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Volumn 23, Issue 1, 2009, Pages 1-13

Pig and guinea pig skin as surrogates for human in vitro penetration studies: A quantitative review

Author keywords

Animal model; Dermal penetration; Guinea pig; Human; In vitro model; Lag time; Permeability; Pig; Skin absorption

Indexed keywords

CORRELATION COEFFICIENT; DOMESTIC PIG; GUINEA PIG; HUMAN; IN VITRO STUDY; INTRASPECIFIC VARIATION; NONHUMAN; ORGAN PRESERVATION; QUANTITATIVE ANALYSIS; REVIEW; SKIN ABSORPTION; SKIN PENETRATION; SKIN PERMEABILITY; SKIN STRUCTURE; SWINE;

EID: 58149191280     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2008.10.008     Document Type: Review
Times cited : (288)

References (118)
  • 1
    • 0036812998 scopus 로고    scopus 로고
    • Transdermal delivery of nicardipine: an approach to in vitro permeation enhancement
    • Aboofazeli R., Zia H., and Needham T.E. Transdermal delivery of nicardipine: an approach to in vitro permeation enhancement. Drug Delivery 9 (2002) 239-247
    • (2002) Drug Delivery , vol.9 , pp. 239-247
    • Aboofazeli, R.1    Zia, H.2    Needham, T.E.3
  • 3
    • 34247495915 scopus 로고    scopus 로고
    • Variability in human skin permeability in vitro: comparing penetrants with different physicochemical properties
    • Akomeah F.K., Martin G.P., and Brown M.B. Variability in human skin permeability in vitro: comparing penetrants with different physicochemical properties. Journal of Pharmaceutical sciences 96 (2007) 824-834
    • (2007) Journal of Pharmaceutical sciences , vol.96 , pp. 824-834
    • Akomeah, F.K.1    Martin, G.P.2    Brown, M.B.3
  • 4
    • 36348930977 scopus 로고    scopus 로고
    • Qualitative and quantitative comparison of heat separated epidermis and dermatomed skin in percutaneous absorption studies
    • Atrux-Tallau N., Pirot F., Falson F., Roberts M.S., and Maibach H.I. Qualitative and quantitative comparison of heat separated epidermis and dermatomed skin in percutaneous absorption studies. Archives of Dermatological Research 299 (2007) 507-511
    • (2007) Archives of Dermatological Research , vol.299 , pp. 507-511
    • Atrux-Tallau, N.1    Pirot, F.2    Falson, F.3    Roberts, M.S.4    Maibach, H.I.5
  • 5
    • 0025228052 scopus 로고
    • Transdermal oxymorphone formulation development and methods for evaluating flux and lag times for two skin permeation-enhancing vehicles
    • Aungst B.J., Blake J.A., Rogers N.J., and Hussain M.A. Transdermal oxymorphone formulation development and methods for evaluating flux and lag times for two skin permeation-enhancing vehicles. Journal of Pharmaceutical Sciences 79 (1990) 1072-1076
    • (1990) Journal of Pharmaceutical Sciences , vol.79 , pp. 1072-1076
    • Aungst, B.J.1    Blake, J.A.2    Rogers, N.J.3    Hussain, M.A.4
  • 6
    • 44649083690 scopus 로고    scopus 로고
    • Flux across of microneedle-treated skin is increased by increasing charge of naltrexone and naltrexol in vitro
    • Banks S.L., Pinninti R., Gill H., Crooks P., Prausnitz M., and Stinchcomb A. Flux across of microneedle-treated skin is increased by increasing charge of naltrexone and naltrexol in vitro. Pharmaceutical Research 25 (2008) 1677-1685
    • (2008) Pharmaceutical Research , vol.25 , pp. 1677-1685
    • Banks, S.L.1    Pinninti, R.2    Gill, H.3    Crooks, P.4    Prausnitz, M.5    Stinchcomb, A.6
  • 7
    • 0345560875 scopus 로고
    • Choice of membranes for in vitro skin uptake studies and general experimental techniques
    • Kemppainen B.W., and Reifenrath W.G. (Eds), CRC, Boca Raton
    • Behl C.R., Kumar S., Malick A.W., Patel H., Char H., and Piemontese D. Choice of membranes for in vitro skin uptake studies and general experimental techniques. In: Kemppainen B.W., and Reifenrath W.G. (Eds). Methods for Skin Absorption (1990), CRC, Boca Raton 1-21
    • (1990) Methods for Skin Absorption , pp. 1-21
    • Behl, C.R.1    Kumar, S.2    Malick, A.W.3    Patel, H.4    Char, H.5    Piemontese, D.6
  • 9
    • 0028102432 scopus 로고
    • Characterization of esterase and alcohol dehydrogenase activity in skin. Metabolism of retinyl palmitate to retinol (vitamin A) during percutaneous absorption
    • Boehnlein J., Sakr A., Lichtin J.L., and Bronaugh R.L. Characterization of esterase and alcohol dehydrogenase activity in skin. Metabolism of retinyl palmitate to retinol (vitamin A) during percutaneous absorption. Pharmaceutical Research 11 (1994) 1155-1159
    • (1994) Pharmaceutical Research , vol.11 , pp. 1155-1159
    • Boehnlein, J.1    Sakr, A.2    Lichtin, J.L.3    Bronaugh, R.L.4
  • 10
    • 47549100363 scopus 로고    scopus 로고
    • Percutaneous penetration and absorption of parathion using human and pig skin models in vitro and human skin grafted onto nude mouse skin model in vivo
    • Boudry I., Blanck O., Cruz C., Blanck M., Vallet V., Bazire A., Capt A., Josse D., and Lallement G. Percutaneous penetration and absorption of parathion using human and pig skin models in vitro and human skin grafted onto nude mouse skin model in vivo. Journal of Applied Toxicology 28 (2008) 645-657
    • (2008) Journal of Applied Toxicology , vol.28 , pp. 645-657
