Comparative percutaneous permeation study using caffeine-loaded microemulsion showing low reliability of the frozen/thawed skin models

International Journal of Pharmaceutics

Volumn 471, Issue 1-2, 2014, Pages 516-524

  Sintov, Amnon C ^a   Greenberg, Igor ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Caffeine; Microemulsion; Percutaneous permeation; Porcine skin; Skin models; Transdermal drug delivery

Indexed keywords

CAFFEINE; CERAMIDE; CHOLESTEROL; WATER; DRUG CARRIER; EMULSION; MICELLE; OIL; SURFACTANT;

ANIMAL EXPERIMENT; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; ELECTRIC CONDUCTIVITY; FREEZE THAWING; HYDROPHILICITY; HYPOTHESIS; IN VITRO STUDY; LIPOPHILICITY; MICROEMULSION; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT; RELIABILITY; SKIN PERMEABILITY; STORAGE; STRATUM CORNEUM; SWINE; WATER CONTENT; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; EMULSION; METABOLISM; MICELLE; PARTICLE SIZE; PERMEABILITY; SKIN; SKIN ABSORPTION; SPECIES DIFFERENCE; SPRAGUE DAWLEY RAT;

ANIMALS; CAFFEINE; DRUG CARRIERS; EMULSIONS; MICELLES; MODELS, BIOLOGICAL; OILS; PARTICLE SIZE; PERMEABILITY; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SKIN; SKIN ABSORPTION; SPECIES SPECIFICITY; SURFACE-ACTIVE AGENTS; SWINE;

EID: 84903378931     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.05.040     Document Type: Article

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