Chromatographic indexes on immobilized artificial membranes for the prediction of transdermal transport of drugs

Farmaco

Volumn 53, Issue 10-11, 1998, Pages 655-661

  Barbato, Francesco ^a   Cappello, Brunella ^a   Miro, Agnese ^a   La Rotonda, Maria Immacolata ^a   Quaglia, Fabiana ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Immobilized artificial membranes; Lipophilicity; Skin permeation

Indexed keywords

BENZOIC ACID; CAFFEINE; FUROSEMIDE; GRISEOFULVIN; HYDROCORTISONE; INDOMETACIN; ISOSORBIDE DINITRATE; KETOPROFEN; MINOXIDIL; NAPROXEN; PHOSPHOLIPID; SALICYLIC ACID; THEOPHYLLINE;

ARTICLE; ARTIFICIAL MEMBRANE; BILAYER MEMBRANE; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG TRANSPORT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPOPHILICITY; PARTITION COEFFICIENT; PREDICTION; TRANSDERMAL DRUG ADMINISTRATION;

EID: 0032461067     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(98)00082-2     Document Type: Article

References (28)

1. G. Flynn, E. Linn, T. Kurihara Bergstrom, S. Govil, S. Hou, Transdermal Delivery of Drugs, CRC, Boca Raton, FL, 1987, pp. 3-17.
2. P. Elias, Epidermal lipids, membranes, and keratinization, Int. J. Dermatol. 20 (1981) 1.
3. R. Scheuplein, Mechanism of percutaneous absorption. I. Routes of penetration and the influence of solubility, J. Invest. Dermatol. 45 (1965) 334-346.
4. R. Scheuplein, P. Elias, Percutaneous absorption of steroids, J. Invest. Dermatol. 52 (1969) 63-70.
5. N. El Tayar, R. Tsai, B. Testa, P. Carrupt, C. Hansch, A. Leo, Percutaneous penetration of drugs: a quantitative structure-permeability relationship study, J. Pharm. Sci. 80 (1991) 744-749.
6. W. Stein, Transport and Diffusion Across Cell Membranes, Academic Press, Orlando, FL, 1986.
7. J. Hank, R. Guy, Membrane models for skin permeation studies, Chem. Rev. 88 (1988) 455-471.
8. R. Wester, H. Maibach, In vivo animal models for percutaneous absorption, in: R. Bronaugh, H. Maibach (Eds.), Percutaneous Absorption, vol. 6, Marcel Dekker, New York, 1985, pp. 251-266.
9. A. Leo, C. Hansch, D. Elkins, Partition coefficients and their use, Chem. Rev. 71 (1972) 525-616.
10. A.J. Leo, Methods of calculating partition coefficients, in: C. Hansch, P.G. Sammes, J.B. Taylor (Eds.), Comprehensive Medicinal Chemistry, Pergamon, New York, 1990, pp. 295-319.
11. oct from structures, Chem. Rev. 93 (1993) 1281-1306.
12. L.R. Snyder, J.J. Kirkland, Introduction to Modern Liquid Chromatography, Wiley, New York, 1979.
13. H. Kubinyi, Progress in Drug Research, Jucker Verlag, Basel, 1979, p. 97.
14. H. Turnhofer, J. Schnabel, M. Betz, G. Lipka, C. Pidgeon, H. Hauser, Cholesterol-transfer protein located in the intestinal brush-border membrane, partial purification and characterization, Biochem. Biophys. Acta 1064 (1991) 275-286.
15. F. Barbato, M.I. La Rotonda, F. Quaglia, Chromatografic indices determined on an immobilized artificial membrane (IAM) column as descriptors of lipophilic and polar interactions of 4-DHPs calcium-channel blockers with biomembranes, Eur. J. Med. Chem. 31 (1996) 311-318.
16. F. Barbato, M.I. La Rotonda, F. Quaglia, Interaction of non steroidal antiinflammmatory drugs with phospholipids: comparison between n-octanol/buffer partition coefficients and chromatographic indexes on immobilized artificial membranes, J. Pharm. Sci. 86 (1997) 225-229.
17. F. Barbato, M.I. La Rotonda, F. Quaglia, Chromatographic indexes on immobilized artificial membranes for local anesthetics: relationships with activity data on closed sodium channels, Pharm. Res. 14 (1997) 1699-1705.
18. M. Amato, F. Barbato, M.I. La Rotonda, P. Morrica, F. Quaglia, Interactions between scarcely lipophilic amines and phospholipids measured by chromatography on immobilized artificial membranes (1998) submitted for publication.
19. R.P. Austin, A.M. Davis, C.N. Manners, Partitioning of ionizing molecules between aqueous buffers and phospholipid vesicles, J. Pharm. Sci. 84 (1995) 1180-1183.
20. P. Barton, A.M. Davis, D. McCarthy, P. Webborn, Drug-phospholipids interactions. 2. Predicting the sites of drug distribution using n-octanol/water and membrane/water distribution coefficients, J. Pharm. Sci. 86 (1997) 9.
21. F. Alvarez, C. Bottom, P. Chikale, C. Pidgeon, Immobilized artificial membrane chromatography. Prediction of drug transport across biological barriers, in: T. Ngo (Ed.), Molecular Interactions in Bioseparations, Plenum, New York, 1993.
22. M.H. Abraham, H.S. Chadha, R.A.E. Leitao, R.C. Mitchell, W.J. Lambert, R. Kaliszan, A. Nasal, P. Haber, Determination of solute lipophilicity, as log P(octanol) and log P(alkane) using poly(styrene-divinylbenzene) and immobilised artificial membrane stationary phases in reversed-phase high-performance liquid chromatography, J. Chromatogr. A 766 (1997) 35-47.
23. R. Kaliszan, A. Nasal, A. Bucinski, Chromatographic hydrophobicity parameter determined on an immobilized artificial membrane column: relationships to standard measures of hydrophobicity and bioactivity, Eur. J. Med. Chem. 29 (1994) 163-170.
24. G. Kasting, L. Smith, E. Cooper, Skin pharmacokinetics, in: B. Shroot, H. Schaefer (Eds.), Pharmacology and the Skin, vol. 1, Karger, Basel, 1987, pp. 138-153.
25. W. Albery, J. Hadgraft, Percutaneous absorption: in vivo experiments, J. Pharm. Pharmacol. 31 (1979) 140-147.
26. P. Seiler, Interconversion of lipophilicities from hydrocarbon/ water systems into the octanol/water systems, Eur. J. Med. Chem. 9 (1974) 473-479.
27. P. Seiler, Eur. J. Med. Chem. 9 (1974) 473-479.
28. N. El Tayar, R. Tsai, B. Testa, P. Carrupt, A. Leo, Partitioning of solutes in different solvent systems: the contribution of hydrogen-bonding capacity and polarity, J. Pharm. Sci. 80 (1991) 590-598.