    • Boudry, I.1    Blanck, O.2    Cruz, C.3    Blanck, M.4    Vallet, V.5    Bazire, A.6    Capt, A.7    Josse, D.8    Lallement, G.9
  • 13
    • 8544262290 scopus 로고
    • Determination of percutanous absorption by in vitro techniques
    • Bronaugh R., and Maibach H. (Eds), Marcel Dekker Inc., New York
    • Bronaugh R. Determination of percutanous absorption by in vitro techniques. In: Bronaugh R., and Maibach H. (Eds). Percutaneous Absorption: Mechanism, Methodology, and Drug Delivery (1985), Marcel Dekker Inc., New York 267-279
    • (1985) Percutaneous Absorption: Mechanism, Methodology, and Drug Delivery , pp. 267-279
    • Bronaugh, R.1
  • 14
    • 0009545964 scopus 로고
    • Preparation of biological membranes
    • Kemppainen B.W., and Reifenrath W.G. (Eds), CRC, Boca Raton
    • Bronaugh R. Preparation of biological membranes. In: Kemppainen B.W., and Reifenrath W.G. (Eds). Methods for Skin Absorption (1990), CRC, Boca Raton 61-66
    • (1990) Methods for Skin Absorption , pp. 61-66
    • Bronaugh, R.1
  • 16
    • 0020067173 scopus 로고
    • Methods for in vitro percutaneous absorption studies. II. Animal models for human skin
    • Bronaugh R.L., Stewart R.F., and Congdon E.R. Methods for in vitro percutaneous absorption studies. II. Animal models for human skin. Toxicology and Applied Pharmacology 62 (1982) 481-488
    • (1982) Toxicology and Applied Pharmacology , vol.62 , pp. 481-488
    • Bronaugh, R.L.1    Stewart, R.F.2    Congdon, E.R.3
  • 17
    • 0022976340 scopus 로고
    • Methods for in vitro percutaneous absorption studies. VII: use of excised human skin
    • Bronaugh R.L., Stewart R.F., and Simon M. Methods for in vitro percutaneous absorption studies. VII: use of excised human skin. Journal of Pharmaceutical Sciences 75 (1986) 1094-1097
    • (1986) Journal of Pharmaceutical Sciences , vol.75 , pp. 1094-1097
    • Bronaugh, R.L.1    Stewart, R.F.2    Simon, M.3
  • 18
    • 0021729764 scopus 로고
    • Gastrointestinal and dermal absorption: interspecies differences
    • Calabrese E.J. Gastrointestinal and dermal absorption: interspecies differences. Drug Metabolism Reviews 15 (1984) 1013-1032
    • (1984) Drug Metabolism Reviews , vol.15 , pp. 1013-1032
    • Calabrese, E.J.1
  • 19
    • 0025162194 scopus 로고
    • Transdermal delivery of levonorgestrel. VIII. Effect of enhancers on rat skin, hairless mouse skin, hairless guinea pig skin, and human skin
    • Catz P., and Friend D.R. Transdermal delivery of levonorgestrel. VIII. Effect of enhancers on rat skin, hairless mouse skin, hairless guinea pig skin, and human skin. International Journal of Pharmaceutics 58 (1990) 93-102
    • (1990) International Journal of Pharmaceutics , vol.58 , pp. 93-102
    • Catz, P.1    Friend, D.R.2
  • 20
    • 0034885107 scopus 로고    scopus 로고
    • In vitro skin absorption and decontamination of sulphur mustard: comparison of human and pig ear skin
    • Chilcott R.P., Jenner J., Hotchkiss S.A.M., and Rice P. In vitro skin absorption and decontamination of sulphur mustard: comparison of human and pig ear skin. Journal of Applied Toxicology 21 (2001) 279-283
    • (2001) Journal of Applied Toxicology , vol.21 , pp. 279-283
    • Chilcott, R.P.1    Jenner, J.2    Hotchkiss, S.A.M.3    Rice, P.4
  • 22
    • 33749861610 scopus 로고    scopus 로고
    • Absorption of the nerve agent VX (O-ethyl-S-[2(di-isopropylamino)ethyl] methyl phosphonothioate) through pig, human and guinea pig skin in vitro
    • Dalton C.H., Hattersley I.J., Rutter S.J., and Chilcott R.P. Absorption of the nerve agent VX (O-ethyl-S-[2(di-isopropylamino)ethyl] methyl phosphonothioate) through pig, human and guinea pig skin in vitro. Toxicology in Vitro 20 (2006) 1532-1536
    • (2006) Toxicology in Vitro , vol.20 , pp. 1532-1536
    • Dalton, C.H.1    Hattersley, I.J.2    Rutter, S.J.3    Chilcott, R.P.4
  • 23
    • 1642378629 scopus 로고    scopus 로고
    • Multi-species assessment of electrical resistance as a skin integrity marker for in vitro percutaneous absorption studies
    • Davies D.J., Ward R.J., and Heylings J.R. Multi-species assessment of electrical resistance as a skin integrity marker for in vitro percutaneous absorption studies. Toxicology in Vitro 18 (2004) 351-358
    • (2004) Toxicology in Vitro , vol.18 , pp. 351-358
    • Davies, D.J.1    Ward, R.J.2    Heylings, J.R.3
  • 24
    • 0024395179 scopus 로고
    • Determination of octanol/water partition coefficients for hydrophobic organic chemicals with the slow-stirring method
    • De Bruijn J., Busser F., Seinen W., and Hermens J. Determination of octanol/water partition coefficients for hydrophobic organic chemicals with the slow-stirring method. Environmental Toxicology and Chemistry 8 (1989) 499-512
    • (1989) Environmental Toxicology and Chemistry , vol.8 , pp. 499-512
    • De Bruijn, J.1    Busser, F.2    Seinen, W.3    Hermens, J.4
  • 25
    • 0026706844 scopus 로고
    • Pig ear skin as an in-vitro model for human skin permeability
    • Dick I.P., and Scott R.C. Pig ear skin as an in-vitro model for human skin permeability. Journal of Pharmacy and Pharmacology 44 (1992) 640-645
