Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c

Cell Metabolism

Volumn 15, Issue 5, 2012, Pages 725-738

  Hagiwara, Asami ^a   Cornu, Marion ^a   Cybulski, Nadine ^a   Polak, Pazit ^a   Betz, Charles ^a   Trapani, Francesca ^b   Terracciano, Luigi ^b   Heim, Markus H ^c   Rüegg, Markus A ^a   Hall, Michael N ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOKINASE; GLUCOSE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PROTEIN KINASE B; PROTEIN KINASE B BETA; SERINE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRANSCRIPTION FACTOR FKHR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; GLUCONEOGENESIS; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; GLYCOLYSIS; HOMEOSTASIS; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPOLIPEMIA; LIPID METABOLISM; LIPOGENESIS; LIVER; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SATIETY;

ANIMALS; FORKHEAD TRANSCRIPTION FACTORS; GLUCOKINASE; GLUCONEOGENESIS; GLUCOSE; GLUCOSE INTOLERANCE; GLYCOGEN SYNTHASE KINASE 3; GLYCOLYSIS; HEPATOCYTES; HOMEOSTASIS; HYPERGLYCEMIA; HYPERINSULINISM; INSULIN; LIPID METABOLISM; LIPOGENESIS; LIVER; MALE; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANS-ACTIVATORS;

MAMMALIA; MUS;

EID: 84860454425     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2012.03.015     Document Type: Article

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