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Volumn 17, Issue 3, 2012, Pages 156-165

Penetration of drugs through skin, a complex rate-controlling membrane

Author keywords

Nanoparticles; Skin; Skin absorption; Skin penetration; Stratum corneum; Topical drug delivery

Indexed keywords

AREAS OF CONCERNS; COSMETIC PRODUCTS; CRYSTALLINE STATE; HAIR FOLLICLES; IMMUNE SYSTEMS; MICRO-PARTICLES; PENETRATION MECHANISMS; RATE-CONTROLLING; SKIN ABSORPTION; SKIN PENETRATION; SKIN STRUCTURE; STRATUM CORNEUM; TRANSDERMAL; TRANSDERMAL DELIVERY; VACCINATION STRATEGY;

EID: 84859999642     PISSN: 13590294     EISSN: 18790399     Source Type: Journal    
DOI: 10.1016/j.cocis.2012.02.001     Document Type: Review
Times cited : (225)

References (86)
  • 1
  • 2
    • 0003781922 scopus 로고
    • Marcel Dekker, New York, J. Hadgraft, R.H. Guy (Eds.)
    • Transdermal drug delivery 1989, Marcel Dekker, New York. J. Hadgraft, R.H. Guy (Eds.).
    • (1989) Transdermal drug delivery
  • 5
    • 0020608231 scopus 로고
    • Epidermal lipids, barrier function, and desquamation
    • Elias P.M. Epidermal lipids, barrier function, and desquamation. J Invest Dermatol 1983, 80:44s-49s.
    • (1983) J Invest Dermatol , vol.80
    • Elias, P.M.1
  • 6
    • 0032833887 scopus 로고    scopus 로고
    • Electron diffraction provides new information on human stratum corneum lipid organization studied in relation to depth and temperature
    • Pilgram G.S.K., Engelsma-van Pelt A.M., Bouwstra J.A., Koerten H.K. Electron diffraction provides new information on human stratum corneum lipid organization studied in relation to depth and temperature. J Invest Dermatol 1999, 113:403-409.
    • (1999) J Invest Dermatol , vol.113 , pp. 403-409
    • Pilgram, G.S.K.1    Engelsma-van Pelt, A.M.2    Bouwstra, J.A.3    Koerten, H.K.4
  • 7
    • 77953566528 scopus 로고    scopus 로고
    • Skin lipid organization, composition and barrier function. IFSCC Magazine
    • Bouwstra JA, Gooris GS, Ponec M. Skin lipid organization, composition and barrier function. IFSCC Magazine 2007; 10: 297-307.
    • (2007) , vol.10 , pp. 297-307
    • Bouwstra, J.A.1    Gooris, G.S.2    Ponec, M.3
  • 8
    • 0036853338 scopus 로고    scopus 로고
    • Drug delivery routes in skin: a novel approach
    • Barry B.W. Drug delivery routes in skin: a novel approach. Adv Drug Deliv Rev 2002, 54:S31-S40.
    • (2002) Adv Drug Deliv Rev , vol.54
    • Barry, B.W.1
  • 9
    • 79955599163 scopus 로고    scopus 로고
    • Lipophilicity and its relationship with passive drug permeation
    • Liu X., Testa B., Fahr A. Lipophilicity and its relationship with passive drug permeation. Pharm Res 2011, 28:962-977.
    • (2011) Pharm Res , vol.28 , pp. 962-977
    • Liu, X.1    Testa, B.2    Fahr, A.3
  • 10
    • 0026606514 scopus 로고
    • Predicting skin permeability
    • Potts R.O., Guy R.H. Predicting skin permeability. Pharm Res 1992, 9:663-669.
    • (1992) Pharm Res , vol.9 , pp. 663-669
    • Potts, R.O.1    Guy, R.H.2
  • 11
    • 0031024171 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski C.A., Lombardo F., Dominy B.W., Feeney P.J. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 1997, 23:3-25.
    • (1997) Adv Drug Deliv Rev , vol.23 , pp. 3-25
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 12
    • 79955575780 scopus 로고    scopus 로고
    • The rule of five for non-oral routes of drug delivery: ophthalmic, inhalation and transdermal
    • Choi Y.B., Prausnitz M.R. The rule of five for non-oral routes of drug delivery: ophthalmic, inhalation and transdermal. Pharm Res 2011, 28:943-948.