    • (1992) Journal of Pharmacy and Pharmacology , vol.44 , pp. 640-645
    • Dick, I.P.1    Scott, R.C.2
  • 27
    • 0025821769 scopus 로고
    • Epidermal barrier function: intercellular lamellar lipid structures, origen, composition and metabolism
    • Elias P.M. Epidermal barrier function: intercellular lamellar lipid structures, origen, composition and metabolism. Journal of Controlled Release 15 (1991) 199-208
    • (1991) Journal of Controlled Release , vol.15 , pp. 199-208
    • Elias, P.M.1
  • 28
    • 0019820246 scopus 로고
    • Percutaneous transport in relation to stratum corneum structure and lipid composition
    • Elias P.M., Cooper E.R., Korc A., and Brown B.E. Percutaneous transport in relation to stratum corneum structure and lipid composition. Journal of Investigative Dermatology 76 (1981) 297-301
    • (1981) Journal of Investigative Dermatology , vol.76 , pp. 297-301
    • Elias, P.M.1    Cooper, E.R.2    Korc, A.3    Brown, B.E.4
  • 29
    • 0036848940 scopus 로고    scopus 로고
    • Human skin sandwich for assessing shunt route penetration during passive and iontophoretic drug and liposome delivery
    • Essa E.A., Bonner M.C., and Barry B.W. Human skin sandwich for assessing shunt route penetration during passive and iontophoretic drug and liposome delivery. Journal of Pharmacy and Pharmacology 54 (2002) 1481-1490
    • (2002) Journal of Pharmacy and Pharmacology , vol.54 , pp. 1481-1490
    • Essa, E.A.1    Bonner, M.C.2    Barry, B.W.3
  • 31
    • 0029562672 scopus 로고
    • In vitro permeation study of capsaicin and its synthetic derivatives from ointment bases using various skin types
    • Fang J.Y., Wu P.C., Huang Y.B., and Tsai Y.H. In vitro permeation study of capsaicin and its synthetic derivatives from ointment bases using various skin types. International Journal of Pharmaceutics 126 (1995) 119-128
    • (1995) International Journal of Pharmaceutics , vol.126 , pp. 119-128
    • Fang, J.Y.1    Wu, P.C.2    Huang, Y.B.3    Tsai, Y.H.4
  • 33
    • 34347402217 scopus 로고    scopus 로고
    • Skin penetration and lag times of neat and aqueous diethyl phthalate, 1,2-dichloroethane and naphthalene
    • Frasch H.F., Barbero A.M., Alachkar H., and McDougal J.N. Skin penetration and lag times of neat and aqueous diethyl phthalate, 1,2-dichloroethane and naphthalene. Cutaneous and Ocular Toxicology 26 (2007) 147-160
    • (2007) Cutaneous and Ocular Toxicology , vol.26 , pp. 147-160
    • Frasch, H.F.1    Barbero, A.M.2    Alachkar, H.3    McDougal, J.N.4
  • 34
    • 0017033158 scopus 로고
    • The in vitro permeability of skin and buccal mucosa to selected drugs and tritiated water
    • Galey W.R., Lonsdale H.K., and Nacht S. The in vitro permeability of skin and buccal mucosa to selected drugs and tritiated water. Journal of Investigative Dermatology 67 (1976) 713-717
    • (1976) Journal of Investigative Dermatology , vol.67 , pp. 713-717
    • Galey, W.R.1    Lonsdale, H.K.2    Nacht, S.3
  • 35
    • 35349002202 scopus 로고    scopus 로고
    • Transdermal skin delivery: predictions for humans from in vivo, ex vivo and animal models
    • Godin B., and Touitou E. Transdermal skin delivery: predictions for humans from in vivo, ex vivo and animal models. Advanced Drug Delivery Reviews 59 (2007) 1152-1161
    • (2007) Advanced Drug Delivery Reviews , vol.59 , pp. 1152-1161
    • Godin, B.1    Touitou, E.2
  • 36
    • 0031901774 scopus 로고    scopus 로고
    • Comparative biomembrane permeation of tacrine using Yucatan minipigs and domestic pigs as the animal model
    • Gore A.V., Liang A.C., and Chien Y.W. Comparative biomembrane permeation of tacrine using Yucatan minipigs and domestic pigs as the animal model. Journal of Pharmaceutical Sciences 87 (1998) 441-447
    • (1998) Journal of Pharmaceutical Sciences , vol.87 , pp. 441-447
    • Gore, A.V.1    Liang, A.C.2    Chien, Y.W.3
  • 37
    • 0018191471 scopus 로고
    • Glycosphingolipids and ceramides in human and pig epidermis
    • Gray G.M., and White R.J. Glycosphingolipids and ceramides in human and pig epidermis. Journal of Investigative Dermatology 70 (1978) 336-341
    • (1978) Journal of Investigative Dermatology , vol.70 , pp. 336-341
    • Gray, G.M.1    White, R.J.2
  • 39
    • 0022622856 scopus 로고
    • Influence of skin source, penetration cell fluid, and partition coefficient on in vitro skin penetration
    • Hawkins G.S., and Reifenrath W.G. Influence of skin source, penetration cell fluid, and partition coefficient on in vitro skin penetration. Journal of Pharmaceutical Sciences 75 (1986) 378-811
    • (1986) Journal of Pharmaceutical Sciences , vol.75 , pp. 378-811
    • Hawkins, G.S.1    Reifenrath, W.G.2
  • 40
    • 37349074682 scopus 로고    scopus 로고
    • Probing the permeation enhancement of mefenamic acid by ethanol across full-thickness skin, heat-separated epidermal membrane and heat-separated dermal membrane
    • Heard C.M., and Screen C. Probing the permeation enhancement of mefenamic acid by ethanol across full-thickness skin, heat-separated epidermal membrane and heat-separated dermal membrane. International Journal of Pharmaceutics 349 (2008) 323-325
