The genetic and epigenetic alterations in human hepatocellular carcinoma: A recent update

Protein and Cell

Volumn 5, Issue 9, 2014, Pages 673-691

  Liu, Ming ^a   Jiang, Lingxi ^a   Guan, Xin Yuan ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

cancer hallmarks; epigenetic regulation; genetic regulation; HCC progression; hepatocellular carcinoma (HCC); therapeutic targets

Indexed keywords

ANGIOPOIETIN 2; AXIN; B RAF KINASE; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; FIBROBLAST GROWTH FACTOR; FRIZZLED PROTEIN; GELATINASE A; GELATINASE B; LONG UNTRANSLATED RNA; MICRORNA; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PHOSPHATIDYLINOSITOL 3, 4, 5 TRISPHOSPHATE 3 PHOSPHATASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN MDM2; PROTEIN P18; PROTEIN P53; SCATTER FACTOR RECEPTOR; SOMATOMEDIN B RECEPTOR; SOMATOMEDIN C RECEPTOR; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTOME; UNCLASSIFIED DRUG; UNINDEXED DRUG; UVOMORULIN; VASCULOTROPIN;

ANGIOGENESIS; APOPTOSIS; CANCER GROWTH; CANCER STAGING; CANCER STEM CELL; CANCER SUSCEPTIBILITY; CELL DEATH; CELL DIVISION; CELL PROLIFERATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOMAL INSTABILITY; DNA METHYLATION; ENERGY METABOLISM; EPIGENETICS; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GENE MUTATION; GENE REGULATORY NETWORK; GENETIC REGULATION; HISTONE MODIFICATION; HUMAN; LIVER CELL CARCINOMA; MALIGNANT TRANSFORMATION; METASTASIS; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; REVIEW; RNA EDITING; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR ESCAPE; TUMOR INVASION; TUMOR MICROENVIRONMENT; TUMOR SUPPRESSOR GENE;

EID: 84929134719     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-014-0065-9     Document Type: Review

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