    • (2011) Pharm Res , vol.28 , pp. 943-948
    • Choi, Y.B.1    Prausnitz, M.R.2
  • 13
    • 20444371510 scopus 로고    scopus 로고
    • Pharmaceutical applications of Mid-IR and Raman spectroscopy
    • Wartewig S., Neubert R.H.H. Pharmaceutical applications of Mid-IR and Raman spectroscopy. Adv Drug Deliv Rev 2005, 57:1144-1147.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1144-1147
    • Wartewig, S.1    Neubert, R.H.H.2
  • 14
    • 67650119490 scopus 로고    scopus 로고
    • Studying the effectiveness of penetration enhancers to deliver retinol through the stratum cornea by in vivo confocal Raman spectroscopy
    • Mélot M., Pudney P.D.A., Williamson A.M., Caspers P.J., Van Der Pol A., Puppels G.J. Studying the effectiveness of penetration enhancers to deliver retinol through the stratum cornea by in vivo confocal Raman spectroscopy. J Control Release 2009, 138:32-39.
    • (2009) J Control Release , vol.138 , pp. 32-39
    • Mélot, M.1    Pudney, P.D.A.2    Williamson, A.M.3    Caspers, P.J.4    Van Der Pol, A.5    Puppels, G.J.6
  • 15
    • 84857847819 scopus 로고    scopus 로고
    • Raman spectroscopy: feasibility of in vivo survey of stratum corneum lipids, effect of natural aging
    • Tfayli A., Guillard E., Manfait M., Baillet-Guffroy A. Raman spectroscopy: feasibility of in vivo survey of stratum corneum lipids, effect of natural aging. Eur J Dermatol 2012, 22:36-41.
    • (2012) Eur J Dermatol , vol.22 , pp. 36-41
    • Tfayli, A.1    Guillard, E.2    Manfait, M.3    Baillet-Guffroy, A.4
  • 16
    • 79955608023 scopus 로고    scopus 로고
    • Ingredients tracking of cosmetic formulations in the skin: a confocal Raman microscopy investigation
    • Förster M., Bolzinger M.A., Ach D., Montagnac G., Briançon S. Ingredients tracking of cosmetic formulations in the skin: a confocal Raman microscopy investigation. Pharm Res 2011, 28:858-872.
    • (2011) Pharm Res , vol.28 , pp. 858-872
    • Förster, M.1    Bolzinger, M.A.2    Ach, D.3    Montagnac, G.4    Briançon, S.5
  • 19
    • 0023274940 scopus 로고
    • Presence of intact intercellular lipid lamellae in the upper layers of the stratum corneum
    • Madison K.C., Swartzendruber D.C., Wertz P.W., Downing D.T. Presence of intact intercellular lipid lamellae in the upper layers of the stratum corneum. J Invest Dermatol 1987, 88:714-718.
    • (1987) J Invest Dermatol , vol.88 , pp. 714-718
    • Madison, K.C.1    Swartzendruber, D.C.2    Wertz, P.W.3    Downing, D.T.4
  • 20
    • 0025955486 scopus 로고
    • Structural Investigations of human stratum corneum by small angle X-ray scattering
    • Bouwstra J.A., Gooris G.S., van der Spek J.A., Bras W. Structural Investigations of human stratum corneum by small angle X-ray scattering. J Invest Dermatol 1991, 97:1005-1012.
    • (1991) J Invest Dermatol , vol.97 , pp. 1005-1012
    • Bouwstra, J.A.1    Gooris, G.S.2    van der Spek, J.A.3    Bras, W.4
  • 21
    • 33845308573 scopus 로고    scopus 로고
    • The skin barrier in healthy and diseased state
    • Bouwstra J.A., Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta Biomembr 2006, 1758:2080-2095.
    • (2006) Biochim Biophys Acta Biomembr , vol.1758 , pp. 2080-2095
    • Bouwstra, J.A.1    Ponec, M.2
  • 22
    • 0027955474 scopus 로고
    • A domain mosaic model of the skin barrier
    • Forslind B. A domain mosaic model of the skin barrier. Acta Derm Venereol 1994, 74:1-6.