    • (2008) International Journal of Pharmaceutics , vol.349 , pp. 323-325
    • Heard, C.M.1    Screen, C.2
  • 41
    • 41149143036 scopus 로고    scopus 로고
    • Influence of human skin specimens consisting of different skin layers on the result of in vitro permeation experiments
    • Henning A., Neumann D., Kostka K.H., Lehr C.M., and Schaefer U.F. Influence of human skin specimens consisting of different skin layers on the result of in vitro permeation experiments. Skin Pharmacology and Physiology 21 (2008) 81-88
    • (2008) Skin Pharmacology and Physiology , vol.21 , pp. 81-88
    • Henning, A.1    Neumann, D.2    Kostka, K.H.3    Lehr, C.M.4    Schaefer, U.F.5
  • 42
    • 0016252415 scopus 로고    scopus 로고
    • Regional differences in the thickness (cell layers) of the human stratum corneum: an ultrastructural analysis
    • Holbrook K.A., and Odland G.F. Regional differences in the thickness (cell layers) of the human stratum corneum: an ultrastructural analysis. Journal of Investigative Dermatology 62 (2001) 415-422
    • (2001) Journal of Investigative Dermatology , vol.62 , pp. 415-422
    • Holbrook, K.A.1    Odland, G.F.2
  • 43
    • 0030008490 scopus 로고    scopus 로고
    • In vitro percutaneous absorption of the fragrance ingredient musk xylol
    • Hood H.L., Wickett R.R., and Bronaugh R.L. In vitro percutaneous absorption of the fragrance ingredient musk xylol. Food and Chemical Toxicology 34 (1996) 483-488
    • (1996) Food and Chemical Toxicology , vol.34 , pp. 483-488
    • Hood, H.L.1    Wickett, R.R.2    Bronaugh, R.L.3
  • 44
    • 2942637821 scopus 로고    scopus 로고
    • Human systemic exposure to a [14C]-para-phenylenediamine-containing oxidative hair dye and correlation with in vitro percutaneous absorption in human or pig skin
    • Hueber-Becker F., Nohynek G.J., Meuling W.J., ech-Kieffer F., and Toutain H. Human systemic exposure to a [14C]-para-phenylenediamine-containing oxidative hair dye and correlation with in vitro percutaneous absorption in human or pig skin. Food and Chemical Toxicology 42 8 (2004) 1227-1236
    • (2004) Food and Chemical Toxicology , vol.42 , Issue.8 , pp. 1227-1236
    • Hueber-Becker, F.1    Nohynek, G.J.2    Meuling, W.J.3    ech-Kieffer, F.4    Toutain, H.5
  • 45
    • 0029923287 scopus 로고    scopus 로고
    • Transdermal controlled administration of verapamil - enhancement of skin permeability
    • Jain G.K., Sharma A.K., and Agrawal S.S. Transdermal controlled administration of verapamil - enhancement of skin permeability. International Journal of Pharmaceutics 130 (1996) 169-177
    • (1996) International Journal of Pharmaceutics , vol.130 , pp. 169-177
    • Jain, G.K.1    Sharma, A.K.2    Agrawal, S.S.3
  • 46
    • 0033832843 scopus 로고    scopus 로고
    • Percutaneous absorption and metabolism of dinitrochlorobenzene in vitro
    • Jewell C., Heylings J., Clowes H.M., and Williams F.M. Percutaneous absorption and metabolism of dinitrochlorobenzene in vitro. Archives of Toxicology 74 (2000) 356-365
    • (2000) Archives of Toxicology , vol.74 , pp. 356-365
    • Jewell, C.1    Heylings, J.2    Clowes, H.M.3    Williams, F.M.4
  • 47
  • 48
    • 0035848413 scopus 로고    scopus 로고
    • In vitro transdermal iontophoretic transport of timolol maleate: effect of age and species
    • Kanikkannan N., Singh J., and Ramarao P. In vitro transdermal iontophoretic transport of timolol maleate: effect of age and species. Journal of Controlled Release 71 (2001) 99-105
    • (2001) Journal of Controlled Release , vol.71 , pp. 99-105
    • Kanikkannan, N.1    Singh, J.2    Ramarao, P.3
  • 49
    • 0031754064 scopus 로고    scopus 로고
    • Percutaneous absorption of trinitrobenzene: animal models for human skin
    • Kraeling M.E., Reddy G., and Bronaugh R.L. Percutaneous absorption of trinitrobenzene: animal models for human skin. Journal of Applied Toxicology 18 (1998) 387-922
    • (1998) Journal of Applied Toxicology , vol.18 , pp. 387-922
    • Kraeling, M.E.1    Reddy, G.2    Bronaugh, R.L.3
  • 52
    • 0022448140 scopus 로고
    • Epidermal permeability barrier: transformation of lamellar granule-disks into intercellular sheets by a membrane-fusion process, a freeze-fracture study
    • Landmann L. Epidermal permeability barrier: transformation of lamellar granule-disks into intercellular sheets by a membrane-fusion process, a freeze-fracture study. Journal of Investigative Dermatology 87 (1986) 202-299
    • (1986) Journal of Investigative Dermatology , vol.87 , pp. 202-299
    • Landmann, L.1
  • 53
    • 0029421236 scopus 로고
    • Regional variation in content, composition and organization of porcine epithelial barrier lipids revealed by thin-layer chromatography and transmission electron microscopy
    • Law S., Wertz P.W., Swartzendruber D.C., and Squier C.A. Regional variation in content, composition and organization of porcine epithelial barrier lipids revealed by thin-layer chromatography and transmission electron microscopy. Archives of Oral Biology 40 (1995) 1085-1091
    • (1995) Archives of Oral Biology , vol.40 , pp. 1085-1091
