benzoates I: effect of some alkyl p-hydroxybenzoates (parabens) on the solubility of benzyl p-hydroxybenzoate. J. Pharm. Sci. 59, 1574-1577 (1970).
20. Cross, S.E., Pugh, W.J., Hadgraft, J., and, Roberts, M.S., Probing the effect of vehicles on topical delivery: understanding the basic relationship between solvent and solute penetration using silicone membranes. Pharm. Res. 18, 999-1005 (2001).
21. Dias, M., Hadgraft, J., and, Lane, M.E., Influence of membrane-solvent-solute interactions on solute permeation in model membranes. Int. J. Pharm. 336, 108-114 (2007).
22. Liu, P., Cettina, M., and, Wong, J., Effects of isopropanol-isopropyl myristate binary enhancers on in vitro transport of estradiol in human epidermis: a mechanistic evaluation. J. Pharm. Sci. 98, 565-572 (2009).
23. Shah, J.C., Analysis of permeation data: evaluation of the lag time method. Int. J. Pharm. 90, 161-169 (1993).
24. Dias, M., Raghavan, S.L., and, Hadgraft, J., ATR-FTIR spectroscopic investigations on the effect of solvents on the permeation of benzoic acid and salicylic acid through silicone membranes. Int. J. Pharm. 216, 51-59 (2001).
25. Dias, M., Hadgraft, J., Raghavan, S.L., and, Tetteh, J., The effect of solvent on permeant diffusion through membranes studied using ATR-FTIR and chemometric data analysis. J. Pharm. Sci. 93, 186-196 (2004).
26. Twist, J.N., and, Zatz, J.L., Membrane-solvent-solute interaction in a model permeation system. J. Pharm. Sci. 77, 536-540 (1988).
27. Twist, J.N., and, Zatz, J.L., A model for alcohol-enhanced permeation through polydimethylsiloxane membranes. J. Pharm. Sci. 79, 28-31 (1990).
28. Twist, J.N., and, Zatz, J.L., Influence of solvents on paraben permeation through idealized skin model membranes. J. Soc. Cosmet. Chem. 37, 429-444 (1986).
29. Michaels, A.S., Chandrasekaran, S.K., and, Shaw, J.E., Drug permeation through human skin: theory and in vitro experimental measurement. AIChE J. 21, 985-996 (1975).
30. Guillard, E.C., Laugel, C., and, Baillet-Guffroy, A., Molecular interactions of penetration enhancers within ceramides organization: A FTIR approach. Eur. J. Pharm. Sci. 36, 192-199 (2009).
31. Liron, Z., and, Cohen, S., Percutaneous absorption of alkanoic acids II: application of regular solution theory. J. Pharm. Sci. 73, 538-542 (1984).
32. Most, C.F., Co-permeant enhancement of drug transmission rates through silicone rubber. J. Biomed. Mater. Res. 6, 3-14 (1972).
33. Potts, R.O., and, Guy, R.H., Predicting skin permeability. Pharm. Res. 9, 663-669 (1992).
34. Ongpipattanakul, B., Burnette, R., Potts, R., and, Francoeur, M., Evidence that oleic acid exists in a separate phase within Stratum Corneum lipids. Pharm. Res. 8, 350-354 (1991).
35. Santos, P., Watkinson, A.C., Hadgraft, J., and, Lane, M.E., Formulation issues associated with transdermal fentanyl delivery. Int. J. Pharm. 416, 155-159 (2011).