    • (1994) Acta Derm Venereol , vol.74 , pp. 1-6
    • Forslind, B.1
  • 24
    • 0034778702 scopus 로고    scopus 로고
    • Skin barrier structure and function: the single gel phase model
    • Norlén L. Skin barrier structure and function: the single gel phase model. J Invest Dermatol 2001, 117:830-836.
    • (2001) J Invest Dermatol , vol.117 , pp. 830-836
    • Norlén, L.1
  • 25
    • 75549090635 scopus 로고    scopus 로고
    • The extent of orthorhombic lipid phases in the stratum corneum determines the barrier efficiency of human skin in vivo
    • Damien F., Boncheva M. The extent of orthorhombic lipid phases in the stratum corneum determines the barrier efficiency of human skin in vivo. J Invest Dermatol 2010, 130:611-614.
    • (2010) J Invest Dermatol , vol.130 , pp. 611-614
    • Damien, F.1    Boncheva, M.2
  • 26
    • 43049147557 scopus 로고    scopus 로고
    • Molecular organization of the lipid matrix in intact stratum corneum using ATR-FTIR spectroscopy
    • Boncheva M., Damien F., Normand V. Molecular organization of the lipid matrix in intact stratum corneum using ATR-FTIR spectroscopy. Biochim Biophys Acta 2008, 1778:1344-1355.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 1344-1355
    • Boncheva, M.1    Damien, F.2    Normand, V.3
  • 27
    • 0036091146 scopus 로고    scopus 로고
    • Does the single gel phase exist in stratum corneum?
    • Bouwstra J.A., Pilgram G.S.K., Ponec M. Does the single gel phase exist in stratum corneum?. J Invest Dermatol 2002, 118:897-898.
    • (2002) J Invest Dermatol , vol.118 , pp. 897-898
    • Bouwstra, J.A.1    Pilgram, G.S.K.2    Ponec, M.3
  • 29
    • 34248579896 scopus 로고    scopus 로고
    • Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films
    • Norlén L., Plasencia Gil I., Simonsen A., Descouts P. Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films. J Struct Biol 2007, 158:386-400.
    • (2007) J Struct Biol , vol.158 , pp. 386-400
    • Norlén, L.1    Plasencia Gil, I.2    Simonsen, A.3    Descouts, P.4
  • 30
    • 79951663616 scopus 로고    scopus 로고
    • Correlation between the properties of the lipid matrix and the degrees of integrity and cohesion in healthy human stratum corneum
    • Berthaud F., Boncheva M. Correlation between the properties of the lipid matrix and the degrees of integrity and cohesion in healthy human stratum corneum. Exp Dermatol 2010, 20:255-262.
    • (2010) Exp Dermatol , vol.20 , pp. 255-262
    • Berthaud, F.1    Boncheva, M.2
  • 31
    • 33644990077 scopus 로고    scopus 로고
    • Thermotropic and spectroscopic behavior of skin: relationship with percutaneous permeation enhancement
    • Babita K., Kumar V., Rana V., Jain S., Tiwary A.K. Thermotropic and spectroscopic behavior of skin: relationship with percutaneous permeation enhancement. Curr Drug Deliv 2006, 3:95-113.
    • (2006) Curr Drug Deliv , vol.3 , pp. 95-113
    • Babita, K.1    Kumar, V.2    Rana, V.3    Jain, S.4    Tiwary, A.K.5
  • 32
    • 70350489623 scopus 로고    scopus 로고
    • Irradiation of skin and contrasting effects on absorption of hydrophilic and lipophilic compounds
    • Duracher L., Blasco L., Jaoued A.A., Vian L., Marti-Mestres G. Irradiation of skin and contrasting effects on absorption of hydrophilic and lipophilic compounds. Photochem Photobiol 2009, 85:1459-1467.
    • (2009) Photochem Photobiol , vol.85 , pp. 1459-1467
    • Duracher, L.1    Blasco, L.2    Jaoued, A.A.3    Vian, L.4    Marti-Mestres, G.5
  • 33
    • 79954720421 scopus 로고    scopus 로고
    • Is an orthorhombic lateral packing and a proper lamellar organization important for the skin barrier function?