    • Law, S.1    Wertz, P.W.2    Swartzendruber, D.C.3    Squier, C.A.4
  • 57
    • 0030670750 scopus 로고    scopus 로고
    • Skin absorption of the industrial catalyst dimethylethylamine in vitro in guinea pig and human skin, and of gaseous dimethylethylamine in human volunteers
    • Lundh T., Boman A., and Akesson B. Skin absorption of the industrial catalyst dimethylethylamine in vitro in guinea pig and human skin, and of gaseous dimethylethylamine in human volunteers. International Archives of Occupational and Environmental Health 70 (1997) 309-313
    • (1997) International Archives of Occupational and Environmental Health , vol.70 , pp. 309-313
    • Lundh, T.1    Boman, A.2    Akesson, B.3
  • 59
    • 0018228183 scopus 로고
    • The skin of domestic mammals as a model for the human skin, with special reference to the domestic pig
    • Meyer W., Schwarz R., and Neurand K. The skin of domestic mammals as a model for the human skin, with special reference to the domestic pig. Current Problems in Dermatology 7 (1978) 39-52
    • (1978) Current Problems in Dermatology , vol.7 , pp. 39-52
    • Meyer, W.1    Schwarz, R.2    Neurand, K.3
  • 60
    • 0042859035 scopus 로고    scopus 로고
    • The skin barrier
    • Freinkel R.K., and Woodley D.T. (Eds), Parthenon Publishing, New York
    • Micali G., Lacarrubba F., Bongu A., and West D.P. The skin barrier. In: Freinkel R.K., and Woodley D.T. (Eds). The Biology of the Skin (2000), Parthenon Publishing, New York 219-231
    • (2000) The Biology of the Skin , pp. 219-231
    • Micali, G.1    Lacarrubba, F.2    Bongu, A.3    West, D.P.4
  • 61
    • 0028304520 scopus 로고
    • Effects of absorption enhancers and lipid-composition on drug permeability through the model membrane using stratum-corneum lipids
    • Miyajima K., Tanikawa S., Asano M., and Matsuzaki K. Effects of absorption enhancers and lipid-composition on drug permeability through the model membrane using stratum-corneum lipids. Chemical and Pharmaceutical Bulletin 42 (1994) 1345-1347
    • (1994) Chemical and Pharmaceutical Bulletin , vol.42 , pp. 1345-1347
    • Miyajima, K.1    Tanikawa, S.2    Asano, M.3    Matsuzaki, K.4
  • 62
    • 0000883827 scopus 로고    scopus 로고
    • The pig as a model for cutaneous pharmacology and toxicology research
    • Tumbleson M.E., and Shook L.B. (Eds), Plenum Press, New York
    • Monteiro-Riviere N., and Riviere J.E. The pig as a model for cutaneous pharmacology and toxicology research. In: Tumbleson M.E., and Shook L.B. (Eds). Advances in Swine in Biomedical Research (1996), Plenum Press, New York 425-458
    • (1996) Advances in Swine in Biomedical Research , pp. 425-458
    • Monteiro-Riviere, N.1    Riviere, J.E.2
  • 63
    • 0034006931 scopus 로고    scopus 로고
    • Comparative in vitro percutaneous absorption of nonylphenol and nonylphenol ethoxylates (NPE-4 and NPE-9) through human, porcine and rat skin
    • Monteiro-Riviere N.A., Van Miller J.P., Simon G., Joiner R.L., Brooks J.D., and Riviere J.E. Comparative in vitro percutaneous absorption of nonylphenol and nonylphenol ethoxylates (NPE-4 and NPE-9) through human, porcine and rat skin. Toxicology and Industrial Health 16 (2000) 49-57
    • (2000) Toxicology and Industrial Health , vol.16 , pp. 49-57
    • Monteiro-Riviere, N.A.1    Van Miller, J.P.2    Simon, G.3    Joiner, R.L.4    Brooks, J.D.5    Riviere, J.E.6
  • 64
    • 0030852002 scopus 로고    scopus 로고
    • In vitro dermal absorption of two commercial formulations of 2, 4-dichlorophenoxyacetic acid dimethylamine (2, 4-D amine) in rat, guinea pig and human skin
    • Moody R.P., and Nadeau B. In vitro dermal absorption of two commercial formulations of 2, 4-dichlorophenoxyacetic acid dimethylamine (2, 4-D amine) in rat, guinea pig and human skin. Toxicology in Vitro 11 (1997) 251-262
    • (1997) Toxicology in Vitro , vol.11 , pp. 251-262
    • Moody, R.P.1    Nadeau, B.2
  • 65
    • 0028104795 scopus 로고
    • In-vitro dermal absorption of pesticides.4. In-vivo and in-vitro comparison with the organophosphorus insecticide diazinon in rat, guinea-pig, pig, human and tissue-cultured skin
    • Moody R.P., and Nadeau B. In-vitro dermal absorption of pesticides.4. In-vivo and in-vitro comparison with the organophosphorus insecticide diazinon in rat, guinea-pig, pig, human and tissue-cultured skin. Toxicology in Vitro 8 (1994) 1213-1218
    • (1994) Toxicology in Vitro , vol.8 , pp. 1213-1218
    • Moody, R.P.1    Nadeau, B.2
  • 66
    • 0027469562 scopus 로고
    • An automated in vitro dermal absorption procedure. 3. In vivo and in vitro comparison with the insect repellent N,N-diethyl-m-toluamide in mouse, rat, guinea-pig, pig, human and tissue-cultured skin
    • Moody R.P., and Nadeau B. An automated in vitro dermal absorption procedure. 3. In vivo and in vitro comparison with the insect repellent N,N-diethyl-m-toluamide in mouse, rat, guinea-pig, pig, human and tissue-cultured skin. Toxicology in Vitro 7 (1993) 167-176
    • (1993) Toxicology in Vitro , vol.7 , pp. 167-176
    • Moody, R.P.1    Nadeau, B.2
  • 67
    • 0028861583 scopus 로고
