Development of novel diolein-niosomes for cutaneous delivery of tretinoin: Influence of formulation and in vitro assessment

International Journal of Pharmaceutics

Volumn 477, Issue 1-2, 2014, Pages 176-186

  Manca, Maria Letizia ^a   Manconi, Maria ^a   Nacher, Amparo ^b   Carbone, Claudia ^c   Valenti, Donatella ^a   MacCioni, Anna Maria ^a   Sinico, Chiara ^a   Fadda, Anna Maria ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF VALENCIA   (Spain)

^c UNIVERSITY OF CATANIA   (Italy)

Author keywords

Confocal laser scanning microscopy; Labrasol ; Niosomes; SAXS; Skin delivery; Tretinoin

Indexed keywords

GLYCEROL DIOLEATE; LABRASOL; LIPOSOME; NIOSOME; RETINOIC ACID; ACYLGLYCEROL; DIACYLGLYCEROL; DRUG CARRIER;

ARTICLE; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG UPTAKE; FLOW KINETICS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDRATION; HYDROPHILICITY; IN VITRO STUDY; INTERNALIZATION; KERATINOCYTE; LIPID BILAYER; PHYSICAL CHEMISTRY; SKIN APPENDAGE; SKIN PENETRATION; STRATUM CORNEUM; TRANSDERMAL DRUG DELIVERY SYSTEM; X RAY DIFFRACTION; ZETA POTENTIAL; CELL CULTURE; CHEMISTRY; CONFOCAL MICROSCOPY; DRUG EFFECTS; ENDOCYTOSIS; INTRADERMAL DRUG ADMINISTRATION; METABOLISM; PARTICLE SIZE; SKIN; SKIN ABSORPTION; SURFACE PROPERTY;

ADMINISTRATION, CUTANEOUS; CELLS, CULTURED; DIGLYCERIDES; DRUG CARRIERS; DRUG COMPOUNDING; ENDOCYTOSIS; GLYCERIDES; HUMANS; IN VITRO TECHNIQUES; KERATINOCYTES; LIPOSOMES; MICROSCOPY, CONFOCAL; PARTICLE SIZE; RHEOLOGY; SKIN; SKIN ABSORPTION; SURFACE PROPERTIES; TRETINOIN; X-RAY DIFFRACTION;

EID: 84908518364     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.10.031     Document Type: Article

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