    • Groen D., Poole D.S., Gooris G.S., Bouwstra J.A. Is an orthorhombic lateral packing and a proper lamellar organization important for the skin barrier function?. Biochim Biophys Acta Biomembr 2011, 1808:1529-1537.
    • (2011) Biochim Biophys Acta Biomembr , vol.1808 , pp. 1529-1537
    • Groen, D.1    Poole, D.S.2    Gooris, G.S.3    Bouwstra, J.A.4
  • 35
    • 17844373273 scopus 로고    scopus 로고
    • Transdermal drug delivery: penetration enhancement techniques
    • Benson H.A.E. Transdermal drug delivery: penetration enhancement techniques. Curr Drug Deliv 2005, 2:23-33.
    • (2005) Curr Drug Deliv , vol.2 , pp. 23-33
    • Benson, H.A.E.1
  • 36
    • 0002063313 scopus 로고    scopus 로고
    • Structure of fully hydrated human stratum corneum: a freeze-fracture electron microscopy study
    • van Hal D.A., Jeremiasse E., Junginger H.E., Spies F., Bouwstra J.A. Structure of fully hydrated human stratum corneum: a freeze-fracture electron microscopy study. J Invest Dermatol 1996, 106:89-95.
    • (1996) J Invest Dermatol , vol.106 , pp. 89-95
    • van Hal, D.A.1    Jeremiasse, E.2    Junginger, H.E.3    Spies, F.4    Bouwstra, J.A.5
  • 37
    • 70350001743 scopus 로고    scopus 로고
    • Conformational changes in stratum corneum lipids by effect of bicellar systems
    • Rodríguez G., Barbosa-Barros L., Rubio L., Cócera M., Díez A., Estelrich J., et al. Conformational changes in stratum corneum lipids by effect of bicellar systems. Langmuir 2009, 25:10595-10603.
    • (2009) Langmuir , vol.25 , pp. 10595-10603
    • Rodríguez, G.1    Barbosa-Barros, L.2    Rubio, L.3    Cócera, M.4    Díez, A.5    Estelrich, J.6
  • 38
    • 0033071283 scopus 로고    scopus 로고
    • Test guidelines for in vitro assessment of dermal absorption and percutaneous penetration of cosmetic ingredients
    • Diembeck W., Beck H., Benech-Kieffer F., Courtellemont P., Dupuis J., Lovell W., et al. Test guidelines for in vitro assessment of dermal absorption and percutaneous penetration of cosmetic ingredients. Food Chem Toxicol 1999, 37:191-205.
    • (1999) Food Chem Toxicol , vol.37 , pp. 191-205
    • Diembeck, W.1    Beck, H.2    Benech-Kieffer, F.3    Courtellemont, P.4    Dupuis, J.5    Lovell, W.6
  • 39
    • 0343764899 scopus 로고
    • Relative penetrability of hair follicles and epidermis
    • Tregear R.T. Relative penetrability of hair follicles and epidermis. J Physiol 1961, 156:307-313.
    • (1961) J Physiol , vol.156 , pp. 307-313
    • Tregear, R.T.1
  • 40
    • 0026091718 scopus 로고
    • Follicles play an important role in percutaneous absorption
    • Illel B., Schaefer H., Wepierre J., Doucet O. Follicles play an important role in percutaneous absorption. J Pharm Sci 1991, 80:424-427.
    • (1991) J Pharm Sci , vol.80 , pp. 424-427
    • Illel, B.1    Schaefer, H.2    Wepierre, J.3    Doucet, O.4
  • 41
    • 27844497505 scopus 로고    scopus 로고
    • Transfollicular drug delivery-is it a reality?
    • Meidan V.M., Bonnr M.C., Michniak B.B. Transfollicular drug delivery-is it a reality?. Int J Pharm 2005, 306:1-14.
    • (2005) Int J Pharm , vol.306 , pp. 1-14
    • Meidan, V.M.1    Bonnr, M.C.2    Michniak, B.B.3
  • 46
    • 0037426686 scopus 로고    scopus 로고
    • Modeling skin permeability to hydrophilic and hydrophobic solutes based on four permeation pathways
    • Mitragotri S. Modeling skin permeability to hydrophilic and hydrophobic solutes based on four permeation pathways. J Control Release 2003, 86:69-92.