    • In vivo and in vitro dermal absorption of benzo[a]pyrene in rat, guinea pig, human and tissue-cultured skin
    • Moody R.P., Nadeau B., and Chu I. In vivo and in vitro dermal absorption of benzo[a]pyrene in rat, guinea pig, human and tissue-cultured skin. Journal of Dermatological Science 9 (1995) 48-58
    • (1995) Journal of Dermatological Science , vol.9 , pp. 48-58
    • Moody, R.P.1    Nadeau, B.2    Chu, I.3
  • 68
    • 0025201505 scopus 로고
    • In vitro skin absorption and metabolism of benzoic acid, p-aminobenzoic acid, and benzocaine in the hairless guinea pig
    • Nathan D., Sakr A., Lichtin J.L., and Bronaugh R.L. In vitro skin absorption and metabolism of benzoic acid, p-aminobenzoic acid, and benzocaine in the hairless guinea pig. Pharmaceutical Research 7 (1990) 1147-1151
    • (1990) Pharmaceutical Research , vol.7 , pp. 1147-1151
    • Nathan, D.1    Sakr, A.2    Lichtin, J.L.3    Bronaugh, R.L.4
  • 70
    • 77957181259 scopus 로고
    • Percutaneous absorption/metabolism of phenanthrene in the hairless guinea pig: comparison of in vitro and in vivo results
    • Ng K.M., Chu I., Bronaugh R.L., Franklin C.A., and Somers D.A. Percutaneous absorption/metabolism of phenanthrene in the hairless guinea pig: comparison of in vitro and in vivo results. Fundamental and Applied Toxicology (1991) 517-524
    • (1991) Fundamental and Applied Toxicology , pp. 517-524
    • Ng, K.M.1    Chu, I.2    Bronaugh, R.L.3    Franklin, C.A.4    Somers, D.A.5
  • 72
    • 0029944428 scopus 로고    scopus 로고
    • Differences in penetration-enhancing effect of Azone through excised rabbit, rat, hairless mouse, guinea pig and human skins
    • Niazy E.M. Differences in penetration-enhancing effect of Azone through excised rabbit, rat, hairless mouse, guinea pig and human skins. International Journal of Pharmaceutics 130 (1996) 225-230
    • (1996) International Journal of Pharmaceutics , vol.130 , pp. 225-230
    • Niazy, E.M.1
  • 73
    • 34248582599 scopus 로고    scopus 로고
    • Suitability of excised rabbit ear skin - fresh and frozen - for evaluating transdermal permeation of estradiol
    • Nicoli S., and Santi P. Suitability of excised rabbit ear skin - fresh and frozen - for evaluating transdermal permeation of estradiol. Drug Delivery 14 (2007) 195-199
    • (2007) Drug Delivery , vol.14 , pp. 195-199
    • Nicoli, S.1    Santi, P.2
  • 74
    • 0344334363 scopus 로고    scopus 로고
    • Inter- and intra-individual differences in human stratum corneum lipid content related to physical parameters of skin barrier function in vivo
    • Norlen L., Nicander I., Lundh R.B., Ollmar S., and Forslind B. Inter- and intra-individual differences in human stratum corneum lipid content related to physical parameters of skin barrier function in vivo. Journal of Investigative Dermatology 112 (1999) 72-77
    • (1999) Journal of Investigative Dermatology , vol.112 , pp. 72-77
    • Norlen, L.1    Nicander, I.2    Lundh, R.B.3    Ollmar, S.4    Forslind, B.5
  • 78
    • 0021029860 scopus 로고
    • The octanol-water partitioning of some hydrophobic and hydrophilic compounds
    • Platford R.F. The octanol-water partitioning of some hydrophobic and hydrophilic compounds. Chemosphere 12 (1983) 1107-1111
    • (1983) Chemosphere , vol.12 , pp. 1107-1111
    • Platford, R.F.1
  • 79
    • 0025150867 scopus 로고
    • Evaluation of in-vitro percutaneous absorption across human skin and in animal models
    • Priborsky J., and Muhlbachova E. Evaluation of in-vitro percutaneous absorption across human skin and in animal models. Journal of Pharmacy and Pharmacology 42 (1990) 468-472
    • (1990) Journal of Pharmacy and Pharmacology , vol.42 , pp. 468-472
    • Priborsky, J.1    Muhlbachova, E.2
  • 84
    • 0024998531 scopus 로고
    • Comparisons of in vitro nitroglycerin (TNG) flux across yucatan pig, hairless mouse, and human skins
    • Roberts M.E., and Mueller K.R. Comparisons of in vitro nitroglycerin (TNG) flux across yucatan pig, hairless mouse, and human skins. Pharmaceutical Research 7 (1990) 673-676
    • (1990) Pharmaceutical Research , vol.7 , pp. 673-676
    • Roberts, M.E.1    Mueller, K.R.2
  • 87
    • 0035857715 scopus 로고    scopus 로고
    • Comparison of human skin or epidermis models with human and animal skin in in-vitro percutaneous absorption
    • Schmook F.P., Meingassner J.G., and Billich A. Comparison of human skin or epidermis models with human and animal skin in in-vitro percutaneous absorption. International Journal of Pharmaceutics 215 (2001) 51-56
    • (2001) International Journal of Pharmaceutics , vol.215 , pp. 51-56
    • Schmook, F.P.1    Meingassner, J.G.2    Billich, A.3
  • 88
    • 0025371488 scopus 로고
    • The in vitro percutaneous-absorption of diquat - a species comparison
    • Scott R.C., and Corrigan M.A. The in vitro percutaneous-absorption of diquat - a species comparison. Toxicology in Vitro 4 (1990) 137-141
    • (1990) Toxicology in Vitro , vol.4 , pp. 137-141
    • Scott, R.C.1    Corrigan, M.A.2
  • 89
    • 0025847128 scopus 로고
    • The influence of skin structure on permeability: an intersite and interspecies comparison with hydrophilic penetrants