    • (2003) J Control Release , vol.86 , pp. 69-92
    • Mitragotri, S.1
  • 48
    • 80052836975 scopus 로고    scopus 로고
    • Human hair follicle: reservoir function and selective targeting
    • Blume-Peytavi U., Vogt A. Human hair follicle: reservoir function and selective targeting. Br J Dermatol 2011, 165:13-17. (Suppl).
    • (2011) Br J Dermatol , vol.165 , Issue.SUPPL , pp. 13-17
    • Blume-Peytavi, U.1    Vogt, A.2
  • 50
    • 33746326111 scopus 로고    scopus 로고
    • Follicular penetration: development of a method to block the follicles selectively against the penetration of topically applied substances
    • Teichmann A., Otberg N., Jacobi U., Sterry W., Lademann J. Follicular penetration: development of a method to block the follicles selectively against the penetration of topically applied substances. Skin Pharmacol Physiol 2006, 19:216-223.
    • (2006) Skin Pharmacol Physiol , vol.19 , pp. 216-223
    • Teichmann, A.1    Otberg, N.2    Jacobi, U.3    Sterry, W.4    Lademann, J.5
  • 51
    • 77953925317 scopus 로고    scopus 로고
    • Development of an in vitro modified skin absorption test for the investigation of the follicular penetration pathway of caffeine
    • Trauer S., Lademann J., Knorr F., Richter H., Liebsch M., Rozycki C., et al. Development of an in vitro modified skin absorption test for the investigation of the follicular penetration pathway of caffeine. Skin Pharmacol Physiol 2010, 23:320-327.
    • (2010) Skin Pharmacol Physiol , vol.23 , pp. 320-327
    • Trauer, S.1    Lademann, J.2    Knorr, F.3    Richter, H.4    Liebsch, M.5    Rozycki, C.6
  • 52
    • 68449101181 scopus 로고    scopus 로고
    • Permeation of topically applied caffeine through human skin-a comparison of in vivo and in vitro data
    • Trauer S., Patzelt A., Otberg N., Knorr F., Rozycki C., Balizs G., et al. Permeation of topically applied caffeine through human skin-a comparison of in vivo and in vitro data. Br J Clin Pharmacol 2009, 68:181-186.
    • (2009) Br J Clin Pharmacol , vol.68 , pp. 181-186
    • Trauer, S.1    Patzelt, A.2    Otberg, N.3    Knorr, F.4    Rozycki, C.5    Balizs, G.6
  • 56
    • 67449128215 scopus 로고    scopus 로고
    • Comparison of two in vitro models for the analysis of follicular penetration and its prevention by barrier emulsions
    • Lademann J., Patzelt A., Richter H., Schanzer S., Sterry W., Filbry A., et al. Comparison of two in vitro models for the analysis of follicular penetration and its prevention by barrier emulsions. Eur J Pharm Biopharm 2009, 72:600-604.
    • (2009) Eur J Pharm Biopharm , vol.72 , pp. 600-604
    • Lademann, J.1    Patzelt, A.2    Richter, H.3    Schanzer, S.4    Sterry, W.5    Filbry, A.6
  • 57
    • 40049097850 scopus 로고    scopus 로고
    • Percutaneous penetration and distribution of VX using in vitro pig or human excised skin validation of demeton-s-methyl as adequate simulant for VX skin permeation investigations
    • Vallet V., Cruz C., Licausi J., Bazire A., Lallement G., Boudry I. Percutaneous penetration and distribution of VX using in vitro pig or human excised skin validation of demeton-s-methyl as adequate simulant for VX skin permeation investigations. Toxicology 2008, 246:73-82.
    • (2008) Toxicology , vol.246 , pp. 73-82
    • Vallet, V.1    Cruz, C.2    Licausi, J.3    Bazire, A.4    Lallement, G.5    Boudry, I.6
  • 59
    • 80052237832 scopus 로고    scopus 로고
    • Nanoparticles through the skin: managing conflicting results of inorganic and organic particles in cosmetics and pharmaceutics
    • Bolzinger M.-A., Briançon S., Chevalier Y. Nanoparticles through the skin: managing conflicting results of inorganic and organic particles in cosmetics and pharmaceutics. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2011, 3:463-478.
    • (2011) Wiley Interdiscip Rev Nanomed Nanobiotechnol , vol.3 , pp. 463-478
    • Bolzinger, M.-A.1    Briançon, S.2    Chevalier, Y.3
  • 60
    • 28244474457 scopus 로고    scopus 로고
    • Lipid nanoparticles for skin penetration enhancement-correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy
    • Lombardi Borgia S., Regehly M., Sivaramakrishnan R., Mehnert W., Korting H.C., Danker K., et al. Lipid nanoparticles for skin penetration enhancement-correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy. J Control Release 2005, 110:151-163.
    • (2005) J Control Release , vol.110 , pp. 151-163
    • Lombardi Borgia, S.1    Regehly, M.2    Sivaramakrishnan, R.3    Mehnert, W.4    Korting, H.C.5    Danker, K.6
  • 61
    • 75549084961 scopus 로고    scopus 로고
    • Nanotechnology and the transdermal route. A state of the art review and critical appraisal
    • Cevc G., Vierl U. Nanotechnology and the transdermal route. A state of the art review and critical appraisal. J Control Release 2010, 141:277-299.
    • (2010) J Control Release , vol.141 , pp. 277-299
    • Cevc, G.1    Vierl, U.2
  • 62
    • 79952363000 scopus 로고    scopus 로고
    • Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy
    • Roberts M.S., Dancik Y., Prow T.W., Thorling C.A., Lin L.L., Grice J.E., et al. Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy. Eur J Pharm Biopharm 2011, 77:469-488.
    • (2011) Eur J Pharm Biopharm , vol.77 , pp. 469-488
    • Roberts, M.S.1    Dancik, Y.2    Prow, T.W.3    Thorling, C.A.4    Lin, L.L.5    Grice, J.E.6
  • 64
    • 33645469482 scopus 로고    scopus 로고
    • Stem cells and their niches
    • Moore K.A., Lemischka I.R. Stem cells and their niches. Science 2006, 311:1880-1885.
    • (2006) Science , vol.311 , pp. 1880-1885
    • Moore, K.A.1    Lemischka, I.R.2
  • 66
  • 67
    • 33750728433 scopus 로고    scopus 로고
    • Targeting dendritic cells with biomaterials: developing the next generation of vaccines
    • Reddy S.T., Swartz M.A., Hubbell J.A. Targeting dendritic cells with biomaterials: developing the next generation of vaccines. Trends Immunol 2006, 27:573-579.
    • (2006) Trends Immunol , vol.27 , pp. 573-579
    • Reddy, S.T.1    Swartz, M.A.2    Hubbell, J.A.3
  • 68
    • 65249092828 scopus 로고    scopus 로고
    • Nanoparticle-based targeting of vaccine compounds to skin antigen-presenting cells by hair follicles and their transport in mice
    • Mahé B., Vogt A., Liard C., Duffy D., Abadie V., Bonduelle O., et al. Nanoparticle-based targeting of vaccine compounds to skin antigen-presenting cells by hair follicles and their transport in mice. J Invest Dermatol 2009, 129:1156-1164.
    • (2009) J Invest Dermatol , vol.129 , pp. 1156-1164
    • Mahé, B.1    Vogt, A.2    Liard, C.3    Duffy, D.4    Abadie, V.5    Bonduelle, O.6
  • 69
    • 74449084205 scopus 로고    scopus 로고
    • Multifunctional core-shell polymeric nanoparticles for transdermal DNA delivery and epidermal Langerhans cells tracking
    • Lee P.W., Hsu S.H., Tsai J.S., Chen F.R., Huang P.J., Ke C.J., et al. Multifunctional core-shell polymeric nanoparticles for transdermal DNA delivery and epidermal Langerhans cells tracking. Biomaterials 2010, 31:2425-2434.