    • Scott R.C., Corrigan M.A., Smith F., and Mason H. The influence of skin structure on permeability: an intersite and interspecies comparison with hydrophilic penetrants. Journal of Investigative Dermatology 96 (1991) 921-925
    • (1991) Journal of Investigative Dermatology , vol.96 , pp. 921-925
    • Scott, R.C.1    Corrigan, M.A.2    Smith, F.3    Mason, H.4
  • 90
    • 84986360493 scopus 로고
    • A comparison of the in vitro permeability properties of human and some laboratory-animal skins
    • Scott R.C., Walker M., and Dugard P.H. A comparison of the in vitro permeability properties of human and some laboratory-animal skins. International Journal of Cosmetic Science 8 (1986) 189-194
    • (1986) International Journal of Cosmetic Science , vol.8 , pp. 189-194
    • Scott, R.C.1    Walker, M.2    Dugard, P.H.3
  • 91
    • 0033839691 scopus 로고    scopus 로고
    • The pig as an experimental animal model of percutaneous permeation in man: qualitative and quantitative observations - an overview
    • Simon G.A., and Maibach H.I. The pig as an experimental animal model of percutaneous permeation in man: qualitative and quantitative observations - an overview. Skin Pharmacology and Applied Skin Physiology 13 (2000) 229-234
    • (2000) Skin Pharmacology and Applied Skin Physiology , vol.13 , pp. 229-234
    • Simon, G.A.1    Maibach, H.I.2
  • 92
    • 0036166247 scopus 로고    scopus 로고
    • In vitro permeability and binding of hydrocarbons in pig ear and human abdominal skin
    • Singh S., Zhao K., and Singh J. In vitro permeability and binding of hydrocarbons in pig ear and human abdominal skin. Drug and Chemical Toxicology 25 (2002) 83-92
    • (2002) Drug and Chemical Toxicology , vol.25 , pp. 83-92
    • Singh, S.1    Zhao, K.2    Singh, J.3
  • 93
    • 0037345026 scopus 로고    scopus 로고
    • Investigation of newborn pig skin as an in vitro animal model for transdermal drug delivery
    • Songkro S., Purwo Y., Becket G., and Rades T. Investigation of newborn pig skin as an in vitro animal model for transdermal drug delivery. Stp Pharma Sciences 13 (2003) 133-139
    • (2003) Stp Pharma Sciences , vol.13 , pp. 133-139
    • Songkro, S.1    Purwo, Y.2    Becket, G.3    Rades, T.4
  • 95
    • 0025043877 scopus 로고
    • Metabolism of xenobiotics during percutaneous penetration: role of absorption rate and cutaneous enzyme activity
    • Storm J.E., Collier S.W., Stewart R.F., and Bronaugh R.L. Metabolism of xenobiotics during percutaneous penetration: role of absorption rate and cutaneous enzyme activity. Fundamental and Applied Toxicology 15 (1990) 132-141
    • (1990) Fundamental and Applied Toxicology , vol.15 , pp. 132-141
    • Storm, J.E.1    Collier, S.W.2    Stewart, R.F.3    Bronaugh, R.L.4
  • 96
    • 0942276892 scopus 로고    scopus 로고
    • Cutaneous toxicity of chemical irritants on hairless Guinea pigs
    • Sueki H., and Kligman A.M. Cutaneous toxicity of chemical irritants on hairless Guinea pigs. Journal of Dermatology 30 (2003) 859-870
    • (2003) Journal of Dermatology , vol.30 , pp. 859-870
    • Sueki, H.1    Kligman, A.M.2
  • 97
    • 0033764139 scopus 로고    scopus 로고
    • Hairless guinea pig skin: anatomical basis for studies of cutaneous biology
    • Sueki H., Kudoh K., and Kligman A.M. Hairless guinea pig skin: anatomical basis for studies of cutaneous biology. European Journal of Dermatology 10 (2000) 357-364
    • (2000) European Journal of Dermatology , vol.10 , pp. 357-364
    • Sueki, H.1    Kudoh, K.2    Kligman, A.M.3
  • 99
    • 0035991630 scopus 로고    scopus 로고
    • Effects of low-frequency ultrasound on the transdermal permeation of mannitol: comparative studies with in vivo and in vitro skin
    • Tang H., Blankschtein D., and Langer R. Effects of low-frequency ultrasound on the transdermal permeation of mannitol: comparative studies with in vivo and in vitro skin. Journal of Pharmaceutical Sciences 91 (2002) 1776-1794
    • (2002) Journal of Pharmaceutical Sciences , vol.91 , pp. 1776-1794
    • Tang, H.1    Blankschtein, D.2    Langer, R.3
  • 100
    • 0030278908 scopus 로고    scopus 로고
    • Terbutaline transdermal delivery: preformulation studies and limitations of in-vitro predictive parameters
    • Tenjarla S., Puranajoti P., Kasina R., and Mandal T. Terbutaline transdermal delivery: preformulation studies and limitations of in-vitro predictive parameters. Journal of Pharmacy and Pharmacology 48 (1996) 1138-1142
    • (1996) Journal of Pharmacy and Pharmacology , vol.48 , pp. 1138-1142
    • Tenjarla, S.1    Puranajoti, P.2    Kasina, R.3    Mandal, T.4
  • 102
    • 0013867690 scopus 로고
    • The permeability of skin to albumin, dextrans and polyvinyl pyrrolidone
    • Tregear R.T. The permeability of skin to albumin, dextrans and polyvinyl pyrrolidone. Journal of Investigative Dermatology 46 (1966) 24-27
    • (1966) Journal of Investigative Dermatology , vol.46 , pp. 24-27
    • Tregear, R.T.1
  • 105
    • 58149176783 scopus 로고    scopus 로고
    • US EPA, 1992. Dermal Exposure Assessment: Principles and Applications. EPA/600/8-91/011B.