    • (2010) Biomaterials , vol.31 , pp. 2425-2434
    • Lee, P.W.1    Hsu, S.H.2    Tsai, J.S.3    Chen, F.R.4    Huang, P.J.5    Ke, C.J.6
  • 70
    • 33745518414 scopus 로고    scopus 로고
    • 40nm, but not 750 or 1,500nm, nanoparticles enter epidermal CD1a+ cells after transcutaneous application on human skin
    • Vogt A., Combadière B., Hadam S., Stieler K.M., Lademann J., Schaefer H., et al. 40nm, but not 750 or 1,500nm, nanoparticles enter epidermal CD1a+ cells after transcutaneous application on human skin. J Invest Dermatol 2006, 126:1316-1322.
    • (2006) J Invest Dermatol , vol.126 , pp. 1316-1322
    • Vogt, A.1    Combadière, B.2    Hadam, S.3    Stieler, K.M.4    Lademann, J.5    Schaefer, H.6
  • 71
    • 47049100427 scopus 로고    scopus 로고
    • Nanoparticles target distinct dendritic cell populations according to their size
    • Manolova V., Flace A., Bauer M., Schwarz K., Saudan P., Bachmann M.F. Nanoparticles target distinct dendritic cell populations according to their size. Eur J Immunol 2008, 38:1404-1413.
    • (2008) Eur J Immunol , vol.38 , pp. 1404-1413
    • Manolova, V.1    Flace, A.2    Bauer, M.3    Schwarz, K.4    Saudan, P.5    Bachmann, M.F.6
  • 72
    • 0027137165 scopus 로고
    • Site-specific drug delivery to pilosebaceous structures using polymeric microspheres
    • Rolland A., Wagner N., Chatelus A., Shroot B., Schaefer H. Site-specific drug delivery to pilosebaceous structures using polymeric microspheres. Pharm Res 1993, 10:1738-1744.
    • (1993) Pharm Res , vol.10 , pp. 1738-1744
    • Rolland, A.1    Wagner, N.2    Chatelus, A.3    Shroot, B.4    Schaefer, H.5
  • 73
    • 44849143985 scopus 로고    scopus 로고
    • Nanotechnology, cosmetics and the skin: is there a health risk?
    • Nohynek G.J., Dufour E.K., Roberts M.S. Nanotechnology, cosmetics and the skin: is there a health risk?. Skin Pharmacol Physiol 2008, 21:136-149.
    • (2008) Skin Pharmacol Physiol , vol.21 , pp. 136-149
    • Nohynek, G.J.1    Dufour, E.K.2    Roberts, M.S.3
  • 74
    • 33845752957 scopus 로고    scopus 로고
    • In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen
    • Mavon A., Miquel C., Lejeune O., Payre B., Moretto P. In vitro percutaneous absorption and in vivo stratum corneum distribution of an organic and a mineral sunscreen. Skin Pharmacol Physiol 2007, 20:10-20.
    • (2007) Skin Pharmacol Physiol , vol.20 , pp. 10-20
    • Mavon, A.1    Miquel, C.2    Lejeune, O.3    Payre, B.4    Moretto, P.5
  • 75
    • 72449126230 scopus 로고    scopus 로고
    • Interaction of nanomaterials with skin: aspects of absorption and biodistribution
    • Monteiro-Riviere N.A., Riviere J.E. Interaction of nanomaterials with skin: aspects of absorption and biodistribution. Nanotoxicology 2009, 3:188-193.
    • (2009) Nanotoxicology , vol.3 , pp. 188-193
    • Monteiro-Riviere, N.A.1    Riviere, J.E.2
  • 76
    • 77958477177 scopus 로고    scopus 로고
    • Nanomaterial penetration
    • Informa Healthcare, New York, N.A. Monteiro-Riviere (Ed.) Toxicology of the skin
    • Monteiro-Riviere N.A., Baroli B. Nanomaterial penetration. Target Organ Toxicology Series. 2010, 22:333-346. Informa Healthcare, New York. N.A. Monteiro-Riviere (Ed.).
    • (2010) Target Organ Toxicology Series. , vol.22 , pp. 333-346
    • Monteiro-Riviere, N.A.1    Baroli, B.2
  • 78
    • 33645800783 scopus 로고    scopus 로고
    • Penetration of intact skin by quantum dots with diverse physicochemical properties
    • Ryman-Rasmussen J.P., Riviere J.E., Monteiro-Riviere N.A. Penetration of intact skin by quantum dots with diverse physicochemical properties. Toxicol Sci 2006, 91:159-165.