    • US EPA, 1992. Dermal Exposure Assessment: Principles and Applications. EPA/600/8-91/011B.
  • 107
    • 3242659177 scopus 로고    scopus 로고
    • Transdermal delivery of the synthetic cannabinoid WIN 55, 212-2: in vitro/in vivo correlation
    • Valiveti S., Hammell D.C., Earles D.C., and Stinchcomb A.L. Transdermal delivery of the synthetic cannabinoid WIN 55, 212-2: in vitro/in vivo correlation. Pharmaceutical Research 21 (2004) 1137-1145
    • (2004) Pharmaceutical Research , vol.21 , pp. 1137-1145
    • Valiveti, S.1    Hammell, D.C.2    Earles, D.C.3    Stinchcomb, A.L.4
  • 108
    • 34547820769 scopus 로고    scopus 로고
    • In vitro percutaneous penetration of organophosphorus compounds using full-thickness and split-thickness pig and human skin
    • Vallet V., Cruz C., Josse D., Bazire A., Lallement G., and Boudry I. In vitro percutaneous penetration of organophosphorus compounds using full-thickness and split-thickness pig and human skin. Toxicology in Vitro 21 (2007) 1182-1190
    • (2007) Toxicology in Vitro , vol.21 , pp. 1182-1190
    • Vallet, V.1    Cruz, C.2    Josse, D.3    Bazire, A.4    Lallement, G.5    Boudry, I.6
  • 109
    • 40049097850 scopus 로고    scopus 로고
    • Percutaneous penetration and distribution of VX using in vitro pig or human excised skin: Validation of demeton-S-methyl as adequate simulant for VX skin permeation investigations
    • Vallet V., Cruz C., Licausi J., Bazire A., Lallement G., and Boudry I. Percutaneous penetration and distribution of VX using in vitro pig or human excised skin: Validation of demeton-S-methyl as adequate simulant for VX skin permeation investigations. Toxicology 246 (2008) 73-82
    • (2008) Toxicology , vol.246 , pp. 73-82
    • Vallet, V.1    Cruz, C.2    Licausi, J.3    Bazire, A.4    Lallement, G.5    Boudry, I.6
  • 110
    • 0027524257 scopus 로고
    • Species-specific cutaneous biotransformation of the pesticide propoxur during percutaneous absorption in vitro
    • van de Sandt J.J., Rutten A.A., and van O.B. Species-specific cutaneous biotransformation of the pesticide propoxur during percutaneous absorption in vitro. Toxicology and Applied Pharmacology 123 (1993) 144-150
    • (1993) Toxicology and Applied Pharmacology , vol.123 , pp. 144-150
    • van de Sandt, J.J.1    Rutten, A.A.2    van, O.B.3
  • 112
    • 29544435909 scopus 로고    scopus 로고
    • In vitro permeation of chromium species through porcine and human skin as determined by capillary electrophoresis-inductively coupled plasma-sector field mass spectrometry
    • Van Lierde V., Chery C.C., Roche N., Monstrey S., Moens L., and Vanhaecke F. In vitro permeation of chromium species through porcine and human skin as determined by capillary electrophoresis-inductively coupled plasma-sector field mass spectrometry. Analytical and Bioanalytical Chemistry 384 (2006) 378-384
    • (2006) Analytical and Bioanalytical Chemistry , vol.384 , pp. 378-384
    • Van Lierde, V.1    Chery, C.C.2    Roche, N.3    Monstrey, S.4    Moens, L.5    Vanhaecke, F.6
  • 113
    • 58149195803 scopus 로고    scopus 로고
    • Animal models: A comparison of permeability coefficients for excised skin from humans and animals
    • Riviere J.E. (Ed), CRC Press, Boca Raton
    • Vecchia B.E., and Bunge A. Animal models: A comparison of permeability coefficients for excised skin from humans and animals. In: Riviere J.E. (Ed). Dermal Absorption Models in Toxicology and Pharmacology (2006), CRC Press, Boca Raton 305-333
    • (2006) Dermal Absorption Models in Toxicology and Pharmacology , pp. 305-333
    • Vecchia, B.E.1    Bunge, A.2
  • 114
    • 0242629869 scopus 로고
    • In vitro percutaneous-absorption studies - a comparison of human and laboratory species
    • Walker M., Dugard P.H., and Scott R.C. In vitro percutaneous-absorption studies - a comparison of human and laboratory species. Human Toxicology 2 (1983) 561-562
    • (1983) Human Toxicology , vol.2 , pp. 561-562
    • Walker, M.1    Dugard, P.H.2    Scott, R.C.3
  • 115
    • 34548156506 scopus 로고    scopus 로고
    • Properties of ceramides and their impact on the stratum corneum structure: a review
    • Wartewig S., and Neubert R.H.H. Properties of ceramides and their impact on the stratum corneum structure: a review. Skin Pharmacology and Physiology 20 (2007) 220-229
    • (2007) Skin Pharmacology and Physiology , vol.20 , pp. 220-229
    • Wartewig, S.1    Neubert, R.H.H.2
  • 116
    • 0000624759 scopus 로고
    • Drill V.A., and Lazar P. (Eds), Academic, New York
    • Wester R., and Maibach H. In: Drill V.A., and Lazar P. (Eds). Cutaneous Toxicology (1977), Academic, New York 111
    • (1977) Cutaneous Toxicology , pp. 111
    • Wester, R.1    Maibach, H.2


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