    • (2006) Toxicol Sci , vol.91 , pp. 159-165
    • Ryman-Rasmussen, J.P.1    Riviere, J.E.2    Monteiro-Riviere, N.A.3
  • 79
    • 33846883504 scopus 로고    scopus 로고
    • Effects of mechanical flexion on the penetration of fullerene amino acid-derivatized peptide nanoparticles through skin
    • Rouse J.G., Yang J., Ryman-Rasmussen J.P., Barron A.R., Monteiro-Riviere N.A. Effects of mechanical flexion on the penetration of fullerene amino acid-derivatized peptide nanoparticles through skin. Nano Lett 2007, 7:155-160.
    • (2007) Nano Lett , vol.7 , pp. 155-160
    • Rouse, J.G.1    Yang, J.2    Ryman-Rasmussen, J.P.3    Barron, A.R.4    Monteiro-Riviere, N.A.5
  • 81
    • 54549113498 scopus 로고    scopus 로고
    • In vivo skin penetration of quantum dot nanoparticles in the murine model: the effect of UVR
    • Mortensen L.J., Oberdörster G., Pentland A.P., DeLouise L.A. In vivo skin penetration of quantum dot nanoparticles in the murine model: the effect of UVR. Nano Lett 2008, 8:2779-2787.
    • (2008) Nano Lett , vol.8 , pp. 2779-2787
    • Mortensen, L.J.1    Oberdörster, G.2    Pentland, A.P.3    DeLouise, L.A.4
  • 82
    • 44749086736 scopus 로고    scopus 로고
    • In vitro permeation of gold nanoparticles through rat skin and rat intestine: effect of particle size
    • Sonavane G., Tomoda K., Sano A., Ohshima H., Terada H., Makino K. In vitro permeation of gold nanoparticles through rat skin and rat intestine: effect of particle size. Colloids Surf B Biointerfaces 2008, 65:1-10.
    • (2008) Colloids Surf B Biointerfaces , vol.65 , pp. 1-10
    • Sonavane, G.1    Tomoda, K.2    Sano, A.3    Ohshima, H.4    Terada, H.5    Makino, K.6
  • 83
  • 84
    • 41549109750 scopus 로고    scopus 로고
    • Biological interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes
    • Zhang L.W., Yu W.W., Colvin V.L., Monteiro-Riviere N.A. Biological interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes. Toxicol Appl Pharmacol 2008, 228:200-211.
    • (2008) Toxicol Appl Pharmacol , vol.228 , pp. 200-211
    • Zhang, L.W.1    Yu, W.W.2    Colvin, V.L.3    Monteiro-Riviere, N.A.4
  • 85
    • 62149086939 scopus 로고    scopus 로고
    • Qualitative detection of single submicron and nanoparticles in human skin by scanning transmission X-ray microscopy
    • Graf C., Meinke M., Gao Q., Hadam S., Raabe J., Sterry W., et al. Qualitative detection of single submicron and nanoparticles in human skin by scanning transmission X-ray microscopy. J Biomed Opt 2009, 14:021015.
    • (2009) J Biomed Opt , vol.14 , pp. 021015
    • Graf, C.1    Meinke, M.2    Gao, Q.3    Hadam, S.4    Raabe, J.5    Sterry, W.6
  • 86
    • 34948909248 scopus 로고    scopus 로고
    • Biodistribution of quantum dot nanoparticles in perfused skin: evidence of coating dependency and periodicity in arterial extraction
    • Lee H.A., Imran M., Monteiro-Riviere N.A., Colvin V.L., Yu W.W., Riviere J.E. Biodistribution of quantum dot nanoparticles in perfused skin: evidence of coating dependency and periodicity in arterial extraction. Nano Lett 2007, 7:2865-2870.
    • (2007) Nano Lett , vol.7 , pp. 2865-2870
    • Lee, H.A.1    Imran, M.2    Monteiro-Riviere, N.A.3    Colvin, V.L.4    Yu, W.W.5    Riviere, J.E.6


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